Peter Orchard - Publications, H-index & Citations

Peter Orchard

university of michigan

15H指数

95论文数

1.1K被引数

收录论文 31

发表时间

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed TOPMed中表达和剪接数量性状位点的跨队列分析

Science

IF45.8

2026-07-16

PREAI

Peter Orchard; Thomas W. Blackwell; Linda Kachuri; Peter J. Castaldi; Michael H. Cho; Stephanie A. Christenson; Peter Durda; Stacey Gabriel; Craig P. Hersh; Scott Huntsman; Seungyong Hwang; Roby Joehanes; Mari Johnson; Xingnan Li; Honghuang Lin; Ching-Ti Liu; Yongmei Liu; Angel C. Y. Mak; Ani W. Manichaikul; David T. Paik; Aabida Saferali; Joshua D. Smith; Kent D. Taylor; Russell P. Tracy; Jiongming Wang; Mingqiang Wang; Joshua S. Weinstock; Jeffrey Weiss; Heather E. Wheeler; Ying Zhou; Sebastian Zöllner; Joseph C. Wu; Luisa Mestroni; Sharon Graw; Matthew R. G. Taylor; Victor E. Ortega; W. Craig Johnson; Weiniu Gan; Goncalo Abecasis; Deborah A. Nickerson; Namrata Gupta; Kristin Ardlie; Prescott G. Woodruff; Russell P. Bowler; Deborah A. Meyers; Alex Reiner; Charles Kooperberg; Elad Ziv; Ramachandran S. Vasan; Martin G. Larson; L. Adrienne Cupples; Edwin K. Silverman; Stephen S. Rich; Nancy Heard-Costa; Hua Tang; Jerome I. Rotter; Albert V. Smith; Daniel Levy; ; ; François Aguet; Laura J. Scott; Laura M. Raffield; Stephen C. J. Parker

Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants 44,287名多血统受试者肺功能和COPD的全基因组序列分析

Genome Biology

IF9.4

2026-01-15

OAAI

Wonji Kim; Xiaowei Hu; Kangjin Kim; Sung Chun; Peter Orchard; Dandi Qiao; Ingo Ruczinski; Aabida Saferali; Francois Aguet; Lucinda Antonacci-Fulton; Pallavi P. Balte; Traci M. Bartz; Wardatul Jannat Anamika; Xiaobo Zhou; JunYi Duan; Jennifer A. Brody; Brian E. Cade; Martha L. Daviglus; Harshavadran Doddapaneni; Shannon Dugan-Perez; Susan K. Dutcher; Christian D. Frazar; Stacey B. Gabriel; Sina A. Gharib; Namrata Gupta; Brian D. Hobbs; Silva Kasela; Laura R. Loehr; Ginger A. Metcalf; Donna M. Muzny; Elizabeth C. Oelsner; Laura J. Rasmussen-Torvik; Colleen M. Sitlani; Joshua Smith; Tamar Sofer; Hanfei Xu; Bing Yu; David Zhang; John Ziniti; R. Graham Barr; April P. Carson; Myriam Fornage; Lifang Hou; Ravi Kalhan; Robert Kaplan; Tuuli Lappalainen; Stephanie J. London; Alanna C. Morrison; George T. O’Connor; Bruce M. Psaty; Laura M. Raffield; Susan Redline; Stephen S. Rich; Jerome I. Rotter; Edwin K. Silverman; Ani Manichaikul; Michael H. Cho

Whole Blood Transcriptomic Analysis of Sickle Cell Trait 镰状细胞特异性的全血转录组分析

EUROPEAN JOURNAL OF HAEMATOLOGY

IF2.3

2026-01-01

OAAI

Johnson, Mari; Cai, Yanwei; Vasconcelos, Ana Gabriela; Orchard, Peter; Auer, Paul L.; Lettre, Guillaume; Wen, Jia; Franceschini, Nora; Kooperberg, Charles; Sun, Wei; Hsu, Li; Raffield, Laura M.; Reiner, Alex P.

CelLink: integrating single-cell multi-omics data with weak feature linkage and imbalanced cell populations CelLink：整合单细胞多组学数据，并处理弱特征关联和不平衡细胞群体

NUCLEIC ACIDS RESEARCH

IF13.1

2025-12-11

OAAI

Luo, Xin; Huang, Yuanhao; Zeng, Haoxuan; Tao, Yicheng; Bao, Xinyu; Feng, Fan; Hopkirk, Alexander l; Pham, Thai; Bate, Thomas S. R.; Saunders, Diane C.; Orchard, Peter; Robertson, Cassie; Shrestha, Shristi; Spraggins, Jeffrey M.; Cartailler, Jean-Philippe; Parker, Stephen c J.; Brissova, Marcela; Liu, Jie

Integrating whole genome and transcriptome sequencing to characterize the genetic architecture of isoform variation 整合全基因组与转录组测序以表征异构体变异的遗传结构

