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Effect of cross-platform gene-expression, computational methods on breast cancer subtyping in PALOMA-2 and PALLET studies Cheang, Maggie Chon U.; Rimawi, Mothaffar; Johnston, Stephen; Jacobs, Samuel A.; Bliss, Judith; Pogue-Geile, Katherine; Kilburn, Lucy; Zhu, Zhou; Schuster, Eugene F.; Xiao, Hui; Swaim, Lisa; Deng, Shibing; Lu, Dongrui R.; Gauthier, Eric; Tursi, Jennifer; Slamon, Dennis J.; Rugo, Hope S.; Finn, Richard S.; Liu, Yuan 分享 收藏
Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer Hermida-Prado, Francisco; Xie, Yingtian; Sherman, Shira; Nagy, Zsuzsanna; Russo, Douglas; Akhshi, Tara; Chu, Zhengtao; Feit, Avery; Campisi, Marco; Chen, Minyue; Nardone, Agostina; Guarducci, Cristina; Lim, Klothilda; Font-Tello, Alba; Lee, Irene; Garcia-Pedrero, Juana; Canadas, Israel; Agudo, Judith; Huang, Ying; Sella, Tal; Jin, Qingchun; Tayob, Nabihah; Mittendorf, Elizabeth A.; Tolaney, Sara M.; Qiu, Xintao; Long, Henry; Symmans, William F.; Lin, Jia-Ren; Santagata, Sandro; Bedrosian, Isabelle; Yardley, Denise A.; Mayer, Ingrid A.; Richardson, Edward T.; Oliveira, Giacomo; Wu, Catherine J.; Schuster, Eugene F.; Dowsett, Mitch; Welm, Alana L.; Barbie, David; Metzger, Otto; Jeselsohn, Rinath 分享 收藏
Molecular profiling of aromatase inhibitor sensitive and resistant ER+HER2-postmenopausal breast cancers Schuster, Eugene F.; Lopez-Knowles, Elena; Alataki, Anastasia; Zabaglo, Lila; Folkerd, Elizabeth; Evans, David; Sidhu, Kally; Cheang, Maggie Chon U.; Tovey, Holly; Salto-Tellez, Manuel; Maxwell, Perry; Robertson, John; Smith, Ian; Bliss, Judith M.; Dowsett, Mitch 分享 收藏
The proteomic landscape of soft tissue sarcomas Burns, Jessica P.; Wilding, Christopher; Krasny, Lukas; Zhu, Xixuan; Chadha, Madhumeeta; Tam, Yuen Bun; Hari, P. S. H.; Mahalingam, Aswanth; Lee, Alexander T. J.; Arthur, Amani; Guljar, Nafia; Perkins, Emma; Pankova, Valeriya; Jenks, Andrew; Djabatey, Vanessa; Szecsei, Cornelia; McCarthy, Frank; Ragulan, Chanthirika; Milighetti, Martina I.; Roumeliotis, Theodoros; Crosier, Stephen; Finetti, Martina S.; Choudhary, Jyoti; Judson, Ian; Fisher, Cyril F.; Schuster, Eugene; Sadanandam, Anguraj W.; Chen, Tom; Williamson, Daniel; Thway, Khin L.; Jones, Robin; Cheang, Maggie C. U. H.; Huang, Paul 分享 收藏
A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island Choi, JD; Underkoffler, LA; Wood, AJ; Collins, JN; Williams, PT; Golden, JA; Schuster, EF; Loomes, KM; Oakey, RJ 分享 收藏
Low plasma estradiol, low expression of estrogen responsive genes and TP53 mutations are associated with poor anti-proliferative response to aromatase inhibitors Schuster, Eugene F.; Lopez-Knowles, Elena; Alataki, Anastasia; Zabaglo, Lila; Folkerd, Elizabeth; Evans, David; Sidhu, Kally; Tovey, Holly; Maxwell, Perry; Turner, Nicholas; Johnston, Stephen; Salto-Tellez, Manuel; Cheang, Maggie Chon U.; Robertson, John; Smith, Ian; Bliss, Judith; Dowsett, Mitch 分享 收藏
Elacestrant demonstrates strong anti-estrogenic activity in PDX models of estrogen-receptor positive endocrine-resistant and fulvestrant-resistant breast cancer Pancholi, Sunil; Simigdala, Nikiana; Ribas, Ricardo; Schuster, Eugene; Leal, Mariana Ferreira; Nikitorowicz-Buniak, Joanna; Rega, Camilla; Bihani, Teeru; Patel, Hitisha; Johnston, Stephen R.; Dowsett, Mitch; Martin, Lesley-Ann 分享 收藏
Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study Lopez-Knowles, Elena; Detre, Simone; Hills, Margaret; Schuster, Eugene F.; Cheang, Maggie C. U.; Tovey, Holly; Kilburn, Lucy S.; Bliss, Judith M.; Robertson, John; Mallon, Elizabeth; Skene, Anthony; Evans, Abigail; Smith, Ian; Dowsett, Mitch 分享 收藏
HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer Bergamino, Milana A.; Lopez-Knowles, Elena; Morani, Gabriele; Tovey, Holly; Kilburn, Lucy; Schuster, Eugene F.; Alataki, Anastasia; Hills, Margaret; Xiao, Hui; Holcombe, Chris; Skene, Anthony; Robertson, John F.; Smith, Ian E.; Bliss, Judith M.; Dowsett, Mitch; Cheang, Maggie C. U. 分享 收藏
Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor-positive Breast Cancers Bergamino, Milana A.; Morani, Gabriele; Parker, Joel; Schuster, Eugene F.; Leal, Mariana F.; Lopez-Knowles, Elena; Tovey, Holly; Bliss, Judith M.; Robertson, John F. R.; Smith, Ian E.; Dowsett, Mitch; Cheang, Maggie C. U. 分享 收藏
Overlapping molecular features (proliferation, immune signatures andTP53mutations) associated with palbociclib resistance inER+HER2-primary breast cancer Schuster, Eugene F.; Xiao, Hui; Cheang, Maggie; Lopez-Knowles, Elena; Kilburn, Lucy; Korchina, Viktoriya; Salvi, Sejal; Jacobs, Samuel A.; Finnigan, Melanie; Wheeler, David A.; Puhalla, Shannon; Muzny, Donna; Doddapaneni, Harsha; Pogue-Geile, Katherine; Liu, Yuan; Bliss, Judith; Johnston, Stephen; Dowsett, Mitch; Rimawi, Mothaffar 分享 收藏
Impact of using cross-platform gene expression profiling technologies and computational methods for intrinsic breast cancer subtyping in PALOMA-2 and PALLET Cheang, Maggie; Dowsett, Mitch; Rimawi, Mothaffar; Johnston, Stephen; Jacobs, Samuel; Bliss, Judith; Pogue-Geile, Katherine; Kilburn, Lucy; Zhu, Zhou; Schuster, Eugene F.; Xiao, Hui; Swaim, Lisa; Deng, Shibing; Lu, Dongrui R.; Gauthier, Eric; Tursi, Jennifer; Slamon, Dennis J.; Rugo, Hope S.; Finn, Richard S.; Liu, Yuan 分享 收藏
Development and validation for research assessment of Oncotype DX® Breast Recurrence Score, EndoPredict® and Prosigna® Buus, Richard; Szijgyarto, Zsolt; Schuster, Eugene F.; Xiao, Hui; Haynes, Ben P.; Sestak, Ivana; Cuzick, Jack; Pare, Laia; Segui, Elia; Chic, Nuria; Prat, Aleix; Dowsett, Mitch; Cheang, Maggie Chon U. 分享 收藏
Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities Pancholi, Sunil; Ribas, Ricardo; Simigdala, Nikiana; Schuster, Eugene; Nikitorowicz-Buniak, Joanna; Ressa, Anna; Gao, Qiong; Leal, Mariana Ferreira; Bhamra, Amandeep; Thornhill, Allan; Morisset, Ludivine; Montaudon, Elodie; Sourd, Laura; Fitzpatrick, Martin; Altelaar, Maarten; Johnston, Stephen R.; Marangoni, Elisabetta; Dowsett, Mitch; Martin, Lesley-Ann 分享 收藏
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Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance Pearson, Alex; Proszek, Paula; Pascual, Javier; Fribbens, Charlotte; Shamsher, Monee K.; Kingston, Belinda; O'Leary, Ben; Herrera-Abreu, Maria T.; Cutts, Rosalind J.; Garcia-Murillas, Isaac; Bye, Hannah; Walker, Brian A.; De Castro, David Gonzalez; Yuan, Lina; Jamal, Sabri; Hubank, Mike; Lopez-Knowles, Elena; Schuster, Eugene F.; Dowsett, Mitch; Osin, Peter; Nerurkar, Ashutosh; Parton, Marina; Okines, Alicia F. C.; Johnston, Stephen R. D.; Ring, Alistair; Turner, Nicholas C. 分享 收藏
Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer (vol 21, 135, 2019) Pancholi, Sunil; Leal, Mariana Ferreira; Ribas, Ricardo; Simigdala, Nikiana; Schuster, Eugene; Chateau-Joubert, Sophie; Zabaglo, Lila; Hills, Margaret; Dodson, Andrew; Gao, Qiong; Johnston, Stephen R.; Dowsett, Mitch; Cosulich, Sabina C.; Marangoni, Elisabetta; Martin, Lesley-Ann 分享 收藏
Early Enrichment of ESR1 Mutations and the Impact on Gene Expression in Presurgical Primary Breast Cancer Treated with Aromatase Inhibitors Leal, Mariana Ferreira; Haynes, Ben P.; Schuster, Eugene; Yeo, Belinda; Afentakis, Maria; Zabaglo, Lila; Martins, Vera; Buus, Richard; Dodson, Andrew; Cheang, Maggie C. U.; Smith, Ian E.; Martin, Lesley-Ann; Dowsett, Mitch 分享 收藏
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