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许建和 封面图

许建和 (Jian‐He Xu)

east china university of science and technology

31H指数
166论文数
2.6K被引数
收录论文 286
发表时间
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Loop-Centric Engineering of Terminal Deoxynucleotidyl Transferase for Enhanced Catalysis of 3'-Modified Nucleotides末端脱氧核苷酸转移酶的环中心工程改造以增强3'-修饰核苷酸的催化活性
errBiotechnology and Bioengineering
IF3.6
err2026-10-01
err0
PREAI
errKun Shi; An-Na Li; Jian-He Xu; Hui-Lei Yu
err分享
err收藏
An Engineered β-Aminopeptidase With Better Product Selectivity for L-Carnosine Production一种用于L-肌肽生产且具有更好产物选择性的工程β-氨肽酶
errChemBioChem
IF2.8
err2026-09-21
err0
PREAI
errBi-Han Guan; Wu-Tong Yin; Chen Zhao; Jiang Pan; Jian-He Xu
err分享
err收藏
A Sustainable and Tunable Methanol-Driven Sesquiterpene-Biomanufacturing Platform Using Engineered Komagataella phaffii利用工程化Komagataella phaffii构建的可持续且可调的甲醇驱动倍半萜生物制造平台
errProcess Biochemistry
IF4
err2026-09-17
err0
PREAI
errNuo Zhang; Zheng-Yu Huang; Xing-Kai Li; Gao-Wei Zheng; Chun-Xiu Li; Jian-He Xu
err分享
err收藏
Efficient Synthesis of Ergothioneine in Escherichia coli Through Identification of Bacterial-Type Egt1 and Self-Assemble of Pathway Enzymes通过鉴定细菌型Egt1和途径酶的自组装高效合成大肠杆菌中的 Ergothioneine
errBiotechnology and Bioengineering
IF3.6
err2026-05-17
err0
PREAI
errXin-Yi Chen; Shuai Yan; Hang-Cheng Li; Hai-Ping Liu; Hui-Lei Yu; Jian-He Xu; Zhi-Jun Zhang
err分享
err收藏
Engineering P450 Peroxygenase Overoxidation Promiscuity Enables Concise and High-Yielding Biocatalytic Synthesis of d-Amino Acids from Fatty Acids通过工程改造P450过氧化物酶的过氧化反应广谱性，实现了从脂肪酸出发简洁高效生物催化合成D-氨基酸
errACS Catalysis
IF13.1
err2026-04-30
err0
PREAI
errXing Yu; Peng Deng; Sheng Gu; Bu-Bing Zeng; Hui-Lei Yu; Jian-He Xu; Zhi-Jun Zhang
err分享
err收藏
Characterization and Engineering of an Aminopeptidase for Enhancing L-Carnosine Synthesis and Decreasing Dipeptide Hydrolysis氨肽酶的表征与改造：用于增强L-肌肽合成并减少二肽水解
errProcess Biochemistry
IF4
err2026-04-20
err0
PREAI
errBi-Han Guan; Wu-Tong Yin; Jiang Pan; Jian-He Xu
err分享
err收藏
Dual Flow Reactor Approach for the Chemoenzymatic Production of Chenodeoxycholic Acid; a Precursor to Ursodeoxycholic Acid双流反应器法用于化学酶法生产鹅去氧胆酸；其为熊去氧胆酸的前体
errJournal of Agricultural and Food Chemistry
IF6.2
err2026-03-31
err0
PREAI
errBing-Yi Yang; Ya-Jing Liu; Jiang Pan; Gao-Wei Zheng; Jian-He Xu; Chun-Xiu Li
err分享
err收藏
Integration of pathway balance and protein fusion enables de novo biosynthesis of (+)-bicyclogermacrene in Escherichia coli整合通路平衡与蛋白质融合技术，实现了在*Escherichia coli*中从头生物合成(+)-双环柠檬烯。
errBioresources and Bioprocessing
IF5.1
err2026-02-28
err0
errOAAI
errChen-Yi Sun; Wen-Liang Xie; Zheng-Yu Huang; Chun-Xiu Li; Jian-He Xu
err分享
err收藏
Reconstruction of the Early Stage Paclitaxel Biosynthesis Pathway in Escherichia coli by Integrating Enzyme and Metabolic Engineering Approaches
errACS Sustainable Chemistry and Engineering
IF7.3
err2026-01-30
err0
PREAI
errWen-Liang Xie; Chen-Yi Sun; Chun-Xiu Li; Gao-Wei Zheng; Jian-He Xu
err分享
err收藏
Metabolic engineering of Yarrowia lipolytica targeting bottlenecks to boost D-Pantothenic acid biosynthesis溶脂耶氏酵母的代谢工程靶向瓶颈以促进D-泛酸的生物合成
errBioresources and Bioprocessing
IF5.1
err2026-01-27
err0
errOAAI
errXing-Kai Li; Nuo Zhang; Hai-Peng Li; Zheng-Yu Huang; Gao-Yue Niu; Chen-Yi Sun; Jian-He Xu
err分享
err收藏
Designing an oxidase toolbox for site-directed oxidation of taxanes为紫杉烷的位点特异性氧化设计氧化酶工具箱
errNature Communications
IF15.7
err2025-12-17
err0
errOAAI
