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Deep immune profiling of intrahepatic cholangiocarcinoma with CODEX multiplexed imaging 使用CODEX多重成像对肝内胆管癌进行深度免疫分析 Baretti, Marina; Shekhar, Soumya; Sahai, Vaibhav; Shu, Daniel; Howe, Kathryn; Gunchick, Valerie; Assarzadegan, Naziheh; Kartalia, Emma; Zhu, Qingfeng; Hallab, Elsa; Sheth-Shah, Archit; Kondo, Aya; Azad, Nilofer S.; Yarchoan, Mark 分享 收藏
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CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial CD137激动作用增强了新辅助性胰腺癌临床试验中抗PD-1诱导的扩增CD8+ T细胞克隆的激活。 Montagne, Janelle M.; Mitchell, Jacob T.; Tandurella, Joseph A.; Christenson, Eric S.; Danilova, Ludmila, V; Deshpande, Atul; Loth, Melanie; Sidiropoulos, Dimitrios N.; Davis-Marcisak, Emily; Bergman, Daniel R.; Zhu, Qingfeng; Wang, Hao; Kagohara, Luciane T.; Engle, Logan L.; Green, Benjamin F.; Favorov, Alexander, V; Ho, Won Jin; Lim, Su Jin; Zhang, Rui; Li, Pan; Gai, Jessica; Mo, Guanglan; Mitchell, Sarah; Wang, Rulin; Vaghasia, Ajay; Hou, Wenpin; Xu, Yao; Zimmerman, Jacquelyn W.; Elisseeff, Jennifer H.; Yegnasubramanian, Srinivasan; Anders, Robert A.; Jaffee, Elizabeth M.; Zheng, Lei; Fertig, Elana J. 分享 收藏
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma Shu, Daniel H.; Ho, Won Jin; Kagohara, Luciane T.; Girgis, Alexander; Shin, Sarah M.; Danilova, Ludmila; Lee, Jae W.; Sidiropoulos, Dimitrios N.; Mitchell, Sarah; Munjal, Kabeer; Howe, Kathryn; Bendinelli, Kayla J.; Kartalia, Emma; Qi, Hanfei; Mo, Guanglan; Montagne, Janelle; Leatherman, James M.; Lopez-Vidal, Tamara Y.; Zhu, Qingfeng; Huff, Amanda L.; Yuan, Xuan; Hernandez, Alexei; Coyne, Erin M.; Zaidi, Neeha; Zabransky, Daniel J.; Engle, Logan L.; Ogurtsova, Aleksandra; Baretti, Marina; Laheru, Daniel; Durham, Jennifer N.; Wang, Hao; Sunshine, Joel C.; Johnston, Robert J.; Deutsch, Julie Stein; Taube, Janis M.; Anders, Robert A.; Jaffee, Elizabeth M.; Fertig, Elana J.; Yarchoan, Mark 分享 收藏
Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery Zhang, Shuming; Deshpande, Atul; Verma, Babita K.; Wang, Hanwen; Mi, Haoyang; Yuan, Long; Ho, Won Jin; Jaffee, Elizabeth M.; Zhu, Qingfeng; Anders, Robert A.; Yarchoan, Mark; Kagohara, Luciane T.; Fertig, Elana J.; Popel, Aleksander S. 分享 收藏
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Machine learning integrating spatial omics uncovers humoral immunity patterns in intratumoral tertiary lymphoid structures in pancreatic cancer pathologic responders Sidiropoulos, Dimitrios N.; Shin, Sarah M.; Girgis, Alexander; Shu, Daniel H.; Montagne, Janelle; Deshpande, Atul; Johnson, Jeanette A.; Dequiedt, Lucie; Jacobs, Victoria; Ogurtsova, Aleksandra; Mo, Guanglan; Yuan, Xuan; Stein-O'Brien, Genevieve; Yarchoan, Mark; Zhu, Qingfeng; Kiemen, Ashley; Jaffee, Elizabeth M.; Zheng, Lei; Ho, Won Jin; Anders, Robert; Fertig, Elana J.; Kagohara, Luciane T. 分享 收藏
