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Adam M. Sonabend

Northwestern University
H指数:42
被引数:6,355

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Glioma-intrinsic MAPK/ERK signaling promotes immunotherapy efficacy through T cell infiltration and interferon responses

胶质瘤-内在MAPK/ERK信号通过T细胞浸润和干扰素反应促进免疫治疗效果

Nature Communications
IF15.7
2026-06-250
OAAI
Kwang-Soo Kim; Junyi Zhang; Víctor A. Arrieta; Crismita Dmello; Elena Grabis; Yahaya A. Yabo; Si Wang; Karl Habashy; Joseph Duffy; Junfei Zhao; Andrew Gould; Rishi Jain; Li Chen; Jian Hu; Irina Balyasnikova; Dhan Chand; Daniel Levey; Peter Canoll; Wenting Zhao; Peter A. Sims; Raul Rabadan; Surya Pandey; Bin Zhang; Pouya Jamshidi; Catalina Lee-Chang; Dieter Henrik Heiland; Adam M. Sonabend
STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways

STING激活通过炎症性细胞死亡通路诱导脑膜瘤中的细胞毒性及免疫反应

Nature Communications
IF15.7
2026-02-120
OAAI
Mark W. Youngblood; Shashwat Tripathi; Hinda Najem; Harrshavasan Congivaram; Mateo Gomez; Thomas K. Sears; Lisa Hurley; Leah K. Billingham; Caylee Silvers; Wenxia Wang; Deanna Tiek; Nishanth Sadagopan; Rahul Chaliparambil; Qianyi Pu; Ching Man Wai; Abrar Choudhury; Alicia Steffens; Kathleen McCortney; Gustavo Ignacio Vazquez Cervantes; Daniel Oyon; Luis Fernandez; Ashley Selner; Jawad Fares; Matthew Hagan; S. Joy Trybula; Jacky Yeung; Matthieu Peyre; Michel Kalamarides; Peng Zhang; Alexander H. Stegh; David M. Ashley; Craig M. Horbinski; Jared T. Ahrendsen; Pouya Jamshidi; Daniel J. Brat; Rimas V. Lukas; Roger Stupp; Maciej S. Lesniak; Adam M. Sonabend; Gavin P. Dunn; James P. Chandler; Matthew C. Tate; Stephen T. Magill; Jason Miska; Michael A. Curran; David R. Raleigh; Amy B. Heimberger
Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel

血脑屏障开放后细胞外粒子的动态释放预测胶质母细胞瘤对紫杉醇的敏感性

Nature Communications
IF15.7
2025-12-160
OAAI
Mark W. Youngblood; Abha Kumari; Yoon-Tae Kang; Andrew Gould; Karl Habashy; Mateo Gomez; Harika Lingamarla; Trevor Morey; Li Chen; Harrshavasan Congivaram; Rachel Ward; Hui Zhang; Thomas K. Sears; Kathleen McCortney; Katarzyna C. Pituch; Elena M. Torres Ponce; Ashkan Zarrieneh; Mariana Nieves; Sarah Vandermolen; Ditte Primdahl; Karan Dixit; Rimas V. Lukas; Priya Kumthekar; Crismita Dmello; Guillaume Bouchoux; Michael Canney; Christina Amidei; Roger Stupp; Sunitha Nagrath; Adam M. Sonabend
Multi-Omic Profiling of Human Peritumoral Brain Following Ultrasound-Mediated BBB Disruption Reveals Microglial Reprogramming and Enhanced Endothelial Crosstalk

超声介导的血脑屏障破坏后的人体肿瘤周围脑组织的多组学分析揭示了小胶质细胞的重新编程和增强的血管内皮细胞互作

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Arrieta, Victor A.; Habashy, Karl J.; Grabis, Elena; Gallus, Marco; Gomez, Mateo; Luan, Yu; Gould, Andrew; Kim, Kwang-Soo; Najem, Hinda; Dmello, Crismita; Chen, Li; Lee-Chang, Catalina; Canney, Michael; Stupp, Roger; Heimberger, Amy B.; Okada, Hideho; You, Feng; Heiland, Dieter Henrik; Sonabend, Adam M.
YBX1&YBX3 as novel targets to potentiate immune checkpoint blockade response in gliomas

