Carlos F. Lagos - Publications, H-index & Citations

Carlos F. Lagos

chemical biology and drug discovery lab

23H指数

89论文数

1.5K被引数

收录论文 47

发表时间

GPER and EGFR cross-talk highlight aldosterone- and MR antagonist-induced NO production in cultured endothelial cells GPER和EGFR的串扰突出了醛固酮和MR拮抗剂诱导的NO产生在培养的血管内皮细胞中

Frontiers in Pharmacology

IF4.8

2026-09-02

OAAI

RP Renata Paredes; MV M. Verónica Donoso; CF Carlos F. Lagos; CC César Cárdenas; CA Claudio Acuña-Castillo; DV Daniel Valdes; LC Luis Constandil; JP Juan Pablo Huidobro-Toro

Nanostructured Lipid Carriers Enhance Ciprofloxacin Antibacterial Activity Through Diffusion-Controlled Release and Modulation of Bacterial Growth Kinetics 纳米结构脂质载体通过扩散控制释放和调节细菌生长动力学增强环丙沙星抗菌活性

Pharmaceutics

IF5.5

2026-04-17

OAAI

Javiera Carrasco-Rojas; Felipe I. Sandoval; Javiera Solas-Soto; Christina M. A. P. Schuh; Lorena Rubio-Quiroz; Carlos F. Lagos; Francisco Arriagada; Andrea C. Ortiz

Nanostructured Lipid Carriers as Physicochemical Modulators of Complex Natural Extracts: Release Behavior and Bile-Induced Remodeling in Biorelevant Media 纳米结构脂质载体作为复杂天然提取物物理化学修饰剂：释放行为及在生物相关介质中的胆汁诱导重塑

Molecules

IF4.6

2026-04-03

OAAI

Javiera Carrasco-Rojas; Javiera Solas-Soto; Rubén Veas-Albornoz; Carlos F. Lagos; Mario J. Simirgiotis; Francisco Arriagada; Andrea C. Ortiz

HERPUD1 mediates palmitic acid-induced UPR sustaining TNBC aggressiveness and is destabilized by CK2 pharmacological inhibition HERPUD1介导棕榈酸诱导的UPR以维持TNBC侵袭性，并被CK2药理抑制所破坏。

Cell Death & Disease

IF9.6

2025-11-05

OAAI

Laura Hernández-Torres; Viviana A. Cavieres; Omar Cortés; Eloisa Arias-Muñoz; Francisca Cruzat-Arias; Jorge Catalán-Aguilera; Javiera Álvarez-Indo; Macarena Aguilera-Olguín; Ronny Hernández; Eduardo Silva-Pavez; Julio C. Tapia; Jorge Cancino; Carlos F. Lagos; Tammy P. Pástor; Abigail J. Galarza; Gonzalo A. Mardones; Manuel Varas-Godoy; Nicole Villarreal-Cruz; Franz Villarroel-Espindola; Isabel Saffie; Alfonso González; María José Barrera; Pamela Ehrenfeld; Patricia V. Burgos

A complex multisystem disorder including hypopituitarism and hypoparathyroidism, associated with mutation in the gene encoding fatty acid synthase (FASN)

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2025-07-01

PREAI

Gregory, L. C.; Krywawych, S.; Rahman, S.; Lagos, Carlos F.; Eaton, S.; Dattani, M. T.

Novel 5-HT6R modulators as mTOR-dependent neuronal autophagy inductors

SCIENTIFIC REPORTS

IF3.9

2025-03-11

OAAI

Alcaino, Jose Miguel; Vera, Gonzalo; Almarza, Gonzalo; Lagos, Carlos F.; Terraza, Claudio A.; del Campo, Andrea; Recabarren-Gajardo, Gonzalo

A conserved NR5A1-responsive enhancer regulates SRY in testis-determination

NATURE COMMUNICATIONS

IF15.7

2024-03-30

OAAI

Houzelstein, Denis; Eozenou, Caroline; Lagos, Carlos F.; Elzaiat, Maeva; Bignon-Topalovic, Joelle; Gonzalez, Inma; Laville, Vincent; Schlick, Laurene; Wankanit, Somboon; Madon, Prochi; Kirtane, Jyotsna; Athalye, Arundhati; Buonocore, Federica; Bigou, Stephanie; Conway, Gerard S.; Bohl, Delphine; Achermann, John C.; Bashamboo, Anu; McElreavey, Ken

Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-11-02

OAAI

Guo, Anni; Zhang, Huiqi; Li, Huanhuan; Chiu, Arthur; Garcia-Rodriguez, Claudia; Lagos, Carlos F.; Saez, Juan C.; Lau, Chunyue Geoffrey

PCSK9 conjugated liposomes for targeted delivery of paclitaxel to the cancer cell: A proof-of-concept study

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2022-09-01

OAAI

Charbe, Nitin Bharat; Lagos, Carlos F.; Ortiz, Cristian Andres Vilos; Tambuwala, Murtaza; Palakurthi, Sushesh Srivatsa; Zacconi, Flavia C.

Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency

JCI INSIGHT

IF6.1

2022-03-08

OAAI

McGlacken-Byrne, Sinead M.; del Valle, Ignacio; Stabej, Polona Le Quesne; Bellutti, Laura; Garcia-Alonso, Luz; Ocaka, Louise A.; Ishida, Miho; Suntharalingham, Jenifer P.; Gagunashvili, Andrey; Ogunbiyi, Olumide K.; Mistry, Talisa; Buonocore, Federica; Crespo, Berta; Moreno, Nadjeda; Niola, Paola; Brooks, Tony; Brain, Caroline E.; Dattani, Mehul T.; Kelberman, Daniel; Vento-Tormo, Roser; Lagos, Carlos F.; Livera, Gabriel; Conway, Gerard S.; Achermann, John C.

Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT6 Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity

PHARMACEUTICALS

IF4.8

2021-06-01

OAAI

Arrieta-Rodriguez, Loreto; Espinoza-Rosales, Daniela; Vera, Gonzalo; Cho, Young Hwa; Cabezas, David; Vasquez-Velasquez, David; Mella-Raipan, Jaime; Lagos, Carlos F.; Recabarren-Gajardo, Gonzalo

Dynamic Optimization for Airline Maintenance Operations 航空公司维修作业的动态优化

TRANSPORTATION SCIENCE

IF4.8

2020-07-01

PREAI

Lagos, Carlos; Delgado, Felipe; Klapp, Mathias A.

Eplerenone Implantation Improved Adipose Dysfunction Averting RAAS Activation and Cell Division

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2020-04-21

OAAI

Vecchiola, Andrea; Fuentes, Cristobal A.; Solar, Isidora; Lagos, Carlos F.; Opazo, Maria Cecilia; Munoz-Durango, Natalia; Riedel, Claudia A.; Owen, Gareth, I; Kalergis, Alexis M.; Fardella, Carlos E.

Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation

NATURE COMMUNICATIONS

IF15.7

2020-02-26

OAAI

Cisterna, Bruno A.; Vargas, Anibal A.; Puebla, Carlos; Fernandez, Paola; Escamilla, Rosalba; Lagos, Carlos F.; Matus, Maria F.; Vilos, Cristian; Cea, Luis A.; Barnafi, Esteban; Gaete, Hugo; Escobar, Daniel F.; Cardozo, Christopher P.; Saez, Juan C.

Innovative Three-Step Microwave-Promoted Synthesis of N-Propargyltetrahydroquinoline and 1,2,3-Triazole Derivatives as a Potential Factor Xa (FXa) Inhibitors: Drug Design, Synthesis, and Biological Evaluation

MOLECULES

IF4.6

2020-01-23

OAAI

Santana-Romo, Fabian; Lagos, Carlos F.; Duarte, Yorley; Castillo, Francisco; Moglie, Yanina; Maestro, Miguel A.; Charbe, Nitin; Zacconi, Flavia C.

Detection of a novel severe mutation affecting the CYP21A2 gene in a Chilean male with salt wasting congenital adrenal hyperplasia

ENDOCRINE

IF2.9

2019-09-30

PREAI

Arteaga, Eugenio; Valenzuela, Felipe; Lagos, Carlos F.; Lagos, Marcela; Martinez, Alejandra; Baudrand, Rene; Carvajal, Cristian; Fardella, Carlos E.

Identification and functional analysis of missense mutations in the lecithin cholesterol acyltransferase gene in a Chilean patient with hypoalphalipoproteinemia

LIPIDS IN HEALTH AND DISEASE

IF4.2

2019-06-05

OAAI

Tobar, Hugo E.; Cataldo, Luis R.; Gonzalez, Trinidad; Rodriguez, Ricardo; Serrano, Valentina; Arteaga, Antonio; Alvarez-Mercado, Ana; Lagos, Carlos F.; Vicuna, Lucas; Miranda, Jose P.; Pereira, Ana; Bravo, Carolina; Aguilera, Concepcion M.; Eyheramendy, Susana; Uauy, Ricardo; Martinez, Alvaro; Gil, Angel; Francone, Omar; Rigotti, Attilio; Santos, Jose L.

Clinical, Biochemical, and Genetic Characteristics of Nonclassic Apparent Mineralocorticoid Excess Syndrome

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2018-09-14

OAAI

Tapia-Castillo, Alejandra; Baudrand, Rene; Vaidya, Anand; Campino, Carmen; Allende, Fidel; Valdivia, Carolina; Vecchiola, Andrea; Lagos, Carlos F.; Fuentes, Cristobal A.; Solari, Sandra; Martinez-Aguayo, Alejandro; Garcia, Hernan; Carvajal, Cristian A.; Fardella, Carlos E.

Sodium Intake Is associated With Endothelial Damage Biomarkers and Metabolic Dysregulation

AMERICAN JOURNAL OF HYPERTENSION

IF3.1

2018-06-16

OAAI

Campino, Carmen; Baudrand, Rene; Valdivia, Carolina A.; Carvajal, Cristian; Vecchiola, Andrea; Tapia-Castillo, Alejandra; Martinez-Aguayo, Alejandro; Garcia, Hernan; Garcia, Lorena; Allende, Fidel; Solari, Sandra; Fuentes, Cristobal A.; Lagos, Carlos F.; Paulina Rojas, Maria; Munoz, Doris; Fardella, Carlos E.

Serum Cortisol and Cortisone as Potential Biomarkers of Partial 11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency

AMERICAN JOURNAL OF HYPERTENSION

IF3.1

2018-03-30

OAAI

Carvajal, Cristian A.; Tapia-Castillo, Alejandra; Valdivia, Carolina P.; Allende, Fidel; Solari, Sandra; Lagos, Carlos F.; Campino, Carmen; Martinez-Aguayo, Alejandro; Vecchiola, Andrea; Pinochet, Constanza; Godoy, Claudia; Iturrieta, Virginia; Baudrand, Rene; Fardella, Carlos E.

研究方向