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ID1 Facilitates the Growth and Metastasis of Non-Small Cell Lung Cancer in Response to Nicotinic Acetylcholine Receptor and Epidermal Growth Factor Receptor Signaling Pillai, Smitha; Rizwani, Wasia; Li, Xueli; Rawal, Bhupendra; Nair, Sajitha; Schell, Michael J.; Bepler, Gerold; Haura, Eric; Coppola, Domenico; Chellappan, Srikumar 分享 收藏
ATR inhibition overcomes platinum tolerance associated with ERCC1-and p53-deficiency by inducing replication catastrophe Heyza, Joshua R.; Ekinci, Elmira; Lindquist, Jacob; Lei, Wen; Yunker, Christopher; Vinothkumar, Vilvanathan; Rowbotham, Rachelle; Polin, Lisa; Snider, Natalie G.; Van Buren, Eric; Watza, Donovan; Back, Jessica B.; Chen, Wei; Mamdani, Hirva; Schwartz, Ann G.; Turchi, John J.; Bepler, Gerold; Patrick, Steve M. 分享 收藏
A Randomized, Open-Label Phase II Study Evaluating Emibetuzumab Plus Erlotinib and Emibetuzumab Monotherapy in MET Immunohistochemistry Positive NSCLC Patients with Acquired Resistance to Erlotinib 一项随机，开放标签的II期研究，评估了Emibetuzumab联合厄洛替尼和Emibetuzumab单药治疗对厄洛替尼获得性耐药的MET免疫组织化学阳性NSCLC患者 Camidge, D. Ross; Moran, Teresa; Demedts, Ingel; Grosch, Heidrun; Mileham, Kathryn; Molina, Julian; Juan-Vidal, Oscar; Bepler, Gerold; Goldman, Jonathan W.; Park, Keunchil; Wallin, Johan; Wijayawardana, Sameera R.; Wang, Xuejing Aimee; Wacheck, Volker; Smit, Egbert 分享 收藏
The Effects of HER2 Alterations in EGFR Mutant Non-small Cell Lung Cancer Nagasaka, Misako; Singh, Vijendra; Baca, Yasmine; Sukari, Ammar; Kim, Chul; Mamdani, Hirva; Spira, Alexander, I; Uprety, Dipesh; Bepler, Gerold; Kim, Edward S.; Raez, Luis E.; Pai, Sachin Gopalkrishna; Ikpeazu, Chukwuemeka; Oberley, Matthew; Feldman, Rebecca; Xiu, Joanne; Korn, W. Michael; Wozniak, Antoinette J.; Borghaei, Hossein; Liu, Stephen, V 分享 收藏
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HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1 Moses, Niko; Zhang, Mu; Wu, Jheng-Yu; Hu, Chen; Xiang, Shengyan; Geng, Xinran; Chen, Yue; Bai, Wenlong; Zhang, You-Wei; Bepler, Gerold; Zhang, Xiaohong Mary 分享 收藏
ERBB2 alteration with or without co-existent EGFR mutation in metastatic non-small cell lung cancer Singh, Vijendra; Baca, Yasmine; Kim, Seongho; Boumber, Yanis; Mamdani, Hirva; Kim, Edward S.; Sukari, Ammar; Kim, Chul; Bepler, Gerold; Liu, Stephen, V; Spira, Alexander, I; Borghai, Hossein; Nagasaka, Mikaso 分享 收藏
The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53 Hu, Chen; Zhang, Mu; Moses, Niko; Hu, Cong-li; Polin, Lisa; Chen, Wei; Jang, Hyejeong; Heyza, Joshua; Malysa, Agnes; Caruso, Joseph A.; Xiang, Shengyan; Patrick, Steve; Stemmer, Paul; Lou, Zhenkun; Bai, Wenlong; Wang, Chuangui; Bepler, Gerold; Xiaohong Mary Zhang 分享 收藏
Physical activity and quality of life in African American cancer survivors: The Detroit Research on Cancer Survivors study 非裔美国癌症幸存者的身体活动和生活质量: 底特律癌症幸存者研究 Beebe-Dimmer, Jennifer L.; Ruterbusch, Julie J.; Harper, Felicity W. K.; Baird, Tara M.; Finlay, David G.; Rundle, Andrew G.; Pandolfi, Stephanie S.; Hastert, Theresa A.; Schwartz, Kendra L.; Bepler, Gerold; Simon, Michael S.; Mantey, Julia; Abrams, Judy; Albrecht, Teri L.; Schwartz, Ann G. 分享 收藏
HDAC6 regulates DNA damage response via deacetylating MLH1 Zhang, Mu; Hu, Chen; Moses, Niko; Haakenson, Joshua; Xiang, Shengyan; Quan, Daniel; Fang, Bin; Yang, Zhe; Bai, Wenlong; Bepler, Gerold; Li, Guo-Min; Zhang, Xiaohong Mary 分享 收藏
Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor Patki, Mugdha; McFall, Thomas; Rosati, Rayna; Huang, Yanfang; Malysa, Agnes; Polin, Lisa; Fielder, Abigail; Wilson, Mike R.; Lonardo, Fulvio; Back, Jessica; Li, Jing; Matherly, Larry H.; Bepler, Gerold; Ratnam, Manohar 分享 收藏
Prognostic modeling of the immune-centric transcriptome reveals interleukin signaling candidates contributing to differential patient outcomes Watza, Donovan; Lusk, Christine M.; Dyson, Gregory; Purrington, Kristen S.; Chen-, Kang; Wenzlaff, Angela S.; Ratliff, Valerie; Neslund-Dudas, Christine; Bepler, Gerold; Schwartz, Ann G. 分享 收藏
Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity 组蛋白去乙酰化酶6 (HDAC6) 去乙酰化细胞外信号调节激酶1 (ERK1)，从而刺激ERK1活性 Wu, Jheng-Yu; Xiang, Shengyan; Zhang, Mu; Fang, Bin; Huang, He; Kwon, Oh Kwang; Zhao, Yingming; Yang, Zhe; Bai, Wenlong; Bepler, Gerold; Zhang, Xiaohong Mary 分享 收藏
A small molecule inhibits Akt through direct binding to Akt and preventing Akt membrane translocation (vol 285, pg 8383, 2010) Kim, Donghwa; Sun, Mei; He, Lili; Zhou, Qing-Hua; Chen, Jun; Sun, Xia-Meng; Bepler, Gerold; Sebti, Said M.; Cheng, Jin Q. 分享 收藏
Molecular profiling in African American NSCLC patients to identify novel potential driver mutations Schwartz, Ann G.; Wenzlaff, Angela S.; Lusk, Chrissy M.; Dyson, Greg; Bollig-Fischer, Aliccia; Land, Susan; Lata, Sneh; Cote, Michele L.; Bepler, Gerold; Gadgeel, Shirish M. 分享 收藏
Molecular and genomic characterization of SCLC Liu, Stephen V.; Kim, Edward S.; Feldman, Rebecca A.; Gatalica, Zoran; Swensen, Jeffrey; Borghaei, Hossein; Spira, Alexander I.; Bepler, Gerold; Reddy, Sandeep; Dowlati, Afshin 分享 收藏
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