Susumu Kobayashi - Publications, H-index & Citations

Susumu Kobayashi

harvard medical school

76H指数

1.2K论文数

3.2W被引数

收录论文 201

发表时间

Coopting germline BRCA2 mutation with an available PARP inhibitor to manage resistance to EGFR targeted therapy in EGFR-mutated lung cancer: combination of olaparib with osimertinib 利用可用的PARP抑制剂招募胚系BRCA2突变，以管理EGFR突变型肺癌中针对EGFR靶向治疗的耐药性：奥拉帕利与奥希替尼的联合方案

Clinical Lung Cancer

IF3.3

2026-02-24

PREAI

Hyunwoo Kwon; Hollis Viray; Robert E. Gaudet; Paul A. VanderLaan; Susumu S. Kobayashi; Deepa Rangachari; Daniel B. Costa

A quantitative SPECT/CT metric for diagnosing transthyretin cardiac amyloidosis: multicenter study on biopsy-confirmed cases 一种用于诊断甲状腺素转运蛋白心肌淀粉样变性的定量SPECT/CT指标：基于活检确诊病例的多中心研究

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

IF7.6

2025-04-24

PREAI

Takaishi, Taku; Kisohara, Masaya; Horino, Ryosuke; Kaneko, Hitomi; Hotta, Naohide; Mizuno, Kyosuke; Ezaka, Takamine; Kitagawa, Yuto; Okochi, Sachiko; Kobayashi, Susumu; Kitase, Masanori; Kitada, Shuichi; Urano, Misugi; Hiwatashi, Akio

Efficacy of EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer with EGFR exon 19 insertions: clinical-genomic, preclinical analysis through LC-SCRUM-Asia (multi-institutional genomic screening registry)EGFR酪氨酸激酶抑制剂在携带EGFR外显子19插入突变的非小细胞肺癌患者中的疗效：基于LC-SCRUM-Asia（多机构基因组筛查登记）的临床-基因组学及体外研究分析

LUNG CANCER

IF4.4

2025-04-01

OAAI

Uehara, Yuji; Izumi, Hiroki; Kobayashi, Ikei S.; Matsumoto, Shingo; Hosomi, Yukio; Okuno, Takae; Sugisaka, Jun; Takase, Naoto; Taima, Kageaki; Sasaki, Shinichi; Teranishi, Shuhei; Miyamoto, Shingo; Mori, Masahide; Nakashima, Chiho; Asano, Shuichi; Oi, Hajime; Sakai, Tetsuya; Shibata, Yuji; Udagawa, Hibiki; Sugiyama, Eri; Nosaki, Kaname; Umemura, Shigeki; Zenke, Yoshitaka; Yoh, Kiyotaka; Ikeda, Sadakatsu; Costa, Daniel B.; Kobayashi, Susumu; Goto, Koichi

WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer WEE1使非小细胞肺癌对KRASG12C抑制剂产生耐药性

CANCER LETTERS

IF10.1

2025-02-01

PREAI

Yamamoto, Gaku; Tanaka, Kosuke; Kamata, Ryo; Saito, Hitoshi; Yamamori-Morita, Tomoko; Nakao, Takehiro; Liu, Jie; Mori, Shunta; Yagishita, Shigehiro; Hamada, Akinobu; Shinno, Yuki; Yoshida, Tatsuya; Horinouchi, Hidehito; Ohe, Yuichiro; Watanabe, Shun-Ichi; Yatabe, Yasushi; Kitai, Hidenori; Konno, Satoshi; Kobayashi, Susumu S.; Ohashi, Akihiro

Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer 整合的单细胞rna-seq和空间转录组学分析揭示了EGFR突变的肺癌中与凋亡相关的基因表达谱

CELL DEATH & DISEASE

IF9.6

2024-08-09

OAAI

Izumi, Motohiro; Fujii, Masanori; Kobayashi, Ikei S.; Ho, Vivian; Kashima, Yukie; Udagawa, Hibiki; Costa, Daniel B.; Kobayashi, Susumu S.

The latest policies, practices, and hotspots in research in conjunction with the aging of Japan's population

BIOSCIENCE TRENDS

IF5

2024-06-30

OAAI

Liu, Yuan; Kobayashi, Susumu; Karako, Kenji; Song, Peipei; Tang, Wei

LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion

COMMUNICATIONS BIOLOGY

IF5.1

2024-04-04

OAAI

Mori, Shunta; Izumi, Hiroki; Araki, Mitsugu; Liu, Jie; Tanaka, Yu; Kagawa, Yosuke; Sagae, Yukari; Ma, Biao; Isaka, Yuta; Sasakura, Yoko; Kumagai, Shogo; Sakae, Yuta; Tanaka, Kosuke; Shibata, Yuji; Udagawa, Hibiki; Matsumoto, Shingo; Yoh, Kiyotaka; Okuno, Yasushi; Goto, Koichi; Kobayashi, Susumu

Targeting mtDNA dynamics enhances immunogenicity and sensitizes KRAS mutant cancers to PD-1 blockade

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Tanaka, Kosuke; Adachi, Yasuki; Yoshiya, Miyuki; Owari, Takuya; Yamamori-Morita, Tomoko; Ohashi, Akihiro; Kobayashi, Susumu; Koyama, Shohei; Nishikawa, Hiroyoshi

Comprehensive analysis with single-cell RNA sequence and spatial transcriptomics unravels distinctive expression profile of apoptotic-related genes in EGFR-mutated lung cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Izumi, Motohiro; Fujii, Masanori; Ho, Vivian; Kobayashi, Ikei S.; Kobayashi, Susumu S.

