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I

Itaru Kushima

Nagoya University
H指数:31
被引数:6,660

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荣誉奖项

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A key gene modulating oxytocin efficacy in autism: genome-wide discovery and verification in randomized controlled trials datasets

调节自闭症中催产素效能的关键基因：随机对照试验数据集的全基因组发现与验证

Molecular Psychiatry
IF10.1
2026-03-280
PRE
Hitoshi Kuwabara; Masaki Kojima; Seico Benner; Takeshi Otowa; Takamitsu Watanabe; Miho Kuroda; Keiho Owada; Walid Yassin; Junko Hamada; Yukiko Kano; Yota Uno; Itaru Kushima; Daisuke Mori; Yuko Arioka; Toshio Munesue; Kiyoto Kasai; Haruhiro Higashida; Osamu Abe; Hidemasa Takao; Tomoyasu Wakuda; Yosuke Kameno; Jun Inoue; Taeko Harada; Aya Yamauchi; Nanayo Ogawa; Nami Honda; Saya Kikuchi; Moe Seto; Hiroaki Tomita; Noriko Miyoshi; Megumi Matsumoto; Yuko Kawaguchi; Koji Kanai; Manabu Ikeda; Itta Nakamura; Shuichi Isomura; Yoji Hirano; Toshiaki Onitsuka; Nagahide Takahashi; Mitsuko Nakashima; Hirotomo Saitsu; Kenji Kondo; Masashi Ikeda; Nakao Iwata; Mihoko Shimada; Tsukasa Sasaki; Nori Takei; Norio Ozaki; Hirotaka Kosaka; Takashi Okada; Hidenori Yamasue
The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder

KDM6B相关的神经发育障碍的临床与分子谱

The American Journal of Human Genetics
IF0
2025-10-180
PRE
Dmitrijs Rots; Taryn E. Jakub; Crystal Keung; Adam Jackson; Siddharth Banka; Rolph Pfundt; Bert B.A. de Vries; Richard H. van Jaarsveld; Saskia M.J. Hopman; Ellen van Binsbergen; Irene Valenzuela; Maja Hempel; Tatjana Bierhals; Fanny Kortüm; Francois Lecoquierre; Alice Goldenberg; Jens Michael Hertz; Charlotte Brasch Andersen; Maria Kibæk; Eloise J. Prijoles; Roger E. Stevenson; David B. Everman; Wesley G. Patterson; Linyan Meng; Charul Gijavanekar; Karl De Dios; Shenela Lakhani; Tess Levy; Matias Wagner; Dagmar Wieczorek; Paul J. Benke; María Soledad Lopez Garcia; Renee Perrier; Sergio B. Sousa; Pedro M. Almeida; Maria José Simões; Bertrand Isidor; Wallid Deb; Andrew A. Schmanski; Omar Abdul-Rahman; Christophe Philippe; Ange-Line Bruel; Laurence Faivre; Antonio Vitobello; Christel Thauvin; Jeroen J. Smits; Livia Garavelli; Stefano G. Caraffi; Francesca Peluso; Laura Davis-Keppen; Dylan Platt; Erin Royer; Lisette Leeuwen; Margje Sinnema; Alexander P.A. Stegmann; Constance T.R.M. Stumpel; George E. Tiller; Daniëlle G.M. Bosch; Stephanus T. Potgieter; Shelagh Joss; Miranda Splitt; Simon Holden; Matina Prapa; Nicola Foulds; Sofia Douzgou; Kaija Puura; Regina Waltes; Andreas G. Chiocchetti; Christine M. Freitag; F. Kyle Satterstrom; Silvia De Rubeis; Joseph Buxbaum; Bruce D. Gelb; Aleksic Branko; Itaru Kushima; Jennifer Howe; Stephen W. Scherer; Alessia Arado; Chiara Baldo; Olivier Patat; Demeer Bénédicte; Diego Lopergolo; Filippo M. Santorelli; Tobias B. Haack; Andreas Dufke; Miriam Bertrand; Ruth J. Falb; Angelika Rieß; Peter Krieg; Stephanie Spranger; Maria Francesca Bedeschi; Maria Iascone; Sarah Josephi-Taylor; Tony Roscioli; Michael F. Buckley; Jan Liebelt; Aditi I. Dagli; Emmelien Aten; Anna C.E. Hurst; Alesha Hicks; Mohnish Suri; Ermal Aliu; Sunil Naik; Richard Sidlow; Juliette Coursimault; Gaël Nicolas; Hanna Küpper; Florence Petit; Veyan Ibrahim; Deniz Top; Francesca Di Cara; Raymond J. Louie; Elliot Stolerman; Han G. Brunner; Lisenka E.L.M. Vissers; Jamie M. Kramer; Tjitske Kleefstra
THE ACTIVATED MICROGLIA AND IMPAIRED GLUTAMATERGIC NEUROTRANSMISSION VIA UPREGULATING THE TNF-A/TNFR1 SIGNALING PATHWAY IN THE MICE EXPOSED TO REPEATED SOCIAL DEFEAT STRESS AS JUVENILES