YBX1&YBX3作为增强胶质瘤免疫检查点阻断反应的新型靶点

NEURO-ONCOLOGY
IF13.4
2025-11-010
PRE
Ali, Heba; Zhou, Ningjia; Chen, Li; Van Hijfte, Levi; Tulaiha, Rima; Karri, Vivekanudeep; Zhou, Yalu; Habashy, Karl; Arrieta, Victor A.; Kim, Kwang-Soo; Duffy, Joseph; Yeeravalli, Ragini; Tiek, Deanna M.; Song, Xiao; Mishra, Snehasis; Horbinski, Craig; Lee-Chang, Catalina; Ahmed, Atique; Wang, Lu; Heiland, Dieter Henrik; Sonabend, Adam M.; Dmello, Crismita
Spatial Immunophenotypic Characterization of Immune Exclusion and Dysfunction via Collagen-Rich Fibrous Septa in Chordomas

通过富含胶原的纤维性间隔对脊索瘤中免疫排斥和功能障碍的空间免疫表型表征

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Du, Rebecca; Arrieta, Victor; Benotbatme, Jasim K.; Govind, Sachin; Habashy, Karl J.; Najem, Hinda; Vazquez-Cervantes, Gustavo; Wang, Si; Katz, Joshua; Wan, Hanxiao; Murphy, Alina; Jamshidi, Pouya; Horbinski, Craig; Sonabend, Adam M.; Heimberger, Amy B.; Chandler, James P.; Wolinsky, Jean-Paul; Lee-Chang, Catalina
DECODING THE SPATIAL ARCHITECTURE OF INTEGRATED ELECTROPHYSIOLOGICAL AND TRANSCRIPTOMIC DIVERSITY IN MALIGNANT BRAIN TUMORS

解码恶性脑肿瘤中整合电生理和转录组多样性空间架构

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Grabis, Elena; Hilfiger, Louis; Villa, Giulia; Waldmann, Jean-Philipp; Drexler, Richard; Mancusi, Rebecca; Zhang, Junyi; Yabo, Yahaya A.; Menzl, Lynn; Kueckelhaus, Jan; Peng, Tao; Van Hijfte, Levi; Muhlbauer, Marco; Kastner, Georg; Kong, Youran; Heinrichs, Philipp; Merdan, Ata; Sta, Abdelhamid; Strahle, Jakob; Neidert, Nicolas; Benotmane, Jasim Kada; Reyhan, Ekin; Tetzlaff, Svenja K.; Hambardzumyan, Dolores; Lillo, Sebastian; Daubon, Thomas; Sonabend, Adam M.; Chang, Catalina Lee; Ahmed, Atique; Golebiewska, Anna; Putz, Florian; Bluemcke, Ingmar; Hoffmann, Lucas; Sankowski, Roman; Monje, Michelle; Schnell, Oliver; Beck, Juergen; Prinz, Marco; Vlachos, Andreas; Ricklefs, Franz; Venkataramani, Varun; Heiland, Dieter Henrik
SONOBIRD: A PHASE 3 TRIAL OF BLOOD-BRAIN-BARRIER (BBB) OPENING WITH THE SONOCLOUD-9 IN RECURRENT GLIOBLASTOMA PATIENTS RECEIVING IV CARBOPLATIN

SONOBIRD：一项使用SONOCLOUD-9实现血脑屏障（BBB）开放的第3期临床试验，研究对象为接受静脉注射卡铂治疗的复发性胶质母细胞瘤患者

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Sonabend, Adam; Chinot, Olivier; Duerinck, Johnny; Nunez, Angel Perez; Higgins, Dominique; Geurts, Marjolein; Gill, Brian; Canney, Michael; Desseaux, Carole; Bouchoux, Guillaume; Idbaih, Ahmed; Stupp, Roger; Carpentier, Alexandre
Focused ultrasound-mediated blood-brain barrier disruption, combined with antigen-presenting cell activation, promotes CNS antigen-specific T cell immunity and bypasses immunotherapy resistance mechanism in malignant brain tumors

聚焦超声介导的血脑屏障破坏，结合抗原提呈细胞激活，促进中枢神经系统抗原特异性T细胞免疫，并绕过恶性脑肿瘤的免疫疗法耐药机制。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Gallus, Marco; Yamamichi, Akane; Arrieta, Victor Andres; Nejo, Takahide; Phung, Lan; Saijo, Atsuro; Chuntova, Pavlina; Lu, Jianwen; Phyu, Su; Zhao, Aishi; Okada, Kaori; Watchmaker, Payal; Haegelin, Jeffrey; Lakshmanachetty, Senthilnath; Habashy, Karl; Canney, Michael; Sonabend, Adam M.; Okada, Hideho
Targeting TGFβ-mediated B cell suppression enhances anti-PD-1 efficacy in glioblastoma

