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A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy Lafayette, Richard; Barbour, Sean J.; Brenner, Robert M.; Campbell, Kirk N.; Doan, Tom; Eren, Necmi; Floege, Jurgen; Jha, Vivekanand; Kim, Beom Seok; Liew, Adrian; Maes, Bart; Pal, Atanu; Pecoits-Filho, Roberto; Phoon, Richard K. S.; Rizk, Dana V.; Suzuki, Hitoshi; Tesar, Vladimir; Trimarchi, Hernan; Wei, Xuelian; Zhang, Hong; Barratt, Jonathan 分享 收藏
A mechanistic biopsy study of the effect of iptacopan on immunopathology in patients with IgA nephropathy (IgAN) iptacopan对IgA肾病（IgAN）患者免疫病理学影响的机制性活检研究 Rizk, Dana; Maes, Bart; Zhang, Hong; Kretzler, Matthias; Eitner, Frank; Abner, Clint; Valentin, Marie-Anne; Vipin, N.; Di Tata, Maria Fernanda; Barratt, Jonathan 分享 收藏
ORIGIN 2b: changes in Gd-IgA1 and eGFR after discontinuation of atacicept treatment in IgA nephropathy ORIGIN 2b：在IgA肾病中停止阿他西普治疗后的Gd-IgA1和eGFR变化 Barratt, Jonathan; Barbour, Sean; Brenner, Robert; Eren, Necmi; Floege, Jurgen; Jha, Vivekanand; Kim, Sung Gyun; Maes, Bart; Phoon, Richard; Singh, Harmeet; Tesar, Vladimir; Lafayette, Richard 分享 收藏
Effect of iptacopan discontinuation on proteinuria and complement biomarkers in patients with immunoglobulin A nephropathy (IgAN): a post hoc analysis from a Phase II trial iptacopan停用对免疫球蛋白A肾病（IgAN）患者蛋白尿和补体生物标志物的影响：一项来自II期试验的事后分析 Barratt, Jonathan; Rizk, Dana; Zhang, Hong; Maes, Bart; Kashihara, Naoki; Rovin, Brad; Trimarchi, Hernan; Kollins, Dmitrij; Desai, Manasi; Papachristofi, Olympia; Koukouli, Evanthia; Perkovic, Vlado 分享 收藏
Origin 3 study design: a global, randomized, controlled, Phase 3 study of atacicept in IgA nephropathy Origin 3研究设计：一项关于atacicept在IgA肾病中的全球性、随机化、对照性III期研究 Lafayette, Richard; Maes, Bart; Brenner, Robert; Khawaja, Zeeshan; Floege, Jurgen; Jha, Vivekanand; Tesar, Vladimir; Zhang, Hong; Barbour, Sean; Suzuki, Hitoshi; Trimarchi, Hernan; Barratt, Jonathan 分享 收藏
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A phase 2b, randomized, double-blind, placebo-controlled, clinical trial of atacicept for treatment of IgA nephropathy Lafayette, Richard; Barbour, Sean; Israni, Rubeen; Wei, Xuelian; Eren, Necmi; Floege, Juergen; Jha, Vivekanand; Kim, Sung Gyun; Maes, Bart; Phoon, Richard K. S.; Singh, Harmeet; Tesar, Vladimir; Lin, Celia J. F.; Barratt, Jonathan 分享 收藏
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Results of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy 一项随机双盲安慰剂对照2期研究的结果表明，iptacopan可作为IgA肾病的替代补体途径抑制剂 Zhang, Hong; Rizk, Dana, V; Perkovic, Vlado; Maes, Bart; Kashihara, Naoki; Rovin, Brad; Trimarchi, Hernan; Sprangers, Ben; Meier, Matthias; Kollins, Dmitrij; Papachristofi, Olympia; Milojevic, Julie; Junge, Guido; Nidamarthy, Prasanna Kumar; Charney, Alan; Barratt, Jonathan 分享 收藏
Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial Rovin, Brad H.; Barratt, Jonathan; Heerspink, Hiddo J. L.; Alpers, Charles E.; Bieler, Stewart; Chae, Dong-Wan; Diva, Ulysses A.; Floege, Juergen; Gesualdo, Loreto; Inrig, Jula K.; Kohan, Donald E.; Komers, Radko; Kooienga, Laura Ann; Lafayette, Richard; Maes, Bart; Malecki, Robert; Mercer, Alex; Noronha, Irene L.; Oh, Se Won; Peh, Chen Au; Praga, Manuel; Preciado, Priscila; Radhakrishnan, Jai; Rheault, Michelle N.; Rote, William E.; Tang, Sydney C. W.; Tesar, Vladimir; Trachtman, Howard; Trimarchi, Hernan; Tumlin, James A.; Wong, Muh Geot; Perkovic, Vlado 分享 收藏
