David Veesler - Publications, H-index & Citations

David Veesler

university of washington

82H指数

330论文数

4.6W被引数

收录论文 90

发表时间

TMPRSS2-mediated coronavirus spike activation and inhibition TMPRSS2介导的冠状病毒刺突蛋白激活与抑制

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-04-28

OAAI

Matthew McCallum; James Brett Case; Jack T. Brown; Young-Jun Park; Jimin Lee; Emmajay Sutherland; Anupriya Aggarwal; Cecily Gibson; Florian A. Lempp; Cameron Stewart; M. Alejandra Tortorici; Shilpa Sanapala; Jun Siong Low; Daniel Asarnow; Dana Bohan; Exequiel Dellota; Benjamin Merz; Bhavna Chawla; Swagata Kar; Antonio Lanzavecchia; Federica Sallusto; Nicholas M. Riley; Stuart Turville; Lisa Purcell; Michael S. Diamond; David Veesler

A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses 一种稳定的MERS-CoV铁蛋白纳米颗粒疫苗可诱导强烈的保护性中和抗体应答

Nature Communications

IF15.7

2026-02-05

OAAI

Abigail E. Powell; Hannah Caruso; Soyoon Park; Jui-Lin Chen; Jessica O’Rear; Brian J. Ferrer; Daniel J. Stieh; Adam M. Weiss; David M. Belnap; Audrey Walker; Anneliese Bruening; Airn Hartwig; Kaitlin R. Sprouse; Amin Addetia; Abeer N. Alshukairi; Vida Ahyong; Cristy S. Dougherty; David Veesler; Richard Bowen; Julie E. Ledgerwood; Michael S. Kay; Payton A.-B. Weidenbacher; Brad A. Palanski

The computationally designed TRI2-2 miniprotein inhibitor protects against multiple SARS-CoV-2 Omicron variants 计算设计的TRI2-2微型蛋白抑制剂可保护免受多种SARS-CoV-2奥密克戎变体侵害

Communications Biology

IF5.1

2026-01-10

OAAI

Jimin Lee; James Brett Case; Young-Jun Park; Rashmi Ravichandran; Daniel Asarnow; M. Alejandra Tortorici; Jack T. Brown; Shilpa Sanapala; Lauren Carter; David Baker; Michael S. Diamond; David Veesler

The unique architecture of umbrella toxins permits a two-tiered molecular bet-hedging strategy for interbacterial antagonism 伞形毒素的独特结构使其能够实现一种分级的分子对冲策略，用于细菌间的拮抗作用。

Cell

IF42.5

2025-12-02

OAAI

Qinqin Zhao; Jiri Vlach; Young-Jun Park; Yongjun Tan; Savannah K. Bertolli; Pooja Srinivas; Pinyu Liao; Connor R. Fitzpatrick; Jeffery L. Dangl; Parastoo Azadi; Frank DiMaio; S. Brook Peterson; Dapeng Zhang; David Veesler; Joseph D. Mougous

Potent neutralization of Marburg virus by a vaccine-elicited antibody 疫苗诱导的抗体对马尔堡病毒的中和作用强效

Nature

IF48.5

2025-11-12

OAAI

Amin Addetia; Lisa Perruzza; Kaitlin Sprouse; Young-Jun Park; Matthew McCallum; Cameron Stewart; Bianca Partini; Jack T. Brown; Alessia Donati; Katja Culap; Alessio Balmelli; Bhavna Chawla; Swagata Kar; Michal Gazi; Kendra Alfson; Yenny Goez-Gazi; Ricardo Carrion; Davide Corti; Fabio Benigni; David Veesler

HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor HKU25分支的MERS相关冠状病毒使用ACE2作为功能受体。

Nature Microbiology

IF19.4

2025-10-30

OAAI

Chen Liu; Young-Jun Park; Cheng-Bao Ma; Risako Gen; Cameron Stewart; Yu-Cheng Sun; Xiao Yang; Mei-Yi Lin; Qing Xiong; Jun-Yu Si; Peng Liu; David Veesler; Huan Yan

Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice 计算设计的mRNA启动的蛋白质纳米颗粒免疫原在 mice 中诱导保护性抗体和T细胞应答

