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张桂根 (Guigen Zhang)

institute of basic medical sciences (ibms)副教授

H指数:24

被引数:2,202

个人简介

任职于中山大学中山医学院，副教授、课题组长、博士生导师。2016年毕业于德国汉诺威医学院，获博士学位，同年受北大-清华生命科学联合中心优秀博士后基金资助，在北京大学生物医学前沿创新中心从事博士后研究。2019年10月作为中山大学“百人计划”引进人才加入中山医学院建立独立实验室。入选广东省重大人才计划-青年人才项目。主要研究成果以通讯作者或第一作者发表于Cell、PNAS、Science Advances等期刊，发现人新生儿Fc受体是大部分病毒肠道病毒的受体，并揭示其介导病毒进入细胞的分子机制。

教育背景

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工作经历

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荣誉奖项

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Ferrimagnetic Vortex Nanorings Facilitate Efficient and Safe Deep-Brain Magnetothermal Stimulation in Freely Moving Mice

铁磁涡旋纳米环促进自由活动小鼠高效且安全的深部脑磁热刺激

IF22.5

2025-12-011

OAAI

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

鉴定TPRA1作为M1溶瘤病毒的新型受体和预测性生物标志物

Advanced Science

IF14.1

2025-10-060

OAAI

Nasal mucus-derived KLK13 restricts SARS-CoV-2 infection via proteolytic cleavage of spike

鼻粘液来源的KLK13通过刺突的蛋白水解裂解限制SARS-CoV-2感染

IF4.7

2025-10-010

PRE

Proximity Labeling and Genetic Screening Reveal that DSG2 is a Counter Receptor of Siglec-9 and Suppresses Macrophage Phagocytosis

邻近标记和遗传筛选揭示DSG2是Siglec-9的配体受体，并抑制巨噬细胞吞噬作用

ADVANCED SCIENCE

IF14.1

2025-01-150

OA

Resolving the Size and Charge of Small Particles: A Predictive Model of Nanopore Mechanics

JOURNAL OF PHYSICAL CHEMISTRY C

IF3.2

2024-08-091

OAAI

Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18

IF4.7

2022-08-309

OAAI

TRIM26 is a critical host factor for HCV replication and contributes to host tropism

SCIENCE ADVANCES

IF12.5

2021-01-0831

OAAI

A computational study of the dual effect of intermittent and continuous administration of parathyroid hormone on bone remodeling

ACTA BIOMATERIALIA

IF9.6

2019-07-019

PREAI

In vivo ways to unveil off-targets

IF25.9

2019-03-193

OAAI

Electrocarving during Electrodeposition Growth

ADVANCED MATERIALS

IF26.8

2018-10-1135

PREAI

Elucidating the mechanism governing cell rotation under DEP using the volumetric polarization and integration method

BIOMEDICAL MICRODEVICES

IF3.3

2018-09-084

PREAI

High-performance piezoelectric composite nanogenerator based on Ag/(K, Na)NbO3 heterostructure

基于Ag/(K，Na)NbO3异质结构的高性能压电复合纳米发电机

IF17.1

2018-08-0199

PREAI

Elucidating the Mechanisms of Two Unique Phenomena Governed by Particle-Particle Interaction under DEP: Tumbling Motion of Pearl Chains and Alignment of Ellipsoidal Particles

IF3

2018-06-017

OAAI

Mussel-inspired fabrication of porous anodic alumina nanochannels and a graphene oxide interfacial ionic rectification device

CHEMICAL COMMUNICATIONS

IF4.2

2018-01-0120

PREAI

Seeking Convergence to advance Biomaterials Science and Translation by Chinese Association for Biomaterials

BIOACTIVE MATERIALS

IF20.3

2017-12-010

OAAI

Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency

IF4.9

2017-04-2144

OAAI

Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-01-25151

OAAI

Enhancing the performance of a fluidic glucose biosensor with 3D electrodes

SENSORS AND ACTUATORS B-CHEMICAL

IF7.7

2011-12-0114

PREAI

Energy flow analysis and hybrid controller design for non-linear electromagnetic suspension

proceedings of the institution of mechanical engineers part e journal of process mechanical engineering

IF1.5

2011-10-034

PREAI

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt-TSC2-mTOR signaling

CELL DEATH & DISEASE

IF9.6

2011-05-19171

OAAI