David J. Owen - Publications, H-index & Citations

David J. Owen

Cambridge Institute for Medical Research

53H指数

121论文数

1.2W被引数

收录论文 61

发表时间

Architecture of clathrin-independent AP3:ARF1-coated carriers 笼蛋白非依赖的AP3:ARF1包被载体的结构

Science Advances

IF12.5

2026-05-15

OAAI

Jonathan G.G. Kaufman; Grigory Tagiltsev; Danièle S. Stalder; Rebecca J. Taylor; Ioana Sava; Hui Guo; Katarzyna A. Ciazynska; Nathan R. Zaccai; Sally R. Gray; Yvonne Vallis; Stefan Höning; Bernard T. Kelly; David C. Gershlick; John A.G. Briggs; David J. Owen

AAK1-mediated phosphorylation of PDLIM5 and Talin1 promotes focal adhesion disassembly to accelerate cell migration AAK1介导的PDLIM5和Talin1磷酸化促进 focal adhesion 解聚以加速细胞迁移

Nature Communications

IF15.7

2026-05-04

OAAI

Daniela Krocianova; Alexander D. Dagg; Rory A. Clayton; David Potesil; Veronika Fedorova; Adam Harmanec; Viktoria Benova; Veronika Bosakova; Jonathan G. G. Kaufman; Petra Martinkova; Miroslava Alblova; Bernard T. Kelly; Katerina Hanakova; Pavel Roudnicky; Stephanie J. Spielman; Jan Fric; Filip Sroubek; Josef Houser; Antoni G. Wrobel; Evzen Boura; David J. Owen; Zbynek Zdrahal; Zuzana Kadlecova

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks 凝聚体与外被物——网格蛋白组装与蛋白质网络生长的相互调控

Nature Communications

IF15.7

2025-10-15

OAAI

Brandon T. Malady; Andromachi Papagiannoula; Advika Kamatar; Susovan Sarkar; Gavin T. Lebrun; Liping Wang; Carl C. Hayden; Eileen M. Lafer; David J. Owen; Sigrid Milles; Jeanne C. Stachowiak

The mechanistic basis of cargo selection during Golgi maturation 高尔基体成熟过程中货物选择的作用机制基础

Science Advances

IF12.5

2025-10-03

PREAI

Rebecca J. Taylor; Nikita Zubkov; Katarzyna A. Ciazynska; Jonathan G. G. Kaufman; Grigory Tagiltsev; David J. Owen; John A. G. Briggs; Sean Munro

Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis 结合AP2与生物膜模拟血浆膜相互作用的综合热力学和时间分辨结构分析，为网格蛋白介导的内吞作用提供了见解。

Communications Biology

IF5.1

2025-08-12

OAAI

Armando Maestro; Nathan R. Zaccai; Juan F. Gonzalez-Martinez; Pablo Sanchez-Puga; Javier Tajuelo; Miguel A. Rubio; Andreas Santamaria; Javier Carrascosa-Tejedor; Daniel Pereira; Ildefonso Marín-Montesinos; Philipp Gutfreund; Richard Campbell; Jurij Kotar; Bernard T. Kelly; Pietro Cicuta; David J. Owen

Structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes 与含磷脂酰肌醇4，5-双磷酸酯的模型膜结合后，内吞衔接蛋白的结构分子细节平静下来

Communications Chemistry

IF6.2

2025-07-29

OAAI

Andreas Santamaria; Daniel Pereira; Nisha Pawar; Bernard T. Kelly; Javier Carrascosa-Tejedor; Mariana Sardo; Luís Mafra; Giovanna Fragneto; David J. Owen; Ildefonso Marín-Montesinos; Eduardo Guzmán; Nathan R. Zaccai; Armando Maestro

Engineering curvature: block copolymer lithography for the fabrication of curved lipid membranes and their impact on protein-membrane interactions 工程曲率：嵌段共聚物光刻技术在弯曲脂质膜制备及其对蛋白-膜相互作用影响中的应用

JOURNAL OF MATERIALS CHEMISTRY B

IF5.7

2025-01-01

OAAI

Menendez, Lucia Suarez; Owen, David J.; Zaccai, Nathan R.; Maestro, Armando

Cargo selective vesicle tethering: The structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23

SCIENCE ADVANCES

IF12.5

2024-03-29

OAAI

Cattin-Ortola, Jerome; Kaufman, Jonathan G. G.; Gillingham, Alison K.; Wagstaff, Jane L.; Peak-Chew, Sew-Yeu; Stevens, Tim J.; Boulanger, Jerome; Owen, David J.; Munro, Sean

Repurposing an endogenous degradation domain for antibody-mediated disposal of cell-surface proteins

EMBO REPORTS

IF6.2

2024-01-29

OAAI

Schmitt, Janika; Poole, Emma; Groves, Ian; Owen, David J.; Graham, Stephen C.; Sinclair, John; Kelly, Bernard T.

