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Yongsheng Che

Institute of Medicinal Biotechnology

49H指数
186论文数
1.2W被引数
收录论文 95
发表时间
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Better antiviral and lung-protective effects of Carrimycin in combination with Azvudine in rhesus macaques infected with SARS-CoV-2卡里霉素与阿兹夫定联用对感染SARS-CoV-2的恒河猴具有更好的抗病毒和肺保护作用
errJournal of Translational Medicine
IF7.5
err2026-09-07
err0
errOAAI
errHu Li; Yunpeng Liu; Jing Xue; Jianrui Li; Jingchen Xu; Biao Dong; Tong Wang; Xiaozhong Peng; Yongsheng Che; Jiandong Jiang; Zonggen Peng
err分享
err收藏
Secoemestrin C exerts rapid and prominent anti-breast cancer effect in triple-negative breast cancer by inducing SLX4 and YAP degradationSecoemestrin C通过诱导SLX4和YAP降解，对三阴性乳腺癌产生快速且显著的抗乳腺癌效果。
errActa Pharmacologica Sinica
IF8.4
err2026-01-12
err0
PREAI
errXiao-jun Zhao; Yang Xu; Cong-hui Zhang; Cong Zhao; Li Liu; Xiao-wei Wang; Meng-yan Wang; Zi-xiang Gao; Rong-guang Shao; Li-qiang Qi; Yong-sheng Che; Wu-li Zhao
err分享
err收藏
Design, Synthesis, and Biological Evaluation of Novel Core Scaffold-Modified HIV-1 Protease Inhibitors for Overcoming Drug Resistance
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-10-01
err0
PREAI
errZhou, Huiyu; Gao, Yu; Yang, Qingqing; Shan, Qi; Meng, Sihan; Ma, Ling; Dong, Biao; Wang, Juxian; Zhang, Guoning; Wang, Minghua; Cen, Shan; Wang, Yucheng; Che, Yongsheng; Zhu, Mei
err分享
err收藏
Anti-MRSA anthrone–macrolide hybrids from the ascomycete fungus Neonectria sp.来自子囊菌真菌Neonectria sp.的抗MRSA蒽酮-大环内酯杂化物
errChinese Chemical Letters
IF8.9
err2025-09-02
err0
PREAI
errJinwei Ren; Ruiyun Huo; Xiaoqi Sun; Guobo Guan; Ying Shi; Yangyang Han; Yongsheng Che; Ling Liu
err分享
err收藏
Mycophenolate mofetil exerts broad-spectrum antiviral activity against coronaviruses including SARS-CoV-2
errVIROLOGY JOURNAL
IF3.8
err2025-03-04
err0
errOAAI
errWu, Mengyuan; Wang, Kun; Wang, Huiqiang; Yan, Haiyan; Wu, Shuo; Yang, Ge; Li, Yuhuan; Che, Yongsheng; Jiang, Jiandong
err分享
err收藏
Phomaketals A and B, pentacyclic meroterpenoids from a eupC overexpressed mutant strain of Phoma sp.
errCHINESE CHEMICAL LETTERS
IF8.9
err2024-07-01
err2
PREAI
errLi, Chuan; Han, Yangyang; Zhai, Yanan; Li, Ke; Liu, Xingzhong; Zhang, Zhuan; Jia, Cai; Che, Yongsheng
err分享
err收藏
Rogersonins C-F, 9H-Imidazo[2,1-i]purine-Incorporating Adenine-Polyketide Hybrids from an Ophiocordyceps-Associated Clonostachys rogersoniana
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-06-18
err0
PREAI
errHou, Xintong; Wang, Ruikun; Zhang, Chunyan; Xu, Yang; Zhu, Shuaiming; Zhang, Yang; Liu, Xingzhong; Che, Yongsheng
err分享
err收藏
Lachnochromonin, a fungal metabolite from Lachnum virgineum, inhibits cell growth and promotes apoptosis in tumor cells through JAK/ STAT3 signaling
errCELLULAR SIGNALLING
IF3.7
err2023-06-01
err2
PREAI
errChu, Jun; Zhai, Wanli; Geng, Yongtao; Feng, Yarui; Wang, Jiayu; Li, Jun; Wang, Yinyin; Zhuang, Wenying; Che, Yongsheng; Li, Yi; Chang, Zhijie; Ren, Fangli
err分享
err收藏
Altersteroids A-D, 9,11-Secosteroid-Derived γ-Lactones from an Alternaria sp.
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2023-01-24
err7
PREAI
errFu, Peinan; Zhang, Yang; Wang, Chenyin; Si, Shuyi; Liu, Xingzhong; Che, Yongsheng
err分享
err收藏
Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health基于益生元的纳米无定形阿托伐他汀通过恢复肠道和肝脏健康来减轻非酒精性脂肪性肝病
errSMALL STRUCTURES
IF11.3
err2023-01-18
err1
errOAAI
errCui, Jin-Jin; Li, Rui; Ma, Xiao-Lei; Yu, Hao-Yang; Luo, Zhi-Gang; Du, Peng; Ren, Ling; Ding, Xiao; Guo, Xiu-Ping; Zheng, Wen-Sheng; Jiang, Jian-Dong; Che, Yongsheng; Wang, Lu-Lu
err分享
err收藏
Cladoxanthones A and B, Xanthone-Derived Metabolites with a Spiro[cyclopentane-1,2′-[3,9a]ethanoxanthene]-2,4′,9′,11′-tetraone Skeleton from a Cladosporium sp.
