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A

Angela Gritti

San Raffaele Telethon Institute for Gene Therapy
H指数:40
被引数:1.1万

个人简介

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工作经历

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荣誉奖项

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Targeting white matter astrocytes with a Gfap-disruptive Cas9 nuclease benefits a murine model of Alexander disease

靶向白质星形胶质细胞，使用Gfap干扰性Cas9核酸酶对亚历山大病小鼠模型有益

Molecular Therapy
IF12
2026-09-190
OAAI
Anne E.J. Hillen; Irene Capuano; Barbara Gega; Rossana Norata; Margaux Mombled; Ilaria Laface; Giada Zambonini; Andrea Lomagno; Marine Rouillon; Serena G. Giannelli; Fabrizio Benedicenti; Francesco Gazzo; Sergio Arévalo; Giulio Spinozzi; Francesca Sanvito; Mario Amendola; Vania Broccoli; Eugenio Montini; Angela Gritti; Vasco Meneghini
AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain

AAV载体在人iPSC来源的中枢神经系统模型和鼠脑中触发依赖DNA损伤反应的促炎信号。

NATURE COMMUNICATIONS
IF15.7
2025-04-180
OA
Costa-Verdera, Helena; Meneghini, Vasco; Fitzpatrick, Zachary; Abou Alezz, Monah; Fabyanic, Emily; Huang, Xin; Dzhashiashvili, Yulia; Ahiya, Avantika; Mangiameli, Elisabeth; Valeri, Erika; Crivicich, Giovanni; Piccolo, Silvia; Cuccovillo, Ivan; Caccia, Roberta; Chan, Ying Kai; Bertin, Berangere; Ronzitti, Giuseppe; Engel, Esteban A.; Merelli, Ivan; Mingozzi, Federico; Gritti, Angela; Kuranda, Klaudia; Kajaste-Rudnitski, Anna
RETRACTION: Coordinated involvement of cathepsins S, D and cystatin C in the commitment of hematopoietic stem cells to dendritic cells (Retraction of Vol 43, Pg 775, 2011)
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
IF2.8
2022-06-010
PRE
Martino, Sabat; Tiribuzi, Roberto; Ciraci, Elisa; Makrypidi, Georgia; D'Angelo, Francesco; Di Girolamo, Ilaria; Gritti, Angela; de Angelis, Gabriella M. Cusella; Papaccio, Gianpaolo; Sampaolesi, Maurilio; Berardi, Anna Concetta; Datti, Alessandro; Orlacchio, Aldo
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutieres syndrome astrocytes
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2022-03-0947
OAAI
Giordano, Anna Maria Sole; Luciani, Marco; Gatto, Francesca; Abou Alezz, Monah; Beghe, Chiara; Della Volpe, Lucrezia; Migliara, Alessandro; Valsoni, Sara; Genua, Marco; Dzieciatkowska, Monika; Frati, Giacomo; Tahraoui-Bories, Julie; Giliani, Silvia Clara; Orcesi, Simona; Fazzi, Elisa; Ostuni, Renato; D'Alessandro, Angelo; Di Micco, Raffaella; Merelli, Ivan; Lombardo, Angelo; Reijns, Martin A. M.; Gromak, Natalia; Gritti, Angela; Kajaste-Rudnitski, Anna
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy

人诱导多能干细胞衍生的真正神经干细胞的产生，用于异染性脑白质营养不良的离体基因治疗

STEM CELLS TRANSLATIONAL MEDICINE
IF4.9
2016-09-1663
OAAI
Meneghini, Vasco; Frati, Giacomo; Sala, Davide; De Cicco, Silvia; Luciani, Marco; Cavazzin, Chiara; Paulis, Marianna; Mentzen, Wieslawa; Morena, Francesco; Giannelli, Serena; Sanvito, Francesca; Villa, Anna; Bulfone, Alessandro; Broccoli, Vania; Martino, Sabata; Gritti, Angela
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy

通过脑内慢病毒基因疗法在正常和受Krabbe影响的非人灵长类动物的中枢神经系统中普遍提供治疗性溶酶体酶

EMBO MOLECULAR MEDICINE
IF8.3
2016-03-2946
OAAI
Meneghini, Vasco; Lattanzi, Annalisa; Tiradani, Luigi; Bravo, Gabriele; Morena, Francesco; Sanvito, Francesca; Calabria, Andrea; Bringas, John; Fisher-Perkins, Jeanne M.; Dufour, Jason P.; Baker, Kate C.; Doglioni, Claudio; Montini, Eugenio; Bunnell, Bruce A.; Bankiewicz, Krystof; Martino, Sabata; Naldini, Luigi; Gritti, Angela

研究方向

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S
Sabata Martino
H 指数:42论文数:216被引数:6,680
A
Angelo L. Vescovi
H 指数:66论文数:369被引数:2.5万
F
Francesco Morena
H 指数:25论文数:103被引数:2,488
A
A Ricca
H 指数:8论文数:27被引数:289
L
Luigi Naldini
H 指数:120论文数:572被引数:6.2万
V
Vasco Meneghini
H 指数:17论文数:34被引数:1,153
M
Margherita Neri
H 指数:49论文数:328被引数:1.0万
A
Aldo Orlacchio
H 指数:33论文数:193被引数:2,958
H 指数:0论文数:23被引数:1,021
I
Ilaria di Girolamo
H 指数:9论文数:36被引数:375