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Tomohiko Taguchi

Tohoku University

42H指数
192论文数
6.2K被引数
收录论文 63
发表时间
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An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activationN端CDC42 T43I变异体揭示了pyrin炎性小体的激活机制
errScience Immunology
IF16.3
err2026-08-07
err0
PREAI
errMariko Aoki; Alberto Iannuzzo; Philippe Mertz; Shouya Feng; Naoya Iwata; Chiara Perugini; Naomi Tsuchida; Rana El Masri; Yoshihiko Kuchitsu; Rachida Tacine; Simona Coppola; Hirofumi Shibata; Margaux Cescato; Masahiko Nishitani-Isa; Alexandre Terré; Yuri Kawasaki; Sarah Dalmon; Kenichi Nishimura; Flora Magnotti; Satoko Miyatake; Marc André; Keisuke Hamada; Jonathan London; Kazushi Izawa; Akira Niwa; Nobuhiko Okamoto; Kazuhiro Ogata; Masashi Nishikawa; Erika Zara; Megumu K. Saito; Marco Tartaglia; Shuichi Ito; Mathieu P. Rodero; Koh-ichi Nagata; Asma Smahi; Naomichi Matsumoto; Laurent Le Corre; Junko Takita; Guilaine Boursier; Atsushi Hijikata; Thomas Henry; Tomohiko Taguchi; Véronique Hentgen; Sophie Georgin-Lavialle; Yoshitaka Honda; Seth L. Masters; Takahiro Yasumi; Jérôme Delon
err分享
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A genotype-first approach reveals the molecular basis of pyrin inflammasome activation以基因型为先导的方法揭示了pyrin炎性小体活化的分子基础
errScience Immunology
IF16.3
err2026-08-07
err0
PREAI
errNaoya Iwata; Yoshihiko Kuchitsu; Atsushi Hijikata; Hirofumi Shibata; Masahiko Nishitani-Isa; Mariko Aoki; Kazushi Izawa; Hiroyuki Yoshitomi; Junko Takita; Hideki Ueno; Tomohiko Taguchi; Takahiro Yasumi; Yoshitaka Honda
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A PI(3,5)P2/CHMP4B axis on lysosomes is essential for microautophagic degradation of STING溶酶体上的PI(3,5)P2/CHMP4B轴对于STING的微自噬降解至关重要
errNature Communications
IF15.7
err2026-05-27
err0
errOAAI
errTsumugi Shoji; Ayumi Shinojima; Takuma Kishimoto; Kanako Sato; Nana Ikegami; Eisuke Yumoto; Ruri Shindo; Yasunori Uchida; Satoshi Kusumi; Daisuke Koga; Eiji Yamamoto; Yoshinori Hirano; Ryo Ogino; Hirofumi Shibata; Kazushi Izawa; Takahiro Yasumi; Ryota Sato; Jun Nakayama; Shigeki Higashiyama; Junya Hasegawa; Hiroaki Kajiho; Takehiko Sasaki; Yoshihiko Kuchitsu; Tomohiko Taguchi
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Visualizing Newly Synthesized Proteins and Their Degradation Dynamics by Using Long-Wavelength-Emitting Fluorescent Dye-DBCO Conjugates利用长波长发射荧光染料-DBCO缀合物可视化新合成蛋白质及其降解动力学
errBioconjugate Chemistry
IF3.9
err2026-04-01
err0
PREAI
errSumitani, Shun; Sasaki, Eita; Ohno, Hisashi; Yamada, Sota; Takayama, Orie; Wei, Fan-Yan; Kuchitsu, Yoshihiko; Taguchi, Tomohiko; Hanaoka, Kenjiro
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Microautophagy: definition, classification, and the complexity of the underlying mechanisms微自噬：定义、分类及其底层的机制复杂性
errAutophagy
IF14.3
err2025-09-18
err0
PREAI
