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K

Kieran Wynne

university college dublin

35H指数
161论文数
4.1K被引数
收录论文 72
发表时间
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Reduced PRC2 function causes asparaginase resistance in T-ALL by decreasing WNT pathway activityPRC2功能的降低通过降低WNT通路活性导致T-ALL对门冬酰胺酶产生耐药性。
errBlood Advances
IF7.1
err2025-12-04
err0
errOAAI
errThomas Lefeivre; Theodora-Ioana Grosu; Cosmin Tudose; Luke Jones; Theresa E. León; Kieran Wynne; Giorgio Oliviero; Owen P. Smith; Amélie Trinquand; Marc R. Mansour; Colm J. Ryan; Jonathan Bond
err分享
err收藏
Oxphos targeting of MYCN-amplified neuroblastomaMYCN扩增神经母细胞瘤的氧化磷酸化靶向
errFrontiers in Oncology
IF3.3
err2025-10-24
err0
errOAAI
errSoraya Epp; Donagh Egan; Evon Poon; Amirah Adlina Abdul Aziz; Kieran Wynne; Louis Chesler; Melinda Halasz†; Walter Kolch†
err分享
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Response to Nutrient Stress in the Industrial Model Bacterium Cupriavidus necator: A Thermal Proteome Profiling (TPP) Investigation工业模式细菌Cupriavidus necator对营养胁迫的响应：一项热蛋白质组分析（TPP）研究
errPROTEOMICS
IF3.9
err2025-09-16
err0
errOAAI
errKate McKeever; Jia-Lynn Tham; Manuel Bruch; Tania Narancic; Kevin O’ Connor; Swathi Ramachandra Upadhya; Colm Ryan; Eugene T. Dillon; Kieran Wynne; Gerard Cagney
err分享
err收藏
Inhibition of HDAC6 alters fumarate hydratase activity and mitochondrial structure抑制HDAC6改变延胡索酸水合酶活性和线粒体结构
errNature Communications
IF15.7
err2025-07-28
err0
errOAAI
errAndrew Roe; Catríona M. Dowling; Cian D’Arcy; Daniel Alencar Rodrigues; Yu Wang; Matthew Hiller; Carl Keogh; Kate E. R. Hollinshead; Massimiliano Garre; Brenton Cavanagh; Kieran Wynne; Tianyan Liu; Zhixing Chen; Emma Kerr; Marie McIlroy; Jochen H. M. Prehn; Ingmar Schoen; Tríona Ní Chonghaile
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Assessment of the molecular mechanisms of drug-induced hidden cardiotoxicity by a multi-omics approach: The example of rofecoxib采用多组学方法评估药物诱导的隐性心脏毒性的分子机制：以rofecoxib为例
errBritish Journal of Pharmacology
IF7.7
err2025-06-18
err0
errOAAI
errBennet Y. Weber; Gábor B. Brenner; Barnabás Váradi; Bence Ágg; Csenger Kovácsházi; Olivér M. Balogh; Donagh Egan; Kieran Wynne; David Matallanas; Rainer Schulz; Péter Ferdinandy; Zoltán Giricz; Anikó Görbe
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Saturated fat exacerbates mitochondrial dysfunction through remodelling of ATP production and inflammation in Barrett's oesophagus compared to monounsaturated fat, particularly in contrast to oesophageal adenocarcinoma饱和脂肪通过重塑ATP产生和炎症，加剧Barrett's oesophagus中的线粒体功能障碍，与单不饱和脂肪相比，尤其在对比食管腺癌时。
errNEOPLASIA
IF7.7
err2025-06-17
err0
PREAI
errMitchelson, Kathleen A. J.; O'Connell, Fiona; Wynne, Kieran; Matallanas, David; O'Sullivan, Jacintha; Roche, Helen M.
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Proteomic compensation by paralogs preserves protein interaction networks after gene loss in cancer同源基因的蛋白质组补偿在癌症基因丢失后维持了蛋白质相互作用网络
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2025-05-28
err0
errOAAI
errVenkatesh, Anjan; Quinn, Niall; Upadhya, Swathi Ramachandra; De Kegel, Barbara; Bolado Carrancio, Alfonso; Lefeivre, Thomas; Dennler, Olivier; Wynne, Kieran; von Kriegsheim, Alexander; Ryan, Colm J.