在经历青少年期重复社会 defeat 应激的小鼠中，通过上调 TNF-A/TNFR1 信号通路，表现为小胶质细胞活化及谷氨酸能神经传递受损。

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
IF3.7
2025-02-120
OA
Yoshida, Mikio; Katada, Hikari; Isozumi, Yuya; Kawai, Shunya; Kushima, Itaru; Yoshimi, Akira; Ozaki, Norio; Noda, Yukihiro
Copy number variations in RNF216 and postsynaptic membrane-associated genes are associated with bipolar disorder: a case-control study in the Japanese population
PSYCHIATRY AND CLINICAL NEUROSCIENCES
IF6.2
2024-10-150
OA
Nakatochi, Masahiro; Kushima, Itaru; Aleksic, Branko; Kimura, Hiroki; Kato, Hidekazu; Inada, Toshiya; Torii, Youta; Takahashi, Nagahide; Yamamoto, Maeri; Iwamoto, Kunihiro; Nawa, Yoshihiro; Iritani, Shuji; Iwata, Nakao; Saito, Takeo; Ninomiya, Kohei; Okochi, Tomo; Hashimoto, Ryota; Yamamori, Hidenaga; Yasuda, Yuka; Fujimoto, Michiko; Miura, Kenichiro; Ohi, Kazutaka; Shioiri, Toshiki; Kitaichi, Kiyoyuki; Itokawa, Masanari; Arai, Makoto; Miyashita, Mitsuhiro; Toriumi, Kazuya; Takahashi, Tsutomu; Suzuki, Michio; Kato, Takahiro A.; Kanba, Shigenobu; Horikawa, Hideki; Kasai, Kiyoto; Ikegame, Tempei; Jinde, Seiichiro; Kato, Tadafumi; Kakiuchi, Chihiro; Yamagata, Bun; Nio, Shintaro; Kunii, Yasuto; Yabe, Hirooki; Okamura, Yasunobu; Tadaka, Shu; Fumihiko, Ueno; Obara, Taku; Yamamoto, Yasuyuki; Arioka, Yuko; Mori, Daisuke; Ikeda, Masashi; Ozaki, Norio
Mice with deficiency in Pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature
TRANSLATIONAL PSYCHIATRY
IF6.2
2024-05-281
OAAI
Mori, Daisuke; Inami, Chihiro; Ikeda, Ryosuke; Sawahata, Masahito; Urata, Shinji; Yamaguchi, Sho T.; Kobayashi, Yohei; Fujita, Kosuke; Arioka, Yuko; Okumura, Hiroki; Kushima, Itaru; Kodama, Akiko; Suzuki, Toshiaki; Hirao, Takashi; Yoshimi, Akira; Sobue, Akira; Ito, Takahiro; Noda, Yukikiro; Mizoguchi, Hiroyuki; Nagai, Taku; Kaibuchi, Kozo; Okabe, Shigeo; Nishiguchi, Koji; Kume, Kazuhiko; Yamada, Kiyofumi; Ozaki, Norio
Oxytocin-induced increases in cytokines and clinical effect on the core social features of autism: Analyses of RCT datasets
BRAIN BEHAVIOR AND IMMUNITY
IF7.6
2024-05-010
PRE
Wakuda, Tomoyasu; Benner, Seico; Uemura, Yukari; Nishimura, Tomoko; Kojima, Masaki; Kuroda, Miho; Matsumoto, Kaori; Kanai, Chieko; Inada, Naoko; Harada, Taeko; Kameno, Yosuke; Munesue, Toshio; Inoue, Jun; Umemura, Kazuo; Yamauchi, Aya; Ogawa, Nanayo; Kushima, Itaru; Suyama, Satoshi; Saito, Takuya; Hamada, Junko; Kano, Yukiko; Honda, Nami; Kikuchi, Saya; Seto, Moe; Tomita, Hiroaki; Miyoshi, Noriko; Matsumoto, Megumi; Kawaguchi, Yuko; Kanai, Koji; Ikeda, Manabu; Nakamura, Itta; Isomura, Shuichi; Hirano, Yoji; Onitsuka, Toshiaki; Ozaki, Norio; Kosaka, Hirotaka; Okada, Takashi; Kuwabara, Hitoshi; Yamasue, Hidenori
Phenotypes for general behavior, activity, and body temperature in 3q29 deletion model mice
TRANSLATIONAL PSYCHIATRY
IF6.2
2024-03-071
OAAI
Mori, Daisuke; Ikeda, Ryosuke; Sawahata, Masahito; Yamaguchi, Sho; Kodama, Akiko; Hirao, Takashi; Arioka, Yuko; Okumura, Hiroki; Inami, Chihiro; Suzuki, Toshiaki; Hayashi, Yu; Kato, Hidekazu; Nawa, Yoshihiro; Miyata, Seiko; Kimura, Hiroki; Kushima, Itaru; Aleksic, Branko; Mizoguchi, Hiroyuki; Nagai, Taku; Nakazawa, Takanobu; Hashimoto, Ryota; Kaibuchi, Kozo; Kume, Kazuhiko; Yamada, Kiyofumi; Ozaki, Norio
The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder

