Hong-Shuo Sun

University of Toronto

H指数:43

被引数:5,089

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Natural product-derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

天然产物衍生的TRPM7通道抑制剂在神经损伤中的作用：机制、药理潜力及转化挑战

British Journal of Pharmacology

IF7.7

2026-09-190

OAAI

TRPM7 kinase: a target for multimodal drug development in neurological disorders

TRPM7激酶：神经系统疾病中多模式药物开发的靶点

Acta Pharmacologica Sinica

IF8.4

2026-05-260

PRE

A neutrophil-intrinsic CKLF1–PKM2 axis drives glycolytic flux for de novo DAG synthesis and pro-inflammatory ROS production

中性粒细胞内源性CKLF1–PKM2轴驱动糖酵解流以促进从头二酰基甘油合成和促炎ROS产生

cell death & differentiation

IF0

2026-05-120

PRE

SNAP-23 mediated vesicular trafficking in oligodendrocytes is necessary to maintain adult myelin integrity in mice

SNAP-23介导的少突胶质细胞囊泡转运对维持小鼠成年期髓鞘完整性是必需的

Nature Communications

IF15.7

2026-05-010

PRE

TRPM7 kinase inhibitor TG100-115 provides neuroprotection against neonatal hypoxic-ischemic brain injury

TRPM7激酶抑制剂TG100-115对新生儿缺氧缺血性脑损伤具有神经保护作用

Acta Pharmacologica Sinica

IF8.4

2026-04-270

PRE

Inhibiting the transient receptor potential melastatin 2 channel in microglia: current evidence and therapeutic potential in neurological disorders

抑制小胶质细胞中的瞬时受体电位melastatin 2通道: 当前证据和神经系统疾病的治疗潜力

Acta Pharmacologica Sinica

IF8.4

2026-04-230

OAAI

From calcium signaling to cardiovascular pharmacology: TRPM7 as a key mechanistic regulator and emerging pharmacological focus

从钙信号到心血管药理学：TRPM7作为关键机制调节器和新兴的药理学焦点

Acta Pharmacologica Sinica

IF8.4

2026-04-080

PRE

Herbal bioactive compounds modulating ferroptosis and pyroptosis in neonatal hypoxic-ischemic brain injury: a systematic review of molecular basis, proposed crosstalk, and translational challenges

天然产物生物活性化合物在新生儿缺氧缺血性脑损伤中调节铁死亡和细胞焦亡：分子基础、假说交互作用及转化挑战的系统综述

Phytomedicine

IF8.3

2026-01-010

OAAI

Noncanonical role of astrocytic mitochondrial Cx43: suppressing IDH3α to sustain glycolytic homeostasis against depression

星形胶质细胞线粒体Cx43的非经典作用：抑制IDH3α以维持抗抑郁状态下的糖酵解稳态

Cell Death & Disease

IF9.6

2025-12-080

Therapeutic Potential of KATP Channels in the Attenuation of Parkinson’s Disease Pathogenesis and Progression – A Review

ATP敏感性钾通道在减轻帕金森病发病机制和进展中的治疗潜力——综述

Neurochemistry International

IF4

2025-11-210

OAAI

Microglial Activation and Inflammatory Responses in Parkinson's Disease Models Are Attenuated by TRPM2 Depletion

小胶质细胞活化及炎症反应在帕金森病模型中可被TRPM2耗竭所减弱

Glia

IF5.1

2025-07-150

OAAI

AD16 attenuates neuroinflammation induced by cerebral ischemia through down-regulating astrocytes A1 polarization

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-09-011

OAAI

TRPM7 in neurodevelopment and therapeutic prospects for neurodegenerative disease

CELL CALCIUM

IF4

2024-06-010

PRE

Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway (vol 13, pg 13, 2015)

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-04-290

Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral Sarcothelia edmondsoni

JOURNAL OF NATURAL PRODUCTS

IF3.6

2024-03-271

PRE

Rasal1 regulates calcium dependent neuronal maturation by modifying microtubule dynamics

CELL AND BIOSCIENCE

IF6.2

2024-01-210

OAAI

SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice

COMMUNICATIONS BIOLOGY

IF5.1

2024-01-051

OAAI

A small molecule 20C from Gastrodia elata inhibits a-synuclein aggregation and prevents progression of Parkinson's disease

CELL DEATH & DISEASE

IF9.6

2023-09-068

OAAI

A novel small-molecular CCR5 antagonist promotes neural repair after stroke

一种新型小分子CCR5拮抗剂促进卒中后神经修复

ACTA PHARMACOLOGICA SINICA

IF8.4

2023-05-1711

A breakdown of metabolic reprogramming in microglia induced by CKLF1 exacerbates immune tolerance in ischemic stroke

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-04-2516

OAAI

Hong-Shuo Sun

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