Stéphane de Botton - Publications, H-index & Citations

Stéphane de Botton

Institut Gustave Roussy

70H指数

470论文数

2.0W被引数

收录论文 103

发表时间

Real-world patterns of treatment intensity and prognostic model performance in older acute myeloid leukemia: insights from the French ALFA-PPP Cohort 老年急性髓系白血病患者治疗强度的真实世界模式与预后模型性能：来自法国ALFA-PPP队列的见解

Leukemia

IF13.4

2026-08-11

PREAI

Lin Pierre Zhao; Céline Berthon; Laurene Fenwarth; Stephane De Botton; Thomas Cluzeau; Laure Farnault; Sylvain Chantepie; Pierre Arnautou; Thorsten Braun; Mathieu Leclerc; Delphine Lebon; Ahmad Aljijakli; Isabelle Plantier; Ollivier Legrand; Juliette Lambert; Christophe Willekens; Emmanuel Raffoux; Claire Bories; Emilie Lemasle; Kevin-James Wattebled; Ambroise Marcais; Celia Salanoubat; Pascal Turlure; Jamile Frayfer; Benjamin Carpentier; Madalina Uzunov; Reda Garidi; Iona Vaida; Renaud Buffet; Alexandra Coelho; Karine Celli-Lebras; Raphael Itzykson; Claude Preudhomme; Nicolas Duployez; Hervé Dombret; Lionel Adès

Genomic landscape of acute myeloid leukemia in adolescents and young adults 青少年和年轻成人急性髓系白血病的基因组景观

Leukemia

IF13.4

2026-06-25

PREAI

Loïc Vasseur; Nicolas Duployez; Jérôme Lambert; Hélène Lapillonne; Stéphane De Botton; Alice Marceau-Renaut; Etienne Lengliné; Christian Récher; Marion Strullu; Paul Saultier; Eric Jourdan; Claude Gardin; Marie Balsat; Pascale Cornillet-Lefebvre; Dominique Penther; Isabelle Luquet; Wendy Cuccuini; Guy Leverger; Arnaud Petit; Claude Preudhomme; Nicolas Boissel; Laurène Fenwarth

Comprehensive mutational profiling and clinical outcome of adult acute myeloid leukemia patients with NUP98 rearrangement NUP98重排的成人急性髓系白血病患者的综合突变谱和临床结局

Leukemia

IF13.4

2026-05-12

PREAI

Benoit Ducourneau; Arnaud Pages; Stéphanie Struski; Matthieu Decamp; Emmanuel Raffoux; Céline Berthon; Laurène Fenwarth; Vincent Marmouset; Cécile Pautas; Thomas Cluzeau; Delphine Lebon; Madalina Uzunov; Patricio Pereyra; Maël Heiblig; Jean-Valère Malfuson; Laure Farnault; Pierre-Yves Dumas; Julia Hieulle; Sarah Bertoli; Sylvain Chantepie; Nathalie Auger; Audrey Bidet; Marie-Joelle Mozziconacci; Augustin Boudry; Isabelle Luquet; Laureen Chat; Romain Loyaux; Lina El-Mur; Emmanuelle Clappier; Claude Gardin; Mathilde Hunault; Stéphane De Botton; Arnaud Pigneux; Dominique Penther; Eric Delabesse; Raphael Itzykson; Claude Preudhomme; Hervé Dombret; Christian Recher; Nicolas Duployez; Jean-Baptiste Micol

Oral azacitidine maintenance therapy for patients with acute myeloid leukaemia and myelodysplasia-related changes: Post hoc analysis of the QUAZAR AML-001 trial 口服阿扎胞苷维持治疗用于伴有骨髓增生异常相关改变的患者急性髓系白血病：QUAZAR AML-001试验的事后分析

British Journal of Haematology

IF3.8

2025-12-12

PREAI

Maria Teresa Voso; Stéphane de Botton; Michael Pfeilstöcker; Angela Figuera Alvarez; Kefeng Wang; Wendy L. See; Manuel Ugidos Guerrero; Daniel Lopes de Menezes; Erica Petrlik; Thomas Prebet; Gail J. Roboz

