Juan Iovanna - Publications, H-index & Citations

Juan Iovanna

cnrs

86H指数

709论文数

3.7W被引数

收录论文 239

发表时间

Machine learning integration of thermal liquid biopsy and clinical biomarkers for pancreatic cancer diagnosis and prognosis: A retrospective cohort study 机器学习整合热液体活检和临床生物标志物用于胰腺癌诊断和预后：一项回顾性队列研究

Intelligent Medicine

IF6.9

2026-07-08

OAAI

Sonia Hermoso-Durán; Astrid Zedlitz Johansen; Julia Sidenius Johansen; Claus Larsen Feltoft; Carsten Palnæs Hansen; Francisco Javier Falcó-Martí; Nicolas Fraunhoffer; Oscar Sanchez-Gracia; Pablo Fernández Garrido; Sonia Vega; Ángel Lanas; Juan Iovanna; Adrian Velazquez-Campoy; Olga Abian

Why isn’t an oncogenic mutation in KRAS enough to induce and sustain transformation?为什么KRAS的致癌突变不足以诱导和维持转化？

Critical Reviews in Oncology/Hematology

IF0

2026-01-06

PREAI

Juan Iovanna; Nelson Dusetti

Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer 在药物耐受性持续细胞中，氧化还原代谢的适应性是预防胰腺癌复发的薄弱环节。

Oncogenesis

IF6.4

2025-12-09

OAAI

Nadine Abdel Hadi; Gabriela Reyes-Castellanos; Tristan Gicquel; Scarlett Gallardo-Arriaga; Emma Cosialls; Emeline Boet; Jean-Emmanuel Sarry; Rawand Masoud; Juan Iovanna; Alice Carrier

Corrigendum to “Bimodal silencing of the acinar cell-specific mRNA translation repressor PAIP2B defines a poor prognostic subgroup within the classical pancreatic tumor type” [Cancer Lett. 632 (2025) 217971]勘误：针对“经典型胰腺肿瘤类型中，腺泡细胞特异性mRNA翻译抑制因子PAIP2B的双模沉默定义了一个预后不良的亚群”[Cancer Lett. 632 (2025) 217971]

Cancer Letters

IF10.1

2025-12-04

OAAI

Eulalie Corre; Amandine Alard; Catherine Marbœuf; Charline Lasfargues; Sandra Dailhau; Nicolas Gilbert; Yuna Blum; Rémy Nicolle; Juan Iovanna; Nelson Dusetti; Stéphane Pyronnet

Evaluating the therapeutic role of salvianolic acid A on pancreatic cancer cells through interaction with the intrinsically disordered protein NUPR1 通过与小分子无序蛋白NUPR1的相互作用，评估丹参酸A对胰腺癌细胞的治疗作用

International Journal of Biological Macromolecules

IF8.5

2025-12-03

PREAI

María Gabriela Álvarez-Rodríguez; Matías Estaras; Felipe Hornos; Bruno Rizzuti; Patricia Santofimia-Castaño; Juan L. Iovanna; José L. Neira

Synergistic antitumor activity of sorafenib and the NUPR1 inhibitor LZX-2-73 in multiple cancer models sorafenib与NUPR1抑制剂LZX-2-73在多种癌症模型中的协同抗肿瘤活性

Cell Death & Disease

IF9.6

2025-11-17

OAAI

Xi Liu; Matías Estaras; Emma Cosialls; Ling Peng; Patricia Santofimia-Castaño; Juan Iovanna

Toward Precision Chemotherapy for Pancreatic Cancer Guided by Transcriptomic Signatures 基于转录组学特征指导的胰腺癌精准化疗研究

United European Gastroenterology Journal

IF6.7

2025-10-08

OAAI

Brice Chanez; Matthieu Delaye; Nicolas Fraunhoffer; Juan Iovanna; Cindy Neuzillet; Nelson Dusetti

