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N

Nicholas H. Oberlies

university of north carolina

66H指数
439论文数
1.5W被引数
收录论文 180
发表时间
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Natural product target identification of wheldone, a fungal metabolite, as a KIF11 inhibitor in ovarian cancer using the DiffPOP (Differential Protein Precipitation) method.利用DiffPOP（差异蛋白质沉淀）方法，对作为卵巢癌KIF11抑制剂的真菌代谢物wheldone进行天然产物靶点鉴定。
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2026-03-23
err0
errOAAI
errManead Khin; Alejandra Cavazos Saldana; Manuel Rangel-Grimaldo; Huzefa A. Raja; Daniel Abegg; Julia Ekiert; Chang Liu; Sweta Misra; Kiira Ratia; Alexander Adibekian; Yu Gao; Samuel K. Kulp; Christopher C. Coss; Nicholas H. Oberlies; Joanna E. Burdette
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An integrative chemical and genomic similarity approach linking fungal secondary metabolites and biosynthetic gene clusters一种整合真菌次生代谢产物和生物合成基因簇的化学和基因组相似性方法
errorg. biomol. chem.
IF0
err2026-01-26
err0
errOAAI
errKarin Steffen; Manuel Rangel-Grimaldo; Thomas J. C. Sauters; David C. Rinker; Huzefa A. Raja; Tyler N. Graf; Adiyantara Gumilang; Olivia L. Riedling; Gustavo H. Goldman; Nicholas H. Oberlies; Antonis Rokas
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Natural pigments from the endophyte Aspergillus westerdijkiae and evaluation of their bioactivities内生真菌Aspergillus westerdijkiae的天然色素及其生物活性评价
errMicrobial Cell Factories
IF4.9
err2025-12-31
err0
errOAAI
errAbirami Baskaran; Andreas Wasilewicz; Judith M. Rollinger; Joanna Grzelczyk; Ilona Gałązka-Czarnecka; Grażyna Budryn; Tomasz Strzała; Tyler N. Graf; Nicholas H. Oberlies; Filip Boratyński; El-Sayed R. El-Sayed
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An antimicrobial daptide from human skin commensal Staphylococcus hominis protects against skin pathogens一种来自人皮肤共生菌金黄色葡萄球菌的抗菌达普替肽可保护皮肤免受病原体侵害
errNature Communications
IF15.7
err2025-12-11
err0
errOAAI
errAmber Nguyen; Zoie L. Bunch; Ingrid Y. Martinez-Aldino; Manuel Rangel-Grimaldo; Uday Tak; John C. Thorstenson; Morgan M. Severn; Teruaki Nakatsuji; Richard L. Gallo; Tyler N. Graf; Nicholas H. Oberlies; Jonathan R. Chekan; Nadja B. Cech; Alexander R. Horswill
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Beyond Monomers: Discovery of Bioactive Naphthoquinone Heterodimers and Perenniporides from Pyrenochaetopsis Species超越单体：从Pyrenochaetopsis属中发现的生物活性萘醌杂二聚体和Perenniporides
errJournal of Natural Products
IF3.6
err2025-12-02
err0
errOAAI
errReema A. Al-Qiam; Manuel Rangel-Grimaldo; Isabel M. Chauvin; Elizabeth N. Kaweesa; Manead Khin; Huzefa A. Raja; Jimmy Orjala; Joanna E. Burdette; Cedric J. Pearce; Nicholas H. Oberlies
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Studying the molecular mechanisms of tef (Eragrostis tef) antioxidant properties in human THP-1 monocytes研究tef(Eragrostis tef)抗氧化特性在人类THP-1单核细胞中的分子机制
errJournal of Functional Foods
IF4
err2025-11-10
err0
errOAAI
errAnastasia V. Romanov; Tyler N. Graf; Warren Vidar; Dereje D. Jima; Nicholas H. Oberlies; Zhenquan Jia; Ayalew Ligaba-Osena
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Machine-Readable Structural Information Is Essential for Natural Products Research机器可读的结构信息对天然产物研究至关重要
errJournal of Natural Products
IF3.6
err2025-10-20
err0
errOAAI
errKarin Steffen; Nicholas H. Oberlies; Antonis Rokas
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Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling扩大真菌peryleniquinones的生产规模，并通过稳定同位素标记研究其生物合成。
errMicrobial Cell Factories
IF4.9
err2025-10-05
err0
errOAAI
errReema A. Al-Qiam; Sachin Dumbare; Tyler N. Graf; Warren S. Vidar; Huzefa A. Raja; Cedric J. Pearce; Shabnam Hematian; Nicholas H. Oberlies
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Corrigendum to ‘A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption’ [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597]勘误表：‘A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption’ [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597]
errpharmacology and experimental therapeutics
IF0
err2025-06-11
err0
PREAI
errChristopher M. Arian; Eimear T. O’Mahony; Preston K. Manwill; Tyler N. Graf; Nicholas H. Oberlies; Nadja B. Cech; John D. Clarke; Jason G. Smith; Mary F. Paine; Edward J. Kelly; Kenneth E. Thummel
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Menominin A and B: Cytotoxic Cyclodepsipeptides from the Freshwater Sponge-Associated Cyanobacterium Nostoc sp. UIC 10607
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2025-02-20
err0
PREAI
errDavis, Lydia J.; Krunic, Aleksej; Alexander, Kelsey; Khin, Manead; Wood, Jared S.; Earp, Cody; Rangel-Grimaldo, Manuel; Eustaquio, Alessandra S.; Burdette, Joanna E.; Williamson, R. Thomas; Oberlies, Nicholas H.; Orjala, Jimmy