Olutasidenib for mutated IDH1 acute myeloid leukemia: final five-year results from the phase 2 pivotal cohort Olutasidenib治疗IDH1突变急性髓系白血病: 2期关键队列的最终五年结果

Journal of Hematology & Oncology

IF40.4

2025-11-17

OAAI

Jorge Cortes; Antonio Curti; Pierre Fenaux; Brian A. Jonas; Jürgen Krauter; Pau Montesinos; Christian Récher; David C. Taussig; Eunice S. Wang; Justin Watts; Andrew Wei; Karen WL Yee; Hua Tian; Aaron Sheppard; Christophe Marzac; Stephane de Botton

BULLETIN DU CANCER

IF0.8

2025-11-01

PREAI

El Murr, Lina; Saleh, Khalil; Pasquier, Florence; Willekens, Christophe; Danu, Alina; Pilorge, Sylvain; Auger, Nathalie; Sada, Veronique; Delaloge, Suzette; De Botton, Stephane; Pages, Arnaud; Micol, Jean-Baptiste

CAR T cell–mediated bone marrow inflammation causes hematotoxicity and favors clonal hematopoiesis CAR T细胞介导的骨髓炎症导致造血毒性并促进克隆性造血

Science Translational Medicine

IF14.6

2025-09-24

PREAI

Myriam Ben Khelil; Ahmadreza Arbab; Janesa Srikanthan; Laura Marcos Kovandzic; Véronique Vergé; Arnaud Pagès; Jessica Rengassamy; Roula Amine-Hneineh; Marine Aglave; Rémy Jelin; Vincent Ribrag; Wassila Rahali; Paul-Auguste Goutebroze; Stéphane de Botton; Laurie Menger; Ileana Antony-Debré; Jean-Baptiste Micol; Christophe Marzac; Cristina Castilla Llorente; Camille Bigenwald

Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia 靶向凋亡的BH3拟似物：改变急性髓系白血病患者的治疗方法

Nature Reviews Clinical Oncology

IF82.2

2025-09-01

PREAI

Antonino Glaviano; Ellen Weisberg; Hiu Y. Lam; Donavan J. J. Tan; Andrew J. Innes; Yubin Ge; Catherine E. Lai; Wendy Stock; Christina Glytsou; Linda Smit; Tatsushi Yoshida; Tian Y. Zhang; Vanessa E. Kennedy; B. Douglas Smith; Thomas Mercher; Stéphane de Botton; Patrizia Diana; Marina Konopleva; Michael J. Mauro; James D. Griffin; Courtney D. DiNardo; Alan P. Kumar

Long-term results from the AGILE study of azacitidine plus ivosidenib vs placebo in newly diagnosed IDH1-mutated AML AGILE研究中，阿扎胞苷联合伊沃西登ib与安慰剂在 Newly Diagnosed IDH1-mutated AML中的长期结果

Blood Advances

IF7.1

2025-07-28

OAAI

Pau Montesinos; Dylan M. Marchione; Christian Recher; Michael Heuser; Susana Vives; Ewa Zarzycka; Jianxiang Wang; Marta Riva; Rodrigo T. Calado; Andre C. Schuh; Su-Peng Yeh; Adriana E. Tron; Jianan Hui; Diego A. Gianolio; Sung Choe; Prapti Patel; Stéphane De Botton; Courtney D. DiNardo; Hartmut Döhner

Pivotal results of SELECT-MDS-1 phase 3 study of tamibarotene with azacitidine in newly diagnosed higher-risk MDS 他米巴罗替与阿扎胞苷联合治疗新诊断高危骨髓增生异常综合征（MDS）的SELECT-MDS-1三期研究的关键结果

Blood Advances

IF7.1

2025-05-09

OAAI

Amy E. DeZern; Sylvain Thepot; Stephane de Botton; Andrea Patriarca; Dries Deeren; Jose-Miguel Torregrossa-Diaz; Giovanni Marconi; Teresa Bernal; Juan Bergua Burgues; Blanca Xicoy; Anna Jonášová; Amer M. Zeidan; Sophie Dimicoli-Salazar; Célestine Simand; David Valcarcel; Maria Diez Campelo; Wanxing Chai-Ho; Lalit Saini; Alice Garnier; Klaus Geissler; Yishai Ofran; Zsolt Nagy; Pramila Krishnamurthy; Michael Lübbert; Grzegorz Basak; Hetty E. Carraway; David A. Sallman; Uma Borate; Valeria Santini; Victoria Campbell; Pierre Fenaux; Thorsten Braun; Francesco Lanza; Jan Maciej Zaucha; David A. Roth; Sofia Paul; Pourab Roy; Michael J. Kelly; Angela Volkert; Jaime Chisholm; Tanya Abdul Malak; Virginia M. Klimek; Thomas Cluzeau