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De novo DUOX2 expression in neutrophil subsets shapes the pathogenesis of intestinal disease中性粒细胞亚群中从头DUOX2表达塑造肠道疾病的发病机制
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2025-05-06
err0
errOAAI
errSingh, Ashish K.; Ainciburu, Marina; Wynne, Kieran; Bhat, Sajad A.; Blanco, Alfonso; Tzani, Ioanna; Akiba, Yasutada; Lalor, Stephen J.; Kaunitz, Jonathan; Bourke, Billy; Kelly, Vincent P.; Doherty, Glen A.; Zerbe, Christa S.; Clarke, Colin; Hussey, Seamus; Knaus, Ulla G.
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Rivaroxaban, in combination with low-dose aspirin, is associated with a reduction in proinflammatory and prothrombotic circulating vesicle signatures in patients with cardiovascular disease
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2025-02-01
err1
errOAAI
errWeiss, Luisa; O'Doherty, Aideen; Uhrig, Wido; Szklanna, Paulina B.; Hong-Minh, Molly; Wynne, Kieran; Blanco, Alfonso; Zivny, Jan; Passos, Valeria Lima; Kevane, Barry; Murphy, Sean; Ainle, Fionnuala Ni; O'Donnell, Martin; Maguire, Patricia B.
err分享
err收藏
Using Structure-Based Modeling to Identify Effective Drug Combinations in RAS-Mutant Acute Myeloid Leukemia利用结构为基础的建模方法识别RAS突变急性髓系白血病中的有效药物组合
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errJones, Luke; Rukhlenko, Oleksii; Dias, Tania; Carmody, Ciardha; Wynne, Kieran; Kholodenko, Boris; Bond, Jonathan
err分享
err收藏
Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells
errCELL REPORTS
IF6.9
err2024-09-01
err2
errOAAI
errSevrin, Thomas; Imoto, Hiroaki; Robertson, Sarah; Rauch, Nora; Dyn'ko, Uscinnia; Koubova, Katerina; Wynne, Kieran; Kolch, Walter; Rukhlenko, Oleksii S.; Kholodenko, Boris N.
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Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2024-07-01
err1
errOAAI
errEyrne, Jonah F.; Healy, Colm; Fo, Melanie; Heurich, Meike; Susai, Subash Raj; Mongan, David; Wynne, Kieran; Kodosaki, Eleftheria; Woods, Scott W.; Cornblatt, Barbara A.; Stone, William S.; Mathalon, Daniel H.; Bearden, Carrie E.; Cadenhead, Kristin S.; Addington, Jean; Walker, Elaine F.; Cannon, Tyrone D.; Cannon, Mary; Jeffries, Clark; Perkins, Diana; Cotter, David R.
err分享
err收藏
Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles
errSCIENTIFIC REPORTS
IF3.9
err2024-05-26
err3
errOAAI
errKovacshazi, Csenger; Hambalko, Szabolcs; Sayour, Nabil V.; Gergely, Tamas G.; Brenner, Gabor B.; Pelyhe, Csilla; Kapui, Dora; Weber, Bennet Y.; Hultenschmidt, Alexander L.; Pallinger, Eva; Buzas, Edit I.; Zolcsak, Adam; Kiss, Balint; Bozo, Tamas; Csanyi, Csilla; Kosa, Nikolett; Kellermayer, Miklos; Farkas, Robert; Karvaly, Gellert B.; Wynne, Kieran; Matallanas, David; Ferdinandy, Peter; Giricz, Zoltan
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Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms触珠蛋白在临床精神病高危人群中的差异表达及其与整体功能和临床症状的关系
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2024-03-01
err1
errOAAI
errHealy, Colm; Byrne, Jonah; Suasi, Subash Raj; Focking, Melanie; Mongan, David; Kodosaki, Eleftheria; Heurich, Meike; Cagney, Gerard; Wynne, Kieran; Bearden, Carrie E.; Woods, Scott W.; Cornblatt, Barbara; Mathalon, Daniel; Stone, William; Cannon, Tyrone D.; Addington, Jean; Cadenhead, Kristin S.; Perkins, Diana; Jeffries, Clark; Cotter, David
