Michael D. Bartberger - Publications, H-index & Citations

Michael D. Bartberger

Duke University

45H指数

134论文数

8.3K被引数

收录论文 58

发表时间

ALTA3263: an oral, KRAS isoform-selective, dual ON/OFF state, non-covalent inhibitor induces regressions across KRAS G12V, G12D, and G12C cancer models

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Wang, T.; Ibanez, M.; Yu, K.; Fan, K.; Juan, J.; Perez, M.; Smith, T.; Walsh, B.; Kang, V.; Tyhonas, J.; Alvarez, N.; Tran, J.; Moorefield, K. S.; Phimister, A.; Zhu, X.; Chi, A.; Bartberger, M. D.; Murphy, E.

Discovery of ALTA-2618, the first allosteric, mutant-selective targeted therapy for AKT1 E17K driven cancers

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Murphy, Eric A.; Bartberger, Michael D.; Ibanez, Maureen; Smith, Troy T.; Alvarez, Nicole; Timple, Noel; Zhu, Xuefeng; Fan, Kevin; Yu, Kevin

Divergent Catalysis: Catalytic Asymmetric [4+2] Cycloaddition of Palladium Enolates 发散催化: 钯烯醇化物的催化不对称 [4 2] 环加成

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-05-15

OAAI

Flesch, Kaylin N.; Cusumano, Alexander Q.; Chen, Peng-Jui; Strong, Christian Santiago; Sardini, Stephen R.; Du, Yun E.; Bartberger, Michael D.; Goddard, William A., III; Stoltz, Brian M.

Development of UCT-01-097, a novel orally available ERK1/2 inhibitor for the treatment of ERK1/2 dependent cancers

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

O'Brien, Neil A.; McDermott, Martina S.; O'Boyle, Brendan M.; Reeves, Corey M.; Bartberger, Michael; Loson, Oliver; Chau, Kevin; Hong, Jenny J.; Jia, Weiping; Kamranpour, Naeimeh; Luo, Tong; Ayala, Raul; Madrid, Athena M.; Glaspy, John A.; Stoltz, Brian M.; Slamon, Dennis J.

The discovery and preclinical characterization of the potent covalent KRASG12C inhibitor UCT-001024

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Rose, Tristin E.; O'Boyle, Brendan M.; Hilf, Justin A.; Baker-Tripp, Emma L.; Feng, Zhengao; Yang, Kevin; Bartberger, Michael D.; Loson, Oliver C.; O'Brien, Neil A.; McDermott, Martina S.; Kamranpour, Naeimeh; Jia, Weiping; Luo, Tong; Ayala, Raul; Glasby, John; Stoltz, Brian M.; Slamon, Dennis J.

The discovery and preclinical characterization of the SAM-competitive PRMT5 inhibitor UCT-000445

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

McDermott, Martina S.; O'Brien, Neil A.; O'Boyle, Brendan; Bartberger, Michael; Loson, Oliver C.; Chau, Kevin; Schwab, Ella; Hong, Jenny; Zhou, Jiaying; Hu, Chuhong; Luo, Tong; Ayala, Raul; Glasby, John; Stoltz, Brian M.; Slamon, Dennis J.

Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malonates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-04-27

OAAI

Moghadam, Farbod A.; Hicks, Elliot F.; Sercel, Zachary P.; Cusumano, Alexander Q.; Bartberger, Michael D.; Stoltz, Brian M.

Iridium-catalyzed asymmetric trans-selective hydrogenation of 1,3-disubstituted isoquinolines

CHEMICAL SCIENCE

IF7.4

2022-01-01

OAAI

Kim, Alexia N.; Ngamnithiporn, Aurapat; Bartberger, Michael D.; Stoltz, Brian M.

Systematic Study of the Glutathione Reactivity of N-Phenylacrylamides: 2. Effects of Acrylamide Substitution N-苯丙酰胺的谷胱甘肽反应性的系统研究: 2.丙烯酰胺替代的影响

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-09-23

PREAI

Birkholz, Adam; Kopecky, David J.; Volak, Laurie P.; Bartberger, Michael D.; Chen, Yuping; Tegley, Christopher M.; Arvedson, Tara; McCarter, John D.; Fotsch, Christopher; Cee, Victor J.

Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines

ACS CATALYSIS

IF13.1

2020-02-10

OAAI

Kim, Alexia N.; Ngamnithiporn, Aurapat; Welin, Eric R.; Daiger, Martin T.; Grunanger, Christian U.; Bartberger, Michael D.; Virgil, Scott C.; Stoltz, Brian M.

