Michiel van der Flier

Utrecht University

H指数:31

被引数:3,900

个人简介

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教育背景

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工作经历

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荣誉奖项

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Excessive C5 conversion prevents C9 polymerisation and subsequent MAC-dependent killing of Klebsiella pneumoniae

过度的C5转化阻止了C9聚合及随后依赖MAC的肺炎克雷伯菌杀伤

PLoS Pathogens

IF4.9

2026-05-111

Predicting trajectories of illness using RNA velocity of whole blood

利用全血RNA速度预测疾病轨迹

Nature Communications

IF15.7

2026-05-060

OAAI

Claire Dunican; Clare Wilson; Dominic Habgood-Coote; Suzanna Paterson; Mahdad Noursadeghi; Raymond Moseki; Cari Stek; Robert J. Wilkinson; Philipp K. A. Agyeman; Coco R. Beudeker; Giske Biesbroek; Ulrich von Both; Karen Brengel-Pesce; Enitan D. Carrol; Lachlan J. M. Coin; Giselle D’Souza; Tisham De; Marieke Emonts; Katy Fidler; Colin G. Fink; Michiel van der Flier; Ioanna Georgaki; Laura Kolberg; Mojca Kolnik; Taco Kuijpers; Federico Martinón-Torres; Marine Mommert-Tripon; Samuel Nichols; Stephane Paulus; Marko Pokorn; Andrew J. Pollard; Irene Rivero-Calle; Aleksandra Rudzate; Luregn J. Schlapbach; Nina A. Schweintzger; Ching-Fen Shen; Shrijana Shrestha; Chantal D. Tan; Maria Tsolia; Effua Usuf; Fabian van der Velden; Clementien L. Vermont; Marie Voice; Shunmay Yeung; Dace Zavadska; Werner Zenz; Victoria J. Wright; Michael Levin; Jethro Herberg; Rachel P. J. Lai; Graeme Meintjes; Christopher Chiu; Mauricio Barahona; Myrsini Kaforou; Aubrey J. Cunnington

Genetic Determinants of the Complement and Coagulation Pathways in Invasive Meningococcal Disease

侵袭性脑膜炎球菌病中补体和凝血通路的遗传决定因素

Journal of Allergy and Clinical Immunology

IF11.2

2025-09-210

OAAI

Evangelos Bellos; Karin van Leeuwen; Amedine Duret; Stephanie Hodeib; Meg Mashbat; Daniela S. Kohlfuerst; Navin P. Boeddha; Luregn J. Schlapbach; Victoria J. Wright; Colin G. Fink; Michiel van der Flier; Marcel van Deuren; Tom Sprong; Margarita López Trascasa; Alberto López Lera; Federico Martinón-Torres; Antonio Salas; Dilys Santillo; Werner Zenz; Gertjan J. Driessen; Suzanne T. Anderson; Fatou Secka; Stephane Paulus; Ronald de Groot; Marieke Emonts; Enitan D. Carrol; Jethro Herberg; Mike Levin; Vanessa Sancho-Shimizu; Taco Kuijpers

A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia

一种5转录本特征，用于区分儿童肺炎的病毒性和细菌性病因

ISCIENCE

IF4.1

2025-02-011

OAAI

Viz-Lasheras, Sandra; Gomez-Carballa, Alberto; Pardo-Seco, Jacobo; Bello, Xabier; Rivero-Calle, Irene; Dacosta, Ana Isabel; Kaforou, Myrsini; Habgood-Coote, Dominic; Cunnington, Aubrey J.; Emonts, Marieke; Herberg, Jethro A.; Wright, Victoria J.; Carrol, Enitan D.; Paulus, Stephane C.; Zenz, Werner; Kohlfuerst, Daniela S.; van der Flier, Michiel; de Groot, Ronald; Schlapbach, Luregn J.; Agyeman, Philipp; Pollard, Andrew J.; Fink, Colin; Kuijpers, Taco T.; Anderson, Suzanne; Calvo, Cristina; Martinez-Padilla, Maria del Carmen; Perez-Aragon, Ana; Gomez-Sanchez, Esteban; Valencia-Ramos, Juan; Gimenez-Sanchez, Francisco; Alonso-Quintela, Paula; Moreno-Galarraga, Laura; von Both, Ulrich; Pokorn, Marko; Zavadska, Dace; Tsolia, Maria; Vermont, Clementien L.; Moll, Henriette A.; Levin, Michael; Martinon-Torres, Federico; EUCLIDS Consortium; DIAMONDS Consortium; GENDRES Consortium; PERFORM Consortium

