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镇

镇学初 (Xuechu Zhen)

First Affiliated Hospital of Soochow University

51H指数
211论文数
7.6K被引数
收录论文 125
发表时间
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Decoding the Neural Circuit Underlying Context-Cue Association in Retrieval of Morphine Reward Memory解码支持吗啡奖赏记忆提取中情境线索关联的神经回路
errAdvanced Science
IF14.1
err2026-09-17
err0
errOAAI
errZhifeng Shi; Guangying Li; Qian Yang; Rusun Liu; Linghan Gu; Mingmei Wang; John L. Waddington; Fuhai Ji; Xuechu Zhen
err分享
err收藏
Rational Design of Gi-biased CB1 Agonists for the Next Generation of Analgesic Drug针对下一代镇痛药物的Gi偏向性CB1激动剂的理性设计
errNeuroscience Bulletin
IF5.8
err2026-08-07
err0
PREAI
errNa Ye; Zhi-Feng Shi; Fu-Hai Ji; Xue-Chu Zhen
err分享
err收藏
Structural insights into the MLH1–FAN1 interaction reveal an uncharacterized binding interface on MLH1MLH1–FAN1相互作用的分子结构解析揭示了MLH1上一个未被表征的结合界面
errNature Communications
IF15.7
err2026-07-06
err0
errOAAI
errYichang Chen; Haiyun Hu; Xinci Shang; Keri M. Fishwick; Giada Greco; Qin Xiao; Yinhao Zhou; Qiuyan Huang; Tao Jiang; Xiaolei Huang; Guanghui Wang; Xuechu Zhen; Guoqiang Xu; Su Qin; Alessandro A. Sartori; Yanli Liu
err分享
err收藏
Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processingSirt1通过调控Gli3加工维持Sonic hedgehog信号通路以促进髓母细胞瘤进展
errOncogene
IF7.3
err2026-04-18
err0
PREAI
errJian Hu; Chaonan Zheng; Yingying Feng; Yuhang Li; Panpan Pei; Man Yang; Yanghui Qu; Long-Tai Zheng; Li Zhang; Xue-Chu Zhen; Yuan Wang
err分享
err收藏
De novo design of GPCR exoframe modulatorsGPCR外框架调制器的从头设计
errNature
IF48.5
err2026-02-16
err0
PREAI
errShizhuo Cheng; Jia Guo; Yun-li Zhou; Xumei Luo; Gufang Zhang; Ya-zhi Zhang; Yixin Yang; Jiannan Xie; Ping Xu; Dan-dan Shen; Shaokun Zang; Huicui Yang; Xuechu Zhen; Min Zhang; Yan Zhang
err分享
err收藏
Endosome-phagophore linking assemblies for the degradation of membrane/extracellular proteins内体-吞噬泡连接复合体介导膜蛋白/细胞外蛋白的降解
errNature Communications
IF15.7
err2025-12-22
err0
errOAAI
errPan Wang; Hang Sun; Pei An; Puxian Tang; Qiao Liu; Zini Tang; Taiyong Lv; Jianqing Ruan; Xuechu Zhen; Liang Han
err分享
err收藏
Mechanistic Insights into Pharmacokinetic Interactions between Simvastatin and Vismodegib: Implications for Optimization of Combination Therapy in Medulloblastoma辛伐他汀和维莫德吉药代动力学相互作用的机制探讨：对髓母细胞瘤联合治疗优化的启示
errBiochemical and Biophysical Research Communications
IF2.2
err2025-10-28
err0
PREAI
errChaonan Zheng; Zining Song; Xing Zou; Li Zhang; Wanjun Han; Hao Wu; Jinhui Zhang; Tao Feng; Chunshan Gui; Yuan Wang; Xuechu Zhen
err分享
err收藏
Discovery of New N-H Aporphine Derivatives As Brain-Penetrant Gq-Biased 5-HT2C Receptor Agonists and Dual 5-HT2C/5-HT2A Receptor Agonists发现新型N-H阿波芬因衍生物作为能够穿透血脑屏障的Gq偏向性5-HT2C受体激动剂和双重5-HT2C/5-HT2A受体激动剂
errJournal of Medicinal Chemistry
IF6.8
err2025-10-18
err0
PREAI
errWangzhi Qin; Bingjie Zhang; Qi Wang; Guangqian Jiang; Jiaze Cui; Fan Chen; Ling Wang; Jiaojiao Chen; Sheng Tian; Xue-Chu Zhen; Wenqing Shui; Na Ye
err分享
err收藏
Selective recognition memory impairment in mitochondrial hydroxylase Clk1 mutant mice, rescued by antipsychotics线粒体羟化酶Clk1突变小鼠的选择性识别记忆损伤，可通过抗精神病药物得到恢复
errActa Pharmacologica Sinica
IF8.4
err2025-09-01
err0
PREAI
errZhi-feng Shi; Zhe-xiang Yu; Ling-han Gu; Zhi-xue Ma; Qin-bo Chen; Li-bin Wen; John L. Waddington; Xue-chu Zhen
err分享
err收藏
Serum amyloid A drive microglia shift to a resolving phenotype through Nrf2血清淀粉样蛋白A通过Nrf2驱动小胶质细胞向消散表型转变
errNEUROPHARMACOLOGY
IF4.6
err2025-06-01
err0
PREAI
errLi, Qi; Huang, Yiwei; Ban, Tao; Chen, Kexin; Zhen, Xuechu; Dai, Qijun; Zhang, Gufang
