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C

Christian Mueller

genomic medicine unit

46H指数
157论文数
5.9K被引数
收录论文 83
发表时间
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Increasing peak capacity in preparative liquid chromatography for pharmaceutical drug discovery using elevated temperature and column downsizing采用高温和柱子小型化技术在药物发现中提高制备液相色谱的峰容量
errJournal of Chromatography A
IF4
err2026-09-26
err0
PREAI
errChristian H. Mueller; Christian Maiss
err分享
err收藏
Taming immune responses to AAV gene therapy by programmed in vivo Treg expansion通过程序化体内Treg扩增来调控AAV基因疗法的免疫反应
errMolecular Therapy
IF12
err2026-02-13
err0
errOAAI
errLavesh Gwalani; Mincheol Park; Alexandra B. Ysasi; Mona Motwani; Robert Jackson; Jie Bu; Zhengyu Luo; John Bladon; Edith L. Pfister; Christian Mueller; Sourav R. Choudhury
err分享
err收藏
AAV gene therapy for GBA1 related diseasesAAV基因疗法用于GBA1相关疾病
errMolecular Therapy
IF12
err2025-12-09
err0
PREAI
errSwathi Ayloo; Jae Cheon Ryu; Shih-Ching Chou; Lydia Blatnik; Erik Wischhof; Jie Bu; Lilu Guo; Mahmud Hossain; Dhiman Ghosh; William McCarty; Ann Byrne; Lilly Chai; Jennifer Clarke; Can Kayatekin; Bailin Zhang; S.Pablo Sardi; Martin Goulet; Bradford Elmer; Christian Mueller; Shyam Ramachandran
err分享
err收藏
Artificial miRNA mediated reduction of SNCA for the treatment of α-synucleinopathies人工miRNA介导的SNCA降低用于α-突触核蛋白病的治疗
errMolecular Therapy
IF12
err2025-11-12
err0
PREAI
errBradford Elmer; Erik Wischhof; Tiffany Chan; Thanga Aishwarya Mahendran; Jeff Ardinger; Brenda Richards; Dongyu Liu; James Bladon; Ye He; Robert Jackson; Michael Fleming; Franck Rapaport; Shameer Khader; Martin Goulet; Christian Mueller; Shyam Ramachandran
err分享
err收藏
SNAC: A Single-Nuclei Atlas of Capsid Distribution in Nonhuman Primate EyeSNAC：一种非人灵长类眼睛中衣壳分布的单核体图谱
errHuman Gene Therapy
IF4
err2025-09-26
err0
PREAI
errRachna Manek; Eugenia Lyashenko; Andre H. Kurlovs; Yinyin Huang; Jeremy Huang; Margaret Hennessy; Jason Wu; Jasmine Bloom; Tess Torregrosa; Edith L. Pfister; Pavitra Ramachandran; Virginia Savova; Christian Mueller; Giorgio Gaglia; Sourav R. Choudhury
err分享
err收藏
Development of an AAV-delivered microRNA gene therapy for Myotonic Dystrophy Type 1开发一种AAV递送的microRNA基因疗法用于强直性肌营养不良症1型
errMolecular Therapy
IF12
err2025-09-02
err0
errOAAI
errGiulio S. Tomassy; Wei Fan; Shuwen Cao; Zhengyu Luo; Alessandro Magli; Tracy Zhang; Kristen Boyle; Robert Jackson; Brenda Richards; Dongyu Liu; Franck Rapaport; Shameer Khader; Edith L. Pfister; Catherine O’Riordan; Amy Frederick; Jennifer Sullivan; James Cao; Nageswara Rao Kollu; Basel T. Assaf; Martin Goulet; Christian Mueller
err分享
err收藏
AAV delivery of artificial miRNA targeting MAPT for the reduction of tau pathology in Alzheimer’s diseaseAAV介导的人工miRNA靶向MAPT，以减少阿尔茨海默病中的tau病理。
errMolecular Therapy
IF12
err2025-09-01
err0
PREAI
errJessica M. Hogestyn; Erik Wischhof; Yao Chen; Tiffany Chan; Brenda Richards; Thangaaishwarya Mahendran; Johanna Adams; Daniel Dubreuil; Jie Bu; Robert Jackson; Martin Goulet; Christian Mueller; Shyam Ramachandran; Bradford Elmer
