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A

Alessandro Butté

EMD Serono Inc.

36H指数
105论文数
3.4K被引数
收录论文 46
发表时间
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Self-Driving Development of Perfusion Processes for Monoclonal Antibody Production单克隆抗体生产灌注过程的自驱式开发
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2025-12-01
err0
errOAAI
errGadiyar, Chethana Janardhana; Muller, Claudio; Vuillemin, Thomas; Bielser, Jean-marc; Souquet, Jonathan; Fagnani, Alessandro; Sokolov, Michael; von Stosch, Moritz; Feidl, Fabian; Butte, Alessandro; Cruz Bournazou, Mariano Nicolas
err分享
err收藏
Novel calibration design improves knowledge transfer across products for the characterization of pharmaceutical bioprocesses新颖的校准设计可改善产品之间的知识转移，以表征制药生物过程
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-07-12
err0
PREAI
errHelleckes, Laura M.; Wirnsperger, Claus; Polak, Jakub; Guillen-Gosalbez, Gonzalo; Butte, Alessandro; von Stosch, Moritz
err分享
err收藏
An innovative hybrid modeling approach for simultaneous prediction of cell culture process dynamics and product quality
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-03-25
err4
PREAI
errPolak, Jakub; Huang, Zhuangrong; Sokolov, Michael; von Stosch, Moritz; Butte, Alessandro; Hodgman, C. Eric; Borys, Michael; Khetan, Anurag
err分享
err收藏
Modeling of bioprocesses via MINLP-based symbolic regression of S-system formalisms
errCOMPUTERS & CHEMICAL ENGINEERING
IF3.9
err2023-02-01
err5
errOAAI
errForster, Tim; Vazquez, Daniel; Cruz-Bournazou, Mariano Nicolas; Butte, Alessandro; Guillen-Gosalbez, Gonzalo
err分享
err收藏
Comparison of strategies for iterative model-based upstream bioprocess development with single and parallel reactor set-ups
errBIOCHEMICAL ENGINEERING JOURNAL
IF3.8
err2023-02-01
err4
PREAI
errDe Luca, Riccardo; Costa, Goncalo; Narayanan, Harini; Wirnsperger, Claus; Bournazou, Mariano N. Cruz; Butte, Alessandro; von Stosch, Moritz
err分享
err收藏
Hybrid Models Based on Machine Learning and an Increasing Degree of Process Knowledge: Application to Cell Culture Processes基于机器学习和不断增加的过程知识的混合模型: 在细胞培养过程中的应用
errINDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
IF3.9
err2022-06-16
err21
PREAI
errNarayanan, Harini; Luna, Martin; Sokolov, Michael; Butte, Alessandro; Morbidelli, Massimo
err分享
err收藏
Functional-Hybrid modeling through automated adaptive symbolic regression for interpretable mathematical expressions通过自动自适应符号回归对可解释的数学表达式进行功能混合建模
errCHEMICAL ENGINEERING JOURNAL
IF13.2
err2022-02-01
err15
errOAAI
errNarayanan, Harini; Bournazou, Mariano Nicolas Cruz; Gosalbez, Gonzalo Guillen; Butte, Alessandro
err分享
err收藏
Hybrid modeling-a key enabler towards realizing digital twins in biopharma?
errCURRENT OPINION IN CHEMICAL ENGINEERING
IF6.8
err2021-12-01
err34
PREAI
errSokolov, Michael; von Stosch, Moritz; Narayanan, Harini; Feidl, Fabian; Butte, Alessandro
err分享
err收藏
Knowledge transfer across cell lines using hybrid Gaussian process models with entity embedding vectors使用具有实体嵌入向量的混合高斯过程模型跨细胞系的知识转移
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2021-08-12
err26
errOAAI
errHutter, Clemens; Stosch, Moritz; Cruz Bournazou, Mariano N.; Butte, Alessandro
err分享
err收藏
Hybrid Models for the simulation and prediction of chromatographic processes for protein capture用于模拟和预测蛋白质捕获的色谱过程的混合模型
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2021-08-01
err46
errOAAI
errNarayanan, Harini; Seidler, Tobias; Luna, Martin Francisco; Sokolov, Michael; Morbidelli, Massimo; Butte, Alessandro