The Mitochondrial Catastrophe Induced by NUPR1 Inhibitors as a Novel Strategy to Fight Against Cancer NUPR1抑制剂诱导的线粒体灾难作为一种对抗癌症的新型策略

critical reviews in oncology hematology

IF0

2025-08-15

PREAI

Juan Iovanna; Jose Luis Neira; Olga Abian; Adrian Velazquez Campoy; Yi Xia; Bruno Rizzuti; Ling Peng; Gwen Lomberk; Raul Urrutia; Patricia Santofimia-Castaño

Bimodal silencing of the acinar cell-specific mRNA translation repressor PAIP2B defines a poor prognostic subgroup within the classical pancreatic tumor type 双模沉默的腺泡细胞特异性mRNA翻译抑制因子PAIP2B定义了经典胰腺肿瘤类型中一个预后不良的亚群。

Cancer Letters

IF10.1

2025-08-09

PREAI

Eulalie Corre; Amandine Alard; Catherine Marbœuf; Charline Lasfargues; Sandra Dailhau; Yuna Blum; Rémy Nicolle; Juan Iovanna; Nelson Dusetti; Stéphane Pyronnet

Correction: Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E 更正：热休克蛋白27通过eIF4E使前列腺癌细胞对雄激素剥夺和化疗产生抗性。

Oncogene

IF7.3

2025-08-07

OAAI

C. Andrieu; D. Taieb; V. Baylot; S. Ettinger; P. Soubeyran; A. De-Thonel; C. Nelson; C. Garrido; A. So; L. Fazli; F. Bladou; M. Gleave; J. L. Iovanna; P. Rocchi

Understanding the heterogeneity of pancreatic ductal adenocarcinoma 理解胰腺导管腺癌的异质性

Translational Oncology

IF4.1

2025-07-22

PREAI

Juan Iovanna; Nicolas Fraunhoffer; Raul Urrutia; Nelson Dusetti

The intrinsically disordered protein NUPR1 binds to phospholipids 内在无序蛋白NUPR1结合磷脂

Protein Science

IF5.2

2025-07-21

OAAI

Matías Estaras; Bruno Rizzuti; A. Marcela Giudici; José A. Poveda; Juan L. Iovanna; Patricia Santofimia-Castaño; José L. Neira

KRAS inhibition reverses chemotherapy resistance promoted by therapy-induced senescence-like in pancreatic ductal adenocarcinoma KRAS抑制逆转了由治疗诱导的类衰老促进的胰腺导管腺癌的化疗耐药性。

TRANSLATIONAL ONCOLOGY

IF4.1

2025-07-01

OAAI

Abuelafia, Analia Meilerman; Santofimia-Castano, Patricia; Estaras, Matias; Grasso, Daniel; Chuluyan, Eduardo; Lomberk, Gwen; Urrutia, Raul; Dusetti, Nelson; Fraunhoffer, Nicolas; Iovanna, Juan

Organosilicon molecules bind to the intrinsically disordered protein NUPR1 by clamping its hot-spots 有机硅分子通过夹持其热点区域与固有非结构蛋白NUPR1结合

Archives of Biochemistry and Biophysics

IF3

2025-06-19

PREAI

Laura F. Peña; Matías Estaras; Paula González-Andrés; Carlos Díez-Poza; Bruno Rizzuti; Olga Abian; Adrian Velazquez-Campoy; Juan L. Iovanna; Patricia Santofimia-Castaño; José L. Neira; Asunción Barbero

Medical management of pancreatic cancer: from personalization to broadening treatment strategies 胰腺癌的医学管理：从个体化到拓展治疗策略

Cancer Treatment Reviews

IF10.5

2025-05-31

OAAI

Nelson Dusetti; Jean Baptiste Bachet; Brice Chanez; Cindy Neuzillet; Louis de Mestier; Nicolas Williet; Nicolas Frauhoffer; Remy Nicolle; Alice Boilève; Anthony Turpin; Raphaël Rodriguez; Jérôme Cros; Juan Iovanna; Pascal Hammel