errYasuyoshi Sakai; Christian Behrends; Ana Maria Cuervo; Jayanta Debnath; Masanori Izumi; Andreas Jenny; Maurizio Molinari; Shuhei Nakamura; Masahide Oku; Marisa S. Otegui; Laura Santambrogio; Han-Ming Shen; Tomohiko Taguchi; Michael Thumm; Takashi Ushimaru; Zhiping Xie; Fulvio Reggiori
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Reelin Increases the Sphingomyelin Content of the Plasma Membrane and Affects the Surface Expression of GPI-Anchored Proteins in Hippocampal NeuronsReelin增加了海马神经元质膜的鞘磷脂含量，并影响糖基磷脂酰肌醇锚定蛋白的表面表达。
errJournal of Neurochemistry
IF4
err2025-09-03
err0
errOAAI
errYuto Takekoshi; Hugo Ando; Takao Kohno; Hiroshi Takase; Tomohiko Taguchi; Makoto Arita; Toshihide Kobayashi; Mitsuharu Hattori
err分享
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Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism腺苷激酶和ADAL协同调节修饰型腺苷的解毒作用以保护代谢过程
errCell
IF42.5
err2025-08-20
err0
errOAAI
errAkiko Ogawa; Satoshi Watanabe; Iuliia Ozerova; Allen Yi-Lun Tsai; Yoshihiko Kuchitsu; Harrison Byron Chong; Tomoyoshi Kawakami; Jirio Fuse; Wei Han; Ryuhei Kudo; Tomoki Naito; Kota Sato; Toru Nakazawa; Yasunori Saheki; Akiyoshi Hirayama; Peter F Stadler; Mieko Arisawa; Kimi Araki; Liron Bar-Peled; Tomohiko Taguchi; Shinichiro Sawa; Kenji Inaba; Fan-Yan Wei
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Single-molecule imaging quantifies oncogenic KRAS dynamics for enhanced accuracy of therapeutic efficacy assessment单分子成像定量分析致癌性KRAS动力学，以提高治疗疗效评估的准确性。
erriScience
IF4.1
err2025-08-14
err0
PREAI
errRyoma Yokoi; Toshiki Mori; Koichiro M. Hirosawa; Ryojiro Kondo; Tomohiko Taguchi; Nobuhisa Matsuhashi; Kenichi G.N. Suzuki
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Membrane-domain compartmentalization of active GPCRs by β-arrestins through PtdIns(4,5)P2 binding通过PtdIns(4,5)P2结合，β-arrestins对活性GPCRs的膜域区室化。
errNature Chemical Biology
IF13.7
err2025-08-06
err0
errOAAI
errRitsuki Kuramoto; Tatsuya Ikuta; Carlo Marion C. Carino; Kouki Kawakami; Miisha Kushiro; Chihiro Watanabe; Yasunori Uchida; Mitsuhiro Abe; Yasushi Sako; Tomohiko Taguchi; Masataka Yanagawa; Asuka Inoue
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Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria共轭脂肪酸通过靶向线粒体通过伴侣介导的GPX4自噬降解驱动铁死亡
errCELL DEATH & DISEASE
IF9.6
err2024-12-06
err1
errOAAI
errHirata, Yusuke; Yamada, Yuto; Taguchi, Soma; Kojima, Ryota; Masumoto, Haruka; Kimura, Shinnosuke; Niijima, Takuya; Toyama, Takashi; Kise, Ryoji; Sato, Emiko; Uchida, Yasunori; Ito, Junya; Nakagawa, Kiyotaka; Taguchi, Tomohiko; Inoue, Asuka; Saito, Yoshiro; Noguchi, Takuya; Matsuzawa, Atsushi
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A non-toxic equinatoxin-II reveals the dynamics and distribution of sphingomyelin in the cytosolic leaflet of the plasma membrane
errSCIENTIFIC REPORTS
IF3.9
err2024-07-23
err1
errOAAI
errMori, Toshiki; Niki, Takahiro; Uchida, Yasunori; Mukai, Kojiro; Kuchitsu, Yoshihiko; Kishimoto, Takuma; Sakai, Shota; Makino, Asami; Kobayashi, Toshihide; Arai, Hiroyuki; Yokota, Yasunari; Taguchi, Tomohiko; Suzuki, Kenichi G. N.
