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Emil R. Unanue

Washington University School of Medicine

118H指数
585论文数
5.0W被引数
收录论文 160
发表时间
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A microenvironment-driven HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes一个微环境驱动的HLA-II相关的胰岛素新抗原在糖尿病中诱导持久的记忆性T细胞激活
errNature Immunology
IF27.6
err2025-11-28
err0
errOAAI
errNeetu Srivastava; Anthony N. Vomund; Rongzhen Yu; Orion J. Peterson; Yuqing Yang; David P. Turicek; Omar Abousaway; Tiandao Li; Lisa Kain; Pamela Stone; Aisha Ansar; Cristina C. Clement; Siddhartha Sharma; Rima Melhem; Bo Zhang; Chang Liu; Alok V. Joglekar; Hao Hu; Chyi-Song Hsieh; Laura Campisi; Laura Santambrogio; Luc Teyton; Emil R. Unanue; Ana Maria Arbelaez; Cheryl F. Lichti; Xiaoxiao Wan
err分享
err收藏
Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death胰腺β细胞有限死亡引起的胰岛巨噬细胞的吞噬性重塑
errNature
IF48.5
err2025-10-01
err0
PREAI
errPavel N. Zakharov; Chanchal S. Chowdhury; Orion J. Peterson; Brady Barron; Anthony N. Vomund; Laurent Gorvel; Emil R. Unanue; Eynav Klechevsky; Xiaoxiao Wan; Kodi S. Ravichandran
err分享
err收藏
Crinophagic granules in pancreatic β cells contribute to mouse autoimmune diabetes by diversifying pathogenic epitope repertoire
errNATURE COMMUNICATIONS
IF15.7
err2024-09-27
err0
errOAAI
errHu, Hao; Vomund, Anthony N.; Peterson, Orion J.; Srivastava, Neetu; Li, Tiandao; Kain, Lisa; Beatty, Wandy L.; Zhang, Bo; Hsieh, Chyi-Song; Teyton, Luc; Lichti, Cheryl F.; Unanue, Emil R.; Wan, Xiaoxiao
err分享
err收藏
CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+T cells in diabetic autoimmunity
errIMMUNITY
IF26.3
err2024-07-01
err5
errOAAI
errSrivastava, Neetu; Hu, Hao; Peterson, Orion J.; Vomund, Anthony N.; Stremska, Marta; Zaman, Mohammad; Giri, Shilpi; Li, Tiandao; Lichti, Cheryl F.; Zakharov, Pavel N.; Zhang, Bo; Abumrad, Nada A.; Chen, Yi-Guang; Ravichandran, Kodi S.; Unanue, Emil R.; Wan, Xiaoxiao
err分享
err收藏
Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load
errCELL REPORTS
IF6.9
err2024-06-01
err2
errOAAI
errNanaware, Padma P.; Khan, Zohaib N.; Clement, Cristina C.; Shetty, Madhur; Mota, Ines; Seltzer, Ethan S.; Dzieciatkowska, Monika; Gamboni, Fabia; D'Alessandro, Angelo; Ng, Charles; Nagayama, Manabu; Lichti, Cheryl F.; Soni, Rajesh K.; Geri, Jacob B.; Matei, Irina; Lyden, David; Longman, Randy; Lu, Theresa T.; Wan, Xiaoxiao; Unanue, Emil R.; Stern, Lawrence J.; Santambrogio, Laura
err分享
err收藏
The 162
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errSrivastava, Neetu; Hu, Hao; Peterson, Orion; Vomund, Anthony; Stremska, Marta; Zaman, Mohammad; Giri, Shilpi; Li, Tiandao; Lichti, Cheryl; Zakharov, Pavel; Zhang, Bo; Abumrad, Nada; Chen, Yi-Guang; Ravichandran, Kodi; Unanue, Emil; Wan, Xiaoxiao
err分享
err收藏
Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms
errDIABETES
IF7.5
err2021-09-08
err11
errOAAI
errSrivastava, Neetu; Hu, Hao; Vomund, Anthony N.; Peterson, Orion J.; Baker, Rocky L.; Haskins, Kathryn; Teyton, Luc; Wan, Xiaoxiao; Unanue, Emil R.
err分享
err收藏
Blood leukocytes recapitulate diabetogenic peptide-MHC-II complexes displayed in the pancreatic islets