err分享
err收藏
Discovery and proof-of-concept study of a novel highly selective sigma-1 receptor agonist for antipsychotic drug development新型高选择性σ₁受体激动剂的发现及概念验证研究，用于抗精神病药物开发
errActa Pharmaceutica Sinica B
IF14.6
err2025-05-05
err0
errOAAI
errWanyu Tang; Zhixue Ma; Bang Li; Zhexiang Yu; Xiaobao Zhao; Huicui Yang; Jian Hu; Sheng Tian; Linghan Gu; Jiaojiao Chen; Xing Zou; Qi Wang; Fan Chen; Guangying Li; Chaonan Zheng; Shuliu Gao; Wenjing Liu; Yue Li; Wenhua Zheng; Mingmei Wang; Na Ye; Xuechu Zhen
err分享
err收藏
Biomimetic membrane-coated nanoparticles specially permeate the inflammatory blood-brain barrier to deliver plasmin therapy for brain metastases仿生膜涂层纳米颗粒特异地渗透炎症性血脑屏障，以递送plasmin疗法用于脑转移瘤。
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2025-02-01
err1
PREAI
errZhao, Mei; Lin, Yuanyuan; Zeng, Yuteng; Lv, Ziyan; Liang, Jiayu; Tang, Puxian; Zhen, Xuechu; Han, Liang
err分享
err收藏
Macrophage migration inhibitory factor (MIF) in CNS diseases: Functional regulation and potential therapeutic indication
errFUNDAMENTAL RESEARCH
IF6.3
err2024-11-01
err4
errOAAI
errZhang, Yu; Yu, Zhexiang; Ye, Na; Zhen, Xuechu
err分享
err收藏
Current emerging therapeutic targets and clinical investigational agents for schizophrenia: Challenges and opportunities
errMEDICINAL RESEARCH REVIEWS
IF11.6
err2024-09-19
err1
PREAI
errYe, Na; Wang, Qi; Li, Yue; Zhen, Xuechu
err分享
err收藏
Suppressing Wnt signaling of the blood-tumor barrier to intensify drug delivery and inhibit lipogenesis of brain metastases
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-06-01
err5
errOAAI
errTong, Yang; An, Pei; Tang, Puxian; Mu, Rui; Zeng, Yuteng; Sun, Hang; Zhao, Mei; Lv, Ziyan; Wang, Pan; Han, Wanjun; Gui, Chunshan; Zhen, Xuechu; Han, Liang
err分享
err收藏
The NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif
errCELL DEATH & DISEASE
IF9.6
err2024-05-14
err0
errOAAI
errHuang, Xiaolei; Zhang, Cheng; Shang, Xinci; Chen, Yichang; Xiao, Qin; Wei, Zhengguo; Wang, Guanghui; Zhen, Xuechu; Xu, Guoqiang; Min, Jinrong; Shen, Shaoming; Liu, Yanli
err分享
err收藏
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator经典的D1多巴胺受体拮抗剂SCH23390是一种功能性sigma-1受体变构调节剂
errACTA PHARMACOLOGICA SINICA
IF8.4
err2024-04-11
err1
PREAI
errZhang, Gu-fang; Zhu, Kai-lian; Li, Qi; Zhang, Yue; Waddington, John L.; Du, Xiang-dong; Zhen, Xue-chu
err分享
err收藏
Targeting Large-Conductance Calcium-Activated Potassium Channels to Ameliorate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice
errNEUROCHEMICAL RESEARCH
IF3.8
err2024-02-21
err1
PREAI
errLi, Gangjing; Hu, Li; Gu, Xiangcheng; Zhu, Weijun; Zhen, Xuechu; Sun, Xiaohui
err分享
err收藏
Targeted to neuronal organelles for CNS drug development
errADVANCED DRUG DELIVERY REVIEWS
IF17.6
err2023-09-01
err1
PREAI
errYing, Zheng; Ye, Na; Ma, Qilian; Chen, Fan; Li, Ningning; Zhen, Xuechu
err分享
err收藏
DH5α Outer Membrane-Coated Biomimetic Nanocapsules Deliver Drugs to Brain Metastases but not Normal Brain Cells via Targeting GRP94
errSMALL
IF12.1
err2023-04-27
err8
PREAI
errZhou, Mengyuan; Chen, Haiyan; Zeng, Yuteng; Lv, Ziyan; Hu, Xiaoxiao; Tong, Yang; Wang, Pan; Zhao, Mei; Mu, Rui; Yu, Ju; Chen, Yanming; Wei, Lin; Gu, Jiang; Lan, Qing; Zhen, Xuechu; Han, Liang
err分享
err收藏

研究方向

神经精神药理学
合作学者
合作期刊
R
Robert M. Post
H 指数: 126 · 论文数: 828
张
张丽 (Li Zhang)
H 指数: 121 · 论文数: 2.6K
H
Herbert Y. Meltzer
H 指数: 120 · 论文数: 1.1K
J
John R. Speakman
H 指数: 106 · 论文数: 889
蒋
蒋华良 (Hualiang Jiang)
H 指数: 101 · 论文数: 983
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