Gavin Rumbaugh - Publications, H-index & Citations

Gavin Rumbaugh

university of washington

45H指数

114论文数

9.0K被引数

收录论文 36

发表时间

Mesoscale proximity labeling at chromatin leads to identification of small molecule mechanism of action 染色质上的介观尺度邻近标记导致小分子作用机制的鉴定

Nature Communications

IF15.7

2026-08-24

OAAI

Cameron J. Douglas; Preston Samowitz; Feifei Tong; Alice Long; Caitlin M. Bradley; Laszlo Radnai; David W. C. MacMillan; Courtney A. Miller; Gavin Rumbaugh; Ciaran P. Seath

Genetic Rescue of Disrupted Synaptic Protein Interaction Network Dynamics Following SYNGAP1 Reactivation SYNGAP1再激活后受损突触蛋白相互作用网络动态的遗传拯救

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2026-07-01

PREAI

Stamenkovic, Vera; Harsh, Felicia; Kniffen, Breann; Rumbaugh, Gavin; Smith, Stephen E. P.

The Endo-GeneScreen platform identifies drug-like probes that regulate endogenous protein levels within physiological contexts Endo-GeneScreen平台识别在生理背景下调节内源性蛋白质水平的类药探针

Nature Communications

IF15.7

2025-12-09

OAAI

Preston Samowitz; Laszlo Radnai; Thomas Vaissiere; Sheldon D. Michaelson; Camilo Rojas; Ryan Mitchell; Murat Kilinc; Austin Edwards; Justin Shumate; Richard Hawkins; Virneliz Fernandez-Vega; Timothy P. Spicer; Louis Scampavia; Theodore Kamenecka; Courtney A. Miller; Gavin Rumbaugh

MT-125 Inhibits Non-Muscle Myosin IIA and IIB and Prolongs Survival in Glioblastoma MT-125 抑制非肌性肌球蛋白IIA和IIB并延长胶质母细胞瘤患者的生存期

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Rosenfeld, Steven; Kenchappa, Rajappa; Radnai, Laszlo; Zarco, Natanael; Canoll, Peter; Dovas, Athanassios; Rumbaugh, Gavin; Griffin, Patrick; Kamenecka, Theodore; Miller, Courtney

Development of clinically viable non-muscle myosin II small molecule inhibitors 开发临床可行的非肌球蛋白II小分子抑制剂

Cell

IF42.5

2025-07-01

PREAI

Laszlo Radnai; Erica J. Young; Carlos Kikuti; Katalin Toth; Minghai Zhou; Madalyn Hafenbreidel; Rebecca F. Stremel; Li Lin; Paolo Pasetto; Xiaomin Jin; Aagam Patel; Michael Conlon; Sherri B. Briggs; Leïla Heidsieck; H. Lee Sweeney; James Sellers; Teresa Krieger-Burke; William H. Martin; Jay Sisco; Steven Young; Paul Pearson; Gavin Rumbaugh; Gian Luca Araldi; Steven K. Duddy; Michael D. Cameron; Matthew Surman; Anne Houdusse; Patrick R. Griffin; Theodore M. Kamenecka; Courtney A. Miller

MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastoma MT-125抑制非肌肉肌球蛋白IIA和IIB并延长胶质母细胞瘤患者的生存期

Cell

IF42.5

2025-06-10

OAAI

Rajappa S. Kenchappa; Laszlo Radnai; Erica J. Young; Natanael Zarco; Li Lin; Athanassios Dovas; Christian T. Meyer; Ashley Haddock; Alice Hall; Katalin Toth; Peter Canoll; Naveen K.H. Nagaiah; Gavin Rumbaugh; Michael D. Cameron; Theodore M. Kamenecka; Patrick R. Griffin; Courtney A. Miller; Steven S. Rosenfeld

MT-125 INHIBITS NON-MUSCLE MYOSIN IIA AND IIB, SYNERGIZES WITH ONCOGENIC KINASE INHIBITORS, AND PROLONGS SURVIVAL IN GLIOBLASTOMA

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Rosenfeld, Steven; Kenchappa, Rajappa; Radnai, Laszlo; Zarco, Natanael; Dovas, Athanassios; Haddock, Ashley; Canoll, Peter; Rumbaugh, Gavin; Griffin, Patrick; Kamenecka, Theodore; Miller, Courtney

Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection

ELIFE

IF0

2022-04-08

OAAI

Kilinc, Murat; Arora, Vineet; Creson, Thomas K.; Rojas, Camilo; Le, Aliza A.; Lauterborn, Julie; Wilkinson, Brent; Hartel, Nicolas; Graham, Nicholas; Reich, Adrian; Gou, Gemma; Araki, Yoichi; Bayes, Alex; Coba, Marcelo; Lynch, Gary; Miller, Courtney A.; Rumbaugh, Gavin

Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II

ACS CHEMICAL BIOLOGY

IF3.8

2021-09-24

PREAI

Radnai, Laszlo; Surman, Matthew; Hafenbreidel, Madalyn; Young, Erica J.; Stremel, Rebecca F.; Lin, Li; Bdiri, Bilel; Pasetto, Paolo; Jin, Xiaomin; Geedy, Mackenzie; Partridge, Joni-Rae; Patel, Aagam; Conlon, Michael; Sellers, James R.; Cameron, Michael D.; Rumbaugh, Gavin; Griffin, Patrick R.; Kamenecka, Theodore M.; Miller, Courtney A.