AUTX703, a Novel and Potent KAT2A and KAT2B Protein Degrader, Induces Differentiation and Offers Survival Advantage in a Primary Human AML Xenograft Model AUTX703，一种新型的强效KAT2A和KAT2B蛋白质降解剂，可诱导分化，并在原代人AML异种移植模型中提供生存优势。

BLOOD

IF23.1

2024-11-05

PREAI

Duparc, Helene; Neef, James; Kandiah, Janany; Bhatta, Maulasri; Chedeville, Agathe; Debartolo, Joe; Sinicropi-Yao, Sara; Chan, Betty; Constan, Alex; Marzac, Christophe; Micol, Jean-Baptiste; Antipov, Laura; De Botton, Stephane; Yen, Katharine E.; Millan, David S.; Antony-Debre, Ileana; Straley, Kimberly S.

IL-1RAP Is a Targetable Surface Antigen in Relapsed/Refractoy AML IL-1RAP 是复发性/难治性 AML 中一个可靶向的表面抗原

BLOOD

IF23.1

2024-11-05

PREAI

Sabbah, Mohamad; Fontaine, Morgane; Pacchiardi, Kim; Delabriere, Alexis; De Botton, Stephane; Lonchamp, Catherine; Buffet, Renaud; Farnault, Laure; Micol, Jean-Baptiste; Dumas-Rivero, Typhaine; Raffoux, Emmanuel; Ades, Lionel; Boissel, Nicolas; Lambert, Juliette; Wattebled, Kevin-James; Duchmann, Matthieu; Celli-Lebras, Karine; Coelho, Alexandra; Dombret, Herve; De Dreuzy, Edouard; Deschamps, Marina; Ferrand, Christophe; Hasskarl, Jens; Sainson, Richard; Itzykson, Raphael

Final phase 1 substudy results of ivosidenib for patients with mutant IDH1 relapsed/refractory myelodysplastic syndrome ivosidenib治疗突变型IDH1复发/难治性骨髓增生异常综合征患者的最终1期亚研究结果

BLOOD ADVANCES

IF7.1

2024-08-13

OAAI

DiNardo, Courtney D.; Roboz, Gail J.; Watts, Justin M.; Madanat, Yazan F.; Prince, Gabrielle T.; Baratam, Praneeth; de Botton, Stphane; Stein, Anthony; Foran, James M.; Arellano, Martha L.; Sallman, David A.; Hossain, Mohammad; Marchione, Dylan M.; Bai, Xiaofei; Patel, Prapti A.; Kapsalis, Stephanie M.; Garcia-Manero, Guillermo; Fathi, Amir T.

Potent and selective degradation of KAT2A and KAT2B induces profound cell state changes and inhibits growth of AML, SCLC and NEPC model systems

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Straley, Kimberly S.; Neef, James; Antony-Debre, Ileana; Bhatta, Maulasri; Sharma, Sambad; Sinicropi-Yao, Sara; DeBartolo, Joe; McRiner, Andrew; Chan, Betty; Wilson, Henry; Lee, Christina S.; Boudhraa, Zied; El Ezzy, Mohamed; Sharif, Umar; Bittinger, Mark; Antipov, Laura; Graeber, Thomas G.; de Botton, Stephane; Yen, Katharine E.; Millan, David S.