E-Cadherin Is a Structuring Component of Invadopodia in Pancreatic Cancer E-Cadherin 是胰腺癌侵袭小体的一种结构成分。

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IF4.2

2025-05-14

OAAI

Dobric, Aurelie; Germain, Sebastien; Silvy, Francoise; Bonier, Renate; Audebert, Stephane; Camoin, Luc; Dusetti, Nelson; Soubeyran, Philippe; Iovanna, Juan; Rigot, Veronique; Andre, Frederic

Activation of lysosomal iron triggers ferroptosis in cancer 溶酶体铁的激活触发癌细胞的铁死亡

NATURE

IF48.5

2025-05-07

OAAI

Caneque, Tatiana; Baron, Leeroy; Mueller, Sebastian; Carmona, Alanis; Colombeau, Ludovic; Versini, Antoine; Solier, Stephanie; Gaillet, Christine; Sindikubwabo, Fabien; Sampaio, Julio L.; Sabatier, Marie; Mishima, Eikan; Picard-Bernes, Armel; Syx, Laurene; Servant, Nicolas; Lombard, Berangere; Loew, Damarys; Zheng, Jiashuo; Proneth, Bettina; Thoidingjam, Leishemba K.; Grimaud, Laurence; Fraser, Cameron S.; Szylo, Krystina J.; Kazarian, Emma Der; Bonnet, Caroline; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe; Santofimia-Castano, Patricia; Estaras, Matias; Dusetti, Nelson; Iovanna, Juan Lucio; Cunha, Antonio Sa; Pittau, Gabriella; Hammel, Pascal; Tzanis, Dimitri; Bonvalot, Sylvie; Watson, Sarah; Upadhyay, Aditya; Pratt, Derek A.; Freitas, Florencio Porto; Angeli, Jose Pedro Friedmann; Stockwell, Brent R.; Conrad, Marcus; Ubellacker, Jessalyn M.

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E 热休克蛋白27通过eIF4E赋予前列腺癌细胞对雄激素剥夺和化学疗法的抗性。

ONCOGENE

IF7.3

2025-04-10

PREAI

Andrieu, C.; Taieb, D.; Baylot, V.; Ettinger, S.; Soubeyran, P.; De-Thonel, A.; Nelson, C.; Garrido, C.; So, A.; Fazli, L.; Bladou, F.; Gleave, M.; Iovanna, J. L.; Rocchi, P.

Nuclear Galectin-1 promotes KRAS- dependent activation of pancreatic cancer stellate cells 核半乳凝素-1促进KRAS依赖性胰腺癌星状细胞激活

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-04-02

OAAI

Vinaixa, Judith; Martinez-Bosch, Neus; Gibert, Joan; Manero-Ruperez, Noemi; Santofimia-Castano, Patricia; Baudou, Federico G.; Vera, Renzo E.; Pease, David R.; Iglesias, Mar; Sen, Sandhya; Wang, Xiyin; Almada, Luciana L.; Marks, David L.; Moreno, Mireia; Iovanna, Juan L.; Rabinovich, Gabriel A.; Navarro, Pilar

The pancreatic tumor microenvironment of treatment-naïve patients causes a functional shift in γδ T cells, impairing their anti-tumoral defense 初治患者的胰腺肿瘤微环境导致 γ δ T细胞的功能转变，损害其抗肿瘤防御

ONCOIMMUNOLOGY

IF6.3

2025-02-13

OAAI

Lo Presti, Elena; Cupaioli, Francesca; Scimeca, Daniela; Unti, Elettra; Di Martino, Vincenzo; Daidone, Rossella; Amata, Michele; Scibetta, Nunzia; Soucie, Erinn; Meraviglia, Serena; Iovanna, Juan; Dusetti, Nelson; De Gaetano, Andrea; Merelli, Ivan; Di Mitri, Roberto

研究方向