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2021-04-06
err12
errOAAI
errVomund, Anthony N.; Lichti, Cheryl F.; Peterson, Orion J.; Arbelaez, Ana Maria; Wan, Xiaoxiao; Unanue, Emil R.
err分享
err收藏
Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice与CD4和CD8 T细胞共生的杀细胞巨噬细胞在NOD小鼠PD-1检查点阻断后引起急性糖尿病
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-11-23
err39
errOAAI
errHu, Hao; Zakharov, Pavel N.; Peterson, Orion J.; Unanue, Emil R.
err分享
err收藏
Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2020-04-06
err92
errOAAI
errZakharov, Pavel N.; Hu, Hao; Wan, Xiaoxiao; Unanue, Emil R.
err分享
err收藏
The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides (vol 21, pg 455, 2020)
errNATURE IMMUNOLOGY
IF27.6
err2020-04-01
err0
errOAAI
errWan, Xiaoxiao; Vomund, Anthony N.; Peterson, Orion J.; Chervonsky, Alexander V.; Lichti, Cheryl F.; Unanue, Emil R.
err分享
err收藏
The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides
errNATURE IMMUNOLOGY
IF27.6
err2020-03-09
err63
errOAAI
errWan, Xiaoxiao; Vomund, Anthony N.; Peterson, Orion J.; Chervonsky, Alexander V.; Lichti, Cheryl F.; Unanue, Emil R.
err分享
err收藏
Position β57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset
errSCIENCE IMMUNOLOGY
IF16.3
err2019-08-02
err44
errOAAI
errGioia, Louis; Holt, Marie; Costanzo, Anne; Sharma, Siddhartha; Abe, Brian; Kain, Lisa; Nakayama, Maki; Wan, Xiaoxiao; Su, Andrew; Mathews, Clayton; Chen, Yi-Guang; Unanue, Emil; Teyton, Luc
err分享
err收藏
The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity
errDIABETES
IF7.5
err2019-07-15
err20
errOAAI
errUnanue, Emil R.; Wan, Xiaoxiao
err分享
err收藏
Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice
errDIABETES
IF7.5
err2018-07-03
err28
errOAAI
errCarrero, Javier A.; Benshoff, Nicholas D.; Nalley, Kimberly; Unanue, Emil R.
err分享
err收藏
Identification of Cross Reactive Insulin Immunogenic Epitopes from Commensal Gut Microbes
errDIABETES
IF7.5
err2018-07-01
err1
PREAI
errAltindis, Emrah; Vomund, Anthony N.; Chow, I-Ting; Damasio, Marcos; Kwok, William; Unanue, Emil R.; Kahn, C. Ronald
err分享
err收藏
The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles
errDIABETOLOGIA
IF10.2
err2018-03-27
err52
errOAAI
errZinselmeyer, Bernd H.; Vomund, Anthony N.; Saunders, Brian T.; Johnson, Michael W.; Carrero, Javier A.; Unanue, Emil R.
err分享
err收藏
Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2017-11-13
err125
errOAAI
errCarrero, Javier A.; McCarthy, Derrick P.; Ferris, Stephen T.; Wan, Xiaoxiao; Hu, Hao; Zinselmeyer, Bernd H.; Vomund, Anthony N.; Unanue, Emil R.
err分享
err收藏
The islet-resident macrophage is in an inflammatory state and senses microbial products in blood
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2017-06-19
err89
errOAAI
errFerris, Stephen T.; Zakharov, Pavel N.; Wan, Xiaoxiao; Calderon, Boris; Artyomov, Maxim N.; Unanue, Emil R.; Carrero, Javier A.
err分享
err收藏
Unique features in the presentation of insulin epitopes in autoimmune diabetes: an update
errCURRENT OPINION IN IMMUNOLOGY
IF5.8
err2017-06-01
err13
PREAI
errWan, Xiaoxiao; Unanue, Emil R.
err分享
err收藏

研究方向

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