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K

Kenji Arakawa

hiroshima university
H指数:30
被引数:2,739
浏览量:0

个人简介

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教育背景

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工作经历

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荣誉奖项

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Discovery of actinomycin derivatives with improved selectivity against malaria parasites from a Streptomyces culture library

从链霉菌培养物文库中发现对疟原虫具有更高选择性的放线菌素衍生物

Journal of Antibiotics
IF2.7
2026-07-011
OA
Teshima, Aiko; Teklemichael, Awet Alem; Hirata, Asahi; Akimoto, Momoko; Taniguchi, Mayumi; Muslimin, Rukman; Ogaki, Sho; Ali, Alimuddin; Suzuki, Toshihiro; Mizukami, Shusaku; Arakawa, Kenji
A unique compound ameliorating endoplasmic reticulum stress and insulin resistance by binding to β tubulin

通过与 β 微管蛋白结合改善内质网应激和胰岛素抵抗的独特化合物

FASEB JOURNAL
IF4.2
2024-11-121
OA
Horiuchi, Keigo; Matsushima, Goshi; Wada, Momoe; Thon, Mina; Sobhy, Mohamed Hossam; Ayoub, Ahmed Taha; Hara, Misato; Yoshii, Michiko; Arakawa, Kenji; Ozawa, Koichiro; Hosoi, Toru
Discovery of antimalarial drugs from secondary metabolites in actinomycetes culture library
TROPICAL MEDICINE AND HEALTH
IF3.5
2024-07-091
OAAI
Teklemichael, Awet Alem; Teshima, Aiko; Hirata, Asahi; Akimoto, Momoko; Taniguchi, Mayumi; Khodakaramian, Gholam; Fujimura, Takashi; Tokumasu, Fuyuki; Arakawa, Kenji; Mizukami, Shusaku
Isolation of Hydrazide-alkenes with Different Amino Acid Origins from an Azoxy-alkene-Producing Mutant of Streptomyces rochei 7434AN4
JOURNAL OF NATURAL PRODUCTS
IF3.6
2023-08-250
PRE
Tanaka, Yu; Nagano, Haruka; Okano, Mei; Kishimoto, Takuya; Tatsukawa, Ayaka; Kunitake, Hirofumi; Fukumoto, Atsushi; Anzai, Yojiro; Arakawa, Kenji
Bioinspired computational design of lankacidin derivatives for improvement in antitumor activity
FUTURE MEDICINAL CHEMISTRY
IF3.4
2022-09-082
PRE
Ayoub, Ahmed Taha; Nishiura, Natsumi; Teshima, Aiko; Elrefaiy, Mohamed Ali; Muslimin, Rukman; Kiep Minh Do; Kodama, Takeshi; Lewis, Cody Wayne; Chan, Gordon; Morita, Hiroyuki; Arakawa, Kenji
Isolation, Biosynthetic Investigation, and Biological Evaluation of Maniwamycin G, an Azoxyalkene Compound from Streptomyces sp. TOHO-M025
JOURNAL OF NATURAL PRODUCTS
IF3.6
2022-06-112
PRE
Tatsukawa, Ayaka; Tanaka, Yu; Nagano, Haruka; Fukumoto, Atsushi; Anzai, Yojiro; Arakawa, Kenji
Production of Agrocinopine A by Ipomoea batatas Agrocinopine Synthase in Transgenic Tobacco and Its Effect on the Rhizosphere Microbial Community
molecular plant
IF3.4
2022-01-014
OA
Tanaka, Aiko; Ryder, Maarten H.; Suzuki, Takamasa; Uesaka, Kazuma; Yamaguchi, Nobuo; Amimoto, Tomoko; Otani, Motoyasu; Nakayachi, Osamu; Arakawa, Kenji; Tanaka, Nobukazu; Takemoto, Daigo
Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2022-01-012
PRE
Muslimin, Rukman; Nishiura, Natsumi; Teshima, Aiko; Minh Do, Kiep; Kodama, Takeshi; Morita, Hiroyuki; Lewis, Cody Wayne; Chan, Gordon; Ayoub, Ahmed Taha; Arakawa, Kenji
Discovery of a Polyamino Acid Antibiotic Solely Comprising L-β-Lysine by Potential Producer Prioritization-Guided Genome Mining
ACS CHEMICAL BIOLOGY
IF3.8
2021-12-104
PREAI
Yamanaka, Kazuya; Fukumoto, Hibiki; Yoshimura, Naoki; Arakawa, Kenji; Kato, Yasuo; Hamano, Yoshimitsu; Oikawa, Tadao
SrrB, a Pseudo-Receptor Protein, Acts as a Negative Regulator for Lankacidin and Lankamycin Production inStreptomyces rochei
FRONTIERS IN MICROBIOLOGY
IF4.5
2020-06-0911
OAAI
Misaki, Yuya; Yamamoto, Shouji; Suzuki, Toshihiro; Iwakuni, Miyuki; Sasaki, Hiroaki; Takahashi, Yuzuru; Inada, Kuninobu; Kinashi, Haruyasu; Arakawa, Kenji
Influence of the size of polystyrene synthesized through soap-free emulsion polymerization on antimicrobial activity
MATERIALS TODAY COMMUNICATIONS
IF4.5
2019-09-016
PREAI
Yamamoto, Tetsuya; Arakawa, Kenji; Furuta, Ryo; Teshima, Aiko
The genome sequence of Streptomyces rochei 7434AN4, which carries a linear chromosome and three characteristic linear plasmids
SCIENTIFIC REPORTS
IF3.9
2019-07-2927
OAAI
Nindita, Yosi; Cao, Zhisheng; Fauzi, Amirudin Akhmad; Teshima, Aiko; Misaki, Yuya; Muslimin, Rukman; Yang, Yingjie; Shiwa, Yuh; Yoshikawa, Hirofumi; Tagami, Michihira; Lezhava, Alexander; Ishikawa, Jun; Kuroda, Makoto; Sekizuka, Tsuyoshi; Inada, Kuninobu; Kinashi, Haruyasu; Arakawa, Kenji
Computational Prediction of the Mode of Binding of Antitumor Lankacidin C to Tubulin
ACS OMEGA
IF4.3
2019-02-2817
OAAI
Ayoub, Ahmed Taha; Elrefaiy, Mohamed Ali; Arakawa, Kenji
Antimicrobial activities of low molecular weight polymers synthesized through soap-free emulsion polymerization

