未登录 Aminoadipate-semialdehyde synthase, a potential target for substrate reduction therapy in glutaric aciduria type 1 氨基己二酸半醛合成酶，戊二酸尿症I型的底物减少疗法潜在靶点 Saad, Celine; Jung-Klawitter, Sabine; Dimitrov, Bianca; Aguilar-Pimentel, Juan Antonio; Becker, Lore; da Silva-Buttkus, Patricia; Dragano, Nathalia R. V.; Garrett, Lillian; Holter, Sabine M.; Rathkolb, Birgit; Sanz-Moreno, Adrian; Spielmann, Nadine; Fuchs, Helmut; Gailus-Durner, Valerie; Schaaf, Christian P.; la Marca, Giancarlo; Damiano, Roberta; Lefeber, Dirk J.; Engelke, Udo; de Angelis, Martin Hrabe; Houten, Sander M.; Kolker, Stefan 分享 收藏
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Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice 巴瑞替尼和洛纳法尔尼布协同靶向早老蛋白和炎症，改善早衰小鼠的寿命和健康。 Krueger, Peter; Schroll, Moritz; Fenzl, Felix Quirin; Hartinger, Ramona; Lederer, Eva-Maria; Goerlach, Agnes; Gordon, Leslie B.; Cavalcante, Paola; Iacomino, Nicola; Rathkolb, Birgit; Pimentel, Juan Antonio Aguilar; Oestereicher, Manuela; Spielmann, Nadine; Wolf, Cordula Maria; de Angelis, Martin Hrabe; Djabali, Karima 分享 收藏
Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita Ten1在小鼠中的缺失诱导端粒缩短，并模拟人类先天性角化不良 Sanz-Moreno, Adrian; Becker, Lore; Xie, Kan; da Silva-Buttkus, Patricia; Dragano, Nathalia R. V.; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Calzada-Wack, Julia; Kraiger, Markus; Leuchtenberger, Stefanie; Seisenberger, Claudia; Marschall, Susan; Rathkolb, Birgit; Scifo, Enzo; Liu, Ting; Thanabalasingam, Anoja; Sanchez-Vazquez, Raul; Martinez, Paula; Blasco, Maria A.; Savage, Sharon A.; Fuchs, Helmut; Ehninger, Dan; Gailus-Durner, Valerie 分享 收藏
X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes Hasenbein, Tim P.; Hoelzl, Sarah; Smith, Zachary D.; Gerhardinger, Chiara; Gonner, Marion O. C.; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Dragano, Nathalia R. V.; da Silva-Buttkus, Patricia; Garrett, Lillian; Hoelter, Sabine M.; Kraiger, Markus; Oestereicher, Manuela A.; Rathkolb, Birgit; Sanz-Moreno, Adrian; Spielmann, Nadine; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Meissner, Alexander; Engelhardt, Stefan; Rinn, John L.; Andergassen, Daniel 分享 收藏
The eATP/P2x7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation eATP/P2x7R轴驱动量子点纳米颗粒诱导的肺微循环中性粒细胞募集 Li, Chenxi; Liu, Qiongliang; Han, Lianyong; Zhang, Haiyun; Immler, Roland; Rathkolb, Birgit; Secklehner, Judith; de Angelis, Martin Hrabe; Yildirim, Ali oender; Zeuschner, Dagmar; Nicke, Annette; Carlin, Leo M.; Sperandio, Markus; Stoeger, Tobias; Rehberg, Markus 分享 收藏
Examining the liver-pancreas crosstalk reveals a role for the molybdenum cofactor in β-cell regeneration Karampelias, Christos; Batoiu, Bianca; Rathkolb, Birgit; da Silva-Buttkus, Patricia; Bachar-Wikstrom, Etty; Marschall, Susan; Fuchs, Helmut; Gailus-Durner, Valerie; Chu, Lianhe; de Angelis, Martin Hrabe; Andersson, Olov 分享 收藏
Decreased β-cell volume and insulin secretion but preserved glucose tolerance in a growth hormone insensitive pig model Laane, Laeticia; Renner, Simone; Kemter, Elisabeth; Stirm, Michael; Rathkolb, Birgit; Blutke, Andreas; Bidlingmaier, Martin; de Angelis, Martin Hrabe; Wolf, Eckhard; Hinrichs, Arne 分享 收藏
Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ Hoenes, Georg Sebastian; Geist, Daniela; Wenzek, Christina; Pfluger, Paul Thomas; Mueller, Timo Dirk; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Dragano, Natalia; Garrett, Lillian; Hoelter, Sabine Maria; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Fuehrer, Dagmar; Moeller, Lars Christian 分享 收藏
Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT) Riedhammer, Korbinian M.; Nguyen, Thanh-Minh T.; Kosukcu, Can; Calzada-Wack, Julia; Li, Yong; Batzir, Nurit Assia; Saygili, Seha; Wimmers, Vera; Kim, Gwang-Jin; Chrysanthou, Marialena; Bakey, Zeineb; Sofrin-Drucker, Efrat; Kraiger, Markus; Sanz-Moreno, Adrian; Amarie, Oana V.; Rathkolb, Birgit; Klein-Rodewald, Tanja; Garrett, Lillian; Hoelter, Sabine M.; Seisenberger, Claudia; Haug, Stefan; Schlosser, Pascal; Marschall, Susan; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Wuttke, Matthias; de Angelis, Martin Hrabe; Comic, Jasmina; Dogan, Ozlem Akgun; Ozluk, Yasemin; Tasdemir, Mehmet; Agbas, Ayse; Canpolat, Nur; Orenstein, Naama; Caliskan, Salim; Weber, Ruthild G.; Bergmann, Carsten; Jeanpierre, Cecile; Saunier, Sophie; Lim, Tze Y.; Hildebrandt, Friedhelm; Alhaddad, Bader; Basel-Salmon, Lina; Borovitz, Yael; Wu, Kaman; Antony, Dinu; Matschkal, Julia; Schaaf, Christian W.; Renders, Lutz; Schmaderer, Christoph; Rogg, Manuel; Schell, Christoph; Meitinger, Thomas; Heemann, Uwe; Koettgen, Anna; Arnold, Sebastian J.; Ozaltin, Fatih; Schmidts, Miriam; Hoefele, Julia 分享 收藏
Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model Shashikadze, Bachuki; Valla, Libera; Lombardo, Salvo Danilo; Prehn, Cornelia; Haid, Mark; Riols, Fabien; Stoeckl, Jan Bernd; Elkhateib, Radwa; Renner, Simone; Rathkolb, Birgit; Menche, Joerg; de Angelis, Martin Hrabe; Wolf, Eckhard; Kemter, Elisabeth; Froehlich, Thomas 分享 收藏
Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease Calame, Daniel G.; Guo, Tianyu; Wang, Chen; Garrett, Lillian; Jolly, Angad; Dawood, Moez; Kurolap, Alina; Henig, Noa Zunz; Fatih, Jawid M.; Herman, Isabella; Du, Haowei; Mitani, Tadahiro; Becker, Lore; Rathkolb, Birgit; Gerlini, Raffaele; Seisenberger, Claudia; Marschall, Susan; Hunter, Jill, V; Gerard, Amanda; Heidlebaugh, Alexis; Challman, Thomas; Spillmann, Rebecca C.; Jhangiani, Shalini N.; Coban-Akdemir, Zeynep; Lalani, Seema; Liu, Lingxiao; Revah-Politi, Anya; Iglesias, Alejandro; Guzman, Edwin; Baugh, Evan; Boddaert, Nathalie; Rondeau, Sophie; Ormieres, Clothide; Barcia, Giulia; Tan, Queenie K. G.; Thiffault, Sophie Isabelle; Pastinen, Tomi; Sheikh, Kazim; Biliciler, Suur; Mei, Davide; Melani, Federico; Shashi, Vandana; Yaron, Yuval; Steele, Mary; Wakeling, Emma; Ostergaard, Elsebet; Nazaryan-Petersen, Lusine; Millan, Francisca; Santiago-Sim, Teresa; Thevenon, Julien; Bruel, Ange-Line; Thauvin-Robinet, Christel; Popp, Denny; Platzer, Konrad; Gawlinski, Pawel; Wiszniewski, Wojciech; Marafi, Dana; Pehlivan, Davut; Posey, Jennifer E.; Gibbs, Richard A.; Gailus-Durner, Valerie; Guerrini, Renzo; Fuchs, Helmut; de Angelis, Martin Hrabe; Hoelter, Sabine M.; Cheung, Hoi-Hung; Gu, Shen; Lupski, James R. 分享 收藏
Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria Lucienne, Marie; Gerlini, Raffaele; Rathkolb, Birgit; Calzada-Wack, Julia; Forny, Patrick; Wueest, Stephan; Kaech, Andres; Traversi, Florian; Forny, Merima; Burer, Celine; Aguilar-Pimentel, Antonio; Irmler, Martin; Beckers, Johannes; Sauer, Sven; Koelker, Stefan; Dewulf, Joseph P.; Bommer, Guido T.; Hoces, Daniel; Gailus-Durner, Valerie; Fuchs, Helmut; Rozman, Jan; Froese, D. Sean; Baumgartner, Matthias R.; de Angelis, Martin Hrabe 分享 收藏
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Generation and characterization of dickkopf3 mutant mice Barrantes, ID; Montero-Pedrazuela, A; Guadaño-Ferraz, A; Obregon, MJ; de Mena, RM; Gailus-Durner, V; Fuchs, H; Franz, TJ; Kalaydjiev, S; Klempt, M; Hölter, S; Rathkolb, B; Reinhard, C; de Escobar, GM; Bernal, J; Busch, DH; Wurst, W; Wolf, E; Schulz, H; Shtrom, S; Greiner, E; de Angelis, MH; Westphal, H; Niehrs, C 分享 收藏
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice Musiol, Stephanie; Harris, Carla P.; Karlina, Ruth; Gostner, Johanna M.; Rathkolb, Birgit; Schnautz, Benjamin; Schneider, Evelyn; Mair, Lisa; Vergara, Ernesto Elorduy; Flexeder, Claudia; Koletzko, Sibylle; Bauer, Carl-Peter; Schikowski, Tamara; Berdel, Dietrich; von Berg, Andrea; Herberth, Gunda; Rozman, Jan; de Angelis, Martin Hrabe; Standl, Marie; Schmidt-Weber, Carsten B.; Ussar, Siegfried; Alessandrini, Francesca 分享 收藏
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