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2022-11-11
err6
PREAI
errZhang, Yang; Fu, Peinan; Zhang, Yiqing; Xu, Yang; Zhang, Chunyan; Liu, Xingzhong; Che, Yongsheng
err分享
err收藏
Bicyclol Alleviates Atherosclerosis by Manipulating Gut Microbiota
errSMALL
IF12.1
err2022-01-27
err15
PREAI
errLi, Xiao-Lin; Cui, Jin-Jin; Zheng, Wen-Sheng; Zhang, Jin-Lan; Li, Rui; Ma, Xiao-Lei; Lin, Miao; Guo, Hui-Hui; Li, Cong; Yu, Xiao-You; Du, Peng; Zhao, Li-Min; He, Shuwang; Lan, Pei; Jiang, Jian-Dong; Che, Yongsheng; Wang, Lu-Lu
err分享
err收藏
Neopestolides A-D, Diphenyl Ether Derivatives from the Plant Endophytic Fungus Neopestalotiopsis sp.
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2022-01-20
err4
PREAI
errLi, Chuan; Xu, Yang; Fu, Peinan; Guo, Liangdong; Che, Yongsheng
err分享
err收藏
Overproduction of medicinal ergot alkaloids based on a fungal platform
errMETABOLIC ENGINEERING
IF6.8
err2022-01-01
err18
PREAI
errYao, Yongpeng; Wang, Wei; Shi, Wenyu; Yan, Rui; Zhang, Jun; Wei, Guangzheng; Liu, Ling; Che, Yongsheng; An, Chunyan; Gao, Shu-Shan
err分享
err收藏
Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients
errSignal Transduction and Targeted Therapy
IF52.7
err2021-12-06
err0
errOAAI
errJin-Lan Zhang; Yu-Huan Li; Lu-Lu Wang; Hong-Qi Liu; Shuai-Yao Lu; Yong Liu; Ke Li; Bin Liu; Su-Yun Li; Feng-Min Shao; Kun Wang; Ning Sheng; Rui Li; Jin-Jin Cui; Pei-Chun Sun; Chun-Xia Ma; Bo Zhu; Zhe Wang; Yuan-Hao Wan; Shi-Shan Yu; Yongsheng Che; Chao-Yang Wang; Chen Wang; Qiangqian Zhang; Li-Min Zhao; Xiao-Zhong Peng; Zhenshun Cheng; Jun-Biao Chang; Jian-Dong Jiang
err分享
err收藏
Repurposing carrimycin as an antiviral agent against human coronaviruses, including the currently pandemic SARS-CoV-2将carrimycin用作抗人类冠状病毒的抗病毒剂，包括目前大流行的SARS-CoV-2
errACTA PHARMACEUTICA SINICA B
IF14.6
err2021-09-01
err26
errOAAI
errYan, Haiyan; Sun, Jing; Wang, Kun; Wang, Huiqiang; Wu, Shuo; Bao, Linlin; He, Weiqing; Wang, Dong; Zhu, Airu; Zhang, Tian; Gao, Rongmei; Dong, Biao; Li, Jianrui; Yang, Lu; Zhong, Ming; Lv, Qi; Qin, Feifei; Zhuang, Zhen; Huang, Xiaofang; Yang, Xinyi; Li, Yuhuan; Che, Yongsheng; Jiang, Jiandong
err分享
err收藏
Characterization of a Prenyltransferase for Iso-A82775C Biosynthesis and Generation of New Congeners of Chloropestolides (vol 13, pg 703, 2018)
errACS CHEMICAL BIOLOGY
IF3.8
err2020-08-04
err0
PREAI
errPan, Yuanyuan; Liu, Ling; Guan, Feifei; Li, Erwei; Jin, Jin; Li, Jinyang; Che, Yongsheng; Liu, Gang
err分享
err收藏
Disulfide Cleavage in a Dimeric Epipolythiodioxopiperazine Natural Product Diminishes Its Apoptosis-Inducing Effect but Enhances Autophagy in Tumor Cells
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2020-01-16
err12
PREAI
errLi, Erwei; Hou, Bolin; Gao, Quan; Xu, Yang; Zhang, Caining; Liu, Xingzhong; Jiang, Xuejun; Che, Yongsheng
err分享
err收藏
Enzymatic Intermolecular Hetero-Diels-Alder Reaction in the Biosynthesis of Tropolonic Sesquiterpenes
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-08-28
err93
errOAAI
errChen, Qibin; Gao, Jie; Jamieson, Cooper; Liu, Jiawang; Ohashi, Masao; Bai, Jian; Yan, Daojian; Liu, Bingyu; Che, Yongsheng; Wang, Yanan; Houk, K. N.; Hu, Youcai
err分享
err收藏
Grb2 binds to PTEN and regulates its nuclear translocation to maintain the genomic stability in DNA damage response
errCELL DEATH & DISEASE
IF9.6
err2019-07-18
err28
errOAAI
errHou, Bolin; Xu, Shanshan; Xu, Yang; Gao, Quan; Zhang, Caining; Liu, Ling; Yang, Huaiyi; Jiang, Xuejun; Che, Yongsheng
err分享
err收藏

研究方向

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合作学者
合作期刊
A
Adrian L. Harris
H 指数: 187 · 论文数: 2.1K
管坤良 封面图
管坤良 (Kun‐Liang Guan)
H 指数: 168 · 论文数: 623
J
J. Wade Harper
H 指数: 141 · 论文数: 461
J
James E. Haber
H 指数: 124 · 论文数: 541
P
Patrizia Agostinis
H 指数: 99 · 论文数: 472
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