未登录 分享 收藏
Targeting IL6-Edn1-FoxO1 axis enables lung growth in mechanically ventilated newborn mice Hirani, Dharmesh; Selle, Jaco; Wagde, Virta; Klymenko, Oleksiy; Kuiper-Makris, Celien; Danopoulos, Soula; Donato, Michele; Preuss, Stefanie; Preuss, Mark; Mujahid, Sana; Vohlen, Christina; Wulf, Kerstin; Van Koningsbruggen-Rietschel, Silke; Khatri, Purvesh; Wunderlich, Thomas; Koch, Manuel; Rose-John, Stefan; Sucre, Jennifer M. S.; Al-Alam, Denise; Seeger, Werner; Dotsch, Jorg; Bland, Richard D.; Rabinovitch, Marlene; Alcazar, Miguel A. Alejandre 分享 收藏
Blockade of Interleukin-6 Trans-signaling in the Presence of Certain Gut Microbiota Induces Mature-onset Obesity in Mice 特定肠道微生物群存在下，白介素-6转信号通路的阻断可诱导小鼠发生成年期肥胖。 Lanton, Tali; Eidelshtein, Dana; Rachmilewitz, Jacob; Abramovitch, Rinat; Pappo, Orit; Udi, Shiran; Baraghithy, Saja; Tam, Joseph; Perles, Sharon; Williams, Evan; Elgavish, Sharona; Ruppo, Shmuel; Benyamini, Hadar; Mor, Uria; Elinav, Eran; Schmidt-Arras, Dirk; Rehman, Ateequr; Rosenstiel, Philip; Giannou, Anastasios; Huber, Samuel; Rose-John, Stefan; Galun, Eithan; Axelrod, Jonathan H. 分享 收藏
分享 收藏
Type I interferon limits interleukin-6 signalling in SLE through shedding interleukin-6 receptors I型干扰素通过脱落白细胞介素-6受体限制系统性红斑狼疮中的白细胞介素-6信号通路。 Hempel, Martyna; Klapproth, Erik; Krause, Annika; Becker-Pauly, Christoph; Zeissig, Sebastian; Heschel, Babett; Weser, Nadine; Fantana, Julia; Leuchten, Nicolai; Rose-John, Stefan; El-Armouche, Ali; Korb-Pap, Adelheid; Aringer, Martin 分享 收藏
分享 收藏
分享 收藏
A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling Curren, Bodie; Ahmed, Tufael; Rashid, Ridwan B.; Sebina, Ismail; Sikder, Md. Al Amin; Howard, Daniel R.; Alorro, Mariah; Ullah, Md. Ashik; Bissell, Alec; Rahman, Muhammed Mahfuzur; Pearen, Michael A.; Ramm, Grant A.; Varelias, Antiopi; Rose-John, Stefan; Macdonald, Kelli P. A.; Hoelzle, Robert; Cuiv, Paraic O'; Spann, Kirsten M.; Dennis, Paul G.; Phipps, Simon 分享 收藏
Cell-autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment Sternberg, Christina; Raigel, Martin; Limberger, Tanja; Trachtova, Karolina; Schlederer, Michaela; Lindner, Desiree; Kodajova, Petra; Yang, Jiaye; Ziegler, Roman; Kalla, Jessica; Stoiber, Stefan; Dey, Saptaswa; Zwolanek, Daniela; Neubauer, Heidi A.; Oberhuber, Monika; Redmer, Torben; Hejret, Vaclav; Tichy, Boris; Tomberger, Martina; Harbusch, Nora S.; Pencik, Jan; Tangermann, Simone; Bystry, Vojtech; Persson, Jenny L.; Egger, Gerda; Pospisilova, Sarka; Eferl, Robert; Wolf, Peter; Sternberg, Felix; Hogler, Sandra; Lagger, Sabine; Rose-John, Stefan; Kenner, Lukas 分享 收藏
IL6-ET1 signaling inhibits alveolar growth through FoxO1-dependent AT2 survival in mechanically ventilated newborn mice Kuiper-Makris, Centina; Hirani, Dharmesh; Wagde, Virta; Selle, Jaco; Klymenko, Oleksiy; Donato, Michele; Preuss, Stefanie; Kaschwich, Mark; Mujahid, Sana; Vohlen, Christina; Wilke, Rebecca; Wulf, Kerstin; Van-Koningsbruggen-Rietschel, Silke; Khatri, Parvesh; Koch, Manuel; Rose-John, Stefan; Seeger, Werner; Doetsch, Jorg; Bland, Richard D.; Rabinovitch, Marlene; Alcazar, Miguel Angel Alejandre 分享 收藏
Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2-infected mice and reduces endotheliopathy Rodriguez-Hernandez, Maria Angeles; Baena-Bustos, Mercedes; Carneros, David; Zurita-Palomo, Carola; Munoz-Pinillos, Pablo; Millan, Jaime; Padillo, Francisco Javier; Smerdou, Cristian; von Kobbe, Cayetano; Rose-John, Stefan; Bustos, Matilde 分享 收藏