Pharmacodynamics and antitumor mechanism of the BRG1/BRM (SMARCA4/2) inhibitor FHD-286 in a Phase 1 study in subjects with AML or MDS

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-01

PREAI

Collins, Mike; Thomsen, Astrid; Elliott, GiNell; Wan, Jessica; Horrigan, Kim; Delestre, Laure; Penard-Lacronique, Virginie; De Botton, Stephane; Fiskus, Warren; Bhalla, Kapil N.; DiNardo, Courtney; Agresta, Samuel; Piel, Jessica; Hentemann, Martin

CAR T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia CAR T细胞治疗b细胞急性淋巴细胞白血病

JOURNAL OF CLINICAL MEDICINE

IF2.9

2023-10-31

OAAI

Saleh, Khalil; Pasquier, Florence; Bigenwald, Camille; De Botton, Stephane; Ribrag, Vincent; Castilla-Llorente, Cristina

Standardising acute myeloid leukaemia classification systems: a perspective from a panel of international experts

LANCET HAEMATOLOGY

IF17.7

2023-09-01

PREAI

Shallis, Rory M.; Daver, Naval; Altman, Jessica K.; Komrokji, Rami S.; Pollyea, Daniel A.; Badar, Talha; Bewersdorf, Jan P.; Bhatt, Vijaya R.; de Botton, Stephane; Burguera, Adolfo de la Fuente; Carraway, Hetty E.; Desai, Pinkal; Dillon, Richard; Duployez, Nicolas; El Chaer, Firas; Fathi, Amir T.; Freeman, Sylvie D.; Gojo, Ivana; Grunwald, Michael R.; Jonas, Brian A.; Konopleva, Marina; Lin, Tara L.; Mannis, Gabriel N.; Mascarenhas, John; Michaelis, Laura C.; Mims, Alice S.; Montesinos, Pau; Pozdnyakova, Olga; Pratz, Keith W.; Schuh, Andre C.; Sekeres, Mikkael A.; Smith, Catherine C.; Stahl, Maximilian; Subklewe, Marion; Uy, Geoffrey L.; Voso, Maria Teresa; Walter, Roland B.; Wang, Eunice S.; Fzeidner, Joshua F.; Zucenka, Andrius; Zeidan, Amer M.

LSC17 score complements genetics and measurable residual disease in acute myeloid leukemia: an ALFA study

BLOOD ADVANCES

IF7.1

2023-07-28

OAAI

Vasseur, Loic; Fenwarth, Laurene; Lambert, Jerome; de Botton, Stephane; Figeac, Martin; Villenet, Celine; Heiblig, Mael; Dumas, Pierre-Yves; Recher, Christian; Berthon, Celine; Lemasle, Emilie; Lebon, Delphine; Lambert, Juliette; Terre, Christine; Celli-Lebras, Karine; Dombret, Herve; Preudhomme, Claude; Cheok, Meyling; Itzykson, Raphael; Duployez, Nicolas

Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed or refractory IDH1-mutated AML Olutasidenib (FT-2102) 可诱导复发或难治性IDH1-mutated AML患者持久完全缓解

BLOOD ADVANCES

IF7.1

2023-06-30

OAAI

de Botton, Stephane; Fenaux, Pierre; Yee, Karen; Recher, Christian; Wei, Andrew H.; Montesinos, Pau; Taussig, David C.; Pigneux, Arnaud; Braun, Thorsten; Curti, Antonio; Grove, Carolyn; Jonas, Brian A.; Khwaja, Asim; Legrand, Ollivier; Peterlin, Pierre; Arnan, Montserrat; Blum, William; Cilloni, Daniela; Hiwase, Devendra K.; Jurcic, Joseph G.; Krauter, Juergen; Thomas, Xavier; Watts, Justin M.; Yang, Jay; Polyanskaya, Olga; Brevard, Julie; Sweeney, Jennifer; Barrett, Emma; Cortes, Jorge

Safety, efficacy, and PK/PD of vorasidenib in previously treated patients with mIDH1/2 hematologic malignancies: A phase 1 study

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2023-06-24

OAAI

DiNardo, Courtney D.; De Botton, Stephane; Pollyea, Daniel A.; Stone, Richard M.; Altman, Jessica K.; Fathi, Amir T.; Limsakun, Tharin; Liang, Min; Choe, Sung; Hossain, Mohammad; Tron, Adriana E.; Meng, Qian; Kapsalis, Stephanie M.; Pandya, Shuchi S.; Stein, Eytan M.

研究方向