err分享
err收藏
Hybrid Models Based on Machine Learning and an Increasing Degree of Process Knowledge: Application to Capture Chromatographic Step基于机器学习和不断增加的过程知识的混合模型: 捕获色谱步骤的应用
errINDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
IF3.9
err2021-07-06
err34
PREAI
errNarayanan, Harini; Luna, Martin; Sokolov, Michael; Arosio, Paolo; Butte, Alessandro; Morbidelli, Massimo
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err收藏
Machine Learning for Biologics: Opportunities for Protein Engineering, Developability, and Formulation
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2021-03-01
err89
PREAI
errNarayanan, Harini; Dingfelder, Fabian; Butte, Alessandro; Lorenzen, Nikolai; Sokolov, Michael; Arosio, Paolo
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err收藏
Model based strategies towards protein A resin lifetime optimization and supervision
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2020-08-01
err15
PREAI
errFeidl, Fabian; Luna, Martin F.; Podobnik, Matevz; Vogg, Sebastian; Angelo, James; Potter, Kevin; Wiggin, Elenore; Xu, Xuankuo; Ghose, Sanchayita; Li, Zheng Jian; Morbidelli, Massimo; Butte, Alessandro
err分享
err收藏
Hybrid-EKF: Hybrid model coupled with extended Kalman filter for real-time monitoring and control of mammalian cell culture
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2020-06-16
err59
PREAI
errNarayanan, Harini; Behle, Lars; Luna, Martin F.; Sokolov, Michael; Guillen-Gosalbez, Gonzalo; Morbidelli, Massimo; Butte, Alessandro
err分享
err收藏
Process-wide control and automation of an integrated continuous manufacturing platform for antibodies
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2020-02-17
err70
PREAI
errFeidl, Fabian; Vogg, Sebastian; Wolf, Moritz; Podobnik, Matevz; Ruggeri, Caterina; Ulmer, Nicole; Walchli, Ruben; Souquet, Jonathan; Broly, Herve; Butte, Alessandro; Morbidelli, Massimo
err分享
err收藏
Bioprocessing in the Digital Age: The Role of Process Models
errBIOTECHNOLOGY JOURNAL
IF3.1
err2019-09-23
err159
PREAI
errNarayanan, Harini; Luna, Martin F.; von Stosch, Moritz; Bournazou, Mariano Nicolas Cruz; Polotti, Gianmarco; Morbidelli, Massimo; Butte, Alessandro; Sokolov, Michael
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err收藏
A new generation of predictive models: The added value of hybrid models for manufacturing processes of therapeutic proteins
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2019-07-21
err86
PREAI
errNarayanan, Harini; Sokolov, Michael; Morbidelli, Massimo; Butte, Alessandro
err分享
err收藏
Sequential Multivariate Cell Culture Modeling at Multiple Scales Supports Systematic Shaping of a Monoclonal Antibody Toward a Quality Target
errBIOTECHNOLOGY JOURNAL
IF3.1
err2018-01-30
err49
PREAI
errSokolov, Michael; Morbidelli, Massimo; Butte, Alessandro; Souquet, Jonathan; Broly, Herve
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err收藏
Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2017-03-14
err32
PREAI
errBruhlmann, David; Sokolov, Michael; Butte, Alessandro; Sauer, Markus; Hemberger, Juergen; Souquet, Jonathan; Broly, Herve; Jordan, Martin
err分享
err收藏
Model-based description of peptide retention on doped reversed-phase media
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2015-08-01
err5
PREAI
errKhalaf, Rushd; Forrer, Nicola; Buffolino, Gianluca; Butte, Alessandro; Morbidelli, Massimo
err分享
err收藏

研究方向

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