Identification of a novel morphology of tertiary lymphoid structure in patients with hepatocellular carcinoma treated with neoadjuvant immune checkpoint blockade Shu, Daniel H.; Ho, Won Jin; Kagohara, Luciane T.; Girgis, Alexander; Shin, Sarah M.; Danilova, Ludmila; Lee, Jae W.; Sidiropoulos, Dimitrios N. N.; Mitchell, Sarah; Munjal, Kabeer; Howe, Kathryn; Bendinelli, Kayla J.; Qi, Hanfei; Mo, Guanglan; Montagne, Janelle; Lopez-Vidal, Tamara Y.; Zhu, Qingfeng; Huff, Amanda L.; Yuan, Xuan; Hernandez, Alexei; Coyne, Erin M.; Zaidi, Neeha; Zabransky, Daniel J.; Engle, Logan L.; Ogurtsova, Aleksandra; Baretti, Marina; Laheru, Daniel; Durham, Jennifer N.; Wang, Hao; Anders, Robert; Jaffee, Elizabeth M.; Fertig, Elana J.; Yarchoan, Mark 分享 收藏
Integrating spatial multi-omics data with spatial quantitative pharmacology (spQSP) model to simulate human neoadjuvant immunotherapy clinical trial of hepatocellular carcinoma Zhang, Shuming; Deshpande, Atul; Verma, Babita K.; Wang, Hanwen; Mi, Haoyang; Yuan, Long; Ho, Won Jin; Jaffee, Elizabeth M.; Zhu, Qingfeng; Anders, Robert A.; Yarchoan, Mark; Kagohara, Luciane T.; Fertig, Elana J.; Popel, Aleksander S. 分享 收藏
Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade Chen, Shuming; McMiller, Tracee L.; Soni, Abha; Succaria, Farah; Sidhom, John-William; Cappelli, Laura C.; Casciola-Rosen, Livia A.; Morales, Isaac R.; Sankaran, Preethi; Berger, Alan E.; Deutsch, Julie Stein; Zhu, Qingfeng C.; Anders, Robert A.; Hooper, Jody E.; Pardoll, Drew M.; Lipson, Evan J.; Taube, Janis M.; Topalian, Suzanne L. 分享 收藏
Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial 恩替诺特、nivolumab和ipilimumab治疗晚期HER2-negative乳腺癌的Ib期临床试验 Torres, Evanthia. T. Roussos; Ho, Won J.; Danilova, Ludmila; Tandurella, Joseph A.; Leatherman, James; Rafie, Christine; Wang, Chenguang; Brufsky, Adam; LoRusso, Patricia; Chung, Vincent; Yuan, Yuan; Downs, Melinda; OConnor, Ashley; Shin, Sarah M.; Hernandez, Alexei; Engle, Elizabeth L.; Piekarz, Richard; Streicher, Howard; Talebi, Zahra; Rudek, Michelle A.; Zhu, Qingfeng; Anders, Robert A.; Cimino-Mathews, Ashley; Fertig, Elana J.; Jaffee, Elizabeth M.; Stearns, Vered; Connolly, Roisin M. 分享 收藏
Neoadjuvant radioimmunotherapy in pancreatic cancer enhances effector T cell infiltration and shortens their distances to tumor cells Wang, Junke; Gai, Jessica; Zhang, Tengyi; Niu, Nan; Qi, Hanfei; Thomas, Dwayne L.; Li, Keyu; Xia, Tao; Rodriguez, Christina; Parkinson, Rose; Durham, Jennifer; Mcphaul, Thomas; Narang, Amol K.; Anders, Robert A.; Osipov, Arsen; Wang, Hao; He, Jin; Laheru, Daniel A.; Herman, Joseph M.; Lee, Valerie; Jaffee, Elizabeth M.; Thompson, Elizabeth D.; Zhu, Qingfeng; Zheng, Lei 分享 收藏