WEE1 inhibition prevents and overcomes resistance to KRAS inhibitors in lung cancer by enhancing MCL1-mediated apoptosis

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Yamamoto, Gaku; Tanaka, Kosuke; Kamata, Ryo; Nakao, Takehiro; Mori, Shunta; Liu, Jie; Kobayashi, Susumu S.; Ohashi, Akihiro

Elucidating the mechanism of resistance to tyrosine kinase inhibitors in ROS1-and ALK-fusion non-small cell lung cancer: The role of CD74

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ho, Vivian; Izumi, Motohiro; Lee, Meghan; Shibahara, Daisuke; Kobayashi, Ikei S.; Kobayashi, Susumu S.

Comparison of diagnosis-related groups (DRG)-based hospital payment system design and implementation strategies in different countries: The case of ischemic stroke 不同国家基于诊断相关分组 (DRG) 的医院付费系统设计和实施策略的比较: 以缺血性卒中为例

BIOSCIENCE TRENDS

IF5

2024-02-29

OAAI

Liu, Yuan; Wang, Gang; Qin, Tian-Ge; Kobayashi, Susumu; Karako, Takashi; Song, Peipei

EML4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-01-29

OAAI

Qin, Zhen; Yue, Meiting; Tang, Shijie; Wu, Fengying; Sun, Honghua; Li, Yuan; Zhang, Yongchang; Izumi, Hiroki; Huang, Hsinyi; Wang, Wanying; Xue, Yun; Tong, Xinyuan; Mori, Shunta; Taki, Tetsuro; Goto, Koichi; Jin, Yujuan; Li, Fei; Li, Fu-Ming; Gao, Yijun; Fang, Zhaoyuan; Fang, Yisheng; Hu, Liang; Yan, Xiumin; Xu, Guoliang; Chen, Haiquan; Kobayashi, Susumu S.; Ventura, Andrea; Wong, Kwok-Kin; Zhu, Xueliang; Chen, Liang; Ren, Shengxiang; Chen, Luo-Nan; Ji, Hongbin

The Impact of On-Target Resistance Mediated by EGFR-T790M or EGFR-C797S on EGFR Exon 20 Insertion Mutation Active Tyrosine Kinase Inhibitors

JTO CLINICAL AND RESEARCH REPORTS

IF3.5

2024-01-01

OAAI

Kobayashi, Ikei S.; Shaffer, William; Viray, Hollis; Rangachari, Deepa; Vanderlaan, Paul A.; Kobayashi, Susumu S.; Costa, Daniel B.

Metabolic Hallmarks for Purine Nucleotide Biosynthesis in Small Cell Lung Carcinoma

MOLECULAR CANCER RESEARCH

IF4.7

2023-09-29

OAAI

Tabata, Sho; Umemura, Shigeki; Narita, Miyu; Udagawa, Hibiki; Ishikawa, Takamasa; Tsuboi, Masahiro; Goto, Koichi; Ishii, Genichiro; Tsuchihara, Katsuya; Ochiai, Atsushi; Kobayashi, Susumu S.; Soga, Tomoyoshi; Makinoshima, Hideki

Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer

FRONTIERS IN ONCOLOGY

IF3.3

2023-09-28

OAAI

Yu, Qian; Kobayashi, Susumu S.; Haeno, Hiroshi

AXL activates YAP through the EGFR-LATS1/2 axis and confers resistance to EGFR-targeted drugs in head and neck squamous cell carcinoma

ONCOGENE

IF7.3

2023-08-17

PREAI

Okamoto, Kento; Ando, Toshinori; Izumi, Hiroki; Kobayashi, Susumu S.; Shintani, Tomoaki; Gutkind, J. Silvio; Yanamoto, Souichi; Miyauchi, Mutsumi; Kajiya, Mikihito

EGFR exon 20 insertion mutations and ERBB2 mutations in lung cancer: a narrative review on approved targeted therapies from oral kinase inhibitors to antibody-drug conjugates 肺癌中的EGFR外显子20插入突变和ERBB2突变: 从口服激酶抑制剂到抗体-药物结合物的已批准靶向治疗的叙述性综述

TRANSLATIONAL LUNG CANCER RESEARCH

IF3.5

2023-07-01

OAAI

Sentana-Lledo, Daniel; Academia, Emmeline; Viray, Hollis; Rangachari, Deepa; Kobayashi, Susumu S.; VanderLaan, Paul A.; Costa, Daniel B.

Molecular mechanisms of early-stage lung adenocarcinoma initiation

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Rodriguez-Fuguet, Alice; Silva, Luis; Asara, John; Li, Xiaoman; Kobayashi, Susumu; Zhang, Wen Cai

AICAR targets oncogenic signaling pathways of MUC1-CT

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Aftab, Fareesa; Rodriguez-Fuguet, Alice; Silva, Luis; Kobayashi, Ikei S.; Sun, Jiao; Politi, Katerina; Levantini, Elena; Zhang, Wei; Kobayashi, Susumu S.; Zhang, Wen Cai

研究方向