Activation of gp130 signaling in T cells drives TH17-mediated multi-organ autoimmunity Baumgartner, Francis; Bamopoulos, Stefanos A.; Faletti, Laura; Hsiao, Hsiang-Jung; Holz, Maximilian; Gonzalez-Menendez, Irene; Boldo, Llorenc; Horne, Arik; Gosavi, Sanket; Oezerdem, Ceren; Singh, Nikita; Liebig, Sven; Ramamoorthy, Senthilkumar; Lehmann, Malte; Demel, Uta; Kuehl, Anja A.; Wartewig, Tim; Ruland, Juergen; Wunderlich, Frank T.; Schick, Markus; Walther, Wolfgang; Rose-John, Stefan; Haas, Simon; Quintanilla-Martinez, Leticia; Feske, Stefan; Ehl, Stephan; Glauben, Rainer; Keller, Ulrich 分享 收藏
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway STAT3/LKB1通过调控mTORC1/CREB通路调控转移性前列腺癌 Pencik, Jan; Philippe, Cecile; Schlederer, Michaela; Atas, Emine; Pecoraro, Matteo; Grund-Groeschke, Sandra; Li, Wen (Jess); Tracz, Amanda; Heidegger, Isabel; Lagger, Sabine; Trachtova, Karolina; Oberhuber, Monika; Heitzer, Ellen; Aksoy, Osman; Neubauer, Heidi A.; Wingelhofer, Bettina; Orlova, Anna; Witzeneder, Nadine; Dillinger, Thomas; Redl, Elisa; Greiner, Georg; D'Andrea, David; Ostman, Johnny R.; Tangermann, Simone; Hermanova, Ivana; Schaefer, Georg; Sternberg, Felix; Pohl, Elena E.; Sternberg, Christina; Varady, Adam; Horvath, Jaqueline; Stoiber, Dagmar; Malcolm, Tim I.; Turner, Suzanne D.; Parkes, Eileen E.; Hantusch, Brigitte; Egger, Gerda; Rose-John, Stefan; Poli, Valeria; Jain, Suneil; Armstrong, Chris W. D.; Hoermann, Gregor; Goffin, Vincent; Aberger, Fritz; Moriggl, Richard; Carracedo, Arkaitz; McKinney, Cathal; Kennedy, Richard D.; Klocker, Helmut; Speicher, Michael R.; Tang, Dean G.; Moazzami, Ali A.; Heery, David M.; Hacker, Marcus; Kenner, Lukas 分享 收藏
The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation Gatsiou, Aikaterini; Tual-Chalot, Simon; Napoli, Matteo; Ortega-Gomez, Almudena; Regen, Tommy; Badolia, Rachit; Cesarini, Valeriana; Garcia-Gonzalez, Claudia; Chevre, Raphael; Ciliberti, Giorgia; Silvestre-Roig, Carlos; Martini, Maurizio; Hoffmann, Jedrzej; Hamouche, Rana; Visker, Joseph R.; Diakos, Nikolaos; Wietelmann, Astrid; Silvestris, Domenico Alessandro; Georgiopoulos, Georgio; Moshfegh, Ali; Schneider, Andre; Chan, Wei; Guenther, Stefan; Backs, Johanne; Kwak, Shin; Selzman, Craig H.; Stamatelopoulos, Kimon; Rose-John, Stefan; Trautwein, Christian; Spyridopoulos, Ioakim; Braun, Thomas; Waisman, Ari; Gallo, Angela; Drakos, Stavros G.; Dimmeler, Stefanie; Sperandio, Markus; Soehnlein, Oliver; Stellos, Konstantinos 分享 收藏
分享 收藏
Cell-Autonomous Constitutive gp130 Signaling in T Cells Amplifies TH17 Cell Responses and Causes Severe Lung Inflammation Heinig, Lisa Charlotte; Huth, Emily Valentina Madelaine; Yan, Karsten; Schumacher, Neele; Nawrocki, Mikolaj; Lory, Niels Christian; Bradtke, Peter; Bertram, Tabea; Rattay, Guido; Schmid, Joanna; Huber, Samuel; Wiech, Thorsten; Schmidt-Arras, Dirk; Rose-John, Stefan; Mittruecker, Hans-Willi 分享 收藏
Constitutive Activation of gp130 in T Cells Results in Senescence and Premature Aging T细胞中gp130的组成性激活导致衰老和过早衰老 Rafii, Puyan; Reusswig, Friedrich; Werner, Julia; Xu, Haifeng; Lang, Philpp A.; Rose-John, Stefan; Gorressen, Simone; Alter, Christina; Schrader, Jurgen; Herebian, Diran; Floss, Doreen M.; Elvers, Margitta; Piekorz, Roland P.; Scheller, Jurgen; Behnke, Kristina 分享 收藏
L1 is sequentially processed by two differently activated metalloproteases and presenilin/γ-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth Maretzky, T; Schulte, M; Ludwig, A; Rose-John, S; Blobel, C; Hartmann, D; Altevogt, P; Saftig, P; Reiss, K 分享 收藏
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130 Muller, Stephan A.; Shmueli, Merav D.; Feng, Xiao; Tushaus, Johanna; Schumacher, Neele; Clark, Ryan; Smith, Brad E.; Chi, An; Rose-John, Stefan; Kennedy, Matthew E.; Lichtenthaler, Stefan F. 分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