Syngap1 regulates experience-dependent cortical ensemble plasticity by promoting in vivo excitatory synapse strengthening Syngap1通过促进体内兴奋性突触增强来调节依赖经验的皮质整体可塑性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-08-17

OAAI

Llamosas, Nerea; Michaelson, Sheldon D.; Vaissiere, Thomas; Rojas, Camilo; Miller, Courtney A.; Rumbaugh, Gavin

Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-05-04

OAAI

Chen, Jonathan L.; Zhang, Peiyuan; Abe, Masahito; Aikawa, Haruo; Zhang, Liying; Frank, Alexander J.; Zembryski, Timothy; Hubbs, Christopher; Park, HaJeung; Withka, Jane; Steppan, Claire; Rogers, Lucy; Cabral, Shawn; Pettersson, Martin; Wager, Travis T.; Fountain, Matthew A.; Rumbaugh, Gavin; Childs-Disney, Jessica L.; Disney, Matthew D.

MicroRNA regulation of persistent stress-enhanced memory (vol 25, pg 965, 2019)

MOLECULAR PSYCHIATRY

IF10.1

2019-06-28

OAAI

Sillivan, Stephanie E.; Jamieson, Sarah; de Nijs, Laurence; Jones, Meghan; Snijders, Clara; Klengel, Torsten; Joseph, Nadine F.; Krauskopf, Julian; Kleinjans, Jos; Vinkers, Christiaan H.; Boks, Marco P. M.; Geuze, Elbert; Vermetten, Eric; Berretta, Sabina; Ressler, Kerry J.; Rutten, Bart P. F.; Rumbaugh, Gavin; Miller, Courtney A.

A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons

SCIENTIFIC REPORTS

IF3.9

2019-06-21

OAAI

Sridharan, BanuPriya; Hubbs, Christopher; Llamosas, Nerea; Kilinc, Murat; Singhera, Fakhar U.; Willems, Erik; Piper, David R.; Scampavia, Louis; Rumbaugh, Gavin; Spicer, Timothy P.

MicroRNA regulation of persistent stress-enhanced memory

MOLECULAR PSYCHIATRY

IF10.1

2019-05-29

OAAI

UNDERSTANDING DISEASE AND BURDEN IN SYNGAP1-RELATED NON-SYNDROMIC INTELLECTUAL DISABILITY (NSID) PATIENTS USING A PATIENT REGISTRY DATABASE

VALUE IN HEALTH

IF6

2019-05-01

OAAI

Weldon, M.; Holder, J.; Rumbaugh, G.; Smith-Hicks, C.; Boulanger, V; Seebald, A.; Rossov, S.; Milligan, K.; Radtchenko, J.

Re-expression of SynGAP protein in adulthood improves translatable measures of brain function and behavior

ELIFE

IF0

2019-04-26

OAAI

Creson, Thomas K.; Rojas, Camilo; Hwaun, Ernie; Vaissiere, Thomas; Kilinc, Murat; Jimenez-Gomez, Andres; Holder, Jimmy Lloyd, Jr.; Tang, Jianrong; Colgin, Laura L.; Miller, Courtney A.; Rumbaugh, Gavin

Social stress-potentiated methamphetamine seeking

ADDICTION BIOLOGY

IF2.6

2018-08-14

OAAI

Blouin, Ashley M.; Pisupati, Swathi; Hoffer, Colton G.; Hafenbreidel, Madalyn; Jamieson, Sarah E.; Rumbaugh, Gavin; Miller, Courtney A.

The first international conference on SYNGAP1-related brain disorders: a stakeholder meeting of families, researchers, clinicians, and regulators 第一届SYNGAP1-related脑疾病国际会议: 家庭，研究人员，临床医生和监管机构的利益相关者会议

JOURNAL OF NEURODEVELOPMENTAL DISORDERS

IF4

2018-02-05

OAAI

Weldon, Monica; Kilinc, Murat; Holder, J. Lloyd, Jr.; Rumbaugh, Gavin

Susceptibility and Resilience to Posttraumatic Stress Disorder-like Behaviors in Inbred Mice

BIOLOGICAL PSYCHIATRY

IF9

2017-12-01

OAAI

Daws, Stephanie E.; Joseph, Nadine F.; Jamieson, Sarah; King, Michelle L.; Chevere-Torres, Itzamarie; Fuentes, Illeana; Shumyatsky, Gleb P.; Brantley, Alicia F.; Rumbaugh, Gavin; Miller, Courtney A.

Nonmuscle myosin IIB as a therapeutic target for the prevention of relapse to methamphetamine use

MOLECULAR PSYCHIATRY

IF10.1

2015-08-04

OAAI

Young, E. J.; Blouin, A. M.; Briggs, S. B.; Sillivan, S. E.; Lin, L.; Cameron, M. D.; Rumbaugh, G.; Miller, C. A.

研究方向