Laura Rubio‐Pérez - Publications, H-index & Citations

Laura Rubio‐Pérez

hospital universitario2 de octubre

15H指数

57论文数

649被引数

收录论文 17

发表时间

mRNA-engineered T lymphocytes secreting bispecific T cell engagers with therapeutic potential in solid tumors mRNA工程化T淋巴细胞分泌具有实体瘤治疗潜力的双特异性T细胞接合物

Frontiers in Immunology

IF5.9

2025-11-18

OAAI

Ivana Zagorac; Ángel Ramírez-Fernández†; Antonio Tapia-Galisteo; Laura Rubio-Pérez; Marina Gómez-Rosel; Montserrat Grau; José Luis Rodríguez-Peralto; Luis Álvarez-Vallina; Belén Blanco

Simultaneous secretion of a PD-L1 x 4-1BB bispecific antibody improves antileukemic efficacy of STAb-T cells secreting a CD19-specific T-cell engager 同时分泌PD-L1 x 4-1BB双特异性抗体的行为，增强了分泌CD19特异性T细胞结合剂的STAb-T细胞的抗白血病疗效。

OncoImmunology

IF6.3

2025-10-26

OAAI

Marina Gómez-Rosel; Laura Rubio-Pérez; Ivana Zagorac; Carmen Domínguez-Alonso; Laura Díez-Alonso; Oana Hangiu; Rocío Navarro; Raúl Torres-Ruíz; Sandra Rodríguez-Perales; Francisco J. Blanco; Marta Compte; Luis Álvarez-Vallina; Belén Blanco

Effective cancer immunotherapy combining mRNA-encoded bispecific antibodies that induce polyclonal T cell engagement and PD-L1-dependent 4-1BB costimulation

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-01-06

OAAI

Hangiu, Oana; Navarro, Rocio; Frago, Susana; Rubio-Perez, Laura; Tapia-Galisteo, Antonio; Diez-Alonso, Laura; Gomez-Rosel, Marina; Silva-Pilipich, Noelia; Vanrell, Lucia; Smerdou, Cristian; Howard, Kenneth A.; Sanz, Laura; alvarez-Vallina, Luis; Compte, Marta

Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity

ANTIBODIES

IF2.7

2024-04-24

OAAI

Rubio-Perez, Laura; Frago, Susana; Compte, Marta; Navarro, Rocio; Harwood, Seandean L.; Lazaro-Gorines, Rodrigo; Gomez-Rosel, Marina; Hangiu, Oana; Silva-Pilipich, Noelia; Vanrell, Lucia; Smerdou, Cristian; Alvarez-Vallina, Luis

Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo 分泌抗BCMA T细胞衔接剂的工程化T细胞控制多发性骨髓瘤并促进体内免疫记忆

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-02-14

PREAI

Diez-Alonso, Laura; Falgas, Aida; Arroyo-Rodenas, Javier; Romencin, Paola A.; Martinez, Alba; Gomez-Rosel, Marina; Blanco, Belen; Jimenez-Reinoso, Anais; Mayado, Andrea; Perez-Pons, Alba; Aguilar-Sopena, Oscar; Ramirez-Fernandez, Angel; Segura-Tudela, Alejandro; Perez-Amill, Lorena; Tapia-Galisteo, Antonio; Dominguez-Alonso, Carmen; Rubio-Perez, Laura; Jara, Maria; Sole, Francesc; Hangiu, Oana; Almagro, Laura; Albitre, Angela; Penela, Petronila; Sanz, Laura; Anguita, Eduardo; Valeri, Antonio; Garcia-Ortiz, Almudena; Rio, Paula; Juan, Manel; Martinez-Lopez, Joaquin; Roda-Navarro, Pedro; Martin-Antonio, Beatriz; Orfao, Alberto; Menendez, Pablo; Bueno, Clara; alvarez-Vallina, Luis

Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2 双特异性中和抗体介导的树突状细胞介导的交叉引发可增强细胞毒性T细胞反应并保护小鼠免受SARS-CoV-2

ADVANCED SCIENCE

IF14.1

2023-10-20

OAAI

Lazaro-Gorines, Rodrigo; Perez, Patricia; Heras-Murillo, Ignacio; Adan-Barrientos, Irene; Albericio, Guillermo; Astorgano, David; Flores, Sara; Luczkowiak, Joanna; Labiod, Nuria; Harwood, Seandean L.; Segura-Tudela, Alejandro; Rubio-Perez, Laura; Nugraha, Yudhi; Shang, Xiaoran; Li, Yuxing; Alfonso, Carlos; Adipietro, Kaylin A.; Abeyawardhane, Dinendra L.; Navarro, Rocio; Compte, Marta; Yu, Wenbo; Mackerell, Alexander D.; Sanz, Laura; Weber, David J.; Blanco, Francisco J.; Esteban, Mariano; Pozharski, Edwin; Godoy-Ruiz, Raquel; Munoz, Ines G.; Delgado, Rafael; Sancho, David; Garcia-Arriaza, Juan; Alvarez-Vallina, Luis

