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P

Petr Man

czech academy of sciences

H指数:35

被引数:4,735

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De novo EHMT2 variants cause an autosomal dominant EHMT2-related Kleefstra syndrome via loss of G9a methyltransferase activity

新发EHMT2基因变异通过丧失G9a甲基转移酶活性导致常染色体显性遗传的EHMT2相关Kleefstra综合征

Nature Communications

IF15.7

2026-07-010

OAAI

Aleš Hnízda; Beatriz Martinez-Delgado; Diana Sanchez-Ponce; Javier Alonso; Jeanne Amiel; Tania Attie-Bitach; Ariadna Bada-Navarro; Beatriz Baladron; Eva Bermejo-Sanchez; Vítězslav Brinsa; Ivana Buková; Rosario Cazorla-Calleja; Sylvie Červenková; Shanshan Chow; Petr Dušek; Olha Fedosieieva; Marta Fernandez-Prieto; Sourav Ghosh; Gema Gomez-Mariano; Andrea Gřegořová; Mark James Hamilton; Hana Hartmannová; Esther Hernandez-SanMiguel; Marina Herrero-Matesanz; Kateřina Hodaňová; Alan Kádek; Jennifer Kerkhof; Tjitske Kleefstra; Didier Lacombe; Michael A. Levy; Estrella Lopez-Martin; Ruaud Lyse; Petr Man; Purificacion Marin-Reina; Ellen F. Macnamara; Haley McConkey; Petra Melenovská; Lidia M. Mielu; David Moore; Lenka Steiner Mrázová; Karolína Musilová; Kristýna Neffeová; Petr Nickl; David Pajuelo Reguera; Martina Pavlíková; Lea Pavlovičová; Manuel Posada; Jan Procházka; Kateryna Pysanenko; Sheila Ramos del Saz; Dmitrijs Rots; Jessica Rzasa; Radislav Sedláček; Viktor Stránecký; František Špoutil; Matthew L. Tedder; Louise Thompson; Cynthia J. Tifft; Frederic Tran Mau-Them; Helena Trešlová; Antonio Vitobello; Sarah Hilton; Christopher Campbell; Siddharth Banka; Daniel Jirák; Bekim Sadikovic; Jakub Sikora; Stanislav Kmoch; Maria J. Barrero; Lenka Nosková

Calcium-loaded acylated segment controls membrane penetration capacity of repeats-in-toxin cytolysins

钙负载酰化片段控制重复毒素细胞毒素的膜穿透能力

Journal of Biological Chemistry

IF3.9

2026-04-270

OAAI

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

人源NQO1同源二聚体底物结合位点处的酪氨酸残基：蛋白质构象动力学及底物结合几何构型的优化

IF4.2

2026-03-010

PRE

Molecular mechanism of exchange coupling in CLC chloride/proton antiporters

CLC氯离子/质子反转运蛋白交换耦合的分子机制

Nature Communications

IF15.7

2026-01-080

OAAI

Nanobodies as therapies for loss-of-function misfolding diseases: the example of Primary Hyperoxaluria Type 1

International Journal of Biological Macromolecules

IF8.5

2025-12-300

OAAI

The cryo-EM structure of Photosystem I from Chromera velia with a bound superoxide dismutase heterodimer

来自Chromera velia的光系统I的cryo-em结构与结合的超氧化物歧化酶异二聚体

Nature Communications

IF15.7

2025-12-210

OA

Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex

人类顺式烯醇转移酶复合物中别构调节的结构机制

Nature Communications

IF15.7

2025-11-280

OAAI

New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands, and transcriptional coregulators

关于DNA、配体和转录共调节因子对视黄酸受体RAR/RXR调控的新结构见解

NUCLEIC ACIDS RESEARCH

IF13.1

2025-10-140

OAAI

A somatic multiple myeloma mutation unravels a mechanism of oligomerization-mediated product inhibition in GGPPS

一种体细胞多发性骨髓瘤突变揭示了GGPPS中寡聚化介导的产物抑制机制

IF0

2025-07-070

OAAI

Postproline Cleaving Enzymes also Show Specificity to Reduced Cysteine

ANALYTICAL CHEMISTRY

IF6.7

2024-11-190

OAAI

Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer

IF4.2

2024-09-060

OAAI

Structural Characterization of Monoclonal Antibodies and Epitope Mapping by FFAP Footprinting

ANALYTICAL CHEMISTRY

IF6.7

2024-05-031

OAAI

Structural dynamics of Na+ and Ca2+ interactions with full-size mammalian NCX

COMMUNICATIONS BIOLOGY

IF5.1

2024-04-162

OAAI

Chloride intracellular channel (CLIC) proteins function as fusogens

NATURE COMMUNICATIONS

IF15.7

2024-03-072

OAAI

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

IF3

2024-01-192

PRE

A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin-independent cell penetration

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-08-012

OAAI

Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease (vol 6, 30980, 2016)

SCIENTIFIC REPORTS

IF3.9

2023-01-180

OAAI

Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme

IF4.2

2022-11-252

OA

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

SCIENTIFIC REPORTS

IF3.9

2022-10-136

OAAI

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

通过磷酸模拟突变研究的癌症相关NQO1酶中的位点特异性磷酸化导致的不同表型结果

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2022-10-014

OAAI