David J. Thornton - Publications, H-index & Citations

David J. Thornton

University of Manchester

65H指数

250论文数

1.4W被引数

收录论文 95

发表时间

AquIRE reveals the mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs AquIRE揭示了临床诱导的RNA损伤机制以及糖基RNA的保守性和动态性

Nucleic Acids Research

IF13.1

2026-02-27

PREAI

Zhang, Zijian; Kotopanova, Zornitsa Vasileva; Dang, Kexin; Kong, Xiangxu; Simms, Nicole; Yuen, Tin wai; Lam, Lan; Beadle, Lauren Forbes; Hilton, Emma; Qureshi, Taqdees; Coppola, Marianna; Holmes, Callum David; Kan, Kwan Ting; Ashe, Mark; Gallois, Patrick; Ashe, Hilary; Braun, Michael; Saunders, Mark; Sutton, Paul; Thornton, David J.; Knight, John R. P.

Proteoglycofili are glycosaminoglycan-containing fibrillar components released by neutrophils to neutralize bacteria 蛋白多糖丝是中性粒细胞释放的含糖胺聚糖的纤维状组分，用于中和细菌。

Cell Reports

IF6.9

2025-11-13

OAAI

Antonin C. André; Marina V. Barroso; Jurate Skerniskyte; Lorine Debande; Vanessa Paul; Nathan Broussaudier; Ahmad Sabbah; Jules Tritschler; Mélina Siegwald; Caroline Ridley; Isabelle Svahn; Amber D. Bowler; Valérie Demais; Katia Boniface; Stéphane Rigaud; Jean-Yves Tinevez; Philippe J. Sansonetti; Freddy Radtke; Romain R. Vivès; David J. Thornton

Functional divergence of MdpS and MdpS2 reveals mucin-targeting strategies in Streptococcus oralis MdpS和MdpS2的功能分化揭示了链球菌属唾液链球菌靶向黏蛋白的策略

Journal of Oral Microbiology

IF5.5

2025-10-26

OAAI

Fredrik Leo; Jonas Nilsson; Liisa Arike; Sahana Kumar; Emma Hilton; Rolf Lood; David J. Thornton; Gregg A. Duncan; Gunnel Svensäter; Claes Wickström

Sputum rheology critical stress is associated with non-cystic fibrosis bronchiectasis severity

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Tavernier, Gael; Wood, Marion; Thornton, David; Fowler, Stephen; Lord, Robert; Pantin, Thomas

The Tmem16a chloride channel is required for mucin maturation after secretion from goblet-like cells in the Xenopus tropicalis tadpole skin

SCIENTIFIC REPORTS

IF3.9

2024-10-26

OAAI

Dubaissi, Eamon; Hilton, Emma N.; Lilley, Sarah; Collins, Richard; Holt, Charlotte; March, Peter; Danahay, Henry; Gosling, Martin; Grencis, Richard K.; Roberts, Ian S.; Thornton, David J.

Sex drives colonic mucin sialylation in wild mice

SCIENTIFIC REPORTS

IF3.9

2024-03-23

OAAI

Bennett, Alexander R.; Mair, Iris; Muir, Andrew; Smith, Hannah; Logunova, Larisa; Wolfenden, Andrew; Fenn, Jonathan; Lowe, Ann E.; Bradley, Janette E.; Else, Kathryn J.; Thornton, David J.

Sputum rheology is associated with asthma control

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

PREAI

Tavernier, Gael; Qureshi, Taqdees; Zurel, Furkan; Holmes, Leanne; Elsey, Lynn; Thornton, David; Fowler, Stephen; Pantin, Thomas

Sputum rheology measurements in chronic respiratory diseases are similar across specialist centres

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

PREAI

Tavernier, Gael; Qureshi, Taqdees; Volpato, Mathilde; Vachier, Isabelle; Wood, Marion; Zurel, Furkan; Thornton, David; De Saint Vincent, Matthieu Robert; Patarin, Jeremy; Lord, Robert; Fowler, Stephen; Charriot, Jeremy

Mucin networks: Dynamic structural assemblies controlling mucus function

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-04-01

OAAI

Fass, Deborah; Thornton, David J.

Mucus aberrant properties in CF: Insights from cells and animal models CF中的粘液异常特性: 来自细胞和动物模型的见解

JOURNAL OF CYSTIC FIBROSIS

IF6

2023-03-01

OAAI

Ehre, Camille; Hansson, Gunnar C.; Thornton, David J.; Ostedgaard, Lynda S.

