未登录 BMN 349, a small molecule inhibitor of Z alpha-1 antitrypsin polymerization, increases secretion and reduces intrahepatic inclusions in a mouse model of disease BMN 349，一种Z α-1抗胰蛋白酶聚合的小分子抑制剂，可增加分泌并减少疾病小鼠模型中的肝内包涵体 Handyside, Britta; Wenzel, Heather; Mackenzie, Donald; Chang, Catherine; Greenslade, Annie; Van Vleet, Jeremy; Heglar, Brian; Chen, Joseph C.; Zhang, Lening; Larimore, Kevin; Zhou, Huiyu; Trantcheva, Iva; Sims, Lawrence; Evans, Kristin; Fong, Sylvia; Kumar, Gyanendra; Annu, Kavya; Ronzoni, Riccardo; Irving, James A.; Wang, Bing; Bunting, Stuart; Lomas, David A. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Sinorhizobium meliloti BR-bodies promote fitness during host colonization Mallikaarachchi, Kaveendya S.; Huang, Jason L.; Madras, Shanmukha; Cuellar, Rodrigo A.; Huang, Zhenzhong; Gega, Alisa; Rathnayaka-Mudiyanselage, Imalka W.; Nandana, Vidhyadhar; Al-Husini, Nadra; Saldana-Rivera, Natalie; Ma, Loi H.; Ng, Eric; Christensen, Klara; Pendar, Nima; Li, Sophia; Deleon, Nayeli Rodas; Chen, Joseph C.; Schrader, Jared M. 分享 收藏
Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model 脑室内给予一种改良的己糖胺酶可改善GM2小鼠模型的晚期神经退行性病变 Lopez, Manuel E.; Wendt, Daniel; Lawrence, Roger; Gong, Kerui; Ong, Hoonsan; Yip, Bryan; Chen, Joseph; Mangini, Linley; Handyside, Britta; Giaramita, Alexander; Lamichhane, Aashish; Lo, Melanie; Agrawal, Vishal; Van Vleet, Jeremy; Abolhesn, Amanda; Felix, Jessica B.; Villalpando, Isaac; Bhat, Vikas; De Angelis, Rolando; Ru, Yuanbin; Khan, Ayesha; Fong, Sylvia; Christianson, Terri; Bullens, Sherry; Crawford, Brett E.; Bunting, Stuart; Aoyagi-Scharber, Mika 分享 收藏
An engineered β-galactosidase with improved stability and crosscorrection for the potential treatment of GM1 Gangliosidosis via AAV gene therapy Reddy, Charu; Onguka, Ouma; Artz, Jacob; Schmitt, Christopher; Grossman, Adam; Santosh, Swetha; Akinkugbe, Oluwayomi; Wong, Victoria; Gebretsadik, Kahsay; Sedighi, Faezeh; Tang, Jinyan; Del Greco, Elizabeth; Lee, Grace S.; Kruse, Nikki; Chng, Chinping; Duan, Da; Hallows, William C.; Chen, Joseph C.; Akeefe, Hassibullah; Silverman, Adam P.; Huisman, Gjalt 分享 收藏
In vitro modeling of GM1 gangliosidosis using iPSC-derived cellular and organoid CNS models Schmitt, Christopher E.; Lee, Grace S.; Onguka, Ouma; Wong, Victoria; Del Greco, Elizabeth; Sedighi, Faezeh; Reddy, Charu; Santosh, Swetha; Akinkugbe, Oluwayomi; Artz, Jacob; Kruse, Nikki; Chng, Chinping; Hallows, William C.; Chen, Joseph C.; Akeefe, Hassibullah; Silverman, Adam P.; Huisman, Gjalt 分享 收藏
Intracerebroventricular enzyme replacement therapy with β-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice Chen, Joseph C.; Luu, Amanda R.; Wise, Nathan; De Angelis, Rolando; Agrawal, Vishal; Mangini, Linley; Vincelette, Jon; Handyside, Britta; Sterling, Harry; Lo, Melanie J.; Wong, Hio; Galicia, Nicole; Pacheco, Glenn; Van Vleet, Jeremy; Giaramita, Alexander; Fong, Sylvia; Roy, Sushmita M.; Hague, Chuck; Lawrence, Roger; Bullens, Sherry; Christianson, Terri M.; d'Azzo, Alessandra; Crawford, Brett E.; Bunting, Stuart; LeBowitz, Jonathan H.; Yogalingam, Gouri 分享 收藏
Iron Supplementation Eliminates Antagonistic Interactions Between Root-Associated Bacteria Eng, Thomas; Herbert, Robin A.; Martinez, Uriel; Wang, Brenda; Chen, Joseph C.; Brown, James B.; Deutschbauer, Adam M.; Bissell, Mina J.; Mortimer, Jenny C.; Mukhopadhyay, Aindrila 分享 收藏
Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-II signaling George, Ashley F.; Jang, Karen S.; Nyegaard, Mette; Neidleman, Jason; Spitzer, Trimble L.; Xie, Guorui; Chen, Joseph C.; Herzig, Eytan; Laustsen, Anders; de Menezes, Erika G. Marques; Houshdaran, Sahar; Pilcher, Christopher D.; Norris, Philip J.; Jakobsen, Martin R.; Greene, Warner C.; Giudice, Linda C.; Roan, Nadia R. 分享 收藏
Rhizobacteria mediate the phytotoxicity of a range of biorefinery-relevant compounds Herbert, Robin A.; Eng, Thomas; Martinez, Uriel; Wang, Brenda; Langley, Sasha; Wan, Kenneth; Pidatala, Venkataramana; Hoffman, Elijah; Chen, Joseph C.; Bissell, Mina J.; Brown, James B.; Mukhopadhyay, Aindrila; Mortimer, Jenny C. 分享 收藏
Jungle Express is a versatile repressor system for tight transcriptional control (vol 9, 3617, 2018) Ruegg, Thomas L.; Pereira, Jose H.; Chen, Joseph C.; DeGiovanni, Andy; Novichkov, Pavel; Mutalik, Vivek K.; Tomaleri, Giovani P.; Singer, Steven W.; Hillson, Nathan J.; Simmons, Blake A.; Adams, Paul D.; Thelen, Michael P. 分享 收藏
Jungle Express is a versatile repressor system for tight transcriptional control Ruegg, Thomas L.; Pereira, Jose H.; Chen, Joseph C.; DeGiovanni, Andy; Novichkov, Pavel; Mutalik, Vivek K.; Tomaleri, Giovani P.; Singer, Steven W.; Hillson, Nathan J.; Simmons, Blake A.; Adams, Paul D.; Thelen, Michael P. 分享 收藏
分享 收藏
分享 收藏
Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+T cells Neidleman, Jason A.; Chen, Joseph C.; Kohgadai, Nargis; Muller, Janis A.; Laustsen, Anders; Thavachelvam, Karthiga; Jang, Karen S.; Sturzel, Christina M.; Jones, Jennifer J.; Ochsenbauer, Christina; Chitre, Avantika; Somsouk, Ma; Garcia, Maurice M.; Smith, James F.; Greenblatt, Ruth M.; Munch, Jan; Jakobsen, Martin R.; Giudice, Linda C.; Greene, Warner C.; Roan, Nadia R. 分享 收藏
分享 收藏
分享 收藏
Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis Barragan, Fatima; Irwin, Juan C.; Balayan, Shaina; Erikson, David W.; Chen, Joseph C.; Houshdaran, Sahar; Piltonen, Terhi T.; Spitzer, Trimble L. B.; George, Ashley; Rabban, Joseph T.; Nezhat, Camran; Giudice, Linda C. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