errMingyuan Lai; Yu Weng; Jian Wei; Xin-Yi Lu; Zhengyu Huang; Hangcheng Li; Longhao Huang; Zhijun Zhang; Lili Zhu; Jian-He Xu; Ran Hong; Hui-Lei Yu
err分享
err收藏
Dihydroxy Terpene Synthase: Spatiotemporally Precise Manipulation of Water-Mediated Dihydroxylation via Stepwise Quenching of Carbocations二羟基松烯合酶：通过分步淬灭碳正离子实现时空精确的水介导二羟基化操控
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-11-01
err0
PREAI
errHuang, Zheng-Yu; Xu, Kangwei; Li, Wen-Li; Li, Chun-Xiu; Pan, Jiang; Wu, Ruibo; Xu, Jian-He
err分享
err收藏
Engineering Escherichia coli for High-Yield Protoporphyrin IX Biosynthesis via Cytotoxicity Mitigation and Pathway Optimization通过降低细胞毒性及路径优化工程改造大肠杆菌，实现高产量原卟啉IX的生物合成
errACS Synthetic Biology
IF3.9
err2025-10-27
err0
PREAI
errPeng Sun; Lin-Lin Qian; Wen-Liang Xie; Yao Jiang; Chun-Xiu Li; Jiang Pan; Jian-He Xu
err分享
err收藏
Engineering an imine reductase for enhanced activity and reduced substrate inhibition: Asymmetric synthesis of chiral 2-aryl pyrrolidines工程化改造亚胺还原酶以提高活性并降低底物抑制：手性2-芳基吡咯烷的不对称合成
errChinese Journal of Catalysis
IF17.7
err2025-10-27
err0
PREAI
errXin-Ru Chen; Tian Jin; Chi Zhang; Zhen-Yu Zhu; Xin-Yuan Shen; Qi Chen; Jing Wang; Jian-He Xu; Gao-Wei Zheng
err分享
err收藏
Flipping of a Non-productive Substrate Binding Conformation Facilitates Hydroxynitrile Lyase Catalyzed Hydrocyanation非活性底物结合构象的翻转促进了羟基腈裂解酶催化的氰化反应
errAngewandte Chemie International Edition
IF16.9
err2025-10-24
err0
PREAI
errDr. Yu-Cong Zheng; Yong Mao; Dr. Qiang Geng; Dr. Fu-Long Li; Prof. Dr. Xu-Dong Kong; Dr. Yi-Ke Qi; Lin Zhang; Prof. Dr. Qi Chen; Prof. Dr. Zhi-Jun Zhang; Prof. Dr. Ran Hong; Prof. Dr. Yi-Lei Zhao; Prof. Dr. Hui-Lei Yu; Prof. Dr. Jian-He Xu
err分享
err收藏
Proximal-to-distal molecular engineering of a halide methyltransferase for green synthesis of S-adenosyl-ethionine卤化物甲基转移酶从近端到远端的分子工程改造，用于S-腺苷高半胱氨酸的绿色合成
errMolecular Catalysis
IF4.9
err2025-10-17
err0
PREAI
errShi-Yu Zhang; Jun-Yi Yang; Yang Yan; Li-Xin Kang; Ai-Tao Li; Jian-He Xu; Gao-Wei Zheng; Qi Chen
err分享
err收藏
Development of an in vitro multi-enzyme system for efficient one-pot biosynthesis of sorbitol from fructose-6-phosphate以果糖-6-磷酸为原料高效一锅法生物合成山梨醇的体外多酶体系开发
errBioresources and Bioprocessing
IF5.1
err2025-09-26
err0
errOAAI
errKai Shen; Chao-Nan Zhu; Jian-He Xu; Gao-Wei Zheng; Qi Chen
err分享
err收藏
ADP-ribose is a competitive inhibitor of methanol dehydrogenases from Bacillus methanolicusADP-核糖是Bacillus methanolicus来源的甲醇脱氢酶的竞争性抑制剂。
errJournal of Biological Chemistry
IF3.9
err2025-08-14
err0
PREAI
errBao-Di Ma; Jia-Yi Li; Jian-He Xu; Tao Yu; Xu-Dong Kong
err分享
err收藏
A Molecular Staircase Built from Hydrazide-Linked Pyridines as an Artificial Proton Channel一种由肼基连接的吡啶构建的分子楼梯作为人工质子通道
errAngewandte Chemie International Edition
IF0
err2025-07-29
err0
PREAI
errJianhe Xu; Yanbin Chen; Jianru Wang; Dr. Wenju Chang; Prof. Dr. Jie Shen; Prof. Dr. Huaqiang Zeng
err分享
err收藏
Hinge loop reconstruction facilitates hydride transfer in Baeyer-Villiger monooxygenases铰链环重构促进Baeyer-Villiger单加氧酶中的氢化物转移
errChem Catalysis
IF11.6
err2025-04-25
err0
PREAI
errQ. Geng; C.D. Zhou; Y.C. Zheng; F. Liu; Q. Chen; Z.J. Zhang; X.D. Kong; Z.K. Zhao; J.H. Xu; H.L. Yu
err分享
err收藏

研究方向

新酶元件设计改造及构效机制多酶级联与合成生物系统构建生物催化工程研究与工业示范
合作学者
合作期刊
刘
刘艳 (Yan Liu)
H 指数: 118 · 论文数: 3.7K
王慧 封面图
王慧 (Hui Wang)
H 指数: 113 · 论文数: 2.3K
U
Uwe T. Bornscheuer
H 指数: 95 · 论文数: 892
N
Nicholas J. Turner
H 指数: 89 · 论文数: 742
陈奇 封面图
陈奇 (Qi Chen)
H 指数: 86 · 论文数: 660
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