High-fat diet-induced resistance to helminth infection via alternative induction of type 2 immunity

MUCOSAL IMMUNOLOGY

IF7.6

2023-02-01

OAAI

Funjika, Evelyn; Colombo, Stefano A. P.; Hayes, Kelly S.; Tozer, Mary J.; Tyrrell, Katrina A.; Cai, Shanshan; Faniyi, Aduragbemi A.; Shears, Rebecca K.; Dooley, Megan; Alshammari, Yasmine; Alhazmi, Wafaa; Assas, Mushref; Almilaibary, Abdullah; Jackson-Jones, Lucy H.; Thornton, David J.; Worthington, John J.; Grencis, Richard K.

The lipophilic cyclic peptide cyclosporin A induces aggregation of gel-forming mucins

SCIENTIFIC REPORTS

IF3.9

2022-04-13

OAAI

Kishimoto, Hisanao; Ridley, Caroline; Thornton, David J.

Assembly and organization of the N-terminal region of mucin MUC5AC: Indications for structural and functional distinction from MUC5B

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-09-21

OAAI

Carpenter, Jerome; Wang, Yang; Gupta, Richa; Li, Yuanli; Haridass, Prashamsha; Subramani, Durai B.; Reidel, Boris; Morton, Lisa; Ridley, Caroline; O'Neal, Wanda K.; Buisine, Marie-Pierre; Ehre, Camille; Thornton, David J.; Kesimer, Mehmet

Mucus

CURRENT BIOLOGY

IF7.5

2021-08-01

OAAI

McShane, Abigail; Bath, Jade; Jaramillo, Ana M.; Ridley, Caroline; Walsh, Agnes A.; Evans, Christopher M.; Thornton, David J.; Ribbeck, Katharina

Disulfide disruption reverses mucus dysfunction in allergic airway disease

NATURE COMMUNICATIONS

IF15.7

2021-01-11

OAAI

Morgan, Leslie E.; Jaramillo, Ana M.; Shenoy, Siddharth K.; Raclawska, Dorota; Emezienna, Nkechinyere A.; Richardson, Vanessa L.; Hara, Naoko; Harder, Anna Q.; NeeDell, James C.; Hennessy, Corinne E.; El-Batal, Hassan M.; Magin, Chelsea M.; Villalon, Diane E. Grove; Duncan, Gregg; Hanes, Justin S.; Suk, Jung Soo; Thornton, David J.; Holguin, Fernando; Janssen, William J.; Thelin, William R.; Evans, Christopher M.

Using Lean-Facilitation to Improve Quality of Hepatitis C Testing in Primary Care

JOURNAL OF GENERAL INTERNAL MEDICINE

IF4.2

2020-09-15

OAAI

Yakovchenko, Vera; DeSotto, Kristine; Drainoni, Mari-Lynn; Lukesh, William; Miller, Donald R.; Park, Angela; Shao, Qing; Thornton, David J.; Gifford, Allen L.

Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis 非囊性纤维化支气管扩张中的气道粘液高浓度

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2020-03-15

PREAI

Ramsey, Kathryn A.; Chen, Alice C. H.; Radicioni, Giorgia; Lourie, Rohan; Martin, Megan; Broomfield, Amy; Sheng, Yong H.; Hasnain, Sumaira Z.; Radford-Smith, Graham; Simms, Lisa A.; Burr, Lucy; Thornton, David J.; Bowler, Simon D.; Livengood, Stephanie; Ceppe, Agathe; Knowles, Michael R.; Noone, Peadar G., Sr.; Donaldson, Scott H.; Hill, David B.; Ehre, Camille; Button, Brian; Alexis, Neil E.; Kesimer, Mehmet; Boucher, Richard C.; McGuckin, Michael A.

The MUC5B mucin polymer is dominated by repeating structural motifs and its topology is regulated by calcium and pH

SCIENTIFIC REPORTS

IF3.9

2019-11-22

OAAI

Hughes, Gareth W.; Ridley, Caroline; Collins, Richard; Roseman, Alan; Ford, Robert; Thornton, David J.

Trickle infection and immunity to Trichuris muris

PLOS PATHOGENS

IF4.9

2019-11-15

OAAI

Glover, Maya; Colombo, Stefano A. P.; Thornton, David J.; Grencis, Richard K.

The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-11-01

OAAI

Ridley, Caroline; Lockhart-Cairns, Michael P.; Collins, Richard F.; Jowitt, Thomas A.; Subramani, Durai B.; Kesimer, Mehmet; Baldock, Clair; Thornton, David J.

研究方向