Eric Gouaux - Publications, H-index & Citations

Eric Gouaux

oregon health and science university

85H指数

1.2K论文数

3.0W被引数

收录论文 54

发表时间

Structural and mechanistic insights into gating and allosteric modulation of GluN1–GluN3A NMDA receptors GluN1–GluN3A NMDA受体门控和别构调控的结构与机制见解

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-08-28

OAAI

Junhoe Kim; Avery J. Benton; James S. Lotti; Nirvan Rouzbeh; Kasper B. Hansen; Eric Gouaux

Native AMPA receptor architecture reveals SynDIG4 engagement and auxiliary subunit heterogeneity 原生AMPA受体结构揭示了SynDIG4的参与和辅助亚基异质性

Science Advances

IF12.5

2026-06-12

OAAI

Chengli Fang; Eric Gouaux

Tetrazine Functionalized Graphene Enables Capture of Ultra-Low Concentrations of Biomacromolecules 四嗪功能化石墨烯能够捕获超低浓度的生物大分子

Small

IF12.1

2026-03-25

OAAI

Ravindra K. Gupta; Hanbin Jeong; April Goehring; Eric Gouaux; Maggie He

The protocadherin 15 – LHFPL5 tip link complex is a heterotetrameric assembly in hair cell stereocilia 原钙粘蛋白15 – LHFPL5顶连蛋白复合体是毛细胞静纤毛中的异四聚体组装结构。

Biophysical Journal

IF3.1

2026-02-10

PREAI

Sarah Clark; Jaba Mitra; Johannes Elferich; April Goehring; Jingpeng Ge; Taekjip Ha; Eric Gouaux

Efficient and rapid isolation of native AMPA receptor complexes for cryo-EM 高效快速隔离天然AMPA受体复合物用于冷冻EM

Protein Science

IF5.2

2026-01-24

OAAI

Jumi Park; Eric Gouaux

Cryo-EM of autoantibody-bound NMDA receptors reveals antigenic hotspots in an active immunization model of anti-NMDAR encephalitis 抗NMDAR脑炎主动免疫模型中，冷冻电镜观察到的自身抗体结合NMDA受体揭示了抗原性热点区域

Science Advances

IF12.5

2026-01-14

PREAI

Kim, Junhoe; Jalali-Yazdi, Farzad; Jones, Brian E.; Westbrook, Gary L.; Gouaux, Eric

Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements NMDA受体激活的冷冻电镜快照阐明了顺序重排

Science Advances

IF12.5

2025-09-24

PREAI

Jamie A. Abbott; Junhoe Kim; Beiying Liu; Gabriela K. Popescu; Eric Gouaux; Farzad Jalali-Yazdi

Accelerating Outreach and Training at the Pacific Northwest CryoEM Center Through Advanced Sample Preparation with the Vitrojet

Microscopy and Microanalysis

IF3

2025-07-25

OAAI

Omar Davulcu; Marcelo de Farias; Rose Marie Haynes; Nancy Meyer; Marzia Miletto; Sean Mulligan; Janette Myers; Vamseedhar Rayaprolu; Kjirsten Wheeler; James E Evans; Eric Gouaux; Steve Reichow; Claudia S López; Craig Yoshioka

The bile acid-sensitive ion channel is gated by Ca2+-dependent conformational changes in the transmembrane domain 胆汁酸敏感性离子通道由跨膜结构域中的Ca2+依赖性构象变化调控。

Nature Communications

IF15.7

2025-07-22

OAAI

Makayla M. Freitas; Eric Gouaux

Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses 天然海马谷氨酸能突触的冷冻电子断层扫描研究

ELIFE

IF0

2024-11-04

OAAI

Matsui, Aya; Spangler, Cathy; Elferich, Johannes; Shiozaki, Momoko; Jean, Nikki; Zhao, Xiaowei; Qin, Maozhen; Zhong, Haining; Yu, Zhiheng; Gouaux, Eric

The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid- mediated subunit contacts in mechanosensory transduction

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-02-14

OAAI

Clark, Sarah; Jeong, Hanbin; Posert, Rich; Goehring, April; Gouaux, Eric

Large-scale growth of C. elegans and isolation of membrane protein complexes

NATURE PROTOCOLS

IF16

2023-07-26

PREAI

Clark, Sarah; Jeong, Hanbin; Goehring, April; Kang, Yunsik; Gouaux, Eric

Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-12

OAAI

Yang, Dongxue; Zhao, Zhiyu; Tajkhorshid, Emad; Gouaux, Eric

Quantitative DNA-PAINT imaging of AMPA receptors in live neurons

CELL REPORTS METHODS

IF4.5

2023-02-01

OAAI

Youn, Yeoan; Lau, Gloria W.; Lee, Yongjae; Maity, Barun Kumar; Gouaux, Eric; Chung, Hee Jung; Selvin, Paul R.

Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor

ELIFE

IF0

2022-08-17

OAAI

Ivica, Josip; Zhu, Hongtao; Lape, Remigijus; Gouaux, Eric; Sivilotti, Lucia G.

Illumination of serotonin transporter mechanism and role of the allosteric site

SCIENCE ADVANCES

IF12.5

2021-12-03

OAAI

Yang, Dongxue; Gouaux, Eric

The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter

NATURE COMMUNICATIONS

IF15.7

2021-08-20

OAAI

Plenge, Per; Yang, Dongxue; Salomon, Kristine; Laursen, Louise; Kalenderoglou, Iris E.; Newman, Amy H.; Gouaux, Eric; Coleman, Jonathan A.; Loland, Claus J.

Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding 5-羟色胺转运蛋白的细胞外环充当药物结合的选择性过滤器

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-07-01

OAAI

Esendir, Eray; Burtscher, Verena; Coleman, Jonathan A.; Zhu, Rong; Gouaux, Eric; Freissmuth, Michael; Sandtner, Walter

The intracellular domain of homomeric glycine receptors modulates agonist efficacy

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Ivica, Josip; Lape, Remigijus; Jazbec, Vid; Yu, Jie; Zhu, Hongtao; Gouaux, Eric; Gold, Matthew G.; Sivilotti, Lucia G.