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D

Declan King

University of Edinburgh
H指数:19
被引数:1,453

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Astrocyte Proximity Protects Synapses From Human Amyloid-Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease

星形胶质细胞邻近性保护突触免受人源β-淀粉样蛋白诱导的退化，该保护作用在早期阿尔茨海默病小鼠离体模型中得到证实

European Journal of Neuroscience
IF2.4
2026-04-010
OAAI
Gobbo, Francesco; King, Declan; Tulloch, Jane; Gobbo, Davide; Bonthron, Calum; Meftah, Soraya; Stoddart-Campbelton, Caleb; Tamura, Arisa; Rose, Jamie; Smith, Colin; Durrant, Claire; Spires-Jones, Tara L.
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy

证据表明，在人类进行性核上性麻痹中存在寡聚型tau蛋白的跨突触传播。

Nature Neuroscience
IF20
2025-07-160
OA
Robert I. McGeachan; Lois Keavey; Elizabeth M. Simzer; Ya Yin Chang; Jamie L. Rose; Maxwell P. Spires-Jones; Mollie Gilmore; Kristjan Holt; Soraya Meftah; Natalia Ravingerova; Cristina Scutariu; Lewis W. Taylor; Declan King; Makis Tzioras; Jane Tulloch; Sam A. Booker; Imran Liaquat; Nicole Hindley-Pollock; Bethany Geary; Colin Smith; Paul M. Brennan; Claire S. Durrant; Tara L. Spires-Jones
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures

生理性和病理性淀粉样β蛋白在活体人脑片培养中对突触的差异性作用

NATURE COMMUNICATIONS
IF15.7
2025-04-300
OA
McGeachan, Robert I.; Meftah, Soraya; Taylor, Lewis W.; Catterson, James H.; Negro, Danilo; Bonthron, Calum; Holt, Kristjan; Tulloch, Jane; Rose, Jamie L.; Gobbo, Francesco; Chang, Ya Yin; Elliott, Jamie; McLay, Lauren; King, Declan; Liaquat, Imran; Spires-Jones, Tara L.; Booker, Sam A.; Brennan, Paul M.; Durrant, Claire S.
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease
ACTA NEUROPATHOLOGICA
IF9.3
2024-02-066
OAAI
Colom-Cadena, Marti; Toombs, Jamie; Simzer, Elizabeth; Holt, Kristjan; McGeachan, Robert; Tulloch, Jane; Jackson, Rosemary J.; Catterson, James H.; Spires-Jones, Maxwell P.; Rose, Jamie; Waybright, Lora; Caggiano, Anthony O.; King, Declan; Gobbo, Francesco; Davies, Caitlin; Hooley, Monique; Dunnett, Sophie; Tempelaar, Robert; Meftah, Soraya; Tzioras, Makis; Hamby, Mary E.; Izzo, Nicholas J.; Catalano, Susan M.; Durrant, Claire S.; Smith, Colin; Dando, Owen; Spires-Jones, Tara L.
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8
CELL REPORTS MEDICINE
IF10.6
2023-09-0121
OAAI
Tzioras, Makis; Daniels, Michael J. D.; Davies, Caitlin; Baxter, Paul; King, Declan; Mckay, Sean; Varga, Balazs; Popovic, Karla; Hernandez, Madison; Stevenson, Anna J.; Barrington, Jack; Drinkwater, Elizabeth; Borella, Julia; Holloway, Rebecca K.; Tulloch, Jane; Moss, Jonathan; Latta, Clare; Kandasamy, Jothy; Sokol, Drahoslav; Smith, Colin; Miron, Veronique E.; Karadottir, Ragnhildur Thora; Hardingham, Giles E.; Henstridge, Christopher M.; Brennan, Paul M.; McColl, Barry W.; Spires-Jones, Tara L.
Synaptic resilience is associated with maintained cognition during ageing

突触弹性与衰老过程中维持的认知有关

ALZHEIMERS & DEMENTIA
IF11.1
2022-12-229
OA
King, Declan; Holt, Kris; Toombs, Jamie; He, Xin; Dando, Owen; Okely, Judith A.; Tzioras, Makis; Rose, Jamie; Gunn, Ciaran; Correia, Adele; Montero, Carmen; McAlister, Hannah; Tulloch, Jane; Lamont, Douglas; Taylor, Adele M.; Harris, Sarah E.; Redmond, Paul; Cox, Simon R.; Henstridge, Christopher M.; Deary, Ian J.; Smith, Colin; Spires-Jones, Tara L.
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease

在阿尔茨海默氏病模型中，淀粉样蛋白 β 和Tau协同作用引起可逆的行为和转录缺陷

CELL REPORTS
IF6.9
2019-12-01111
OAAI
Pickett, Eleanor K.; Herrmann, Abigail G.; McQueen, Jamie; Abt, Kimberly; Dando, Owen; Tulloch, Jane; Jain, Pooja; Dunnett, Sophie; Sohrabi, Sadaf; Fjeldstad, Maria P.; Calkin, Will; Murison, Leo; Jackson, Rosemary J.; Tzioras, Makis; Stevenson, Anna; d'Orange, Marie; Hooley, Monique; Davies, Caitlin; Colom-Cadena, Marti; Anton-Fernandez, Alejandro; King, Declan; Oren, Iris; Rose, Jamie; McKenzie, Chris-Anne; Allison, Elizabeth; Smith, Colin; Hardt, Oliver; Henstridge, Christopher M.; Hardingham, Giles E.; Spires-Jones, Tara L.

研究方向

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T
Tara L. Spires‐Jones
H 指数:79论文数:324被引数:2.4万
J
Jane Tulloch
H 指数:15论文数:47被引数:1,545
C
Colin Smith
H 指数:78论文数:424被引数:3.0万
J
Jamie Rose
H 指数:18论文数:55被引数:2,601
R
Rona Barron
H 指数:17论文数:88被引数:1,270
M
Makis Tzioras
H 指数:16论文数:46被引数:1,825
R
Robert I. McGeachan
H 指数:10论文数:35被引数:958
O
Owen Dando
H 指数:26论文数:94被引数:2,737
K
Kristján Holt
H 指数:7论文数:19被引数:351
C
Christopher M. Henstridge
H 指数:32论文数:82被引数:4,212