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Samantha P. Harris

University of Arizona

H指数:34

被引数:3,830

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Beyond the N-terminus: Emerging regulatory roles of the middle and C-terminal domains of cardiac myosin binding protein-C

超越N端：心肌肌球蛋白结合蛋白C的中部和C末端结构域的 emerging regulatory roles

Journal of Molecular and Cellular Cardiology

IF4.7

2026-07-280

PRE

Mavacamten facilitates myosin head ON-to-OFF transitions and shortens thin filament length in relaxed mouse skeletal muscle

PHYSIOLOGICAL REPORTS

IF1.9

2025-10-270

OAAI

Myosin-binding protein C slows cardiac myofibril relaxation kinetics

肌球蛋白结合蛋白C减慢心肌肌原纤维松弛动力学

IF0

2025-09-110

PRE

The L348P point mutation in cardiac myosin binding protein-C alters transient responses to stretch, slows cardiac relaxation, and is embryonic lethal in homozygous CRISPR gene-edited mice

心肌肌球蛋白结合蛋白C中的L348P点突变改变了拉伸刺激的瞬时反应，延缓了心肌舒张，并且在同源CRISPR基因编辑小鼠中是致死的。

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2025-06-010

PRE

Autoinhibition of cMyBP-C by its middle domains

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2025-03-010

OAAI

Single Cell Transcriptomic Profiling of MYBPC3-Associated Hypertrophic Cardiomyopathy Across Species Reveals Conservation of Biological Process But Not Gene Expression

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2025-01-070

OAAI

Artificial Intelligence Tool Accurately Predicts Occlusion Myocardial Infarction And May Reduce False-Positive Cath Lab Activations

人工智能工具可准确预测闭塞心肌梗死，并可能减少导管室误激活的假阳性率

IF38.6

2024-11-120

PRE

Cardiac myosin inhibitor, CK-586, minimally reduces systolic function and ameliorates obstruction in feline hypertrophic cardiomyopathy

SCIENTIFIC REPORTS

IF3.9

2024-05-271

OAAI

Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads

NATURE COMMUNICATIONS

IF15.7

2024-03-233

OAAI

Single Nuclei RNA Sequencing Analysis Of Mybpc-3Associated HCM To Identify Common Pathological Mechanisms In Human, Feline, And Murine Hearts

CIRCULATION RESEARCH

IF16.2

2023-08-040

PRE

Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C

SCIENTIFIC REPORTS

IF3.9

2023-06-267

OAAI

Frequency of Herb and Spice Use Among the South-Asian Adult Population in the United States: A Pilot Study

IF38.6

2023-02-280

PRE

Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy

SCIENTIFIC REPORTS

IF3.9

2023-01-0212

OAAI

Ambulatory electrocardiography, heart rate variability, and pharmacologic stress testing in cats with subclinical hypertrophic cardiomyopathy

SCIENTIFIC REPORTS

IF3.9

2022-02-045

OAAI

Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2022-01-0115

OAAI

Making waves: A proposed new role for myosin-binding protein C in regulating oscillatory contractions in vertebrate striated muscle

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2020-12-0428

OAAI

A Novel Cut and Paste Method for In Situ Replacement of cMyBP-C Reveals a New Role for cMyBP-C in the Regulation of Contractile Oscillations

CIRCULATION RESEARCH

IF16.2

2020-03-1325

OAAI

C0 Ig-Domain of Cardiac Myosin Binding Protein-C Interacts with the Regulatory Light Chain of Myosin-S1 Bound to the Native Cardiac Thin Filament

BIOPHYSICAL JOURNAL

IF3.1

2019-02-010

OAAI

Acute Loss of cMyBP-C Induces Auto-Oscillatory Contractions in Permeabilized Cardiomyocytes: Implications for Reverse E-C Coupling?

BIOPHYSICAL JOURNAL

IF3.1

2019-02-010

OAAI

Point mutations in the tri-helix bundle of the M-domain of cardiac myosin binding protein-C influence systolic duration and delay cardiac relaxation

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2018-06-0121

OAAI