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C

Chang‐Guo Zhan

University of Kentucky

57H指数
409论文数
1.3W被引数
收录论文 178
发表时间
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Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis清道夫受体BI作为清除游离血红素的关键清道夫，对于防止溶血至关重要
errNature Communications
IF15.7
err2026-07-27
err0
errOAAI
errMisa Ito; Jianyao Xue; Ling Guo; Dan Hao; Qian Wang; Alexander H. Williams; Chang-Guo Zhan; Ailing Ji; Preetha Shridas; Wen Su; Shu Liu; Zhenheng Guo; Mingcui Gong; Scott M. Gordon; Bin Huang; Jianhang Jia; Chieko Mineo; Philip W. Shaul; Xiang-an Li
err分享
err收藏
Mutational effects of the asparagine198 and glutamate223 residues on the human norepinephrine transporter on basal and HIV-1 Tat protein-induced inhibition of dopamine transport天冬酰胺198和谷氨酸223残基对人类去甲肾上腺素转运体基础及HIV-1 Tat蛋白诱导的多巴胺转运抑制的突变效应
errEuropean Journal of Pharmacology
IF4.7
err2025-09-12
err0
PREAI
errKatherine Darby Porter; Charles Adeniran; Ana Catya Jimenez-Torres; Karl Lee Pless; Abagail Brenda Cirincione; Harper Davenport; Carolyn Chen; Chang-Guo Zhan; Jun Zhu
err分享
err收藏
A cocaine hydrolase engineered from human butyrylcholinesterase as a medical countermeasure for aldicarb poisoning从人丁酰胆碱酯酶工程改造的可卡因水解酶，作为一种乙拌磷中毒的医用解毒剂
errChemico-Biological Interactions
IF5.4
err2025-07-31
err0
PREAI
errJohnathan E. LeSaint; Nellore Bhanu Chandar; Annet Kyomuhangi; Huimei Wei; Fang Zheng; Chang-Guo Zhan
err分享
err收藏
Treatment of acute organophosphate poisoning by using a cocaine hydrolase engineered from human butyrylcholinesterase利用由人丁酰胆碱酯酶工程改造的可卡因水解酶治疗急性有机磷中毒
errCHEMICO-BIOLOGICAL INTERACTIONS
IF5.4
err2025-05-27
err0
PREAI
errLesaint, Johnathan E.; Hou, Shurong; Chandar, Nellore Bhanu; Kyomuhangi, Annet; Wei, Huimei; Zheng, Fang; Zhan, Chang-Guo
err分享
err收藏
Effects of Fentanyl-Laced Cocaine on Circulating Ghrelin, Insulin, and Glucose Levels in Rats芬太尼掺入可卡因对大鼠循环中生长素释放肽、胰岛素和葡萄糖水平的影响
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-03-06
err0
errOAAI
errWei, Huimei; Maul, Elise C.; Kyomuhangi, Annet; Park, Shawn; Mutchler, Maddilynn L.; Zhan, Chang-Guo
err分享
err收藏
Urobilin Derived from Bilirubin Bioconversion Binds Albumin and May Interfere with Bilirubin Interacting with Albumin: Implications for Disease Pathology
errBIOMEDICINES
IF3.9
err2025-01-26
err0
errOAAI
errWilliams, Kevin I.; Suryadevara, Priyanka; Zhan, Chang-Guo; Hinds Jr, Terry D.; Kipp, Zachary A.
err分享
err收藏
S6K1 is a Targetable Vulnerability in Tumors Exhibiting Plasticity and Therapy ResistanceS6K1是肿瘤中具有可靶向性的易损点，该肿瘤表现出可塑性和治疗抗性。
errINTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
IF10
err2025-01-01
err0
PREAI
errGanguly, Saptadwipa; Burikhanov, Ravshan; Sviripa, Vitaliy M.; Ellingson, Sally; Jiang, Jieyun; Gosser, Christian M.; Orren, David; Goellner, Eva M.; Shenoy, Gautham G.; Rao, Mahadev; D'Orazio, John; Brainson, Christine F.; Zhan, Chang-Guo; Spielmann, Peter H.; Watt, David S.; Rangnekar, Vivek M.
err分享
err收藏
A quantitative LC-MS/MS method for investigation of polysubstance use involving heroin and cocaine
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2024-11-01
err0
PREAI
errWei, Huimei; Deng, Jing; Zhang, Ting; Zhan, Chang-Guo; Zheng, Fang
err分享
err收藏
In vitro and in vivo stability of a highly efficient long-acting cocaine hydrolase高效长效可卡因水解酶的体外和体内稳定性
errSCIENTIFIC REPORTS
IF3.9
err2024-05-13
err0
errOAAI
errShang, Linyue; Wei, Huimei; Deng, Jing; Stewart, Madeline J.; Lesaint, Johnathan E.; Kyomuhangi, Annet; Park, Shawn; Maul, Elise C.; Zhan, Chang-Guo; Zheng, Fang