靶向TGFβ介导的B细胞抑制可增强胶质母细胞瘤中抗PD-1的疗效

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Hou, David; Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Dapash, Mark; Arrieta, Victor A.; Vazquez-Cervantes, Gustavo, I; Wan, Hanxiao; Billingham, Leah K.; Du, Rebecca; Murphy, Alina R.; Lopez-Rosas, Aurora; Han, Yu; Patel, Ronit, V; Chia, Tzu-Yi; Dmello, Crismita C.; Zhang, Peng; Sheppard, Dean; Sonabend, Adam M.; Miska, Jason M.; Lesniak, Maciej S.; Heiland, Dieter Henrik; Lee-Chang, Catalina
Synergistic STING activation in meningioma neoplastic and immune populations triggers programmed necrosis and modulates the collagen-rich immunosuppressive microenvironment

在脑膜瘤的肿瘤和免疫细胞群体中，协同的STING激活会触发程序性坏死并调节富含胶原的免疫抑制性微环境。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Youngblood, Mark; Tripathi, Shashwat; Najem, Hinda; Congivaram, Harrshavasan; Gomez, Mateo; Sears, Thomas; Hurley, Lisa; Billingham, Leah; Silvers, Caylee; Wang, Wenxia; Tiek, Deanna; Sadagopan, Nishanth; Chaliparambil, Rahul; Pu, Qianyi; Wai, Ching Man; Choudhury, Abrar; Steffens, Alicia; Mccortney, Kathleen; Cervantes, Gustavo; Oyon, Daniel; Fernandez, Luis; Selner, Ashley; Fares, Jawad; Hagan, Matthew; Trybula, Joy; Yeung, Jacky; Peyre, Matthieu; Kalamarides, Michel; Zhang, Peng; Stegh, Alexander; Ashley, David; Horbinski, Craig; Ahrendsen, Jared; Jamshidi, Pouya; Brat, Daniel; Lukas, Rimas; Stupp, Roger; Lesniak, Maciej; Sonabend, Adam; Dunn, Gavin; Chandler, James; Tate, Matthew; Magill, Stephen; Miska, Jason; Curran, Michael; Raleigh, David; Heimberger, Amy
Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial

作者更正: 溶瘤DNX-2401病毒疗法联合pembrolizumab治疗复发性胶质母细胞瘤: 1/2期试验

Nature Medicine
IF50
2025-07-210
OA
Farshad Nassiri; Vikas Patil; Leeor S. Yefet; Olivia Singh; Jeff Liu; Rachel M. A. Dang; Takafumi N. Yamaguchi; Mariza Daras; Timothy F. Cloughesy; Howard Colman; Priya U. Kumthekar; Clark C. Chen; Robert Aiken; Morris D. Groves; Shirley S. Ong; Rohan Ramakrishna; Michael A. Vogelbaum; Simon Khagi; Thomas Kaley; Jason M. Melear; David M. Peereboom; Analiz Rodriguez; Maxim Yankelevich; Suresh G. Nair; Vinay K. Puduvalli; Kenneth Aldape; Andrew Gao; Álvaro López-Janeiro; Carlos E. de Andrea; Marta M. Alonso; Paul Boutros; Joan Robbins; Warren P. Mason; Adam M. Sonabend; Roger Stupp; Juan Fueyo; Candelaria Gomez-Manzano; Frederick F. Lang; Gelareh Zadeh
Dual aVß8 Integrin and PD-1 Blockade Overcomes TGFβ-Mediated B-Cell Suppression to Enhance Anti-Tumor Immunity