Nature Communications

IF15.7

2025-11-22

OAAI

Chunyu Liu; Roby Joehanes; Jiantao Ma; Jiuyong Xie; Jian Yang; Mengyao Wang; Tianxiao Huan; Shih-Jen Hwang; Jia Wen; Quan Sun; Cumhur Y. Demirkale; Nancy L. Heard-Costa; Peter Orchard; April P. Carson; Jeffrey W. Haessler; Laura M. Raffield; Alex P. Reiner; Nora Franceschini; Paul L. Auer; Charles Kooperberg; Yun Li; George O’Connor; Joanne M. Murabito; Peter Munson; Daniel Levy

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals 整合性单细胞多组学分析人类胰腺胰岛，鉴定1型糖尿病相关基因及调控信号

Cell Reports

IF6.9

2025-07-29

OAAI

Ricardo D'Oliveira Albanus; Xiaoshan Zhang; Zeping Zhao; Henry J. Taylor; Xuming Tang; Yuling Han; Peter Orchard; Arushi Varshney; Tuo Zhang; Nandini Manickam; Michael R. Erdos; Narisu Narisu; Leland Taylor; Xiaxia Saavedra; Xinyi Liu; Aaron Zhong; Bo Li; Ting Zhou; Ali Naji; Chengyang Liu; Francis S. Collins; Stephen C.J. Parker; Shuibing Chen

Extensive differential gene expression and regulation by sex in human skeletal muscle 性別对人类骨骼肌广泛差异基因表达和调控的影响

Cell Genomics

IF9

2025-06-05

OAAI

Sarah C. Hanks; Abigail S. Mauger; Arushi Varshney; Dan L. Ciotlos; Nandini Manickam; Narisu Narisu; Alexandria J. Shumway; Peter Orchard; Michael R. Erdos; Michael D. Sweeney; Jeffrey Okamoto; Anne U. Jackson; Heather M. Stringham; Lori L. Bonnycastle; Xiang Zhou; Timo A. Lakka; Karen L. Mohlke; Jaakko Tuomilehto; Markku Laakso; Michael Boehnke; Praveen Sethupathy; Francis S. Collins; Heikki A. Koistinen; Stephen C.J. Parker; Laura J. Scott

Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood 血液中嵌合体Y染色体缺失的基因组与表型相关性

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2025-02-01

OAAI

Jakubek, YA; Ma, XL; Stilp, AM; Yu, FL; Bacon, J; Wong, JW; Aguet, F; Ardlie, K; Arnett, DK; Barnes, K; Bis, JC; Blackwell, T; Becker, LC; Boerwinkle, E; Bowler, RP; Budoff, MJ; Carson, AP; Chen, JW; Cho, MH; Coresh, J; Cox, NJ; Vries, PSD; Demeo, DL; Fardo, DW; Fornage, M; Guo, XQ; Hall, ME; Heard-Costa, N; Hidalgo, B; Irvin, MR; Johnson, AD; Jorgenson, E; Kenny, EE; Kessler, MD; Levy, D; Li, Y; Lima, JAC; Liu, YM; Locke, AE; Loos, RJF; Machiela, MJ; Mathias, RA; Mitchell, BD; Murabito, JM; Mychaleckyj, JC; North, KE; Orchard, P; Parker, SCJ; Pershad, Y; Peyser, PA; Pratte, KA; Psaty, BM; Raffield, LM; Redline, S; Rich, SS; Rotter, JI; Shah, SJ; Smith, JA; Smith, AP; Smith, A; Taub, MA; Tiwari, HK; Tracy, R; Tuftin, B; Bick, AG; Sankaran, VG; Reiner, AP; Scheet, P; Auer, PL

Evidence for compensatory evolution within pleiotropic regulatory elements

GENOME RESEARCH

IF5.5

2024-09-10

OAAI

Kliesmete, Zane; Orchard, Peter; Lee, Victor Yan Kin; Geuder, Johanna; Krauss, Simon M.; Ohnuki, Mari; Jocher, Jessica; Vieth, Beate; Enard, Wolfgang; Hellmann, Ines

Previously Frozen Beta-Cell Transcriptional Response to Cytokine Treatment Mirrors That of Fresh Beta Cells

DIABETES

IF7.5

2024-06-14

PREAI

Orchard, Peter; Wang, Xiaoou; Yan, Tingfen; Narisu, Narisu; Robertson, Cassie; Erdos, Michael; Meng, Jerry; Collins, Francis S.; Chen, Shuibing; Parker, Stephen C.

Optimization of Single Nuclei Isolation from Frozen Human Skeletal Muscle and Pancreatic Tissue Samples for Single Nuclei Multiome ATAC plus Gene Expression

DIABETES

IF7.5

2024-06-14

PREAI

Dolgachev, Vladislav; Varshney, Arushi; Moo, Keagan G.; Wang, Xiaoou; Orchard, Peter; Saunders, Diane C.; Brissova, Marcela; Parker, Stephen C.