KDM6B-related神经发育障碍的临床和分子谱

AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2023-06-0111
OAAI
Rots, Dmitrijs; Jakub, Taryn E.; Keung, Crystal; Lisenka, Vissers E. L. M.; Banka, Siddharth; Pfundt, Rolph; de Vries, Bert B. A.; van Jaarsveld, Richard H.; Hopman, Saskia M. J.; van Binsbergen, Ellen; Valenzuela, Irene; Hempel, Maja; Bierhals, Tatjana; Kortuem, Fanny; Lecoquierre, Francois; Goldenberg, Alice; Hertz, Jens Michael; Andersen, Charlotte Brasch; Kibaek, Maria; Prijoles, Eloise J.; Stevenson, Roger E.; Everman, David B.; Patterson, Wesley G.; Meng, Linyan; Gijavanekar, Charul; De Dios, Karl; Lakhani, Shenela; Levy, Tess; Wagner, Matias; Wieczorek, Dagmar; Benke, Paul J.; Garcia, Maria Soledad Lopez; Perrier, Renee; Sousa, Sergio B.; Almeida, Pedro M.; Simoes, Maria Jose; Isidor, Bertrand; Deb, Wallid; Schmanski, Andrew A.; Abdul-Rahman, Omar; Philippe, Christophe; Bruel, Ange-Line; Faivre, Laurence; Vitobello, Antonio; Thauvin, Christel; Smits, Jeroen J.; Garavelli, Livia; Caraffi, Stefano G.; Peluso, Francesca; Davis-Keppen, Laura; Platt, Dylan; Royer, Erin; Leeuwen, Lisette; Sinnema, Margje; Stegmann, Alexander P. A.; Stumpel, Constance T. R. M.; Tiller, George E.; Bosch, Danielle G. M.; Potgieter, Stephanus T.; Joss, Shelagh; Splitt, Miranda; Holden, Simon; Prapa, Matina; Foulds, Nicola; Douzgou, Sofia; Puura, Kaija; Waltes, Regina; Chiocchetti, Andreas G.; Freitag, Christine M.; Satterstrom, F. Kyle; De Rubeis, Silvia; Buxbaum, Joseph; Gelb, Bruce D.; Branko, Aleksic; Kushima, Itaru; Howe, Jennifer; Scherer, Stephen W.; Arado, Alessia; Baldo, Chiara; Patat, Olivier; Benedicte, Demeer; Lopergolo, Diego; Santorelli, Filippo M.; Haack, Tobias B.; Dufke, Andreas; Bertrand, Miriam; Falb, Ruth J.; Riess, Angelika; Krieg, Peter; Spranger, Stephanie; Bedeschi, Maria Francesca; Iascone, Maria; Josephi-Taylor, Sarah; Roscioli, Tony; Buckley, Michael F.; Liebelt, Jan; Dagli, Aditi