A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study

LANCET DIGITAL HEALTH

IF24.1

2023-11-0110

OAAI

Jackson, Heather R.; Zandstra, Judith; Menikou, Stephanie; Hamilton, Melissa Shea; Mcardle, Andrew J.; Fischer, Roman; Thorne, Adam M.; Huang, Honglei; Tanck, Michael W.; Jansen, Machiel H.; De, Tisham; Agyeman, Philipp K. A.; Von Both, Ulrich; Carrol, Enitan; Emonts, Marieke; Eleftheriou, Irini; van der Flier, Michiel; Fink, Colin; Gloerich, Jolein; De Groot, Ronald; Moll, Henriette A.; Pokorn, Marko; Pollard, Andrew J.; Schlapbach, Luregn J.; Tsolia, Maria N.; Usuf, Effua; Wright, Victoria J.; Yeung, Shunmay; Zavadska, Dace; Zenz, Werner; Coin, Lachlan J. M.; Casals-Pascual, Climent; Cunnington, Aubrey J.; Martinon-Torres, Federico; Herberg, Jethro A.; de Jonge, Marien, I; Levin, Michael; Kuijpers, Taco W.; Kaforou, Myrsini

Raising AWaRe-ness of Antimicrobial Stewardship Challenges in Pediatric Emergency Care: Results from the PERFORM Study Assessing Consistency and Appropriateness of Antibiotic Prescribing Across Europe

提高儿科急诊护理中抗菌药物管理挑战的意识: PERFORM研究评估欧洲抗生素处方的一致性和适当性的结果

CLINICAL INFECTIOUS DISEASES

IF7.3

2023-10-114

OAAI

Kolberg, Laura; Khanijau, Aakash; van der Velden, Fabian J. S.; Herberg, Jethro; De, Tisham; Galassini, Rachel; Cunnington, Aubrey J.; Wright, Victoria J.; Shah, Priyen; Kaforou, Myrsini; Wilson, Clare; Kuijpers, Taco; Martinon-Torres, Federico; Rivero-Calle, Irene; Moll, Henriette; Vermont, Clementien; Pokorn, Marko; Kolnik, Mojca; Pollard, Andrew J.; Agyeman, Philipp K. A.; Schlapbach, Luregn J.; Tsolia, Maria N.; Yeung, Shunmay; Zavadska, Dace; Zenz, Werner; Schweintzger, Nina A.; van der Flier, Michiel; de Groot, Ronald; Usuf, Effua; Voice, Marie; Calvo-Bado, Leonides; Mallet, Francois; Fidler, Katy; Levin, Michael; Carrol, Enitan D.; Emonts, Marieke; von Both, Ulrich

Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study

LANCET REGIONAL HEALTH-EUROPE

IF13

2023-09-0110

Shah, Priyen; Voice, Marie; Calvo-Bado, Leonides; Rivero-Calle, Irene; Morris, Sophie; Nijman, Ruud; Broderick, Claire; De, Tisham; Eleftheriou, Irini; Galassini, Rachel; Khanijau, Aakash; Kolberg, Laura; Kolnik, Mojca; Rudzate, Aleksandra; Sagmeister, Manfred G.; Schweintzger, Nina A.; Secka, Fatou; Thakker, Clare; van der Velden, Fabian; Vermont, Clementien; Vincek, Katarina; Agyeman, Philipp K. A.; Cunnington, Aubrey J.; De Groot, Ronald; Emonts, Marieke; Fidler, Katy; Kuijpers, Taco W.; Mommert-Tripon, Marine; Brengel-Pesce, Karen; Mallet, Francois; Moll, Henriette; Paulus, Stephane; Pokorn, Marko; Pollard, Andrew; Schlapbach, Luregn J.; Shen, Ching-Fen; Tsolia, Maria; Usuf, Effua; van der Flier, Michiel; von Both, Ulrich; Yeung, Shunmay; Zavadska, Dace; Zenz, Werner; Wright, Victoria; Carrol, Enitan D.; Kaforou, Myrsini; Martinon-Torres, Federico; Fink, Colin; Levin, Michael; Herberg, Jethro

Development and clinical impact assessment of a machine-learning model for early prediction of late-onset sepsis

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2023-09-0110

OAAI

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature

MED

IF11.8

2023-09-0113

Habgood-Coote, Dominic; Wilson, Clare; Shimizu, Chisato; Barendregt, Anouk M.; Philipsen, Ria; Galassini, Rachel; Calle, Irene Rivero; Workman, Lesley; Agyeman, Philipp K. A.; Ferwerda, Gerben; Anderson, Suzanne T.; van den Berg, J. Merlijn; Emonts, Marieke; Carrol, Enitan D.; Fink, Colin G.; de Groot, Ronald; Hibberd, Martin L.; Kanegaye, John; Nicol, Mark P.; Paulus, Stephane; Pollard, Andrew J.; Salas, Antonio; Secka, Fatou; Schlapbach, Luregn J.; Tremoulet, Adriana H.; Walther, Michael; Zenz, Werner; van der Flier, Michiel; Zar, Heather J.; Kuijpers, Taco; Burns, Jane C.; Martinon-Torres, Federico; Wright, Victoria J.; Coin, Lachlan J. M.; Cunnington, Aubrey J.; Herberg, Jethro A.; Levin, Michael; Kaforou, Myrsini

Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study

欧洲急诊部门发热儿童的紧急医疗服务利用情况: 一项观察性多中心研究

EUROPEAN JOURNAL OF PEDIATRICS

IF2.6

2023-06-244

OAAI

Febrile illness in high-risk children: a prospective, international observational study (Vol 182, pg 543, 2023)

EUROPEAN JOURNAL OF PEDIATRICS

IF2.6

2023-01-230

OAAI

van der Velden, Fabian J. S.; de Vries, Gabriella; Martin, Alexander; Lim, Emma; von Both, Ulrich; Kolberg, Laura; Carrol, Enitan D.; Khanijau, Aakash; Herberg, Jethro A.; Tisham De; Galassini, Rachel; Kuijpers, Taco W.; Martinon-Torres, Federico; Rivero-Calle, Irene; Vermont, Clementien L.; Hagedoorn, Nienke N.; Pokorn, Marko; Pollard, Andrew J.; Schlapbach, Luregn J.; Tsolia, Maria; Elefhteriou, Irini; Yeung, Shunmay; Zavadska, Dace; Fink, Colin; Voice, Marie; Zenz, Werner; Kohlmaier, Benno; Agyeman, Philipp K. A.; Usuf, Effua; Secka, Fatou; de Groot, Ronald; Levin, Michael; van der Flier, Michiel; Emonts, Marieke

Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study (Sept, 10.1007/s00431-022-04606-5, 2022)

EUROPEAN JOURNAL OF PEDIATRICS

IF2.6

2022-10-210

OAAI

Neonatal sepsis and transient immunodeficiency: Potential for novel immunoglobulin therapies?

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-10-1810

OAAI

Febrile illness in high-risk children: a prospective, international observational study

高危儿发热性疾病: 一项前瞻性国际观察性研究

EUROPEAN JOURNAL OF PEDIATRICS

IF2.6

2022-10-154

OAAI

van der Velden, Fabian J. S.; de Vries, Gabriella; Martin, Alexander; Lim, Emma; von Both, Ulrich; Kolberg, Laura; Carrol, Enitan D.; Khanijau, Aakash; Herberg, Jethro A.; De, Tisham; Galassini, Rachel; Kuijpers, Taco W.; Martinon-Torres, Federico; Rivero-Calle, Irene; Vermont, Clementien L.; Hagedoorn, Nienke N.; Pokorn, Marko; Pollard, Andrew J.; Schlapbach, Luregn J.; Tsolia, Maria; Elefhteriou, Irini; Yeung, Shunmay; Zavadska, Dace; Fink, Colin; Voice, Marie; Zenz, Werner; Kohlmaier, Benno; Agyeman, Philipp K. A.; Usuf, Effua; Secka, Fatou; de Groot, Ronald; Levin, Michael; van der Flier, Michiel; Emonts, Marieke

Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study

EUROPEAN JOURNAL OF PEDIATRICS

IF2.6

2022-09-306

OAAI

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations

CFHR3的变化通过控制因子H的浓度来确定对脑膜炎球菌病的易感性

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-09-015

OAAI

Kumar, Vikrant; Pouw, Richard B.; Autio, Matias, I; Sagmeister, Manfred G.; Phua, Zai Yang; Borghini, Lisa; Wright, Victoria J.; Hoggart, Clive; Pan, Bangfen; Tan, Antson Kiat Yee; Binder, Alexander; Brouwer, Mieke C.; Pinnock, Ellie; De Groot, Ronald; Hazelzet, Jan; Emonts, Marieke; van der Flier, Michiel; Reiter, Karl; Nothen, Markus M.; Hoffmann, Per; Schlapbach, Luregn J.; Bellos, Evangelos; Anderson, Suzanne; Secka, Fatou; Martinon-Torres, Federico; Salas, Antonio; Fink, Colin; Carrol, Enitan D.; Pollard, Andrew J.; Coin, Lachlan J.; Zenz, Werner; Wouters, Diana; Ang, Lay Teng; Hibberd, Martin L.; Levin, Michael; Kuijpers, Taco W.; Davila, Sonia

Non-invasive diagnostics of pathogenic bacteria using a breath sampler in children with cystic fibrosis

JOURNAL OF BREATH RESEARCH

IF3.4

2022-08-094