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err收藏
Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study预测临床高危个体向精神病转变的蛋白质组学生物标志物: 一项多队列模型开发研究
errSCHIZOPHRENIA BULLETIN
IF4.8
err2024-01-19
err1
errOAAI
errByrne, Jonah F.; Healy, Colm; Focking, Melanie; Susai, Subash Raj; Mongan, David; Wynne, Kieran; Kodosaki, Eleftheria; Heurich, Meike; de Haan, Lieuwe; Hickie, Ian B.; Smesny, Stefan; Thompson, Andrew; Markulev, Connie; Young, Alison Ruth; Schafer, Miriam R.; Riecher-Rossler, Anita; Mossaheb, Nilufar; Berger, Gregor; Schlogelhofer, Monika; Nordentoft, Merete; Chen, Eric Y. H.; Verma, Swapna; Nieman, Dorien H.; Woods, Scott W.; Cornblatt, Barbara A.; Stone, William S.; Mathalon, Daniel H.; Bearden, Carrie E.; Cadenhead, Kristin S.; Addington, Jean; Walker, Elaine F.; Cannon, Tyrone D.; Cannon, Mary; McGorry, Pat; Amminger, Paul; Cagney, Gerard; Nelson, Barnaby; Jeffries, Clark; Perkins, Diana; Cotter, David R.
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err收藏
Investigating serum extracellular vesicles in Cystic Fibrosis
errJOURNAL OF CYSTIC FIBROSIS
IF6
err2023-07-01
err4
errOAAI
errTrappe, Anne; Lakkappa, Navya; Carter, Suzanne; Dillon, Eugene; Wynne, Kieran; Mckone, Edward; Mcnally, Paul; Coppinger, Judith A.
err分享
err收藏
The protein and miRNA profile of plasma extracellular vesicles (EVs) can distinguish feline mammary adenocarcinoma patients from healthy feline controls
errSCIENTIFIC REPORTS
IF3.9
err2023-06-06
err2
errOAAI
errHoward, Jane; Browne, John; Bollard, Stephanie; Peters, Susan; Sweeney, Ciara; Wynne, Kieran; Potter, Shirley; McCann, Amanda; Kelly, Pamela
err分享
err收藏
Analysis of context-specific KRAS-effector (sub) complexes in Caco-2 cells
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-03-09
err5
errOAAI
errTernet, Camille; Junk, Philipp; Sevrin, Thomas; Catozzi, Simona; Wa, Erik; Heldin, Johan; Oliviero, Giorgio; Wynne, Kieran; Kiel, Christina
err分享
err收藏
Disease-Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein-Protein Interaction Networks
errBIOENGINEERING-BASEL
IF3.7
err2022-12-21
err0
errOAAI
errD'Arcy, Cian; Bass, Olivia; Junk, Philipp; Sevrin, Thomas; Oliviero, Giorgio; Wynne, Kieran; Halasz, Melinda; Kiel, Christina
err分享
err收藏
Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis补体和凝血蛋白介导对omega-3脂肪酸的临床反应的证据: 在精神病临床高危受试者中进行的基于质谱的研究
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2022-10-28
err7
errOAAI
errSusai, Subash Raj; Healy, Colm; Mongan, David; Heurich, Meike; Byrne, Jonah F.; Cannon, Mary; Cagney, Gerard; Wynne, Kieran; Markulev, Connie; Schafer, Miriam R.; Berger, Maximus; Mossaheb, Nilufar; Schlogelhofer, Monika; Smesny, Stefan; Hickie, Ian B.; Berger, Gregor E.; Chen, Eric Y. H.; de Haan, Lieuwe; Nieman, Dorien H.; Nordentoft, Merete; Riecher-Rossler, Anita; Verma, Swapna; Street, Rebekah; Thompson, Andrew; Yung, Alison Ruth; Nelson, Barnaby; McGorry, Patrick D.; Focking, Melanie; Amminger, G. Paul; Cotter, David
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研究方向

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