ADA Presidents' Select Abstract: Discovering Stimulatory State-Specific Type 2 Diabetes GWAS Mechanisms with Single-Cell Multiomics on iPSC-Derived Fibro-adipogenic Progenitor Cell Villages

DIABETES

IF7.5

2024-06-14

PREAI

Ventresca, Christa; Varshney, Arushi; Orchard, Peter; Tsan, Yao-Chang; Da Rocha, Andre Monteiro; Laakso, Markku, Sr.; Tuomilehto, Jaakko; Lakka, Timo A.; Mohlke, Karen L.; Boehnke, Michael; Scott, Laura; Koistinen, Heikki A.; Collins, Francis S.; Herron, Todd J.; Bielas, Stephanie; Parker, Stephen

Type 2 Diabetes GWAS Signal C2CD4A/B Insulin Resistance Mechanisms in Skeletal Muscle

DIABETES

IF7.5

2024-06-14

PREAI

Epelle, Ibiere L.; Varshney, Arushi; Orchard, Peter; Zhang, Zhenhao; Feng, Fan; Laakso, Markku, Sr.; Tuomilehto, Jaakko; Lakka, Timo A.; Mohlke, Karen L.; Boehnke, Michael; Scott, Laura; Koistinen, Heikki A.; Collins, Francis S.; Liu, Jie; Parker, Stephen C.

Multiome Profiling of Human Islets Nominates Beta-CellSpecific Cytokine Response Profiles Underlying Type 1 Diabetes

DIABETES

IF7.5

2024-06-14

PREAI

Robertson, Cassie; Wang, Xiaoou; Orchard, Peter; Meng, Jerry; Dolgachev, Vladislav; Manickam, Nandini; Narisu, Narisu; Erdos, Michael; Collins, Francis S.; Chen, Shuibing; Parker, Stephen C.

Single-Nucleus Multiomics Profiling across 49 Individuals of Hispanic Ancestry Reveals Cell-Specific Skeletal Muscle Insulin-Responsive Gene Regulatory Signatures

DIABETES

IF7.5

2024-06-14

PREAI

Li, Benjamin; Varshney, Arushi; Tovar, Adelaide; Manickam, Nandini; Orchard, Peter; Defronzo, Ralph A.; Norton, Luke; Parker, Stephen

Differential Cell-Type-Specific Gene Expression and Chromatin Accessibility by Type 2 Diabetes Status and Physical Activity Levels in Human Skeletal Muscle

DIABETES

IF7.5

2024-06-14

PREAI

Ciotlos, Dan; Hanks, Sarah; Varshney, Arushi; Erdos, Michael; Manickam, Nandini; Stringham, Heather M.; Hill-Burns, Erin; Orchard, Peter; Narisu, Narisu; Bonnycastle, Lori L.; Sweeney, Michael D.; Laakso, Markku, Sr.; Tuomilehto, Jaakko; Lakka, Timo A.; Mohlke, Karen L.; Boehnke, Michael; Koistinen, Heikki A.; Collins, Francis S.; Parker, Stephen; Scott, Laura

Population-Scale Skeletal Muscle Single-Nucleus Multiomic Profiling Reveals Extensive Context-Specific Genetic Regulation

DIABETES

IF7.5

2024-06-14

PREAI

Varshney, Arushi; Manickam, Nandini; Orchard, Peter; Tovar, Adelaide; Zhang, Zhenhao; Feng, Fan; Lakka, Timo A.; Laakso, Markku, Sr.; Tuomilehto, Jaakko; Mohlke, Karen L.; Kitzman, Jacob; Koistinen, Heikki A.; Liu, Jie; Boehnke, Michael; Collins, Francis S.; Scott, Laura; Parker, Stephen C.

Widespread Age-Associated Changes in the Chromatin Architecture of Skeletal Muscle Cell Types

DIABETES

IF7.5

2024-06-14

PREAI

Moo, Keagan G.; Albanus, Ricardo D'Oliveira; Varshney, Arushi; Orchard, Peter; Manickam, Nandini; Laakso, Markku, Sr.; Tuomilehto, Jaakko; Lakka, Timo A.; Mohlke, Karen L.; Boehnke, Michael; Scott, Laura; Koistinen, Heikki A.; Collins, Francis S.; Parker, Stephen

FixItFelix: improving genomic analysis by fixing reference errors

GENOME BIOLOGY

IF9.4

2023-02-21

OAAI

Behera, Sairam; LeFaive, Jonathon; Orchard, Peter; Mahmoud, Medhat; Paulin, Luis F.; Farek, Jesse; Soto, Daniela C.; Parker, Stephen C. J.; Smith, Albert V.; Dennis, Megan Y.; Zook, Justin M.; Sedlazeck, Fritz J.

Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data 全面的增强子-靶基因分配改善了全基因组调控数据的基因集水平解释

GENOME BIOLOGY

IF9.4

2022-04-26

OAAI

Qin, Tingting; Lee, Christopher; Li, Shiting; Cavalcante, Raymond G.; Orchard, Peter; Yao, Heming; Zhang, Hanrui; Wang, Shuze; Patil, Snehal; Boyle, Alan P.; Sartor, Maureen A.

研究方向