未登录Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation上皮转录因子GRHL2的去抑制促进了直接的肝细胞到胆管细胞的转分化
Vasseur, Ludivine; Gheeraert, Celine; Dubois-Chevalier, Julie; Very, Ninon; Guille, Loic; Bou Saleh, Mohamed; Boulet, Clemence; Sobolewski, Cyril; Loyer, Pascal; Berthier, Alexandre; Legrand, Noemie; Corlu, Anne; Gnemmi, Viviane; Lasailly, Guillaume; Leteurtre, Emmanuelle; Galinousky, Dmitry; Bongiovanni, Antonino; Taront, Solenne; Toft, Nicolaj I.; Grontved, Lars; Tulasne, David; Furlan, Alessandro; Ntandja-Wandji, Line Carolle; Staels, Bart; Lefebvre, Philippe; Dubuquoy, Laurent; Eeckhoute, Jerome
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收藏A coregulatory influence map of glioblastoma heterogeneity and plasticity胶质母细胞瘤异质性和可塑性的共调控影响图谱
Bernhard, Chloe; Geles, Konstantinos; Pawlak, Geoffrey; Dhifli, Wajdi; Dispot, Aurelien; Dusol, Jules; Kondratova, Maria; Martin, Sophie; Messe, Melissa; Reita, Damien; Tulasne, David; Van Seuningen, Isabelle; Entz-Werle, Natacha; Ciafre, Silvia Anna; Dontenwill, Monique; Elati, Mohamed
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收藏MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation
Guerin, Celia; Vinchent, Audrey; Fernandes, Marie; Damour, Isabelle; Laratte, Agathe; Tellier, Remi; Estevam, Gabriella O.; Meneboo, Jean-Pascal; Villenet, Celine; Descarpentries, Clotilde; Fraser, James S.; Figeac, Martin; Cortot, Alexis B.; Rouleau, Etienne; Tulasne, David
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收藏Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression受体酪氨酸激酶MET与ETS转录因子功能相互作用促进前列腺癌进展
Carouge, Elisa; Burnichon, Clemence; Figeac, Martin; Sebda, Sheherazade; Vanpouille, Nathalie; Vinchent, Audrey; Truong, Marie-Jose; Duterque-Coquillaud, Martine; Tulasne, David; Chotteau-Lelievre, Anne
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收藏Transforming properties of MET receptor exon 14 skipping can be recapitulated by loss of the CBL ubiquitin ligase binding site
Fernandes, Marie; Paget, Sonia; Kherrouche, Zoulika; Truong, Marie-Jose; Vinchent, Audrey; Meneboo, Jean-Pascal; Sebda, Sheherazade; Werkmeister, Elisabeth; Descarpentries, Clotilde; Figeac, Martin; Cortot, Alexis B.; Tulasne, David
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收藏MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)-dependent oncogenic driver in vitro and in humanised HGF knock-in miceMET外显子14跳跃突变是体外和人源化HGF敲入小鼠中肝细胞生长因子 (HGF) 依赖性致癌驱动因子
Fernandes, Marie; Hoggard, Brynna; Jamme, Philippe; Paget, Sonia; Truong, Marie-Jose; Gregoire, Valerie; Vinchent, Audrey; Descarpentries, Clotilde; Morabito, Angela; Stanislovas, Justas; Farage, Enoir; Meneboo, Jean-Pascal; Sebda, Sheherazade; Bouchekioua-Bouzaghou, Katia; Nollet, Marie; Humez, Sarah; Perera, Timothy; Fromme, Paul; Grumolato, Luca; Figeac, Martin; Copin, Marie-Christine; Tulasne, David; Cortot, Alexis B.; Kermorgant, Stephanie; Kherrouche, Zoulika
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收藏Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage
Tulasne, D; Deheuninck, J; Lourenco, FC; Lamballe, F; Ji, ZL; Leroy, C; Puchois, E; Moumen, A; Maina, F; Mehlen, P; Fafeur, V
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收藏Novel germline MET pathogenic variants in French patients with papillary renal cell carcinomas type I法国I型乳头状肾细胞癌患者的新种系MET致病变异