Enantioselective total synthesis of (-)-myrifabral A and B

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Fulton, Tyler J.; Chen, Anthony Y.; Bartberger, Michael D.; Stoltz, Brian M.

Enantioselective synthesis of highly oxygenated acyclic quaternary center-containing building blocksviapalladium-catalyzed decarboxylative allylic alkylation of cyclic siloxyketones

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Ngamnithiporn, Aurapat; Iwayama, Toshihiko; Bartberger, Michael D.; Stoltz, Brian M.

Mechanistic Insights into the Racemization of Fused Cyclopropyl Isoxazolines

ORGANIC LETTERS

IF5

2019-12-20

PREAI

Quasdorf, Kyle W.; Birkholz, Adam B.; Bartberger, Michael D.; Colyer, John; Osgood, Stephen; Crossley, Kevin; Caille, Seb

Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-12-10

511

OAAI

Lanman, Brian A.; Allen, Jennifer R.; Allen, John G.; Amegadzie, Albert K.; Ashton, Kate S.; Booker, Shon K.; Chen, Jian Jeffrey; Chen, Ning; Frohn, Michael J.; Goodman, Guy; Kopecky, David J.; Liu, Longbin; Lopez, Patricia; Low, Jonathan D.; Ma, Vu; Minatti, Ana E.; Nguyen, Thomas T.; Nishimura, Nobuko; Pickrell, Alexander J.; Reed, Anthony B.; Shin, Youngsook; Siegmund, Aaron C.; Tamayo, Nuria A.; Tegley, Christopher M.; Walton, Mary C.; Wang, Hui-Ling; Wurz, Ryan P.; Xue, May; Yang, Kevin C.; Achanta, Pragathi; Bartberger, Michael D.; Canon, Jude; Hollis, L. Steven; McCarter, John D.; Mohr, Christopher; Rex, Karen; Saiki, Anne Y.; San Miguel, Tisha; Volak, Laurie P.; Wang, Kevin H.; Whittington, Douglas A.; Zech, Stephan G.; Lipford, J. Russell; Cee, Victor J.

Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-10-07

PREAI

Pettus, Liping H.; Bourbeau, Matthew P.; Bradley, Jodi; Bartberger, Michael D.; Chen, Kui; Hickman, Dean; Johnson, Michael; Liu, Qingyian; Manning, James R.; Nanez, Adrian; Siegmund, Aaron C.; Wen, Paul H.; Whittington, Douglas A.; Allen, Jennifer R.; Wood, Stephen

Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2019-08-20

OAAI

Shin, Youngsook; Jeong, Joon Won; Wurz, Ryan P.; Achanta, Pragathi; Arvedson, Tara; Bartberger, Michael D.; Campuzano, Iain D. G.; Fucini, Ray; Hansen, Stig K.; Ingersoll, John; Iwig, Jeffrey S.; Lipford, J. Russell; Ma, Vu; Kopecky, David J.; McCarter, John; San Miguel, Tisha; Mohr, Christopher; Sabet, Sudi; Saiki, Anne Y.; Sawayama, Andrew; Sethofer, Steven; Tegley, Christopher M.; Volak, Laurie P.; Yang, Kevin; Lanman, Brian A.; Erlanson, Daniel A.; Cee, Victor J.

Discovery of TRPM8 Antagonist (S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-08-27

PREAI

Horne, Daniel B.; Biswas, Kaustav; Brown, James; Bartberger, Michael D.; Clarine, Jeffrey; Davis, Carl D.; Gore, Vijay K.; Harried, Scott; Horner, Michelle; Kaller, Matthew R.; Lehto, Sonya G.; Liu, Qingyian; Ma, Vu V.; Monenschein, Holger; Nguyen, Thomas T.; Yuan, Chester C.; Youngblood, Beth D.; Zhang, Maosheng; Zhong, Wenge; Allen, Jennifer R.; Chen, Jian Jeffrey; Gavva, Narender R.

Enantioselective Pd-Catalyzed Decarboxylative Allylic Alkylation of Thiopyranones. Access to Acyclic, Stereogenic α-Quaternary Ketones

ORGANIC LETTERS

IF5

2017-09-13

OAAI

Alexy, Eric J.; Virgil, Scott C.; Bartberger, Michael D.; Stoltz, Brian M.

Fragment-Linking Approach Using 19F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β-Secretase (vol 59, pg 3732, 2016)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-03-28

OAAI

Jordan, John B.; Whittington, Douglas A.; Bartberger, Michael D.; Sickmier, E. Allen; Chen, Kui; White, Ryan D.; Cheng, Yuan; Judd, Ted