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Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach Mandhair, Harpreet K.; Radpour, Ramin; Westerhuis, Mira; Banz, Yara; Humbert, Magali; Arambasic, Miroslav; Dengjel, Joern; Davies, Andrew; Tschan, Mario P.; Novak, Urban 分享 收藏
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TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape Pied, Noemie; Daussy, Coralie F.; Denis, Zoe; Ragues, Jessica; Faure, Muriel; Iggo, Richard; Tschan, Mario P.; Roger, Benoit; Rayne, Fabienne; Wodrich, Harald 分享 收藏
Intracellular Proprotein convertase subtilisin/kexin type 9: Recruitment and regulatory role in mitochondrial architecture and bioenergetic Gavini, J.; Leuenberger, D.; Yarahmadov, T.; Dommann, N.; Keogh, A.; Melin, N.; Tschan, M.; Nuoffer, J-M; Hertig, D.; Zuber, B.; Odriozola, A.; Tombolini, R.; Chretien, M.; Mbikay, M.; Candinas, D.; Stroka, D. 分享 收藏
Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schlafli, Anna M.; Krauer, Deborah; Federzoni, Elena A.; Vu, Bich; Moresco, James J.; Yates, John R., III; Sadowski, Martin C.; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P.; Torbett, Bruce E. 分享 收藏
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia Gianni, Maurizio; Goracci, Laura; Schlaefli, Anna; Di Veroli, Alessandra; Kurosaki, Mami; Guarrera, Luca; Bolis, Marco; Foglia, Marika; Lupi, Monica; Tschan, Mario P.; Cruciani, Gabriele; Terao, Mineko; Garattini, Enrico 分享 收藏
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Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Eric; Konstantinidou, Georgia; Tschan, Mario; Hegedus, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M.; Kocher, Gregor J.; Wang, Wenxiang; Schmid, Ralph A.; Peng, Ren-Wang 分享 收藏
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Role of Hexokinase 2 and 3 in Energy Metabolism, Myeloid Differentiation and Cancer Development Seiler, Kristina; Minder, Petra; Mashimo, Iris; Humbert, Magali; Federzoni, Elena; Moresco, James; Yates, John; Tschan, Mario; Torbett, Bruce 分享 收藏
Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot Humbert, Magali; Moran, Maria; de la Cruz-Ojeda, Patricia; Muntane, Jordi; Wiedmer, Tabea; Apostolova, Nadezda; McKenna, Sharon L.; Velasco, Guillermo; Balduini, Walter; Eckhart, Leopold; Janji, Bassam; Sampaio-Marques, Belem; Ludovico, Paula; Zerovnik, Eva; Langer, Rupert; Perren, Aurel; Engedal, Nikolai; Tschan, Mario P. 分享 收藏
Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma Viteporfin诱导的溶酶体区室失调增强了索拉非尼在肝细胞癌中的作用 Gavini, Jacopo; Dommann, Noelle; Jakob, Manuel O.; Keogh, Adrian; Bouchez, Laure C.; Karkampouna, Sofia; Kruithof-de Julio, Marianna; Medova, Michaela; Zimmer, Yitzhak; Schlaefli, Anna M.; Tschan, Mario P.; Candinas, Daniel; Stroka, Deborah; Banz, Vanessa 分享 收藏
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CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway CDX2在结直肠癌中是独立的预后因素,在锯齿状通路的肿瘤中受启动子甲基化和组蛋白去乙酰化的调控 Graule, Janina; Uth, Kristin; Fischer, Elia; Centeno, Irene; Galvan, Jose A.; Eichmann, Micha; Rau, Tilman T.; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin D.; Schnuriger, Beat; Hadrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario P.; Zlobec, Inti 分享 收藏