Mengji Lu - Publications, H-index & Citations

Mengji Lu

university of duisburg essen

60H指数

444论文数

1.5W被引数

收录论文 189

发表时间

Glycolysis Drives TLR Ligand-Induced Maturation and Immune Activation of Liver Sinusoidal Endothelial Cells 糖酵解驱动TLR配体诱导的肝窦内皮细胞成熟和免疫激活

Liver International

IF5.2

2026-09-05

PREAI

Yiwen Shu; Hu Yan; Hang Sun; Xin Gu; Elisabeth Littwitz-Salomon; Jia Liu; Jun Wu; Dongliang Yang; Xin Zheng; Mengji Lu; Yanqin Du

Zinc finger protein ZBTB7A suppresses hepatitis B virus replication by attenuating FXRα-mediated HBV transcription and lowering covalently closed circular DNA levels 锌指蛋白ZBTB7A通过减弱FXRα介导的HBV转录和降低共价闭合环状DNA水平抑制乙型肝炎病毒复制

Antiviral Research

IF4

2026-06-01

PREAI

Xu, Dan; Zhao, Zhenyu; Guo, Beinu; Wei, Zhen; Li, Chen; Luo, Sichen; Shu, Wen; Shen, Zhongliang; Lu, Mengji; Zhang, Jiming; Zou, Hecun; Li, Fahong; Lin, Yong

Mitochondrial respiratory chain regulates HBV clearance through dual modulation of lysosomal acidification 线粒体呼吸链通过双重调节溶酶体酸化来调控HBV清除

Emerging Microbes & Infections

IF7.5

2025-10-07

OAAI

Zhiqiang Wei; Yanying Yan; Lingzhu Zhao; Chen Li; Jinjin Qi; Dandan Chen; Xiuzhen Huang; Minwei Li; Zhengyun Xiao; Guohua Lou; Zhenggang Yang; Mengji Lu; Xueyu Wang; Min Zheng

RAB1A promotes hepatitis B virus replication by enhancing PPARα-mediated viral transcription and inducing ULK1-mediated autophagy RAB1A通过增强PPARα介导的病毒转录和诱导ULK1介导的自噬来促进乙型肝炎病毒复制

International Journal of Biological Macromolecules

IF8.5

2025-07-24

PREAI

Chen Li; Zhenyu Zhao; Beinu Guo; Dan Xu; Sihui Li; Haihuan Tang; Bei Jia; Fahong Li; Jiming Zhang; Hecun Zou; Mengji Lu; Ailong Huang; Yong Lin

Regulatory T cells suppress TLR9-induced formation of intrahepatic myeloid-cell aggregates for T cell population expansion in liver 调节性T细胞抑制TLR9诱导的肝内髓系细胞聚集物的形成，以促进肝脏T细胞群体的扩增。

MEDICAL MICROBIOLOGY AND IMMUNOLOGY

IF3

2025-05-14

PREAI

Yanqin Du; Mengxiao Zhao; Xiaoqing Zeng; Shichuan Wang; Qin Wang; Liwei Chen; Xuecheng Yang; Xuemei Feng; Mengji Lu; Ulf Dittmer; Kathrin Sutter; Xin Zheng; Dongliang Yang; Chunli Xu; Jia Liu

ESCRT Machinery in HBV Life Cycle: Dual Roles in Autophagy and Membrane Dynamics for Viral Pathogenesis HBV生命周期中的ESCRT Machinery：在自噬和膜动力学中对病毒致病性的双重作用

CELLS

IF5.2

2025-04-16

OAAI

Li, Jia; Prange, Reinhild; Lu, Mengji

Amphisome plays a role in HBV production and release through the endosomal and autophagic pathways

HEPATOLOGY COMMUNICATIONS

IF4.6

2025-04-01

OAAI

Li, Jia; Kemper, Thekla; Broering, Ruth; Lin, Yong; Wang, Xueyu; Lu, Mengji

Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion 比较急性期与艾滋病期ART启动对HIV-1整合位点和克隆扩增的影响

SIGNAL TRANSDUCTION AND TARGETED THERAPY

IF52.7

2025-01-10

OAAI

Wang, Jun; Xiao, Nan; Zhu, Zhengnong; Qiao, Haiyan; Zhao, Fang; Zhang, Lukun; Gou, Jizhou; Lu, Mengji; He, Yun; Lu, Hongzhou; Li, Qian

The host gene CSTF2 regulates HBV replication via HBV PRE-induced nuclear export 宿主基因CSTF2通过HBV PRE诱导的核输出调控HBV复制

ACTA BIOCHIMICA ET BIOPHYSICA SINICA

IF3.4

2024-12-24

OAAI

Wang, JY; Li, J; Xie, WT; Shen, ZL; Wu, JW; Mao, RC; Lu, MJ; Zhang, JM

Deciphering lung granulomas in HIV & TB co-infection: unveiling macrophages aggregation with IL6R/STAT3 activation