Engineering phosphatidylinositol-4,5-bisphosphate model membranes enriched in endocytic cargo: A neutron reflectometry, AFM and QCM-D structural study

COLLOIDS AND SURFACES B-BIOINTERFACES

IF5.6

2023-07-01

OAAI

Pereiraa, Daniel; Santamaria, Andreas; Pawar, Nisha; Carrascosa-Tejedor, Javier; Sardo, Mariana; Mafra, Luis; Guzman, Eduardo; Owen, David J.; Zaccai, Nathan R.; Maestro, Armando; Marin-Montesinos, Ildefonso

HPV-16 E7 Interacts with the Endocytic Machinery via the AP2 Adaptor μ2 Subunit

MBIO

IF4.7

2022-12-20

OAAI

Basukala, Om; Trejo-Cerro, Oscar; Myers, Michael P.; Pim, David; Massimi, Paola; Thomas, Miranda; Guarnaccia, Corrado; Owen, David; Banks, Lawrence

FCHO controls AP2's initiating role in endocytosis through a Ptdlns(4,5)P2-dependent switch

SCIENCE ADVANCES

IF12.5

2022-04-29

OAAI

Zaccai, Nathan R.; Kadlecova, Zuzana; Dickson, Veronica Kane; Korobchevskaya, Kseniya; Kamenicky, Jan; Kovtun, Oleksiy; Umasankar, Perunthottathu K.; Wrobel, Antoni G.; Kaufman, Jonathan G. G.; Gray, Sally R.; Qu, Kun; Evans, Philip R.; Fritzsche, Marco; Sroubek, Filip; Hoening, Stefan; Briggs, John A. G.; Kelly, Bernard T.; Owen, David J.; Traub, Linton M.

A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers BLOC-1-AP-3超级复合物将顺式陷阱复合物分类为内体衍生的管状运输载体

JOURNAL OF CELL BIOLOGY

IF6.4

2021-04-22

OAAI

Bowman, Shanna L.; Le, Linh; Zhu, Yueyao; Harper, Dawn C.; Sitaram, Anand; Theos, Alexander C.; Sviderskaya, Elena, V; Bennett, Dorothy C.; Raposo-Benedetti, Graca; Owen, David J.; Dennis, Megan K.; Marks, Michael S.

Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly

SCIENCE ADVANCES

IF12.5

2021-03-26

OAAI

Leneva, Natalya; Kovtun, Oleksiy; Morado, Dustin R.; Briggs, John A. G.; Owen, David J.

Linton Mark Traub (1962-2020)

JOURNAL OF CELL BIOLOGY

IF6.4

2021-01-06

OAAI

Aridor, Meir; Owen, David J.

Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29

NATURE COMMUNICATIONS

IF15.7

2020-10-06

OAAI

Crawley-Snowdon, Harriet; Yang, Ji-Chun; Zaccai, Nathan R.; Davis, Luther J.; Wartosch, Lena; Herman, Emily K.; Bright, Nicholas A.; Swarbrick, James S.; Collins, Brett M.; Jackson, Lauren P.; Seaman, Matthew N. J.; Luzio, J. Paul; Dacks, Joel B.; Neuhaus, David; Owen, David J.

Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles

SCIENCE ADVANCES

IF12.5

2020-07-24

OAAI

Kovtun, Oleksiy; Dickson, Veronica Kane; Kelly, Bernard T.; Owen, David J.; Briggs, John A. G.

Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation (vol 50, pg 494, 2019)

DEVELOPMENTAL CELL

IF8.7

2020-03-01

OAAI

Wrobel, Antoni G.; Kadlecova, Zuzana; Kamenicky, Jan; Yang, Ji-Chun; Herrmann, Torsten; Kelly, Bernard T.; McCoy, Airlie J.; Evans, Philip R.; Martin, Stephen; Mueller, Stefan; Salomon, Susanne; Sroubek, Filip; Neuhaus, David; Honing, Stefan; Owen, David J.

SYT1-associated neurodevelopmental disorder: a case series

BRAIN

IF11.7

2018-08-13

101

OAAI

Baker, Kate; Gordon, Sarah L.; Melland, Holly; Bumbak, Fabian; Scott, Daniel J.; Jiang, Tess J.; Owen, David; Turner, Bradley J.; Boyd, Stewart G.; Rossi, Mari; Al-Raqad, Mohammed; Elpeleg, Orly; Peck, Dawn; Mancini, Grazia M. S.; Wilke, Martina; Zollino, Marcella; Marangi, Giuseppe; Weigand, Heike; Borggraefe, Ingo; Haack, Tobias; Stark, Zornitza; Sadedin, Simon; Tan, Tiong Yang; Jiang, Yunyun; Gibbs, Richard A.; Ellingwood, Sara; Amaral, Michelle; Kelley, Whitley; Kurian, Manju A.; Cousin, Michael A.; Raymond, F. Lucy

Contribution of the clathrin adaptor AP-1 subunit μ1 to acidic cluster protein sorting

JOURNAL OF CELL BIOLOGY

IF6.4

2017-07-25

OAAI

Negredo, Paloma Navarro; Edgar, James R.; Wrobel, Antoni G.; Zaccai, Nathan R.; Antrobus, Robin; Owen, David J.; Robinson, Margaret S.

研究方向