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J

Jeannine Hess

the francis crick institute
H指数:16
被引数:983

个人简介

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教育背景

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工作经历

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荣誉奖项

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Proteome-Wide Target Identification Using Reactive Metallo-Scaffolds (r-mS): A Platform for Metallodrug Discovery

利用反应性金属骨架(r-mS)进行全蛋白质组靶点识别：金属药物发现的平台

Angewandte Chemie International Edition
IF16.9
2026-07-100
OAAI
Jessica E. Waters; Harry Wilders; George S. Biggs; Mika Kintzel; Emma E. Cawood; Jonathan Bailey; Sarah Maslen; Yew Mun Yip; Mason Wakley; Ioannis G. Riziotis; Thomas W. Rees; Joanna Redmond; J. Mark Skehel; David House; Jacob Bush; Jeannine Hess
Light-Activated Metal-Dependent Protein Degradation: A Heterobifunctional Ruthenium(II) Photosensitizer Targeting New Delhi Metallo-β-lactamase 1

光激活金属依赖性蛋白质降解：一种靶向新德里金属β-内酰胺酶1的异双功能钌(II)光敏剂

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2025-11-010
PRE
Stevens-Cullinane, Lars; Rees, Thomas W.; Evans, Calum; Ho, Po-Yu; Kintzel, Mika; Yip, Yew Mun; Jia, Ruoning; Bailey, Jonathan; Clifford, Eleanor; Alam, Ruqaiya; Maslen, Sarah; Mouilleron, Stephane; Pasquier, Adrien; Song, Ok-Ryul; Warchal, Scott; Redmond, Joanna; Howell, Michael; Kjaer, Svend; Skehel, Mark; Muller, Manuel M.; Johnson, Eachan O.; Roessler, Maxie M.; Hess, Jeannine
Discovery of Novel Inhibitors of Uridine Diphosphate-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-01-266
OA
Acebron-Garcia-de-Eulate, Marta; Mayol-Llinas, Joan; Holland, Matthew T. O.; Kim, So Yeon; Brown, Karen P.; Marchetti, Chiara; Hess, Jeannine; Di Pietro, Ornella; Mendes, Vitor; Abell, Chris; Floto, R. Andres; Coyne, Anthony G.; Blundell, Tom L.
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl-L-cysteine Synthetase (CoaB) Activity

通过化学抑制4 ′-磷酸泛酰-L-半胱氨酸合成酶 (CoaB) 活性靶向结核分枝杆菌CoaBC

ACS INFECTIOUS DISEASES
IF3.8
2021-05-035
OAAI
Evans, Joanna C.; Murugesan, Dinakaran; Post, John M.; Mendes, Vitor; Wang, Zhe; Nahiyaan, Navid; Lynch, Sasha L.; Thompson, Stephen; Green, Simon R.; Ray, Peter C.; Hess, Jeannine; Spry, Christina; Coyne, Anthony G.; Abell, Chris; Boshoff, Helena I. M.; Wyatt, Paul G.; Rhee, Kyu Y.; Blundell, Tom L.; Barry, Clifton E. I. I. I. I. I. I.; Mizrahi, Valerie
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
NATURE COMMUNICATIONS
IF15.7
2021-01-0811
OAAI
Mendes, Vitor; Green, Simon R.; Evans, Joanna C.; Hess, Jeannine; Blaszczyk, Michal; Spry, Christina; Bryant, Owain; Cory-Wright, James; Chan, Daniel S-H; Torres, Pedro H. M.; Wang, Zhe; Nahiyaan, Navid; O'Neill, Sandra; Damerow, Sebastian; Post, John; Bayliss, Tracy; Lynch, Sasha L.; Coyne, Anthony G.; Ray, Peter C.; Abell, Chris; Rhee, Kyu Y.; Boshoff, Helena I. M.; Barry, Clifton E., III; Mizrahi, Valerie; Wyatt, Paul G.; Blundell, Tom L.
In vivo active organometallic-containing antimycotic agents
RSC CHEMICAL BIOLOGY
IF3.1
2021-01-0111
OAAI
Rubbiani, Riccardo; Weil, Tobias; Tocci, Noemi; Mastrobuoni, Luciano; Jeger, Severin; Moretto, Marco; Ng, James; Lin, Yan; Hess, Jeannine; Ferrari, Stefano; Kaech, Andres; Young, Luke; Spencer, John; Moore, Anthony L.; Cariou, Kevin; Renga, Giorgia; Pariano, Marilena; Romani, Luigina; Gasser, Gilles

研究方向

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G
Gilles Gasser
H 指数:65论文数:621被引数:1.8万
C
Chris Abell
H 指数:72论文数:454被引数:2.1万
A
Anthony G. Coyne
H 指数:24论文数:140被引数:3,376
M
Malay Patra
H 指数:34论文数:176被引数:4,229
B
Bernhard Spingler
H 指数:50论文数:813被引数:8,466
T
Tom L. Blundell
H 指数:112论文数:738被引数:6.2万
V
V. Mendes
H 指数:21论文数:97被引数:1,925
S
Stefano Ferrari
H 指数:63论文数:325被引数:1.3万
V
Vanessa Pierroz
H 指数:26论文数:88被引数:2,797
T
Thomas W. Rees
H 指数:32论文数:89被引数:3,435