A meta-analysis of GFR slope as a surrogate endpoint for kidney failure GFR斜率作为肾衰竭替代终点的荟萃分析 Inker, Lesley; Collier, Willem; Greene, Tom; Miao, Shiyuan; Chaudhari, Juhi; Appel, Gerald; Badve, Sunil; Caravaca-Fontan, Fernando; Del Vecchio, Lucia; Floege, Juergen; Goicoechea, Marian; Haaland, Benjamin; Herrington, William; Imai, Enyu; Jafar, Tazeen H.; Lewis, Julia; Li, Philip K. T.; Maes, Bart; Neuen, Brendon; Perrone, Ronald; Remuzzi, Giuseppe; Schena, Francesco; Wanner, Christoph; Wetzels, Jack F. M.; Woodward, Mark; Heerspink, Hiddo J. L. 分享 收藏
Targeting the Alternative Complement Pathway With Iptacopan to Treat IgA Nephropathy: Design and Rationale of the APPLAUSE-IgAN Study 以Iptacopan靶向替代补体途径治疗IgA肾病: apprause-IgAN研究的设计和原理 Rizk, Dana, V; Rovin, Brad H.; Zhang, Hong; Kashihara, Naoki; Maes, Bart; Trimarchi, Hernan; Perkovic, Vlado; Meier, Matthias; Kollins, Dmitrij; Papachristofi, Olympia; Charney, Alan; Barratt, Jonathan 分享 收藏
Evaluation of Variation in the Performance of GFR Slope as a Surrogate End Point for Kidney Failure in Clinical Trials that Differ by Severity of CKD Collier, Willem; Inker, Lesley A.; Haaland, Benjamin; Appel, Gerald B.; Badve, Sunil V.; Caravaca-Fontan, Fernando; Chalmers, John; Floege, Jurgen; Goicoechea, Marian; Imai, Enyu; Jafar, Tazeen H.; Lewis, Julia B.; Li, Philip K. T.; Locatelli, Francesco; Maes, Bart D.; Neuen, Brendon L.; Perrone, Ronald D.; Remuzzi, Giuseppe; Schena, Francesco P.; Wanner, Christoph; Heerspink, Hiddo J. L.; Greene, Tom 分享 收藏
Clinicopathological characteristics and disease chronicity in native kidney biopsies in Flanders Deleersnijder, Dries; Laurens, Wim; De Meester, Johan; Cleenders, Evert; Dendooven, Amelie; Lerut, Evelyne; De Vriese, An S.; Dejagere, Tom; Helbert, Mark; Hellemans, Rachel; Koshy, Priyanka; Maes, Bart; Pipeleers, Lissa; Van Craenenbroeck, Amaryllis H.; Van Laecke, Steven; Vande Walle, Johan; Couttenye, Marie M.; Meeus, Gert; Sprangers, Ben 分享 收藏
Epidemiology of native kidney disease in Flanders: results from the FCGG kidney biopsy registry Laurens, Wim; Deleersnijder, Dries; Dendooven, Amelie; Lerut, Evelyne; De Vriese, An S.; Dejagere, Tom; Helbert, Mark; Hellemans, Rachel; Koshy, Priyanka; Maes, Bart; Pipeleers, Lissa; Van Craenenbroeck, Amaryllis H.; Van Laecke, Steven; Vande Walle, Johan; Coutteneye, Marie M.; De Meester, Johan; Sprangers, Ben 分享 收藏
Association of Treatment Effects on Early Change in Urine Protein and Treatment Effects on GFR Slope in IgA Nephropathy: An Individual Participant Meta-analysis IgA肾病早期尿蛋白变化与GFR斜率治疗效果的关系: 一项个体参与者的Meta分析 Inker, Lesley A.; Heerspink, Hiddo J. L.; Tighiouart, Hocine; Chaudhari, Juhi; Miao, Shiyuan; Diva, Ulysses; Mercer, Alex; Appel, Gerald B.; Donadio, James, V; Floege, Jurgen; Li, Philip K. T.; Maes, Bart D.; Locatelli, Francesco; Praga, Manuel; Schena, Francesco P.; Levey, Andrew S.; Greene, Tom 分享 收藏
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