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R

Richard Lee

St Jude Children's Research Hospital
H指数:91
被引数:3.2万

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Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids

结核分枝杆菌通过大量重塑其磷脂组，利用不含磷的脂质克服磷酸盐饥饿。

Nature Communications
IF15.7
2025-11-200
OAAI
Robert M. Gray; Debbie M. Hunt; Mariana Silva dos Santos; Jiuyu Liu; Aleksandra Agapova; Angela Rodgers; Antony Fearns; Julio Ortiz Canseco; Acely Garza-Garcia; James I. MacRae; Maximiliano G. Gutierrez; Richard E. Lee; Luiz Pedro S. de Carvalho
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus

前药氟苯尼考胺被固有耐药性激活以靶向分枝杆菌脓肿亚种

Nature Microbiology
IF19.4
2025-10-300
OAAI
Gregory A. Phelps; Sinem Kurt; Alexander R. Jenner; Shelby M. Anderson; Thalina D. Jayasinghe; Elizabeth C. Griffith; Carl W. Thompson; Lei Yang; Basil Wicki; Frederick K. Bright; Victoria Loudon; William C. Wright; Ashish Srivastava; Amarinder Singh; Bhargavi Thalluri; Hyunseo Park; Robin B. Lee; Anna K. Wright; Oliver Grant-Chapman; Daryl K. Conner; Brennen T. Troyer; Amy Iverson; Jason Ochoado; Vishwajeeth R. Pagala; Long Wu; Stephanie Byrum; Yingxue Fu; Zu-Fei Yuan; Anthony A. High; Bettina Schulthess; Jason W. Rosch; Paul Geeleher; Sven N. Hobbie; Lucas Boeck; Bernd Meibohm; Andres Obregon-Henao; Peter Sander; Richard E. Lee
Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria

通过增强革兰氏阴性菌二氢蝶酸合成酶蝶呤结合位点的全细胞靶点结合作用开发嘧啶吡啶嗪类似物

ACS Infectious Diseases
IF3.8
2025-10-200
OAAI
Hannah E. Snoke; Stephanie M. Reeve; Suresh Dharuman; Miranda J. Wallace; Victoria C. Loudon; Ying Zhao; John J. Bowling; Patricia A. Murphy; Brett Waddell; Robin B. Lee; Jürgen B. Bulitta; Richard E. Lee
Validating the SONG-PKD Pain Instrument , a Core Outcome Measure for Pain in ADPKD
KIDNEY INTERNATIONAL REPORTS
IF5.7
2025-02-010
OAAI
Cazzolli, Rosanna; Ju, Angela; Natale, Patrizia; Teixeira-Pinto, Armando; Howell, Martin; Jaure, Allison; Perrone, Ronald D.; Burnette, Eva; Casteleijn, Niek F.; Chapman, Arlene; Craig, Jonathan C.; Eastty, Sarah; Gansevoort, Ron T.; Harris, Tess; Hogan, Marie C.; Horie, Shigeo; Knebelmann, Bertrand; Lee, Richard; Manera, Karine; Mustafa, Reem A.; Sandford, Richard; Rangan, Gopala K.; Sautenet, Benedicte; Viecelli, Andrea K.; Cho, Yeoungjee
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2024-11-060
OAAI
Bauman, Allison A.; Sarathy, Jansy P.; Kaya, Firat; Massoudi, Lisa M.; Scherman, Michael S.; Hastings, Courtney; Liu, Jiuyu; Xie, Min; Brooks, Elizabeth J.; Ramey, Michelle E.; Jones, Isabelle L.; Benedict, Noalani D.; Maclaughlin, Madelyn R.; Miller-Dawson, Jake A.; Waidyarachchi, Samanthi L.; Butler, Michelle M.; Bowlin, Terry L.; Zimmerman, Matthew D.; Lenaerts, Anne J.; Meibohm, Bernd; Gonzalez-Juarrero, Mercedes; Lyons, Michael A.; Dartois, Veronique; Lee, Richard E.; Robertson, Gregory T.
Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2

参与c-degron E3 KLHDC2的旁系同源特异性靶向蛋白质降解的原理

NATURE COMMUNICATIONS
IF15.7
2024-10-120
OAAI
Scott, Daniel C.; Dharuman, Suresh; Griffith, Elizabeth; Chai, Sergio C.; Ronnebaum, Jarrid; King, Moeko T.; Tangallapally, Rajendra; Lee, Chan; Gee, Clifford T.; Yang, Lei; Li, Yong; Loudon, Victoria C.; Lee, Ha Won; Ochoada, Jason; Miller, Darcie J.; Jayasinghe, Thilina; Paulo, Joao A.; Elledge, Stephen J.; Harper, J. Wade; Chen, Taosheng; Lee, Richard E.; Schulman, Brenda A.
Sophisticated natural products as antibiotics

