Tom Scheidt - Publications, H-index & Citations

Tom Scheidt

University of Cambridge

13H指数

29论文数

700被引数

收录论文 16

发表时间

Structural defects in amyloid-β fibrils drive secondary nucleation 淀粉样蛋白β纤维的结构缺陷驱动二次成核

Nature Communications

IF15.7

2026-02-18

OAAI

Jing Hu; Tom Scheidt; Dev Thacker; Emil Axell; Elin Stemme; Urszula Łapińska; Stefan Wennmalm; Georg Meisl; Samo Curk; Maria Andreasen; Michele Vendruscolo; Paolo Arosio; Anđela Šarić; Jeremy D. Schmit; Tuomas P. J. Knowles; Emma Sparr; Sara Linse; Thomas C. T. Michaels; Alexander J. Dear

Protein-Specific Crowding Accelerates Aging in Protein Condensates

BIOMACROMOLECULES

IF5.4

2024-12-08

PREAI

Brzezinski, Mateusz; Argudo, Pablo G.; Scheidt, Tom; Yu, Miao; Hosseini, Elnaz; Kaltbeitzel, Anke; Lemke, Edward A.; Michels, Jasper J.; Parekh, Sapun H.

A genetically encoded anomalous SAXS ruler to probe the dimensions of intrinsically disordered proteins

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-12-06

PREAI

Yu, Miao; Gruzinov, Andrey Yu.; Ruan, Hao; Scheidt, Tom; Chowdhury, Aritra; Giofre, Sabrina; Mohammed, Ahmed S. A.; Caria, Joana; Sauter, Paul F.; Svergun, Dmitri I.; Lemke, Edward A.

Stressing the role of a short linear motif in ataxin-2 condensation

MOLECULAR CELL

IF16.6

2023-06-01

OAAI

Scheidt, Tom; Ruan, Hao; Yu, Miao; Lemke, Edward A.

Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum 人血清中同种抗体-HLA相互作用的微流控抗体亲和力分析

BIOSENSORS & BIOELECTRONICS

IF10.5

2023-05-01

OAAI

Schneider, Matthias M.; Scheidt, Tom; Priddey, Ashley J.; Xu, Catherine K.; Hu, Mengsha; Meisl, Georg; Devenish, Sean R. A.; Dobson, Christopher M.; Kosmoliaptsis, Vasilis; Knowles, Tuomas P. J.

RNA-binding protein dysfunction in neurodegeneration

MOLECULAR MECHANISMS OF NEURODEGENERATION

IF0

2021-12-22

PREAI

Popper, Bastian; Scheidt, Tom; Schieweck, Rico

Role of Solvent Compatibility in the Phase Behavior of Binary Solutions of Weakly Associating Multivalent Polymers

BIOMACROMOLECULES

IF5.4

2021-12-04

OAAI

Michels, Jasper J.; Brzezinski, Mateusz; Scheidt, Tom; Lemke, Edward A.; Parekh, Sapun H.

The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-09-21

PREAI

Scheidt, Tom; Carozza, Jacqueline A.; Kolbe, Carl C.; Aprile, Francesco A.; Tkachenko, Olga; Bellaiche, Mathias M. J.; Meisl, Georg; Peter, Quentin A. E.; Herling, Therese W.; Ness, Samuel; Castellana-Cruz, Marta; Benesch, Justin L. P.; Vendruscolo, Michele; Dobson, Christopher M.; Arosio, Paolo; Knowles, Tuomas P. J.

Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection

ANALYTICAL CHEMISTRY

IF6.7

2021-01-28

OAAI

Kartanas, Tadas; Levin, Aviad; Toprakcioglu, Zenon; Scheidt, Tom; Hakala, Tuuli A.; Charmet, Jerome; Knowles, Tuomas P. J.

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2020-09-28

132

PREAI

Linse, Sara; Scheidt, Tom; Bernfur, Katja; Vendruscolo, Michele; Dobson, Christopher M.; Cohen, Samuel I. A.; Sileikis, Eimantas; Lundqvist, Martin; Qian, Fang; O'Malley, Tiernan; Bussiere, Thierry; Weinreb, Paul H.; Xu, Catherine K.; Meisl, Georg; Devenish, Sean R. A.; Knowles, Tuomas P. J.; Hansson, Oskar

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-03

OAAI

Aprile, Francesco A.; Sormanni, Pietro; Podpolny, Marina; Chhangur, Shianne; Needham, Lisa-Maria; Ruggeri, Francesco S.; Perni, Michele; Limbocker, Ryan; Heller, Gabriella T.; Sneideris, Tomas; Scheidt, Tom; Mannini, Benedetta; Habchi, Johnny; Lee, Steven F.; Salinas, Patricia C.; Knowles, Tuomas P. J.; Dobson, Christopher M.; Vendruscolo, Michele

Multidimensional protein characterisation using microfluidic post-column analysis

LAB ON A CHIP

IF5.4

2020-01-01

OAAI

Scheidt, Tom; Kartanas, Tadas; Peter, Quentin; Schneider, Matthias M.; Saar, Kadi L.; Mueller, Thomas; Challa, Pavan Kumar; Levin, Aviad; Devenish, Sean; Knowles, Tuomas P. J.

Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Pansieri, Jonathan; Iashchishyn, Igor A.; Fakhouri, Hussein; Ostoji, Lucija; Malisauskas, Mantas; Musteikyte, Greta; Smirnovas, Vytautas; Schneider, Matthias M.; Scheidt, Tom; Xu, Catherine K.; Meisl, Georg; Knowles, Tuomas P. J.; Gazit, Ehud; Antoine, Rodolphe; Morozova-Roche, Ludmilla A.

Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-β aggregates

SCIENCE ADVANCES

IF12.5

2019-04-05

113

OAAI

Scheidt, Tom; Lapinska, Urszula; Kumita, Janet R.; Whiten, Daniel R.; Klenerman, David; Wilson, Mark R.; Cohen, Samuel I. A.; Linse, Sara; Vendruscolo, Michele; Dobson, Christopher M.; Knowles, Tuomas P. J.; Arosio, Paolo

Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens

VIRUSES-BASEL

IF3.5

2018-08-15

OAAI

Kunstmann, Sonja; Scheidt, Tom; Buchwald, Saskia; Helm, Alexandra; Mulard, Laurence A.; Fruth, Angelika; Barbirz, Stefanie

Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein-Polysaccharide Interactions

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-04-25

OAAI

Kang, Yu; Gohlke, Ulrich; Engstrom, Olof; Hamark, Christoffer; Scheidt, Tom; Kunstrnann, Sonja; Heinemann, Udo; Widmalm, Goran; Santer, Mark; Barbirz, Stefanie

研究方向