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Abraham M. Lenhoff

University of Delaware

63H指数
251论文数
1.4W被引数
收录论文 136
发表时间
Modernizing the platform process of antibody purification for enhanced impurity clearance抗体纯化平台流程的现代化改造以提高杂质清除效率
err2025-11-17
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errOAAI
errJacob LeBarre; Dipendra Bhandari; Eduardo Barbieri; Qingbo Shu; Xuanwen Li; Divya Chandra; Xuankuo Xu; Michael Phillips; Jerome Bill; Taufika Williams; Patrick Gilbert; Christopher Major; David Roush; Steven Cramer; Abraham Lenhoff; Cristiana Boi; Ruben Carbonell; Stefano Menegatti
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Coupling high-throughput and modeling approaches to streamline early-stage process development for biologics将高通量与建模方法相结合,以简化生物制剂的早期工艺开发
err2025-01-23
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PREAI
errJohn P. Welsh; Scott H. Altern; Jessica Y. Lyall; Sean Burgess; Michael A. Rauscher; Abraham M. Lenhoff; Steven M. Cramer; Chris Williams
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Application of mechanistic modelling in membrane and fiber chromatography for purification of biotherapeutics - A review
err2024-02-01
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errOAAI
errQu, Yiran; Baker, Irene; Black, Jamie; Fabri, Louis; Gras, Sally L.; Lenhoff, Abraham M.; Kentish, Sandra E.
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Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing影响产品关联的因素作为生物加工中宿主细胞蛋白质持久性的机制
err2024-01-19
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PREAI
errOh, Young Hoon; Becker, Matthew L.; Mendola, Kerri M.; Choe, Leila H.; Min, Lie; Lee, Kelvin H.; Yigzaw, Yinges; Seay, Alexander; Bill, Jerome; Li, Xuanwen; Roush, David J.; Cramer, Steven M.; Menegatti, Stefano; Lenhoff, Abraham M.
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Predictive mechanistic modeling of loading and elution in protein A chromatography
err2024-01-01
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PREAI
errBhoyar, Soumitra; Kumar, Vijesh; Foster, Max; Xu, Xuankuo; Traylor, Steven J.; Guo, Jing; Lenhoff, Abraham M.
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Combined Effects of Pressure and Ionic Strength on Protein-Protein Interactions: An Empirical Approach
err2023-12-20
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PREAI
errPaul, Brian; Furst, Eric M.; Lenhoff, Abraham M.; Wagner, Norman J.; Teixeira, Susana C. M.
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Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing单克隆抗体生物加工中CHO宿主细胞蛋白的鉴定和表征
err2023-10-25
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PREAI
errOh, Young Hoon; Mendola, Kerri M.; Choe, Leila H.; Min, Lie; Lavoie, Ashton R.; Sripada, Sobhana A.; Williams, Taufika Islam; Lee, Kelvin H.; Yigzaw, Yinges; Seay, Alexander; Bill, Jerome; Li, Xuanwen; Roush, David J.; Cramer, Steven M.; Menegatti, Stefano; Lenhoff, Abraham M.
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Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography抗体捕获和抛光色谱中富含宿主细胞蛋白的聚集体的行为
err2023-08-01
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PREAI
errHerman, Chase E.; Min, Lie; Choe, Leila H.; Maurer, Ronald W.; Xu, Xuankuo; Ghose, Sanchayita; Lee, Kelvin H.; Lenhoff, Abraham M.
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Engineering protein A ligands to mitigate antibody loss during high-pH washes in protein A chromatography
err2023-05-01
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PREAI
errBhoyar, Soumitra; Foster, Max; Oh, Young Hoon; Xu, Xuankuo; Traylor, Steven J.; Guo, Jing; Ghose, Sanchayita; Lenhoff, Abraham M.
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Closed-loop modeling of central and intrinsic cardiac nervous system circuits underlying cardiovascular control
err2023-03-07
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errOAAI
errGee, Michelle M.; Lenhoff, Abraham M.; Schwaber, James S.; Ogunnaike, Babatunde A.; Vadigepalli, Rajanikanth
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Cell Therapy Biomanufacturing: Integrating Biomaterial and Flow-Based Membrane Technologies for Production of Engineered T-Cells
err2023-01-25
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errBomb, Kartik; LeValley, Paige J. J.; Woodward, Ian R. R.; Cassel, Samantha E. E.; Sutherland, Bryan P. P.; Bhattacharjee, Arnab; Yun, Zaining; Steen, Jonathan; Kurdzo, Emily; McCoskey, Jacob; Burris, David; Levine, Kara; Carbrello, Christina; Lenhoff, Abraham M. M.; Fromen, Catherine A. A.; Kloxin, April M. M.
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Characterization and implications of host-cell protein aggregates in biopharmaceutical processing生物制药加工中宿主细胞蛋白聚集体的表征和意义
err2023-01-12
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errOAAI
errOh, Young Hoon; Becker, Matthew L.; Mendola, Kerri M.; Choe, Leila H.; Min, Lie; Lee, Kelvin H.; Yigzaw, Yinges; Seay, Alexander; Bill, Jerome; Li, Xuanwen; Roush, David J.; Cramer, Steven M.; Menegatti, Stefano; Lenhoff, Abraham M.
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Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via flow-through affinity chromatography using peptide-based adsorbents走向连续mAb纯化: 使用基于肽的吸附剂通过流通亲和色谱从CHO细胞培养收获物中清除宿主细胞蛋白
err2022-04-22
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PREAI
errSripada, Sobhana Alekhya; Chu, Wenning; Williams, Taufika Islam; Teten, Matthew A.; Mosley, Brian J.; Carbonell, Ruben G.; Lenhoff, Abraham M.; Cramer, Steven M.; Bill, Jerome; Yigzaw, Yinges; Roush, David J.; Menegatti, Stefano
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Design of PLGA-Based Drug Delivery Systems Using a Physically-Based Sustained Release Model使用基于物理的缓释模型设计基于PLGA的药物递送系统
err2022-02-01
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errKoshari, Stijn H. S.; Shi, Xutao; Jiang, Linda; Chang, Debby; Rajagopal, Karthikan; Lenhoff, Abraham M.; Wagner, Norman J.
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Behavior of weakly adsorbing protein impurities in flow-through ion-exchange chromatography
err2022-02-01
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PREAI
errHerman, Chase E.; Xu, Xuankuo; Traylor, Steven J.; Ghose, Sanchayita; Li, Zheng Jian; Lenhoff, Abraham M.
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Robust mechanistic modeling of protein ion-exchange chromatography
err2021-12-01
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PREAI
errKumar, Vijesh; Leweke, Samuel; Heymann, William; von Lieres, Eric; Schlegel, Fabrice; Westerberg, Karin; Lenhoff, Abraham M.
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