A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response

ONCOIMMUNOLOGY

IF6.3

2023-04-24

OAAI

Rubio-Perez, Laura; Lazaro-Gorines, Rodrigo; Harwood, Seandean L.; Compte, Marta; Navarro, Rocio; Tapia-Galisteo, Antonio; Bonet, Jaume; Blanco, Belen; Lykkemark, Simon; Ramirez-Fernandez, Angel; Ferreras-Gutierrez, Mariola; Dominguez-Alonso, Carmen; Diez-Alonso, Laura; Segura-Tudela, Alejandro; Hangiu, Oana; Erce-Llamazares, Ainhoa; Blanco, Francisco J.; Santos, Cruz; Rodriguez-Peralto, Jose L.; Sanz, Laura; Alvarez-Vallina, Luis

A well-defined NHC-Ir(III) catalyst for the silylation of aromatic C-H bonds: substrate survey and mechanistic insights

CHEMICAL SCIENCE

IF7.4

2017-01-01

OAAI

Rubio-Perez, Laura; Iglesias, Manuel; Munarriz, Julen; Polo, Victor; Passarelli, Vincenzo; Perez-Torrente, Jesus J.; Oro, Luis A.

Efficient Rhodium-Catalyzed Multicomponent Reaction for the Synthesis of Novel Propargylamines

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2015-10-22

OAAI

Rubio-Perez, Laura; Iglesias, Manuel; Munarriz, Julen; Polo, Victor; Perez-Torrente, Jesus J.; Oro, Luis A.

A bimetallic iridium(II) catalyst: [{Ir(IDipp)(H)}2][BF4]2 (IDipp=1,3-bis(2,6-diisopropylphenylimidazol-2-ylidene))

CHEMICAL COMMUNICATIONS

IF4.2

2015-01-01

OAAI

Rubio-Perez, Laura; Iglesias, Manuel; Munarriz, Julen; Polo, Victor; Miguel, Pablo J. Sanz; Perez-Torrente, Jesus J.; Oro, Luis A.

Rhodium(I)-N-Heterocyclic Carbene Catalyst for Selective Coupling of N-Vinylpyrazoles with Alkynes via C-H Activation 铑 (I)-N-杂环卡宾催化剂通过c-h活化选择性偶联N-乙烯基吡唑与炔烃

ACS CATALYSIS

IF13.1

2014-10-30

OAAI

Azpiroz, Ramon; Rubio-Perez, Laura; Di Giuseppe, Andrea; Passarelli, Vincenzo; Lahoz, Fernando J.; Castarlenas, Ricardo; Perez-Torrente, Jesus J.; Oro, Luis A.

Selective C-H Bond Functionalization of 2-(2-Thienyl)-pyridine by a Rhodium N-Heterocyclic Carbene Catalyst 铑N-杂环卡宾催化剂对2-(2-噻吩基)-吡啶的选择性c-h键官能化

CHEMCATCHEM

IF3.9

2014-09-12

OAAI

Rubio-Perez, Laura; Iglesias, Manuel; Castarlenas, Ricardo; Polo, Victor; Perez-Torrente, Jesus J.; Oro, Luis A.

gem-Selective Cross-Dimerization and Cross-Trimerization of Alkynes with Silylacetylenes Promoted by a Rhodium-Pyridine-N-Heterocyclic Carbene Catalyst

CHEMCATCHEM

IF3.9

2014-07-25

OAAI

Azpiroz, Ramon; Rubio-Perez, Laura; Castarlenas, Ricardo; Perez-Torrente, Jesus J.; Oro, Luis A.

Diastereo- and enantioselective reductive amination of cycloaliphatic ketones by preformed chiral palladium complexes

CATALYSIS SCIENCE & TECHNOLOGY

IF4.2

2014-01-01

PREAI

Cabrera, Armando; Sharma, Pankaj; Javier Perez-Flores, F.; Velasco, Luis; Luis Arias, J.; Rubio-Perez, Laura

Pyridine-Enhanced Head-to-Tail Dimerization of Terminal Alkynes by a Rhodium-N-Heterocyclic-Carbene Catalyst 吡啶通过铑-N-杂环-卡宾催化剂增强末端炔烃的头-尾二聚

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2013-09-23

OAAI

Rubio-Perez, Laura; Azpiroz, Ramon; Di Giuseppe, Andrea; Polo, Victor; Castarlenas, Ricardo; Perez-Torrente, Jesus J.; Oro, Luis A.

Competitive intermolecular cyclotrimerization and cyclocarbonylation products in Pauson-Khand reaction

CATALYSIS COMMUNICATIONS

IF4.3

2009-02-01

PREAI

Luis Arias, Jose; Cabrera, Armando; Sharma, Pankaj; Rosas, Noe; Toscano, Alfredo; Elvira Martinez, Elideth; Rubio-Perez, Laura

Stable Preformed Chiral Palladium Catalysts for the One-Pot Asymmetric Reductive Amination of Ketones

ORGANIC LETTERS

IF5

2008-12-18

108

PREAI

Rubio-Perez, Laura; Perez-Flores, F. Javier; Sharma, Pankaj; Velasco, Luis; Cabrera, Armando

研究方向