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Evolutionary origin and population diversity of a cryptic hybrid pathogen
errNATURE COMMUNICATIONS
IF15.7
err2024-09-28
err0
errOAAI
errSteenwyk, Jacob L.; Knowles, Sonja; Bastos, Rafael W.; Balamurugan, Charu; Rinker, David; Mead, Matthew E.; Roberts, Christopher D.; Raja, Huzefa A.; Li, Yuanning; Colabardini, Ana Cristina; de Castro, Patricia Alves; dos Reis, Thaila Fernanda; Gumilang, Adiyantara; Almagro-Molto, Maria; Alanio, Alexandre; Garcia-Hermoso, Dea; Delbaje, Endrews; Pontes, Lais; Pinzan, Camila Figueiredo; Schreiber, Angelica Zaninelli; Canovas, David; Sanchez Luperini, Rafael; Lagrou, Katrien; Torrado, Egidio; Rodrigues, Fernando; Oberlies, Nicholas H.; Zhou, Xiaofan; Goldman, Gustavo H.; Rokas, Antonis
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Strain heterogeneity in a non-pathogenic Aspergillus fungus highlights factors associated with virulence
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-09-04
err0
errOAAI
errRinker, David C.; Sauters, Thomas J. C.; Steffen, Karin; Gumilang, Adiyantara; Raja, Huzefa A.; Rangel-Grimaldo, Manuel; Pinzan, Camila Figueiredo; de Castro, Patricia Alves; dos Reis, Thaila Fernanda; Delbaje, Endrews; Houbraken, Jos; Goldman, Gustavo H.; Oberlies, Nicholas H.; Rokas, Antonis
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Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster
errMETABOLOMICS
IF3.3
err2024-08-02
err1
errOAAI
errAyon, Navid J.; Earp, Cody E.; Gupta, Raveena; Butun, Fatma A.; Clements, Ashley E.; Lee, Alexa G.; Dainko, David; Robey, Matthew T.; Khin, Manead; Mardiana, Lina; Longcake, Alexandra; Rangel-Grimaldo, Manuel; Hall, Michael J.; Probert, Michael R.; Burdette, Joanna E.; Keller, Nancy P.; Raja, Huzefa A.; Oberlies, Nicholas H.; Kelleher, Neil L.; Caesar, Lindsay K.
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Wheldone Revisited: Structure Revision Via DFT-GIAO Chemical Shift Calculations, 1,1-HD-ADEQUATE NMR Spectroscopy, and X-ray Crystallography Studies
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-07-23
err2
errOAAI
errRangel-Grimaldo, Manuel; Earp, Cody E.; Raja, Huzefa A.; Wood, Jared S.; Mardiana, Lina; Ho, Kin Lok; Longcake, Alexandra; Williamson, R. Thomas; Palatinus, Lukas; Hall, Michael J.; Probert, Michael R.; Oberlies, Nicholas H.
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Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus系统基因组学揭示了曲霉属真菌菌株的广泛错误鉴定
errMICROBIOLOGY SPECTRUM
IF3.8
err2024-04-02
err9
errOAAI
errSteenwyk, Jacob L.; Balamurugan, Charu; Raja, Huzefa A.; Goncalves, Carla; Li, Ningxiao; Martin, Frank; Berman, Judith; Oberlies, Nicholas H.; Gibbons, John G.; Goldman, Gustavo H.; Geiser, David M.; Houbraken, Jos; Hibbett, David S.; Rokas, Antonis
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Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice
errPHARMACEUTICAL RESEARCH
IF4.3
err2024-02-01
err4
PREAI
errOyanna, Victoria O.; Bechtold, Baron J.; Lynch, Katherine D.; Call, M. Ridge; Graf, Tyler N.; Oberlies, Nicholas H.; Clarke, John D.
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Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model
errEXPERIMENTAL CELL RESEARCH
IF3.5
err2024-02-01
err1
PREAI
errKuttikrishnan, Shilpa; Hasan, Maram; Prabhu, Kirti S.; El-Elimat, Tamam; Oberlies, Nicholas H.; Pearce, Cedric J.; Alali, Feras Q.; Ahmad, Aamir; Pourkarimi, Ehsan; Bhat, Ajaz A.; Yalcin, Huseyin C.; Uddin, Shahab
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Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential
errNATURAL PRODUCT REPORTS
IF10.6
err2024-01-01
err0
errOAAI
errPierre, Herma C.; Amrine, Chiraz Soumia M.; Doyle, Michael G.; Salvi, Amrita; Raja, Huzefa A.; Chekan, Jonathan R.; Huntsman, Andrew C.; Fuchs, James R.; Liu, Kebin; Burdette, Joanna E.; Pearce, Cedric J.; Oberlies, Nicholas H.
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
errJOURNAL OF DERMATOLOGICAL SCIENCE
IF4
err2023-11-01
err2
errOAAI
errKuttikrishnan, Shilpa; Masoodi, Tariq; Ahmad, Fareed; Sher, Gulab; Prabhu, Kirti S.; Mateo, Jericha M.; Buddenkotte, Joerg; El-Elimat, Tamam; Oberlies, Nicholas H.; Pearce, Cedric J.; Bhat, Ajaz A.; Alali, Feras Q.; Steinhoff, Martin; Uddin, Shahab
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Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
errCELL BIOLOGY INTERNATIONAL
IF3.1
err2023-10-26
err6
errOAAI
errKuttikrishnan, Shilpa; Ahmad, Fareed; Mateo, Jericha M.; Prabhu, Kirti S.; El-Elimat, Tamam; Oberlies, Nicholas H.; Pearce, Cedric J.; Akil, Ammira S. Alshabeeb; Bhat, Ajaz A.; Alali, Feras Q.; Uddin, Shahab
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研究方向

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