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I

In-Sik Kim

Lawrence Berkeley National Laboratory
H指数:16
被引数:1,050

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Unanticipated intermediates during isopenicillin N synthase catalysis identified by time-resolved X-ray free-electron laser studies

异噁唑霉素N合成酶催化过程中通过时间分辨X射线自由电子激光研究鉴定出的非预期中间体

Nature Catalysis
IF44.6
2026-10-090
OAAI
Patrick Rabe; Hiroki Makita; Rebecca Southwart; Midhun George Thomas; Mihails Kazaks; Shyam Basak; Tiankun Zhou; William K. Myers; Margaret D. Doyle; Philipp S. Simon; Shusaku Hayama; J. Frederick W. Mosselmans; Alexander T. Stead; Abraham O. Oluwole; Malkit Sami; Ian Clifton; Pierre Aller; Asmit Bhowmick; Anthony Tumber; Jos J. A. G. Kamps; Karina Calvopiña; Agata Butryn; Robert Bosman; Arjun Cheema; Jordan Welsh; James D. S. Linyard; Frederick J. H. Foster; Pauline A. Lang; Mariska de Munnik; Stephen M. Keable; Medhanjali Dasgupta; In-Sik Kim; Isabel Bogacz; Kuntal Chatterjee; Kyle D. Sutherlin; Corey J. Kaminsky; Jürgen Brem; Michael A. McDonough; Christina Redfield; James R. D. Montgomery; Coral Mycroft; Anastasya Shilova; Nicholas Devenish; Frederic P. Poitevin; Sebastian Dehe; Vandana Tiwari; Humberto Sanchez; Daniel J. Rosenberg; Mark S. Hunter; Leland B. Gee; Uwe Bergmann; Roberto Alonso-Mori; Jaehyun Park; Shigeki Owada; Kensuke Tono; Danny Axford; Robin L. Owen; Daniel W. Paley; Nicholas K. Sauter; David Mittan-Moreau; Aaron S. Brewster; Carol V. Robinson; Vittal K. Yachandra; Junko Yano; Edgars Suna; Christo Z. Christov; Allen M. Orville; Jan F. Kern; Christopher J. Schofield
In Situ Structural Observation of a Substrate- and Peroxide-Bound High-Spin Ferric-Hydroperoxo Intermediate in the P450 Enzyme CYP121
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2023-11-0810
OA
Nguyen, Romie C.; Davis, Ian; Dasgupta, Medhanjali; Wang, Yifan; Simon, Philipp S.; Butryn, Agata; Makita, Hiroki; Bogacz, Isabel; Dornevil, Kednerlin; Aller, Pierre; Bhowmick, Asmit; Chatterjee, Ruchira; Kim, In-Sik; Zhou, Tiankun; Mendez, Derek; Paley, Daniel W.; Fuller, Franklin; Mori, Roberto Alonso; Batyuk, Alexander; Sauter, Nicholas K.; Brewster, Aaron S.; Orville, Allen M.; Yachandra, Vittal K.; Yano, Junko; Kern, Jan F.; Liu, Aimin
Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography
ELIFE
IF0
2022-09-097
OA
John, Juliane; Aurelius, Oskar; Srinivas, Vivek; Saura, Patricia; Kim, In-Sik; Bhowmick, Asmit; Simon, Philipp S.; Dasgupta, Medhanjali; Pham, Cindy; Gul, Sheraz; Sutherlin, Kyle D.; Aller, Pierre; Butryn, Agata; Orville, Allen M.; Cheah, Mun Hon; Owada, Shigeki; Tono, Kensuke; Fuller, Franklin D.; Batyuk, Alexander; Brewster, Aaron S.; Sauter, Nicholas K.; Yachandra, Vittal K.; Yano, Junko; Kaila, Ville Ri; Kern, Jan; Lebrette, Hugo; Hogbom, Martin
Structural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition

在S2到S3过渡期间，光系统II的水和质子通道中的结构动力学

NATURE COMMUNICATIONS
IF15.7
2021-11-1184
OAAI
Hussein, Rana; Ibrahim, Mohamed; Bhowmick, Asmit; Simon, Philipp S.; Chatterjee, Ruchira; Lassalle, Louise; Doyle, Margaret; Bogacz, Isabel; Kim, In-Sik; Cheah, Mun Hon; Gul, Sheraz; de Lichtenberg, Casper; Chernev, Petko; Pham, Cindy C.; Young, Iris D.; Carbajo, Sergio; Fuller, Franklin D.; Alonso-Mori, Roberto; Batyuk, Alex; Sutherlin, Kyle D.; Brewster, Aaron S.; Bolotovsky, Robert; Mendez, Derek; Holton, James M.; Moriarty, Nigel W.; Adams, Paul D.; Bergmann, Uwe; Sauter, Nicholas K.; Dobbek, Holger; Messinger, Johannes; Zouni, Athina; Kern, Jan; Yachandra, Vittal K.; Yano, Junko
Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I
SCIENTIFIC REPORTS
IF3.9
2021-11-0815
OAAI
Keable, Stephen M.; Koelsch, Adrian; Simon, Philipp S.; Dasgupta, Medhanjali; Chatterjee, Ruchira; Subramanian, Senthil Kumar; Hussein, Rana; Ibrahim, Mohamed; Kim, In-Sik; Bogacz, Isabel; Makita, Hiroki; Pham, Cindy C.; Fuller, Franklin D.; Gul, Sheraz; Paley, Daniel; Lassalle, Louise; Sutherlin, Kyle D.; Bhowmick, Asmit; Moriarty, Nigel W.; Young, Iris D.; Blaschke, Johannes P.; de Lichtenberg, Casper; Chernev, Petko; Cheah, Mun Hon; Park, Sehan; Park, Gisu; Kim, Jangwoo; Lee, Sang Jae; Park, Jaehyun; Tono, Kensuke; Owada, Shigeki; Hunter, Mark S.; Batyuk, Alexander; Oggenfuss, Roland; Sander, Mathias; Zerdane, Serhane; Ozerov, Dmitry; Nass, Karol; Lemke, Henrik; Mankowsky, Roman; Brewster, Aaron S.; Messinger, Johannes; Sauter, Nicholas K.; Yachandra, Vittal K.; Yano, Junko; Zouni, Athina; Kern, Jan
X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis
SCIENCE ADVANCES
IF12.5
2021-08-2034
OAAI
Rabe, Patrick; Kamps, Jos J. A. G.; Sutherlin, Kyle D.; Linyard, James D. S.; Aller, Pierre; Pham, Cindy C.; Makita, Hiroki; Clifton, Ian; McDonough, Michael A.; Leissing, Thomas M.; Shutin, Denis; Lang, Pauline A.; Butryn, Agata; Brem, Jurgen; Gul, Sheraz; Fuller, Franklin D.; Kim, In-Sik; Cheah, Mun Hon; Fransson, Thomas; Bhowmick, Asmit; Young, Iris D.; O'Riordan, Lee; Brewster, Aaron S.; Pettinati, Ilaria; Doyle, Margaret; Joti, Yasumasa; Owada, Shigeki; Tono, Kensuke; Batyuk, Alexander; Hunter, Mark S.; Alonso-Mori, Roberto; Bergmann, Uwe; Owen, Robin L.; Sauter, Nicholas K.; Claridge, Timothy D. W.; Robinson, Carol V.; Yachandra, Vittal K.; Yano, Junko; Kern, Jan F.; Orville, Allen M.; Schofield, Christopher J.
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
NATURE COMMUNICATIONS
IF15.7
2021-07-2241
OAAI
Butryn, Agata; Simon, Philipp S.; Aller, Pierre; Hinchliffe, Philip; Massad, Ramzi N.; Leen, Gabriel; Tooke, Catherine L.; Bogacz, Isabel; Kim, In-Sik; Bhowmick, Asmit; Brewster, Aaron S.; Devenish, Nicholas E.; Brem, Jurgen; Kamps, Jos J. A. G.; Lang, Pauline A.; Rabe, Patrick; Axford, Danny; Beale, John H.; Davy, Bradley; Ebrahim, Ali; Orlans, Julien; Storm, Selina L. S.; Zhou, Tiankun; Owada, Shigeki; Tanaka, Rie; Tono, Kensuke; Evans, Gwyndaf; Owen, Robin L.; Houle, Frances A.; Sauter, Nicholas K.; Schofield, Christopher J.; Spencer, James; Yachandra, Vittal K.; Yano, Junko; Kern, Jan F.; Orville, Allen M.