Science with the 2.5-meter Wide Field Survey Telescope (WFST) Wang, Tinggui; Liu, Guilin; Cai, Zhenyi; Geng, Jinjun; Fang, Min; He, Haoning; Jiang, Ji-an; Jiang, Ning; Kong, Xu; Li, Bin; Li, Ye; Luo, Wentao; Pan, Zhizheng; Wu, Xuefeng; Yang, Ji; Yu, Jiming; Zheng, Xianzhong; Zhu, Qingfeng; Cai, Yi-Fu; Chen, Yuanyuan; Chen, Zhiwei; Dai, Zigao; Fan, Lulu; Fan, Yizhong; Fang, Wenjuan; He, Zhicheng; Hu, Lei; Hu, Maokai; Jin, Zhiping; Jiang, Zhibo; Li, Guoliang; Li, Fan; Li, Xuzhi; Liang, Runduo; Lin, Zheyu; Liu, Qingzhong; Liu, Wenhao; Liu, Zhengyan; Liu, Wei; Liu, Yao; Lou, Zheng; Qu, Han; Sheng, Zhenfeng; Shi, Jianchun; Shu, Yiping; Su, Zhenbo; Sun, Tianrui; Wang, Hongchi; Wang, Huiyuan; Wang, Jian; Wang, Junxian; Wei, Daming; Wei, Junjie; Xue, Yongquan; Yan, Jingzhi; Yang, Chao; Yuan, Ye; Yuan, Yefei; Zhang, Hongxin; Zhang, Miaomiao; Zhao, Haibin; Zhao, Wen 分享 收藏
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces (vol 14, pg 285, 2023) Deshpande, Atul; Loth, Melanie; Sidiropoulos, Dimitrios N.; Zhang, Shuming; Yuan, Long; Bell, Alexander T. F.; Zhu, Qingfeng; Ho, Won Jin; Santa-Maria, Cesar; Gilkes, Daniele M.; Williams, Stephen R.; Uytingco, Cedric R.; Chew, Jennifer; Hartnett, Andrej; Bent, Zachary W.; V. Favorov, Alexander; Popel, Aleksander S.; Yarchoan, Mark; Kiemen, Ashley; Wu, Pei-Hsun; Fujikura, Kohei; Wirtz, Denis; Wood, Laura D.; Zheng, Lei; Jaffee, Elizabeth M.; Anders, Robert A.; Danilova, Ludmila; Stein-O'Brien, Genevieve; Kagohara, Luciane T.; Fertig, Elana J. 分享 收藏
A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma 可切除胰腺腺癌患者新辅助和辅助抗肿瘤疫苗单独或联合PD-1拮抗剂和CD137激动剂抗体的平台试验 Heumann, Thatcher; Judkins, Carol; Li, Keyu; Lim, Su Jin; Hoare, Jessica; Parkinson, Rose; Cao, Haihui; Zhang, Tengyi; Gai, Jessica; Celiker, Betul; Zhu, Qingfeng; McPhaul, Thomas; Durham, Jennifer; Purtell, Katrina; Klein, Rachel; Laheru, Daniel; De Jesus-Acosta, Ana; Le, Dung T.; Narang, Amol; Anders, Robert; Burkhart, Richard; Burns, William; Soares, Kevin; Wolfgang, Christopher; Thompson, Elizabeth; Jaffee, Elizabeth; Wang, Hao; He, Jin; Zheng, Lei 分享 收藏
Single-cell RNA and TCR sequencing of tumor infiltrating lymphocytes identifies changes in pancreatic ductal adenocarcinomas following neoadjuvant treatment with combined anti-PD-1 blocking and anti-CD137 agonist therapy Tandurella, Joseph A.; Mitchell, Jacob T.; Montagne, Janelle M.; Christenson, Eric; Zhu, Qingfeng; Danilova, Ludmilla V.; Favorov, Alexander V.; Ho, Won J.; Kagohara, Luciane T.; Loth, Melanie; Lim, Su Jin; Zheng, Rui; Gai, Jessica; Mitchell, Sarah; Sidiropoulos, Dimitrios N.; Hou, Wenpin; Xu, Yao; Wang, Hao; Zimmerman, Jacquelyn W.; Yegnasubramanian, Srinivasan; Anders, Robert; Jaffee, Elizabeth M.; Zheng, Lei; Fertig, Elana J. 分享 收藏
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces Deshpande, Atul; Loth, Melanie; Sidiropoulos, Dimitrios N.; Zhang, Shuming; Yuan, Long; Bell, Alexander T. F.; Zhu, Qingfeng; Ho, Won Jin; Santa-Maria, Cesar; Gilkes, Daniele M.; Williams, Stephen R.; Uytingco, Cedric R.; Chew, Jennifer; Hartnett, Andrej; Bent, Zachary W.; Favorov, Alexander V.; Popel, Aleksander S.; Yarchoan, Mark; Kiemen, Ashley; Wu, Pei-Hsun; Fujikura, Kohei; Wirtz, Denis; Wood, Laura D.; Zheng, Lei; Jaffee, Elizabeth M.; Anders, Robert A.; Danilova, Ludmila; Stein-O'Brien, Genevieve; Kagohara, Luciane T.; Fertig, Elana J. 分享 收藏
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