err分享
err收藏
The 2024 Nobel Prize: Impact of the Discovery of miRNA on the Field of Gene Therapy2024年诺贝尔奖：miRNA的发现对基因治疗领域的影响
errgene therapy
IF4
err2025-01-03
err0
PREAI
errMueller, Christian; Gao, Guangping; Flotte, Terence R.
err分享
err收藏
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors
errHEPATOLOGY
IF15.8
err2024-07-02
err0
PREAI
errKent, Deniz; Ng, Soon Seng; Syanda, Adam M.; Khoshkenar, Payam; Ronzoni, Riccardo; Li, Chao Zheng; Zieger, Marina; Greer, Cindy; Hatch, Stephanie; Segal, Joe; Blackford, Samuel J., I; Im, Yu Ri; Chowdary, Vivek; Ismali, Taylor; Danovi, Davide; Lewis, Patrick A.; Irving, James A.; Sahdeo, Sunil; Lomas, David A.; Ebner, Daniel; Mueller, Christian; Rashid, S. Tamir
err分享
err收藏
AAV-ARSA mediated gene replacement for the treatment of metachromatic leukodystrophy
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2024-02-01
err0
PREAI
errRamachandran, Shyam; Ardinger, Jeffery; Ramos, MiAngela; Guo, Lilu; Hossain, Mahmud; Ayloo, Swathi; Adams, Johanna; McCarty, William; Nass, Shelley; Goulet, Martin; Mueller, Christian
err分享
err收藏
Evaluation of a novel AAV capsid with widespread CNS and peripheral biodistribution in non-human primates
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2024-02-01
err0
PREAI
errRamachandran, Shyam; Hogestyn, Jessica; Ayloo, Swathi; Ryu, Jae; Ardinger, Jeffery; Ramos, MiAngela; Blatnik, Lydia; Nass, Shelley; Goulet, Martin; Mueller, Christian; Gonzalez-Meneses, Antonio
err分享
err收藏
Comparison of edoxaban and enoxaparin in a rat model of AlCl3-induced thrombosis of the superior sagittal sinus
errNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
IF3.1
err2023-06-01
err2
errOAAI
errHachenberger, M.; Yeniguen, M.; Suenner, L.; Hinchliffe, D.; Mueller, C.; Wietelmann, A.; Gerriets, T.; Tschernatsch, M.; Juenemann, M.; Gerner, S. T.; Doeppner, T. R.; Huttner, H. B.; Braun, T.
err分享
err收藏
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro
errNATURE COMMUNICATIONS
IF15.7
err2022-10-21
err30
errOAAI
errMeijboom, Katharina E.; Abdallah, Abbas; Fordham, Nicholas P.; Nagase, Hiroko; Rodriguez, Tomas; Kraus, Carolyn; Gendron, Tania F.; Krishnan, Gopinath; Esanov, Rustam; Andrade, Nadja S.; Rybin, Matthew J.; Ramic, Melina; Stephens, Zachary D.; Edraki, Alireza; Blackwood, Meghan T.; Kahriman, Aydan; Henninger, Nils; Kocher, Jean-Pierre A.; Benatar, Michael; Brodsky, Michael H.; Petrucelli, Leonard; Gao, Fen-Biao; Sontheimer, Erik J.; Brown, Robert H.; Zeier, Zane; Mueller, Christian
err分享
err收藏
Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates
errNATURE COMMUNICATIONS
IF15.7
err2022-05-04
err13
errOAAI
errMilani, Michela; Canepari, Cesare; Liu, Tongyao; Biffi, Mauro; Russo, Fabio; Plati, Tiziana; Curto, Rosalia; Patarroyo-White, Susannah; Drager, Douglas; Visigalli, Ilaria; Brombin, Chiara; Albertini, Paola; Follenzi, Antonia; Ayuso, Eduard; Mueller, Christian; Annoni, Andrea; Naldini, Luigi; Cantore, Alessio