Sebai, Molka; Tulasne, David; Caputo, Sandrine M.; Verkarre, Virginie; Fernandes, Marie; Guerin, Celia; Reinhart, Fanny; Adams, Severine; Maugard, Christine; Caron, Olivier; Guillaud-Bataille, Marine; Berthet, Pascaline; Bignon, Yves-Jean; Bressac-de Paillerets, Brigitte; Burnichon, Nelly; Chiesa, Jean; Giraud, Sophie; Lejeune, Sophie; Limacher, Jean-Marc; de Pauw, Antoine; Stoppa-Lyonnet, Dominique; Zattara-Cannoni, Helene; Deveaux, Sophie; Lidereau, Rosette; Richard, Stephane; Rouleau, Etienne
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收藏MET exon 14 skipping mutations in lung cancer: Screening, functional and clinical impact
Fernandes, Marie; Jamme, Philippe; Paget, Sonia; Morabito, Angela; Lepretre, Frederic; Figeac, Martin; Descarpentries, Clotilde; Escande, Fabienne; Baldacci, Simon; Chotteau-Lelievre, Anne; Grumolato, Luca; Copin, Marie-Christine; Kherrouche, Zoulika; Cortot, Alexis B.; Tulasne, David
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收藏2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations
Trzaska, Carole; Amand, Severine; Bailly, Christine; Leroy, Catherine; Marchand, Virginie; Duvernois-Berthet, Evelyne; Saliou, Jean-Michel; Benhabiles, Hana; Werkmeister, Elisabeth; Chassat, Thierry; Guilbert, Romain; Hannebique, David; Mouray, Anthony; Copin, Marie-Christine; Moreau, Pierre-Arthur; Adriaenssens, Eric; Kulozik, Andreas; Westhof, Eric; Tulasne, David; Motorin, Yuri; Rebuffat, Sylvie; Lejeune, Fabrice
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收藏Control of cell death/survival balance by the MET dependence receptor
Duplaquet, Leslie; Leroy, Catherine; Vinchent, Audrey; Paget, Sonia; Lefebvre, Jonathan; Vanden Abeele, Fabien; Lancel, Steve; Giffard, Florence; Paumelle, Rejane; Bidaux, Gabriel; Heliot, Laurent; Poulain, Laurent; Furlan, Alessandro; Tulasne, David
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收藏Gemcitabine-induced epithelial-mesenchymal transition-like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal-like phenotype
El Amrani, Mehdi; Corfiotti, Francois; Corvaisier, Matthieu; Vasseur, Romain; Fulbert, Maxence; Skrzypczyk, Cecile; Deshorgues, Anne-Claire; Gnemmi, Viviane; Tulasne, David; Lahdaoui, Fatima; Vincent, Audrey; Pruvot, Francois-Rene; Van Seuningen, Isabelle; Huet, Guillemette; Truant, Stephanie
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收藏Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer
Duplaquet, Leslie; Figeac, Martin; Lepretre, Frederic; Frandemiche, Charline; Villenet, Celine; Sebda, Sheherazade; Sarafan-Vasseur, Nasrin; Benozene, Melanie; Vinchent, Audrey; Goormachtigh, Gautier; Wicquart, Laurence; Rousseau, Nathalie; Beaussire, Ludivine; Truant, Stephanie; Michel, Pierre; Sabourin, Jean-Christophe; Galateau-Salle, Francoise; Copin, Marie-Christine; Zalcman, Gerard; De Launoit, Yvan; Fafeur, Veronique; Tulasne, David
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收藏Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes
Gnangnon, Benedicte; Freville, Aline; Cailliau, Katia; Leroy, Catherine; De Witte, Caroline; Tulasne, David; Martoriarti, Alain; Jung, Vincent; Guerrera, Ida Chiara; Marion, Sabrina; Khalife, Jamal; Pierrot, Christine
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