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Karen Horsburgh

University of Edinburgh

H指数:46

被引数:6,247

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Col4a1 mutation in a mouse model of cerebral small vessel disease causes white matter defects that can be modulated by targeting protein folding

小鼠脑小血管病模型中的Col4a1基因突变导致白质缺陷，该缺陷可通过靶向蛋白质折叠进行调控

IF4.8

2026-08-010

PRE

Systematic review and meta-analysis of cognitive assessments used to detect deficits in the bilateral carotid artery stenosis model for vascular cognitive impairment

journal of cerebral blood flow and metabolism

IF0

2026-01-170

PRE

Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity

IF6.9

2024-05-011

OA

Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer's disease and experimental chronic cerebral hypoperfusion

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-02-154

OA

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

STEM CELL REPORTS

IF5.1

2023-12-018

OAAI

Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment

IF5.1

2023-11-015

OAAI

Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke

BRAIN PATHOLOGY

IF6.2

2022-06-246

OAAI

Impaired Glymphatic Function and Pulsation Alterations in a Mouse Model of Vascular Cognitive Impairment

血管性认知障碍小鼠模型的淋巴功能受损和搏动改变

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2022-01-1323

OAAI

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2021-03-1719

OAAI

Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment

JOURNAL OF NEUROINFLAMMATION

IF10.1

2020-12-0137

OAAI

Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment

实验性颈动脉狭窄对海马梗死病理，神经元和神经胶质的长期影响以及环境富集的改善作用

BRAIN RESEARCH BULLETIN

IF3.7

2020-10-0110

OAAI

Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction

BRAIN PATHOLOGY

IF6.2

2019-08-1637

OAAI

Carotid artery disease in post-stroke survivors and effects of enriched environment on stroke pathology in a mouse model of carotid artery stenosis

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

IF3.4

2019-05-2319

OAAI

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

HUMAN MOLECULAR GENETICS

IF3.2

2018-10-2222

OAAI

Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

SCIENTIFIC REPORTS

IF3.9

2018-08-2233

OAAI

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology

小血管，痴呆和慢性疾病-分子机制和病理生理学

CLINICAL SCIENCE

IF7.7

2018-04-3049

OAAI

Horsburgh, Karen; Wardlaw, Joanna M.; van Agtmael, Tom; Allan, Stuart M.; Ashford, Mike L. J.; Bath, Philip M.; Brown, Rosalind; Berwick, Jason; Cader, M. Zameel; Carare, Roxana O.; Davis, John B.; Duncombe, Jessica; Farr, Tracy D.; Fowler, Jill H.; Goense, Jozien; Granata, Alessandra; Hall, Catherine N.; Hainsworth, Atticus H.; Harvey, Adam; Hawkes, Cheryl A.; Joutel, Anne; Kalaria, Rajesh N.; Kehoe, Patrick G.; Lawrence, Catherine B.; Lockhart, Andy; Love, Seth; Macleod, Malcolm R.; Macrae, I. Mhairi; Markus, Hugh S.; McCabe, Chris; McColl, Barry W.; Meakin, Paul J.; Miller, Alyson; Nedergaard, Maiken; O'Sullivan, Michael; Quinn, Terry J.; Rajani, Rikesh; Saksida, Lisa M.; Smith, Colin; Smith, Kenneth J.; Touyz, Rhian M.; Trueman, Rebecca C.; Wang, Tao; Williams, Anna; Williams, Steven C. R.; Work, Lorraine M.

Cilostazol reduced gliovascular damage and working memory impairment via endotelial protection in a mouse model of vascular dementia

JOURNAL OF THE NEUROLOGICAL SCIENCES

IF3.2

2017-10-010

PREAI

Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

CLINICAL SCIENCE

IF7.7

2017-09-28294

OAAI

Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice

CLINICAL SCIENCE

IF7.7

2017-07-2432

OAAI

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

IF5.1

2017-07-1942

OAAI