I.; Aten, Emmelien; Hurst, Anna C. E.; Hicks, Alesha; Suri, Mohnish; Aliu, Ermal; Naik, Sunil; Sidlow, Richard; Coursimault, Juliette; Nicolas, Gael; Kuepper, Hanna; Petit, Florence; Ibrahim, Veyan; Top, Deniz; Di Cara, Francesca; Louie, Raymond J.; Stolerman, Elliot; Brunner, Han G.; Vissers, Lisenka E. L. M.; Kramer, Jamie M.; Kleefstra, Tjitske
De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues
HUMAN GENETICS
IF3.6
2023-05-172
OAAI
Smits, Daphne J. J.; Schot, Rachel; Popescu, Cristiana A. A.; Dias, Kerith-Rae; Ades, Lesley; Briere, Lauren C. C.; Sweetser, David A. A.; Kushima, Itaru; Aleksic, Branko; Khan, Suliman; Karageorgou, Vasiliki; Ordonez, Natalia; Sleutels, Frank J. G. T.; van der Kaay, Danielle C. M.; Van Mol, Christine; Van Esch, Hilde; Bertoli-Avella, Aida M. M.; Roscioli, Tony; Mancini, Grazia M. S.
Molecular diagnosis of 405 individuals with autism spectrum disorder
EUROPEAN JOURNAL OF HUMAN GENETICS
IF4.6
2023-03-277
OA
Miyake, Noriko; Tsurusaki, Yoshinori; Fukai, Ryoko; Kushima, Itaru; Okamoto, Nobuhiko; Ohashi, Kei; Nakamura, Kazuhiko; Hashimoto, Ryota; Hiraki, Yoko; Son, Shuraku; Kato, Mitsuhiro; Sakai, Yasunari; Osaka, Hitoshi; Deguchi, Kimiko; Matsuishi, Toyojiro; Takeshita, Saoko; Fattal-Valevski, Aviva; Ekhilevitch, Nina; Tohyama, Jun; Yap, Patrick; Keng, Wee Teik; Kobayashi, Hiroshi; Takubo, Keiyo; Okada, Takashi; Saitoh, Shinji; Yasuda, Yuka; Murai, Toshiya; Nakamura, Kazuyuki; Ohga, Shouichi; Matsumoto, Ayumi; Inoue, Ken; Saikusa, Tomoko; Hershkovitz, Tova; Kobayashi, Yu; Morikawa, Mako; Ito, Aiko; Hara, Toshiro; Uno, Yota; Seiwa, Chizuru; Ishizuka, Kanako; Shirahata, Emi; Fujita, Atsushi; Koshimizu, Eriko; Miyatake, Satoko; Takata, Atsushi; Mizuguchi, Takeshi; Ozaki, Norio; Matsumoto, Naomichi
Cross-Disorder Analysis of Genic and Regulatory Copy Number Variations in Bipolar Disorder, Schizophrenia, and Autism Spectrum Disorder
BIOLOGICAL PSYCHIATRY
IF9