Science Translational Medicine

IF14.6

2025-10-15

PREAI

Grace G. Hendricks; Lilit Grigoryan; Mary Jane Navarro; Nicholas J. Catanzaro; Miranda L. Hubbard; John M. Powers; Melissa Mattocks; Catherine Treichel; Alexandra C. Walls; Jimin Lee; Daniel Ellis; Jing Yang (John) Wang; Suna Cheng; Marcos C. Miranda; Adian Valdez; Cara W. Chao; Sidney Chan; Christine Men; Max R. Johnson; Samantha K. Zepeda; Sebastian Ols; Harold Hui; Sheng-Yang Wu; Victor Lujan; Hiromi Muramatsu; Paulo J.C. Lin; Molly M.H. Sung; Ying K. Tam; Elizabeth M. Leaf; Norbert Pardi; Ralph S. Baric; Bali Pulendran; David Veesler; Alexandra Schäfer; Neil P. King

Safety and immunogenicity of a homologous booster dose of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: 12 months follow-up result of an open-label, non-randomised extension of a phase 1/2 trial GBP510重组蛋白纳米颗粒疫苗（一种SARS-CoV-2疫苗）与AS03佐剂同源加强针的安全性与免疫原性：一项期1/2临床试验开放标签非随机扩展研究的12个月随访结果

International Journal of Infectious Diseases

IF4.3

2025-10-08

OAAI

Joon Young Song; Won Suk Choi; Jung Yeon Heo; Young Rong Kim; Jin Soo Lee; Dong Sik Jung; Shin-Woo Kim; Kyung-Hwa Park; Joong Sik Eom; Su Jin Jeong; Jacob Lee; Ki Tae Kwon; Hee Jung Choi; Jang Wook Sohn; Young Keun Kim; Yoonyeong Lee; Ho Keun Park; Ji Hwa Ryu; Su Jeen Lee; Yong Wook Park; Hun Kim; Francesca Solmi; Maria Angeles Ceregido; Marguerite Koutsoukos; Neil King; David Veesler; Hee Jin Cheong

Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics FCoV-23刺突结构域0的丢失增强了融合性和进入动力学

Nature

IF48.5

2025-07-09

OAAI

M. Alejandra Tortorici; Annette Choi; Cecily A. Gibson; Jimin Lee; Jack T. Brown; Cameron Stewart; Anshu Joshi; Sheri Harari; Isabelle Willoughby; Catherine Treichel; Elizabeth M. Leaf; Jesse D. Bloom; Neil P. King; Christine Tait-Burkard; Gary R. Whittaker; David Veesler

Report SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals 报告SARS-CoV-2 nsp1在哺乳动物中介导广泛的翻译抑制

CELL REPORTS

IF6.9

2025-05-01

OAAI

Gen, Risako; Addetia, Amin; Asarnow, Daniel; Park, Young-Jun; Quispe, Joel; Chan, Matthew C.; Brown, Jack T.; Lee, Jimin; Campbell, Melody G.; Lapointe, Christopher P.; Veesler, David

Functional and antigenic landscape of the Nipah virus receptor-binding protein 尼帕病毒受体结合蛋白的功能与抗原性图谱

CELL

IF42.5

2025-05-01

OAAI

Larsen, Brendan B.; McMahon, Teagan; Brown, Jack T.; Wang, Zhaoqian; Radford, Caelan E.; Crowe Jr, James E.; Veesler, David; Bloom, Jesse D.

Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV

CELL REPORTS

IF6.9

2024-12-01

OAAI

Chao, Cara W.; Sprouse, Kaitlin R.; Miranda, Marcos C.; Catanzaro, Nicholas J.; Hubbard, Miranda L.; Addetia, Amin; Stewart, Cameron; Brown, Jack T.; Dosey, Annie; Valdez, Adian; Ravichandran, Rashmi; Hendricks, Grace G.; Ahlrichs, Maggie; Dobbins, Craig; Hand, Alexis; Mcgowan, Jackson; Simmons, Boston; Treichel, Catherine; Willoughby, Isabelle; Walls, Alexandra C.; Mcguire, Andrew T.; Leaf, Elizabeth M.; Baric, Ralph S.; Schafer, Alexandra; Veesler, David; King, Neil P.

Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens RBD纳米颗粒和融合前稳定的刺突免疫原对SARS-CoV-2变体的有效中和

NPJ VACCINES

IF6.5

2024-10-08

OAAI

Miranda, Marcos C.; Kepl, Elizabeth; Navarro, Mary Jane; Chen, Chengbo; Johnson, Max; Sprouse, Kaitlin R.; Stewart, Cameron; Palser, Anne; Valdez, Adian; Pettie, Deleah; Sydeman, Claire; Ogohara, Cassandra; Kraft, John C.; Pham, Minh; Murphy, Michael; Wrenn, Sam; Fiala, Brooke; Ravichandran, Rashmi; Ellis, Daniel; Carter, Lauren; Corti, Davide; Kellam, Paul; Lee, Kelly; Walls, Alexandra C.; Veesler, David; King, Neil P.

Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans

CELL REPORTS

IF6.9

2024-08-01

OAAI

Addetia, Amin; Stewart, Cameron; Seo, Albert J.; Sprouse, Kaitlin R.; Asiri, Ayed Y.; Al-Mozaini, Maha; Memish, Ziad A.; Alshukairi, Abeer N.; Veesler, David

A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines

NATURE COMMUNICATIONS

IF15.7

2024-06-28

OAAI

Lee, Jimin; Stewart, Cameron; Schaefer, Alexandra; Leaf, Elizabeth M.; Park, Young-Jun; Asarnow, Daniel; Powers, John M.; Treichel, Catherine; Sprouse, Kaitlin R.; Corti, Davide; Baric, Ralph; King, Neil P.; Veesler, David

Structure and design of Langya virus glycoprotein antigens 琅琊病毒糖蛋白抗原的结构与设计

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-09

OAAI

Wang, Zhaoqian; Mccallum, Matthew; Yan, Lianying; Gibson, Cecily A.; Sharkey, William; Park, Young - Jun; V. Dang, Ha; Amaya, Moushimi; Person, Ashley; Broder, Christopher C.; Veeslera, David

Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates 靶向Nipah病毒融合糖蛋白的交叉反应性mAb的治疗性给药可保护非人类灵长类动物

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-04-03

PREAI

Zeitlin, Larry; Cross, Robert W.; Woolsey, Courtney; West, Brandyn R.; Borisevich, Viktoriya; Agans, Krystle N.; Prasad, Abhishek N.; Deer, Daniel J.; Stuart, Lauren; Mccavitt-Malvido, Maria; Kim, Do H.; Pettitt, James; Crowe Jr, James E.; Whaley, Kevin J.; Veesler, David; Dimitrov, Antony; Abelson, Dafna M.; Geisbert, Thomas W.; Broder, Christopher C.

Persistent immune imprinting occurs after vaccination with the COVID-19 XBB.1.5 mRNA booster in humans

IMMUNITY

IF26.3

2024-04-01

OAAI

Tortorici, M. Alejandra; Addetia, Amin; Seo, Albert J.; Brown, Jack; Sprouse, Kaiti; Logue, Jenni; Clark, Erica; Franko, Nicholas; Chu, Helen; Veesler, David

Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features

NATURE COMMUNICATIONS

IF15.7

2024-03-11

OAAI

Magaret, Craig A.; Li, Li; deCamp, Allan C.; Rolland, Morgane; Juraska, Michal; Williamson, Brian D.; Ludwig, James; Molitor, Cindy; Benkeser, David; Luedtke, Alex; Simpkins, Brian; Heng, Fei; Sun, Yanqing; Carpp, Lindsay N.; Bai, Hongjun; Dearlove, Bethany L.; Giorgi, Elena E.; Jongeneelen, Mandy; Brandenburg, Boerries; McCallum, Matthew; Bowen, John E.; Veesler, David; Sadoff, Jerald; Gray, Glenda E.; Roels, Sanne; Vandebosch, An; Stieh, Daniel J.; Le Gars, Mathieu; Vingerhoets, Johan; Grinsztejn, Beatriz; Goepfert, Paul A.; de Sousa, Leonardo Paiva; Silva, Mayara Secco Torres; Casapia, Martin; Losso, Marcelo H.; Little, Susan J.; Gaur, Aditya; Bekker, Linda-Gail; Garrett, Nigel; Truyers, Carla; Van Dromme, Ilse; Swann, Edith; Marovich, Mary A.; Follmann, Dean; Neuzil, Kathleen M.; Corey, Lawrence; Greninger, Alexander L.; Roychoudhury, Pavitra; Hyrien, Ollivier; Gilbert, Peter B.

Antigen spacing on protein nanoparticles influences antibody responses to vaccination

CELL REPORTS

IF6.9

2023-12-01

OAAI

Ellis, Daniel; Dosey, Annie; Boyoglu-Barnum, Seyhan; Park, Young -Jun; Gillespie, Rebecca; Syeda, Hubza; Hutchinson, Geoffrey B.; Tsybovsky, Yaroslav; Murphy, Michael; Pettie, Deleah; Matheson, Nick; Chan, Sidney; Ueda, George; Fallas, Jorge A.; Carter, Lauren; Graham, Barney S.; Veesler, David; Kanekiyo, Masaru; King, Neil P.

研究方向