通过无皂乳液聚合合成的低分子量聚合物的抗菌活性

EUROPEAN POLYMER JOURNAL
IF6.3
2018-12-0119
PREAI
Yamamo, Tetsuya; Arakawa, Kenji; Takahashi, Yuya; Sumiyoshi, Miho
Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2016-10-1821
PREAI
Ayoub, Ahmed Taha; Abou El-Magd, Rabab M.; Xiao, Jack; Lewis, Cody Wayne; Tilli, Tatiana Martins; Arakawa, Kenji; Nindita, Yosi; Chan, Gordon; Sun, Luxin; Glover, Mark; Klobukowski, Mariusz; Tuszynski, Jack
BIOSYNTHESIS Diversity between PKS and FAS
NATURE CHEMICAL BIOLOGY
IF13.7
2012-06-181
PREAI
Arakawa, Kenji
An autopsy case of adult-onset hereditary spastic paraplegia type 2 with a novel mutation in exon 7 of the proteolipid protein 1 gene
ACTA NEUROPATHOLOGICA
IF9.3
2011-11-2011
PRE
Suzuki, Satoshi O.; Iwaki, Toru; Arakawa, Kenji; Furuya, Hirokazu; Fujii, Naoki; Iwaki, Akiko
Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2011-01-3162
OAAI
Belousoff, Matthew J.; Shapira, Tal; Bashan, Anat; Zimmerman, Ella; Rozenberg, Haim; Arakawa, Kenji; Kinashi, Haruyasu; Yonath, Ada
The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2010-01-1162
OAAI
Auerbach, Tamar; Mermershtain, Inbal; Davidovich, Chen; Bashan, Anat; Belousoff, Matthew; Wekselman, Itai; Zimmerman, Ella; Xiong, Liqun; Klepacki, Dorota; Arakawa, Kenji; Kinashi, Haruyasu; Mankin, Alexander S.; Yonath, Ada
Improvement of lung abnormality detection in computed radiography using multi-objective frequency processing: Evaluation by receiver operating characteristics (ROC) analysis
EUROPEAN JOURNAL OF RADIOLOGY
IF3.3
2008-03-017
PREAI
Tagashira, Hiroyuki; Arakawa, Kenji; Yoshimoto, Masahiro; Mochizuki, Teruhito; Murase, Kenya; Yoshida, Hiroyuki

研究方向

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