err分享
err收藏
A highly selective mPGES-1 inhibitor to block abdominal aortic aneurysm progression in the angiotensin mouse model在血管紧张素小鼠模型中阻断腹主动脉瘤进展的高选择性mPGES-1抑制剂
errSCIENTIFIC REPORTS
IF3.9
err2024-03-23
err1
errOAAI
errWeaver, Lauren M.; Stewart, Madeline J.; Ding, Kai; Loftin, Charles D.; Zheng, Fang; Zhan, Chang-Guo
err分享
err收藏
Unraveling the allosteric mechanisms of prolyl endopeptidases for celiac disease therapy: Insights from molecular dynamics simulations
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-02-01
err2
PREAI
errWang, Yongqiang; Xing, Suting; Zhao, Xinyun; Chen, Xi; Zhan, Chang-guo
err分享
err收藏
Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats
errSCIENTIFIC REPORTS
IF3.9
err2024-01-09
err0
errOAAI
errWei, Huimei; Lesaint, Johnathan E.; Jin, Zhenyu; Zhan, Chang-Guo; Zheng, Fang
err分享
err收藏
Multiobjective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-25
err3
errOAAI
errFeng, Hongsong; Wang, Rui; Zhan, Chang-Guo; Wei, Guo-Wei
err分享
err收藏
Staying Ahead of the Game: How SARS-CoV-2 has Accelerated the Application of Machine Learning in Pandemic Management
errBIODRUGS
IF6.9
err2023-07-18
err2
PREAI
errWilliams, Alexander H. H.; Zhan, Chang-Guo
err分享
err收藏
QM/MM study on the O 2 activation reaction of 4-hydroxylphenyl pyruvate dioxygenase reveals a common mechanism for ?-ketoglutarate dependent dioxygenase
errCHINESE CHEMICAL LETTERS
IF8.9
err2023-05-01
err4
PREAI
errLi, Linhui; Lai, Suitian; Lin, Hongyan; Zhao, Xinyun; Li, Xin; Chen, Xi; Liu, Junjun; Yang, Guangfu; Zhan, Changguo
err分享
err收藏
Analgesic effects of a highly selective mPGES-1 inhibitor
errSCIENTIFIC REPORTS
IF3.9
err2023-02-27
err5
errOAAI
errStewart, Madeline J.; Weaver, Lauren M.; Ding, Kai; Kyomuhangi, Annet; Loftin, Charles D.; Zheng, Fang; Zhan, Chang-Guo
err分享
err收藏
Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine
errSCIENTIFIC REPORTS
IF3.9
err2023-01-12
err8
errOAAI
errShang, Linyue; Jin, Zhenyu; Wei, Huimei; Park, Shawn; Zhan, Chang-Guo; Zheng, Fang
err分享
err收藏
Synthesis, in vitro and in silico studies on novel 3-aryloxymethyl-5-[(2-oxo-2-arylethyl)sulfanyl]-1,2,4-triazoles and their oxime derivatives as potent inhibitors of mPGES-1
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2023-01-01
err4
errOAAI
errErensoy, Gizem; Ding, Kai; Zhan, Chang-Guo; Ciftci, Gamze; Yelekci, Kemal; Duracik, Merve; Ozakpinar, Ozlem Bingol; Aydemir, Esra; Yilmaz, Zubeyde Nur; Sahin, Fikrettin; Kulabas, Necla; Tatar, Esra; Kucukguzel, Ilkay
err分享
err收藏
Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity
errMOLECULAR DIVERSITY
IF3.8
err2022-11-04
err8
PREAI
errBulbul, Bahadir; Ding, Kai; Zhan, Chang-Guo; Ciftci, Gamze; Yelekci, Kemal; Gurboga, Merve; Ozakpinar, Ozlem Bingol; Aydemir, Esra; Baybag, Deniz; Sahin, Fikrettin; Kulabas, Necla; Helvacioglu, Sinem; Charehsaz, Mohammad; Tatar, Esra; Ozbey, Suheyla; Kucukguzel, Ilkay
err分享
err收藏
Gender differences in cocaine-induced hyperactivity and dopamine transporter trafficking to the plasma membrane
errADDICTION BIOLOGY
IF2.6
err2022-10-24
err6
errOAAI
errDeng, Jing; Zheng, Xirong; Shang, Linyue; Zhan, Chang-Guo; Zheng, Fang
err分享
err收藏

研究方向

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合作学者
合作期刊
D
Donald G. Truhlar
H 指数: 187 · 论文数: 1.9K
C
Christopher J. Cramer
H 指数: 110 · 论文数: 864
D
David A. Dixon
H 指数: 97 · 论文数: 1.4K
K
Keiichi I. Nakayama
H 指数: 95 · 论文数: 558
T
Theodore J. Standiford
H 指数: 90 · 论文数: 311
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