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Lysosomal microautophagy: an emerging dimension in mammalian autophagy溶酶体微自噬: 哺乳动物自噬的新兴维度
errTRENDS IN CELL BIOLOGY
IF18.1
err2024-07-01
err13
errOAAI
errKuchitsu, Yoshihiko; Taguchi, Tomohiko
err分享
err收藏
Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-04-24
err1
errOAAI
errKaryu, Hitomi; Niki, Takahiro; Sorimachi, Yuriko; Hata, Shoji; Shimabukuro-Demoto, Shiho; Hirabayashi, Tetsuya; Mukai, Kojiro; Kasahara, Kohji; Takubo, Keiyo; Goda, Nobuhito; Honke, Koichi; Taguchi, Tomohiko; Sorimachi, Hiroyuki; Toyama-Sorimachi, Noriko
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STINGing organelle surface with acid用酸刺痛细胞器表面
errEMBO REPORTS
IF6.2
err2024-03-19
err1
errOAAI
errKuchitsu, Yoshihiko; Taguchi, Tomohiko
err分享
err收藏
Mentoring the next generation of cell biologists
errNATURE CELL BIOLOGY
IF19.1
err2024-01-16
err0
PREAI
errApplewhite, Derek A.; Bhalla, Needhi; Cabezas-Wallscheid, Nina; Erez, Neta; Li, Mengfeng; Polo, Jose M.; Taguchi, Tomohiko; Thiam, Abdou Rachid; Wang, Xiaochen
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Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol单分子定位显微镜揭示了通过棕榈酰化依赖性胆固醇积累在反式高尔基体网络上的STING聚集
errNATURE COMMUNICATIONS
IF15.7
err2024-01-11
err6
errOAAI
errKemmoku, Haruka; Takahashi, Kanoko; Mukai, Kojiro; Mori, Toshiki; Hirosawa, Koichiro M.; Kiku, Fumika; Uchida, Yasunori; Kuchitsu, Yoshihiko; Nishioka, Yu; Sawa, Masaaki; Kishimoto, Takuma; Tanaka, Kazuma; Yokota, Yasunari; Arai, Hiroyuki; Suzuki, Kenichi G. N.; Taguchi, Tomohiko
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err收藏
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activationPPP1R12A是一种促进YAP激活的循环内体磷酸酶
errSCIENTIFIC REPORTS
IF3.9
err2023-11-13
err4
errOAAI
errInoue, Chiaki; Mukai, Kojiro; Matsudaira, Tatsuyuki; Nakayama, Jun; Kono, Nozomu; Aoki, Junken; Arai, Hiroyuki; Uchida, Yasunori; Taguchi, Tomohiko
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TLR7/8 stress response drives histiocytosis in SLC29A3 disordersTLR7/8应激反应驱动SLC29A3疾病中的组织细胞增生症
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-07-18
err8
errOAAI
errShibata, Takuma; Sato, Ryota; Taoka, Masato; Saitoh, Shin-Ichiroh; Komine, Mayumi; Yamaguchi, Kiyoshi; Goyama, Susumu; Motoi, Yuji; Kitaura, Jiro; Izawa, Kumi; Yamauchi, Yoshio; Tsukamoto, Yumiko; Ichinohe, Takeshi; Fujita, Etsuko; Hiranuma, Ryosuke; Fukui, Ryutaro; Furukawa, Yoichi; Kitamura, Toshio; Takai, Toshiyuki; Tojo, Arinobu; Ohtsuki, Mamitaro; Ohto, Umeharu; Shimizu, Toshiyuki; Ozawa, Manabu; Yoshida, Nobuaki; Isobe, Toshiaki; Latz, Eicke; Mukai, Kojiro; Taguchi, Tomohiko; Hemmi, Hiroaki; Akira, Shizuo; Miyake, Kensuke
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err收藏
STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomesSTING信号通过ESCRT依赖性的源自再循环内体的囊泡微自噬终止
errNATURE CELL BIOLOGY
IF19.1
err2023-03-13
err61
errOAAI
errKuchitsu, Yoshihiko; Mukai, Kojiro; Uematsu, Rei; Takaada, Yuki; Shinojima, Ayumi; Shindo, Ruri; Shoji, Tsumugi; Hamano, Shiori; Ogawa, Emari; Sato, Ryota; Miyake, Kensuke; Kato, Akihisa; Kawaguchi, Yasushi; Nishitani-Isa, Masahiko; Izawa, Kazushi; Nishikomori, Ryuta; Yasumi, Takahiro; Suzuki, Takehiro; Dohmae, Naoshi; Uemura, Takefumi; Barber, Glen N. N.; Arai, Hiroyuki; Waguri, Satoshi; Taguchi, Tomohiko
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Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2022-04-28
err25
errOAAI
errNishitani-Isa, Masahiko; Mukai, Kojiro; Honda, Yoshitaka; Nihira, Hiroshi; Tanaka, Takayuki; Shibata, Hirofumi; Kodama, Kumi; Hiejima, Eitaro; Izawa, Kazushi; Kawasaki, Yuri; Osawa, Mitsujiro; Katata, Yu; Onodera, Sachiko; Watanabe, Tatsuya; Uchida, Takashi; Kure, Shigeo; Takita, Junko; Ohara, Osamu; Saito, Megumu K.; Nishikomori, Ryuta; Taguchi, Tomohiko; Sasahara, Yoji; Yasumi, Takahiro
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