EMERGING MICROBES & INFECTIONS

IF7.5

2024-06-18

OAAI

Li, Qian; Wang, Cheng; Gou, Jizhou; Kitanovski, Simo; Tang, Xiangyi; Cai, Yixuan; Zhang, Chenxia; Zhang, Xiling; Zhang, Zhenfeng; Qiu, Yuanwang; Zhao, Fang; Lu, Mengji; He, Yun; Wang, Jun; Lu, Hongzhou

Interleukin-6 classic and trans-signaling utilize glucose metabolism reprogramming to achieve anti- or pro-inflammatory effects

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2024-06-01

PREAI

Xu, Shilei; Deng, Ke-Qiong; Lu, Chengbo; Fu, Xin; Zhu, Qingmei; Wan, Shiqi; Zhang, Lin; Huang, Yu; Nie, Longyu; Cai, Huanhuan; Wang, Qiming; Zeng, Hao; Zhang, Yufeng; Wang, Fubing; Chen, Yu; Ren, Hong; Yan, Huan; Xu, Ke; Zhou, Li; Lu, Mengji; Zhu, Ying; Liu, Shi; Lu, Zhibing

Hepatitis B surface antigen expression impairs endoplasmic reticulum stress-related autophagic flux by decreasing LAMP2

JHEP REPORTS

IF7.5

2024-04-01

OAAI

Liang, Yaojie; Luo, Xufeng; Schefczyk, Stefan; Muungani, Lorraine T.; Deng, Hui; Wang, Baoju; Baba, Hideo A.; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut H.; Broering, Ruth

Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis

SCIENTIFIC REPORTS

IF3.9

2023-12-20

OAAI

Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Hasenberg, Mike; Walkenfort, Bernd; Trippler, Martin; Schuhenn, Jonas; Sutter, Kathrin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut H.; Broering, Ruth

Targeted mutations in IFNα2 improve its antiviral activity against various viruses

MBIO

IF4.7

2023-12-19

OAAI

Karakoese, Zehra; Le-Trilling, Vu-Thuy Khanh; Schuhenn, Jonas; Francois, Sandra; Lu, Mengji; Liu, Jia; Trilling, Mirko; Hoffmann, Daniel; Dittmer, Ulf; Sutter, Kathrin

Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways

EMERGING MICROBES & INFECTIONS

IF7.5

2023-10-26

OAAI

Zhao, Zhenyu; Wei, Zhen; Zheng, Jiaxin; Li, Zhihong; Zou, Hecun; Wen, Xiang; Li, Fahong; Wang, Xueyu; Huang, Qian; Zeng, Huaqing; Fan, Hui; Cai, Xuefei; Zhang, Jiming; Jia, Bei; Huang, Ailong; Lu, Mengji; Lin, Yong

Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-10-25

OAAI

Westmeier, Jaana; Brochtrup, Annika; Paniskaki, Krystallenia; Karakoese, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Limmer, Andreas; Mittermueller, Daniela; Liu, Jia; Zheng, Xin; Koval, Tetiana; Kaidashev, Igor; Berger, Marc Moritz; Herbstreit, Frank; Brenner, Thorsten; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy

MAVS integrates glucose metabolism and RIG-I-like receptor signaling

NATURE COMMUNICATIONS

IF15.7

2023-09-02

OAAI

He, Qiao-qiao; Huang, Yu; Nie, Longyu; Ren, Sheng; Xu, Gang; Deng, Feiyan; Cheng, Zhikui; Zuo, Qi; Zhang, Lin; Cai, Huanhuan; Wang, Qiming; Wang, Fubing; Ren, Hong; Yan, Huan; Xu, Ke; Zhou, Li; Lu, Mengji; Lu, Zhibing; Zhu, Ying; Liu, Shi

Nuclear translocation of YAP drives BMI1-associated hepatocarcinogenesis in hepatitis B virus infection

LIVER INTERNATIONAL

IF5.2

2023-06-14

OAAI

Luo, Xufeng; Zhang, Rui; Schefczyk, Stefan; Liang, Yaojie; Lin, Shu S.; Liu, Shi; Baba, Hideo A.; Lange, Christian M.; Wedemeyer, Heiner; Lu, Mengji; Broering, Ruth

Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo

VIRUSES-BASEL

IF3.5

2023-05-19

OAAI

Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Trippler, Martin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut H.; Broering, Ruth

Mitochondrial HIGD1A inhibits hepatitis B virus transcription and replication through the cellular PNKD-NF-κB-NR2F1 nexus

JOURNAL OF MEDICAL VIROLOGY

IF4.6

2023-04-21

PREAI

Xie, Zhanglian; Shen, Sheng; Huang, Kuiyuan; Wang, Weibin; Liu, Ziying; Zhang, Haixing; Lu, Mengji; Sun, Jian; Hou, Jinlin; Liu, Hongyan; Guo, Haitao; Zhang, Xiaoyong

研究方向