双aVß8整合素和PD-1阻断克服TGFβ介导的B细胞抑制以增强抗肿瘤免疫

NEURO-ONCOLOGY
IF13.4
2025-06-011
PRE
Hou, David; Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Dapash, Mark; Arrieta, Victor A.; Vazquez-Cervantes, Gustavo, I; Wan, Hanxiao; Billingham, Leah K.; Du, Rebecca; Murphy, Alina R.; Lopez-Rosas, Aurora; Han, Yu; Patel, Ronit, V; Chia, Tzu-Yi; Dmello, Crismita C.; Zhang, Peng; Sheppard, Dean; Sonabend, Adam M.; Miska, Jason M.; Lesniak, Maciej S.; Heiland, Dieter Henrik; Lee-Chang, Catalina
Integrating Histologic and Molecular Features in Meningiomas
NEUROSURGERY
IF3.9
2025-04-010
PRE
Congivaram, Harrshavasan; Thirunavu, Vineeth; Santana-Santos, Lucas; Jamshidi, Pouya; Chen, William; Nandoliya, Khizar Rehan; Sukhanova, Madina; Smith, Heather; Mccord, Matthew; Steffens, Alicia; Walshon, Jordain; Mccortney, Kathleen; Flowers, Mariah; Wang, Wenxia; Lu, Xinyan; Lesniak, Maciej S.; Sonabend, Adam M.; Tate, Matthew Christopher; Khan, Osaama Hassan; Heimberger, Amy B.; Brat, Daniel J.; Chandler, James P.; Raleigh, David R.; Magill, Stephen T.; Youngblood, Mark; Horbinski, Craig
Endothelial response to blood-brain barrier disruption in the human brain
JCI INSIGHT
IF6.1
2024-12-260
OA
Gould, Andrew; Luan, Yu; Hou, Ye; Korobova, Farida, V; Chen, Li; Arrieta, Victor A.; Amidei, Christina; Ward, Rachel; Gomez, Cristal; Castro, Brandyn; Habashy, Karl; Zhang, Daniel; Youngblood, Mark; Dmello, Crismita; Bebawy, John; Bouchoux, Guillaume; Stupp, Roger; Canney, Michael; Yue, Feng; Iruela-Arispe, M. Luisa; Sonabend, Adam M.
PHARMACOKINETIC ANALYSIS OF CARBOPLATIN AND FLUORESCEIN BRAIN PENETRATION AND PERMANENCE FOLLOWING ULTRASOUND-BASED BLOOD-BRAIN BARRIER OPENING ON GLIOBLASTOMA CLINICAL TRIAL
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Habashy, Karl J.; Synold, Tim; Feng, Ye; Kim, Kwang-Soo; Gomez, Cristal; Amidei, Christina; Ward, Rachel; Vandermolen, Sarah; Zarrieneh, Ashkan; Arrieta, Victor A.; Fares, Jawad; Burdett, Kirsten B.; Zhang, Hui; Dmello, Crismita; Chen, Li; Bebawy, John F.; Canney, Michael; Stupp, Roger; Portnow, Jana; Sonabend, Adam M.
EPIGENETIC POTENTIATION OF ANTI-TUMOR IMMUNE RESPONSES USING VIRAL MIMICRY IN GLIOMAS
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Chandar, Jay; Seetharam, Deepa; Desgraves, Jelisah; Ramsoomair, Christian; Castro, Jesus; Hudson, Anna; Govindarajan, Vaidya; Zhang, Yong; Sonabend, Adam; Valdez, Mynor Mendez; Maric, Dragan; Govindarajan, Vasundara; Rivas, Sarah; Lu, Victor; Alvarado, Alexandra; Tiwari, Ritika; Sharifi, Nima; Demarino, Catherine; Johnson, Kory; de la Fuente, Macarena; Nasany, Ruham Alsiekh; Noviello, Teresa; Ivan, Michael; Komotar, Ricardo; Iavarone, Antonio; Nath, Avindra; Heiss, John; Ceccarelli, Michele; Chiappinelli, Katherine; Figueroa, Maria; Bayik, Defne; Shah, Ashish

研究方向

暂未获取到该数据
V
Víctor A. Arrieta
H 指数:18论文数:176被引数:1,640
R
Roger Stupp
H 指数:114论文数:841被引数:9.1万
C
Catalina Lee-Chang
H 指数:29论文数:215被引数:3,525
C
Crismita Dmello
H 指数:18论文数:165被引数:1,916
C
Craig Horbinski
H 指数:84论文数:806被引数:2.4万
J
Jeffrey N. Bruce
H 指数:77论文数:666被引数:2.2万
M
Maciej S. Lesniak
H 指数:70论文数:554被引数:1.7万
P
Peter Canoll
H 指数:77论文数:675被引数:2.2万
A
Amy B. Heimberger
H 指数:88论文数:680被引数:3.0万
J
Jason Miska
H 指数:31论文数:206被引数:4,333