High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2020-07-2043
OAAI
Srinivas, Vivek; Banerjee, Rahul; Lebrette, Hugo; Jones, Jason C.; Aurelius, Oskar; Kim, In-Sik; Pham, Cindy C.; Gul, Sheraz; Sutherlin, Kyle D.; Bhowmick, Asmit; John, Juliane; Bozkurt, Esra; Fransson, Thomas; Aller, Pierre; Butryn, Agata; Bogacz, Isabel; Simon, Philipp; Keable, Stephen; Britz, Alexander; Tono, Kensuke; Kim, Kyung Sook; Park, Sang-Youn; Lee, Sang Jae; Park, Jaehyun; Alonso-Mori, Roberto; Fuller, Franklin D.; Batyuk, Alexander; Brewster, Aaron S.; Bergmann, Uwe; Sauter, Nicholas K.; Orville, Allen M.; Yachandra, Vittal K.; Yano, Junko; Lipscomb, John D.; Kern, Jan; Hogbom, Martin
Untangling the sequence of events during the S2 → S3 transition in photosystem II and implications for the water oxidation mechanism
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-05-20175
OAAI
Ibrahim, Mohamed; Fransson, Thomas; Chatterjee, Ruchira; Cheah, Mun Hon; Hussein, Rana; Lassalle, Louise; Sutherlin, Kyle D.; Young, Iris D.; Fuller, Franklin D.; Gul, Sheraz; Kim, In-Sik; Simon, Philipp S.; de Lichtenberg, Casper; Chernev, Petko; Bogacz, Isabel; Pham, Cindy C.; Orville, Allen M.; Saichek, Nicholas; Northen, Trent; Batyuk, Alexander; Carbajo, Sergio; Alonso-Mori, Roberto; Tono, Kensuke; Owada, Shigeki; Bhowmick, Asmit; Bolotovsky, Robert; Mendez, Derek; Moriarty, Nigel W.; Holton, James M.; Dobbek, Holger; Brewster, Aaron S.; Adams, Paul D.; Sauter, Nicholas K.; Bergmann, Uwe; Zouni, Athina; Messinger, Johannes; Kern, Jan; Yachandra, Vittal K.; Yano, Junko
Photoreversible interconversion of a phytochrome photosensory module in the crystalline state
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-12-1820
OAAI
Burgie, E. Sethe; Clinger, Jonathan A.; Miller, Mitchell D.; Brewster, Aaron S.; Aller, Pierre; Butryn, Agata; Fuller, Franklin D.; Gul, Sheraz; Young, Iris D.; Pham, Cindy C.; Kim, In-Sik; Bhowmick, Asmit; O'Riordan, Lee J.; Sutherlin, Kyle D.; Heinemann, Joshua V.; Batyuk, Alexander; Alonso-Mori, Roberto; Hunter, Mark S.; Koglin, Jason E.; Yano, Junko; Yachandra, Vittal K.; Sauter, Nicholas K.; Cohen, Aina E.; Kern, Jan; Orville, Allen M.; Phillips, George N., Jr.; Vierstra, Richard D.

研究方向

暂未获取到该数据
A
Asmit Bhowmick
H 指数:21论文数:82被引数:1,604
J
Jan Kern
H 指数:50论文数:242被引数:1.4万
A
Aaron S. Brewster
H 指数:41论文数:223被引数:7,791
J
Junko Yano
H 指数:84论文数:521被引数:2.6万
N
Nicholas K. Sauter
H 指数:54论文数:265被引数:1.7万
V
Vittal K. Yachandra
H 指数:70论文数:291被引数:1.8万
F
Franklin D. Fuller
H 指数:26论文数:88被引数:3,749
S
Sheraz Gul
H 指数:42论文数:142被引数:8,738
A
Allen M. Orville
H 指数:39论文数:194被引数:5,524
A
A. Batyuk
H 指数:26论文数:119被引数:3,246