复杂的天然产物作为抗生素

Nature
IF48.5
2024-07-310
PRE
Kim Lewis; Richard E. Lee; Heike Brötz-Oesterhelt; Sebastian Hiller; Marina V. Rodnina; Tanja Schneider; Markus Weingarth; Ingo Wohlgemuth
Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in in vitro media, and novel supplement dosing strategy to mitigate thermal drug degradation

13种 β-内酰胺类和 β-内酰胺酶抑制剂在体外培养基中的综合稳定性分析，以及减轻药物热降解的新型补充给药策略

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2024-03-063
OA
Zhou, Jieqiang; Qian, Yuli; Lang, Yinzhi; Zhang, Yongzhen; Tao, Xun; Moya, Bartolome; Sayed, Alaa R. M.; Landersdorfer, Cornelia B.; Shin, Eunjeong; Werkman, Carolin; Smith, Nicholas M.; Kim, Tae Hwan; Kumaraswamy, Monika; Shin, Beom Soo; Tsuji, Brian T.; Bonomo, Robert A.; Lee, Richard E.; Bulitta, Jurgen B.
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus

开发克服脓肿分枝杆菌天然外排的第二代氨基甲基spectinomycins

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-01-024
OAAI
Phelps, Gregory A.; Cheramie, Martin N.; Fernando, Dinesh M.; Selchow, Petra; Meyer, Christopher J.; Waidyarachchi, Samanthi L.; Dharuman, Suresh; Liu, Jiuyu; Meuli, Michael; Dal Molin, Michael; Killam, Benjamin Y.; Murphy, Patricia A.; Reeve, Stephanie M.; Wilt, Laura A.; Anderson, Shelby M.; Yang, Lei; Lee, Robin B.; Temrikar, Zaid H.; Lukka, Pradeep B.; Meibohm, Bernd; Polikanov, Yury S.; Hobbie, Sven N.; Bottger, Erik C.; Sander, Peter; Lee, Richard E.
Pantothenate Kinase Activation Restores Brain Coenzyme A in a Mouse Model of Pantothenate Kinase-Associated Neurodegeneration

泛酸激酶激活可在泛酸激酶相关的神经变性小鼠模型中恢复脑辅酶a

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
2024-01-014
OAAI
Subramanian, Chitra; Frank, Matthew W.; Sukhun, Rajaa; Henry, Christopher E.; Wade, Anna; Harden, Mallory E.; Rao, Satish; Tangallapally, Rajendra; Yun, Mi-Kyung; White, Stephen W.; Lee, Richard E.; Sinha, Uma; Rock, Charles O.; Jackowski, Suzanne
Deletion of the Duffy Antigen Receptor for Chemokines Impairs Blood Flow Recovery in the Mouse Hindlimb Ischemia Model: Role of CCL11

在小鼠后肢缺血模型中，趋化因子Duffy抗原受体的缺失会损害血流恢复: CCL11的作用

CIRCULATION
IF38.6
2023-11-070
PRE
Aboud, Ghaith; Harb, Ragheb; Kim, David; Goo, Brandee; Ogbi, Mourad; Veerapaneni, Praneet; Chouhaita, Ronnie; Coffey, Philip; Lee, Richard; Hou, Yali; Guha, Avirup; Shi, Hong; Ushio-Fukai, Masuko; Annex, Brian H.; Kim, Ha Won; Weintraub, Neal L.

研究方向

暂未获取到该数据
J
Jiuyu Liu
H 指数:18论文数:68被引数:1,318
B
Bernd Meibohm
H 指数:54论文数:320被引数:1.1万
S
Stephen W. White
H 指数:61论文数:277被引数:1.3万
R
Robin B. Lee
H 指数:20论文数:51被引数:1,439
T
Taosheng Chen
H 指数:50论文数:297被引数:7,732
J
Julian G. Hurdle
H 指数:31论文数:81被引数:3,511
C
Charles O. Rock
H 指数:92论文数:366被引数:2.5万
L
Lei Yang
H 指数:32论文数:113被引数:2,905
M
Michaël Scherman
H 指数:33论文数:96被引数:3,546
M
Mi‐Kyung Yun
H 指数:19论文数:46被引数:1,552