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A multivariable disease-specific model enhances prognostication beyond current Merkel cell carcinoma staging: An international cohort study of 10,958 patients Andrew, Tom W.; Erdmann, Sophie; Alrawi, Mogdad; Plummer, Ruth; Shalhout, Sophia Z.; Sondak, Vern; Brownell, Isaac; Lovat, Penny E.; Rose, Aidan 分享 收藏
Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule Kelly, George; Kataura, Tetsushi; Panek, Johan; Ma, Gailing; Salmonowicz, Hanna; Davis, Ashley; Kendall, Hannah; Brookes, Charlotte; Ayine-Tora, Daniel Moscoh; Banks, Peter; Nelson, Glyn; Dobby, Laura; Pitrez, Patricia R.; Booth, Laura; Costello, Lydia; Richardson, Gavin D.; Lovat, Penny; Przyborski, Stefan; Ferreira, Lino; Greaves, Laura; Szczepanowska, Karolina; von Zglinicki, Thomas; Miwa, Satomi; Brown, Max; Flagler, Michael; Oblong, John E.; Bascom, Charles C.; Carroll, Bernadette; Reynisson, Johannes; Korolchuk, Viktor I. 分享 收藏
Expression of AMBRA1 and loricrin in the epidermis overlying benign cutaneous naevi, including blue and dysplastic naevi, is similar to that seen in normal skin, but expression may rarely be altered in melanoma in situ Husain, Akhtar; Lovat, Penny; Richardson, Grant; Ness, Thomas; Jones, Claire; Graham, Catherine; Labus, Marie; Sloan, Philip 分享 收藏
AMBRA1 levels predict resistance to MAPK inhibitors in melanoma AMBRA1水平预测黑色素瘤对MAPK抑制剂的耐药性 Di Leo, Luca; Pagliuca, Chiara; Kishk, Ali; Rizza, Salvatore; Tsiavou, Christina; Pecorari, Chiara; Dahl, Christina; Pacheco, Maria Pires; Tholstrup, Rikke; Brewer, Jonathan Richard; Berico, Pietro; Hernando, Eva; Cecconi, Francesco; Ballotti, Robert; Bertolotto, Corine; Filomeni, Giuseppe; Gjerstorff, Morten Frier; Sauter, Thomas; Lovat, Penny; Guldberg, Per; De Zio, Daniela 分享 收藏
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Validation of epidermal AMBRA1 and loricrin (AMBLor) as a prognostic biomarker for nonulcerated American Joint Committee on Cancer stage I/II cutaneous melanoma Ewen, Tom; Husain, Akhtar; Stefanos, Niki; Barrett, Paul; Jones, Claire; Ness, Tom; Long, Anna; Horswell, Stuart; Bosomworth, Helen; Lowenstein, Joe; Richardson, Grant; Swan, David; Mcconnell, Ashleigh; Rose, Aidan; Andrew, Tom; Reynolds, Nick; Malvehy, Josep; Carrera, Christina; Alos, Llucia; Mailer, Sonia; Helm, Thomas; Ding, Liang; Bogner, Paul; Podlipnik, Sebastian; Puig, Susana; Mcarthur, Grant A.; Paragh, Gyorgy; Labus, Marie; Sloan, Philip; Armstrong, Jane L.; Lovat, Penny E. 分享 收藏
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Programmed cell death-1 receptor-mediated regulation of Tbet+NK1.1-innate lymphoid cells within the tumor microenvironment Lim, Jing Xuan; Lai, Chester Y.; Mallett, Grace E.; McDonald, David; Hulme, Gillian; Laba, Stephanie; Shapanis, Andrew; Payne, Megan; Patterson, Warren; Alexander, Michael; Coxhead, Jonathan; Filby, Andrew; Plummer, Ruth; Lovat, Penny E.; Sciume, Giuseppe; Healy, Eugene; Amarnath, Shoba 分享 收藏
Optimal surveillance strategies for patients with stage 1 cutaneous melanoma post primary tumour excision: three systematic reviews and an economic model Vale, Luke; Kunonga, Patience; Coughlan, Diarmuid; Kontogiannis, Vasileios; Astin, Margaret; Beyer, Fiona; Richmond, Catherine; Wilson, Dor; Bajwa, Dalvir; Javanbakht, Mehdi; Bryant, Andrew; Akor, Wanwuri; Craig, Dawn; Lovat, Penny; Labus, Marie; Nasr, Batoul; Cunliffe, Timothy; Hinde, Helena; Shawgi, Mohamed; Saleh, Daniel; Royle, Pam; Steward, Paul; Lucas, Rachel; Ellis, Robert 分享 收藏
Exendin-4 stimulates autophagy in pancreatic beta-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis Zummo, Francesco P.; Krishnanda, Stanislaus, I; Georgiou, Merilin; O'Harte, Finbarr P. M.; Parthsarathy, Vadivel; Cullen, Kirsty S.; Honkanen-Scott, Minna; Shaw, James A. M.; Lovat, Penny E.; Arden, Catherine 分享 收藏
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HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1 Antonioli, Manuela; Pagni, Benedetta; Vescovo, Tiziana; Ellis, Rob; Cosway, Benjamin; Rollo, Francesca; Bordoni, Veronica; Agrati, Chiara; Labus, Marie; Covello, Renato; Benevolo, Maria; Ippolito, Giuseppe; Robinson, Max; Piacentini, Mauro; Lovat, Penny; Fimia, Gian Maria 分享 收藏
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Measuring two proteins to help assess which melanomas are most likely to spread Ellis, R.; Tang, D.; Nasr, B.; Greenwood, A.; McConnell, A.; Anagnostou, M. E.; Elias, M.; Verykiou, S.; Bajwa, D.; Ewen, T.; Reynolds, N. J.; Barrett, P.; Carling, E.; Watson, G.; Armstrong, J.; Allen, A. J.; Horswell, S.; Labus, M.; Lovat, P. E. 分享 收藏
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Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas Ellis, R.; Tang, D.; Nasr, B.; Greenwood, A.; McConnell, A.; Anagnostou, M. E.; Elias, M.; Verykiou, S.; Bajwa, D.; Ewen, T.; Reynolds, N. J.; Barrett, P.; Carling, E.; Watson, G.; Armstrong, J.; Allen, A. J.; Horswell, S.; Labus, M.; Lovat, P. E. 分享 收藏
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