未登录 分享 收藏
Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness Barkan, David T.; Garland, Keira; Zhang, Lei; Eastman, Richard T.; Hesse, Matthew; Knapp, Mark; Ornelas, Elizabeth; Tang, Jenny; Cortopassi, Wilian Augusto; Wang, Yu; King, Frederick; Jia, Weiping; Nguyen, Zachary; Frank, Andreas O.; Chan, Ryan; Fang, Eric; Fuller, Daniel; Busby, Scott; Carias, Heidi; Donahue, Kristine; Tandeske, Laura; Diagana, Thierry T.; Jarrousse, Nadine; Moser, Heinz; Sarko, Christopher; Dovala, Dustin; Moquin, Stephanie; Marx, Vanessa M. 分享 收藏
A high throughput cell stretch device for investigating mechanobiology in vitro Pratt, Stephen J. P.; Plunkett, Christopher M.; Kuzu, Guray; Trinh, Ton; Barbara, Joshua; Choconta, Paula; Quackenbush, Doug; Huynh, Truc; Smith, Anders; Barnes, S. Whitney; New, Joel; Pierce, James; Walker, John R.; Mainquist, James; King, Frederick J.; Elliott, Jimmy; Hammack, Scott; Decker, Rebekah S. 分享 收藏
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter-Compounds with Novel Mechanisms from High-Throughput Screening Profiles Thomas, Jason R.; Shelton, Claude; Murphy, Jason; Brittain, Scott; Bray, Mark-Anthony; Aspesi, Peter; Concannon, John; King, Frederick J.; Ihry, Robert J.; Ho, Daniel J.; Henault, Martin; Hadjikyriacou, Andrea; Neri, Marilisa; Sigoillot, Frederic D.; Pham, Helen T.; Shum, Matthew; Barys, Louise; Jones, Michael D.; Martin, Eric J.; Blechschmidt, Anke; Rieffel, Sebastien; Troxler, Thomas J.; Mapa, Felipa A.; Jenkins, Jeremy L.; Jain, Rishi K.; Kutchukian, Peter S.; Schirle, Markus; Renner, Steffen 分享 收藏
Drug target prediction through deep learning functional representation of gene signatures 通过基因特征的深度学习功能表示进行药物靶标预测 Chen, Hao; King, Frederick J.; Zhou, Bin; Wang, Yu; Canedy, Carter J.; Hayashi, Joel; Zhong, Yang; Chang, Max W.; Pache, Lars; Wong, Julian L.; Jia, Yong; Joslin, John; Jiang, Tao; Benner, Christopher; Chanda, Sumit K.; Zhou, Yingyao 分享 收藏
Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles and Deep Learning Godinez, William J.; Trifonov, Vladimir; Fang, Bin; Kuzu, Guray; Pei, Luying; Guiguemde, W. Armand; Martin, Eric J.; King, Frederick J.; Jenkins, Jeremy L.; Skewes-Cox, Peter 分享 收藏
Integrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors Tiedt, Ralph; King, Frederick J.; Stamm, Christelle; Niederst, Matthew J.; Delach, Scott; Zumstein-Mecker, Sabine; Meltzer, Jodi; Mulford, Iain J.; Labrot, Emma; Engstler, Barbara Schacher; Baltschukat, Sabrina; Kerr, Grainne; Golji, Javad; Wyss, Daniel; Schnell, Christian; Ainscow, Edward; Engelman, Jeffrey A.; Sellers, William R.; Barretina, Jordi; Caponigro, Giordano; Porta, Diana Graus 分享 收藏
The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease 强效和选择性的RIPK2抑制剂BI 706039改善炎症性肠病的TRUC小鼠模型中的肠道炎症 Ermann, Joerg; Matmusaev, Mederbek; Haley, Emma K.; Braun, Clemens; Jost, Felix; Mayer-Wrangowski, Svenja; Hsiao, Peng; Ting, Naitee; Li, Li; Terenzio, Donna; Chime, Jane; Lukas, Susan; Patnaude, Lori; Panzenbeck, Mark; Csordas, David; Zheng, Jie; Mierz, Diane; Simpson, Tom; King, F. James; Klimowicz, Alex P.; Mbow, M. Lamine; Fine, Jay S.; Miller, Craig A.; Fogal, Steve E.; Byrne, Fergus R. 分享 收藏
EndoBind detects endogenous protein-protein interactions in real time Bill, Anke; Espinola, Sheryll; Guthy, Daniel; Haling, Jacob R.; Lanter, Mylene; Lu, Min; Marelli, Anthony; Mendiola, Angelica; Miraglia, Loren; Taylor, Brandon L.; Vargas, Leonardo; Orth, Anthony P.; King, Frederick J. 分享 收藏
Dark chemical matter as a promising starting point for drug lead discovery Wassermann, Anne Mai; Lounkine, Eugen; Hoepfner, Dominic; Le Goff, Gaelle; King, Frederick J.; Studer, Christian; Peltier, John M.; Grippo, Melissa L.; Prindle, Vivian; Tao, Jianshi; Schuffenhauer, Ansgar; Wallace, Iain M.; Chen, Shanni; Krastel, Philipp; Cobos-Correa, Amanda; Parker, Christian N.; Davies, John W.; Glick, Meir 分享 收藏
Combinatorial CDK4/6 and ALK inhibition demonstrates on -target synergy against neuroblastoma Wood, Andrew C.; Krytska, Kateryna; Ryles, Hannah; Sano, Renata; Hansel, Theodore; Li, Nanxin; King, Frederick; Smith, Timothy; Tuntland, Tove; Kim, Sunkyu; Caponigro, Giordano; He, You-Qun; Harris, Jennifer; Mosse, Yael 分享 收藏
Combination CDK4/6 and ALK inhibition demonstrates on-target synergy against neuroblastoma Wood, Andrew C.; Krytska, Kateryna; Ryles, Hannah; Sano, Renata; Li, Nanxin; King, Frederick; Smith, Timothy; Tuntland, Tove; Kim, Sunkyu; Caponigro, Giordano; He, You Qun; Jennifer, Harris; Mosse, Yael 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
An efficient rapid system for profiling the cellular activities of molecular libraries 用于分析分子库细胞活性的高效快速系统 Melnick, JS; Janes, J; Kim, S; Chang, JY; Sipes, DG; Gunderson, D; Jarnes, L; Matzen, JT; Garcia, ME; Hood, TL; Beigi, R; Xia, G; Harig, RA; Asatryan, H; Yan, SF; Zhou, YY; Gu, XJ; Saadat, A; Zhou, V; King, FJ; Shaw, CM; Su, AI; Downs, R; Gray, NS; Schultz, PG; Warmuth, M; Caldwell, JS 分享 收藏
Genome-scale functional profiling of the mammalian AP-1 signaling pathway Chanda, SK; White, S; Orth, AP; Reisdorph, R; Miraglia, L; Thomas, RS; DeJesus, P; Mason, DE; Huang, QH; Vega, R; Yu, DH; Nelson, CG; Smith, BM; Terry, R; Linford, AS; Yu, Y; Chirn, GW; Song, CZ; Labow, MA; Cohen, D; King, FJ; Peters, EC; Schultz, PG; Vogt, PK; Hogenesch, JB; Caldwell, JS 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