2022-09-0130
OA
Kushima, Itaru; Nakatochi, Masahiro; Aleksic, Branko; Okada, Takashi; Kimura, Hiroki; Kato, Hidekazu; Morikawa, Mako; Inada, Toshiya; Ishizuka, Kanako; Torii, Youta; Nakamura, Yukako; Tanaka, Satoshi; Imaeda, Miho; Takahashi, Nagahide; Yamamoto, Maeri; Iwamoto, Kunihiro; Nawa, Yoshihiro; Ogawa, Nanayo; Iritani, Shuji; Hayashi, Yu; Lo, Tzuyao; Otgonbayar, Gantsooj; Furuta, Sho; Iwata, Nakao; Ikeda, Masashi; Saito, Takeo; Ninomiya, Kohei; Okochi, Tomo; Hashimoto, Ryota; Yamamori, Hidenaga; Yasuda, Yuka; Fujimoto, Michiko; Miura, Kenichiro; Itokawa, Masanari; Arai, Makoto; Miyashita, Mitsuhiro; Toriumi, Kazuya; Ohi, Kazutaka; Shioiri, Toshiki; Kitaichi, Kiyoyuki; Someya, Toshiyuki; Watanabe, Yuichiro; Egawa, Jun; Takahashi, Tsutomu; Suzuki, Michio; Sasaki, Tsukasa; Tochigi, Mamoru; Nishimura, Fumichika; Yamasue, Hidenori; Kuwabara, Hitoshi; Wakuda, Tomoyasu; Kato, Takahiro A.; Kanba, Shigenobu; Horikawa, Hideki; Usami, Masahide; Kodaira, Masaki; Watanabe, Kyota; Yoshikawa, Takeo; Toyota, Tomoko; Yokoyama, Shigeru; Munesue, Toshio; Kimura, Ryo; Funabiki, Yasuko; Kosaka, Hirotaka; Jung, Minyoung; Kasai, Kiyoto; Ikegame, Tempei; Jinde, Seiichiro; Numata, Shusuke; Kinoshita, Makoto; Kato, Tadafumi; Kakiuchi, Chihiro; Yamakawa, Kazuhiro; Suzuki, Toshimitsu; Hashimoto, Naoki; Ishikawa, Shuhei; Yamagata, Bun; Nio, Shintaro; Murai, Toshiya; Son, Shuraku; Kunii, Yasuto; Yabe, Hirooki; Inagaki, Masumi; Goto, Yu-ichi; Okumura, Yuto; Ito, Tomoya; Arioka, Yuko; Mori, Daisuke; Ozaki, Norio

研究方向

暂未获取到该数据
N
Norio Ozaki
H 指数:81论文数:1,152被引数:3.5万
B
Branko Aleksić
H 指数:40论文数:293被引数:1.1万
H
Hiroki Kimura
H 指数:23论文数:132被引数:2,041
D
Daisuke Mori
H 指数:42论文数:163被引数:5,139
N
Nakao Iwata
H 指数:81论文数:770被引数:4.3万
M
Masashi Ikeda
H 指数:65论文数:402被引数:3.5万
T
Takashi Okada
H 指数:37论文数:288被引数:5,160
Y
Yuko Arioka
H 指数:23论文数:68被引数:2,167
K
Kanako Ishizuka
H 指数:18论文数:67被引数:1,393
A
Akira Yoshimi
H 指数:17论文数:105被引数:1,287