err分享
err收藏
Evaluation of cytosine base editing and adenine base editing as a potential treatment for alpha-1 antitrypsin deficiency
errMOLECULAR THERAPY
IF12
err2022-04-01
err22
errOAAI
errPacker, Michael S.; Chowdhary, Vivek; Lung, Genesis; Cheng, Lo-, I; Aratyn-Schaus, Yvonne; Leboeuf, Dominique; Smith, Sarah; Shah, Aalok; Chen, Delai; Zieger, Marina; Cafferty, Brian J.; Yan, Bo; Ciaramella, Giuseppe; Gregoire, Francine M.; Mueller, Christian
err分享
err收藏
Ferret models of alpha-1 antitrypsin deficiency develop lung and liver disease
errJCI INSIGHT
IF6.1
err2022-03-08
err15
errOAAI
errHe, Nan; Liu, Xiaoming; Vegter, Amber R.; Evans, T. Idil A.; Gray, Jaimie S.; Guo, Junfeng; Moll, Shashanna R.; Guo, Lydia J.; Luo, Meihui; Ma, Ningxia; Sun, Xingshen; Liang, Bo; Yan, Ziying; Feng, Zehua; Qi, Lisi; Joshi, Arnav S.; Shahin, Weam; Yi, Yaling; Gibson-Corley, Katherine N.; Hoffman, Eric A.; Wang, Kai; Mueller, Christian; Engelhardt, John F.; Rosen, Bradley H.
err分享
err收藏
AAV gene therapy for Tay-Sachs disease
errNATURE MEDICINE
IF50
err2022-02-10
err67
errOAAI
errFlotte, Terence R.; Cataltepe, Oguz; Puri, Ajit; Batista, Ana Rita; Moser, Richard; McKenna-Yasek, Diane; Douthwright, Catherine; Gernoux, Gwladys; Blackwood, Meghan; Mueller, Christian; Tai, Phillip W. L.; Jiang, Xuntian; Bateman, Scot; Spanakis, Spiro G.; Parzych, Julia; Keeler, Allison M.; Abayazeed, Aly; Rohatgi, Saurabh; Gibson, Laura; Finberg, Robert; Barton, Bruce A.; Vardar, Zeynep; Shazeeb, Mohammed Salman; Gounis, Matthew; Tifft, Cynthia J.; Eichler, Florian S.; Brown, Robert H., Jr.; Martin, Douglas R.; Gray-Edwards, Heather L.; Sena-Esteves, Miguel
err分享
err收藏
SepA Enhances Shigella Invasion of Epithelial Cells by Degrading Alpha-1 Antitrypsin and Producing a Neutrophil Chemoattractant
errMBIO
IF4.7
err2021-12-21
err12
errOAAI
errMeza-Segura, Mario; Birtley, James R.; Maldonado-Contreras, Ana; Mueller, Christian; Simin, Karl J.; Stern, Lawrence J.; McCormick, Beth A.
err分享
err收藏
Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-07-09
err27
errOAAI
errDeuse, Tobias; Tediashvili, Grigol; Hu, Xiaomeng; Gravina, Alessia; Tamenang, Annika; Wang, Dong; Connolly, Andrew; Mueller, Christian; Mallavia, Benat; Looney, Mark R.; Alawi, Malik; Lanier, Lewis L.; Schrepfer, Sonja
err分享
err收藏
Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease帕金森病模型轴突退变机制的遗传多样性
errNEUROBIOLOGY OF DISEASE
IF5.6
err2021-07-01
err20
errOAAI
errPeters, Owen M.; Weiss, Alexandra; Metterville, Jake; Song, Lina; Logan, Robert; Smith, Gaynor A.; Schwarzschild, Michael A.; Mueller, Christian; Brown, Robert H.; Freeman, Marc
err分享
err收藏

研究方向

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合作学者
合作期刊
D
Dennis W. Dickson
H 指数: 218 · 论文数: 2.3K
G
George M. Church
H 指数: 190 · 论文数: 1.3K
L
Lewis L. Lanier
H 指数: 165 · 论文数: 709
J
James M. Wilson
H 指数: 155 · 论文数: 1.4K
S
Stanley L. Hazen
H 指数: 151 · 论文数: 757
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